Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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N-Acetyl-DL-valine
CAS:Formula:C7H13NO3Purity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:159.19(4-Amino-1-hydroxybutane-1,1-diyl)diphosphonic acid
CAS:Formula:C4H13NO7P2Purity:95%Color and Shape:SolidMolecular weight:249.0960424-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methyl morpholinium chloride
CAS:Formula:C10H17ClN4O3Purity:98%Color and Shape:SolidMolecular weight:276.72D-Alloisoleucine
CAS:Formula:C6H13NO2Purity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:131.189-Fluorenylmethyl Chloroformate [N-Protecting Agent for Peptides Research]
CAS:Formula:C15H11ClO2Purity:>97.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalineMolecular weight:258.70Butanoic acid, 4-oxo-4-[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]-
CAS:Formula:C13H13N3O5S2Purity:%Color and Shape:SolidMolecular weight:355.38941-Acetylguanidine
CAS:Formula:C3H7N3OPurity:>98.0%(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:101.11Clomipramine-13C-d3 HCl
CAS:Formula:C1813CH20D3ClN2·HClColor and Shape:White To Off-White SolidMolecular weight:318.87 36.46(±)-trans Milnacipran HCl
CAS:Formula:C15H22N2O·HClColor and Shape:Off-White SolidMolecular weight:246.35 36.46Cerivastatin Sodium Salt
CAS:Controlled ProductStability Hygroscopic Applications Cerivastatin is a competitive inhibitor of HMG-CoA reductase. References Ness, C.G., et al.: Arch. Biochem. Biophys., 325, 242 (1996), Steinke, W., et al.: Japan. Pharmacol. Ther., 24, Suppl. 9, S1217 (1996),Formula:C26H33FNO5·NaColor and Shape:White To Off-WhiteMolecular weight:481.53N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide
CAS:Controlled ProductApplications N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide was used in the study to discover a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth. N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide is an impurity of Intedanib (I666650), which is an antitumor agent. References Edupuganti, R., et al.: Bioorg. Med. Chem., 25, 2609 (2017); Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)Formula:C29H31N5O2Color and Shape:NeatMolecular weight:481.59Cetirizine Methyl Ester Dihydrochloride (>90%)
CAS:Controlled ProductFormula:C22H27ClN2O3·2ClHPurity:>90%Color and Shape:NeatMolecular weight:475.846Beta-Hydroxy Ethynyl Estradiol
CAS:Controlled ProductImpurity Ethinylestradiol EP Impurity F Applications Ethynyl Estradiol (E685100) impurity F. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Leese, M., et al.: J. Med. Chem., 49, 7683 (2006), Saxena, H., et al.: Steroids, 2007, 72, 892 (2007),Formula:C20H24O3Color and Shape:WhiteMolecular weight:312.40Brompheniramine N-Oxide Maleate
CAS:Formula:C16H19BrN2O·C4H4O4Color and Shape:Off-White SolidMolecular weight:335.25 116.07Candesartan N2-Glucuronide Ditriethylamine Salt
Formula:C30H28N6O9Et3NMolecular weight:616.59 : 2(101.19)(5Z,8Z,12S,14Z)-12-hydroxy-5,8,14-Eicosatrienoic acid methyl ester
CAS:Formula:C21H36O3Molecular weight:336.52rac trans-2-Phenylcyclopropylamine Hydrochloride
CAS:Controlled ProductApplications Non-selective MAO-A/B inhibitor. References Stout, S.C., et al.: J. Pharmacol. Exp. Ther., 300, 1085 (2002),Formula:C9H11N·ClHColor and Shape:NeatMolecular weight:169.654'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide
CAS:Controlled ProductImpurity Telmisartan Bromo Amide Impurity Applications An impurity in the preparation of the angiotensin II receptor antagonist Telmisartan (T017000). References Wienen, W., et al.: Brit. J. Pharmacol., 110, 245 (1993), Neutel, J.M., and Smith, D.H.G.: Adv. Ther., 15, 206 (1998)Formula:C14H12BrNOColor and Shape:WhiteMolecular weight:290.16Nicotine Ditartrate Dihydrate
CAS:Formula:C10H14N2(C4H6O6)(H2O)Molecular weight:162.24 : 2(150.09) : 2(18.02)N-Demethyl Olanzapine-d8
CAS:Controlled ProductApplications A labelled metabolite of Olanzapine.Formula:C162H8H10N4SColor and Shape:NeatMolecular weight:306.4611,12-Dihydro Altrenogest
CAS:Controlled ProductFormula:C21H28O2Color and Shape:NeatMolecular weight:312.446Regorafenib N-Oxide (M2 Metabolite)
CAS:Formula:C21H15ClF4N4O4Color and Shape:White To Off-White SolidMolecular weight:498.82L-Lysine,N6-[[(2-chlorophenyl)methoxy]carbonyl]-N2-[(1,1-dimethylethoxy)carbonyl]-
CAS:Formula:C19H27ClN2O6Purity:98%Color and Shape:SolidMolecular weight:414.8805N-Benzoyl-L-glutamic Acid
CAS:Formula:C12H13NO5Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:251.243,3',5-triiodo-L-thyronine
CAS:Formula:C15H12I3NO4Purity:98%Color and Shape:SolidMolecular weight:650.973494-[[2-(Octyloxy)benzoyl]amino]benzoic Acid
CAS:Controlled ProductFormula:C22H27NO4Color and Shape:NeatMolecular weight:369.4541-Palmitoyl-2-oleyl-sn-glycero-3-phospho-rac-(1-glycerol) Sodium Salt
CAS:Formula:C40H76NaO10PPurity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:771.00DL-p-Hydroxyphenyllactic Acid-d3
CAS:Controlled ProductApplications DL-p-Hydroxyphenyllactic Acid-d3 is the isotope labelled analog of DL-p-Hydroxyphenyllactic Acid (H953665); a reagent in the synthesis of 2-O-(4-coumaroyl)-3-(4-hydroxyphenyl)lactic acid which is an important intermediate of rosmarinic acid biosynthesis. References Matsuno, M., et al.: Chem. Pharm. Bull., 49, 1644 (2001)Formula:C9H7D3O4Color and Shape:NeatMolecular weight:185.193-Carboxy-alpha-methylbenzeneacetic Acid(Ketoprofen Impurity)
CAS:Impurity Ketoprofen EP Impurity C; Ketoprofen USP Compound C: (2-(3-Carboxyphenyl)propionic Acid) Applications 3-Carboxy-α-methylbenzeneacetic Acid (Ketoprofen EP Impurity C) is a impurity of Ketoprofen (K200800). Ketoprofen USP Compound C: (2-(3-Carboxyphenyl)propionic Acid) References Dvorak, J., et al.: J. Pharm. Biomed. Anal., 36, 625 (2004), Allegretti, M., et al.: J. Med. Chem., 48, 4312 (2005),Formula:C10H10O4Color and Shape:Off-WhiteMolecular weight:194.18Enalapril Maleate
CAS:Formula:C20H28N2O5·C4H4O4Color and Shape:White To Off-White SolidMolecular weight:376.46 116.071(2H)-Quinolinecarboxylic acid, 2-ethoxy-, ethyl ester
CAS:Formula:C14H17NO3Purity:95%Color and Shape:SolidMolecular weight:247.2897
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