Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide-d6
CAS:Controlled ProductApplications Isotope labelled 7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide is an impurity in the synthesis of Tiotropium Bromide (T444850), a muscarinic receptor antagonist. Bronchodilator. References Rodgers, T. et al.: J. Med. Chem., 20, 591 (1977); Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006);Formula:C19D6H16NO4S2Color and Shape:Off-WhiteMolecular weight:398.549(3R,4'S)-Benidipine HCl
CAS:Formula:C28H31N3O6·HClColor and Shape:Yellow SolidMolecular weight:505.58 36.46Ciprofloxacin Hydrochloride Monohydrate
CAS:Formula:C17H18FN3O3·HCl·H2OPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:385.83Loratadine Related Compound A (8-Chloro-5,6-dihydro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C19H19ClN2Color and Shape:White Off-White Crystalline PowderMolecular weight:310.12368Triclosan Methyl-d3 Ether
CAS:Controlled ProductApplications A bactericide detected in rivers and lakes. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Lindstrom, A., et al.: Environ. Sci. Technol., 36, 2322 (2002)Formula:C132H3H6Cl3O2Color and Shape:NeatMolecular weight:306.59Argatroban Impurity 94
Formula:C13H15NO5SColor and Shape:White To Off-White SolidMolecular weight:297.33Travoprost USP Related Compound A (Travoprost Acid)
CAS:Formula:C23H29F3O6Color and Shape:Colorless LiquidMolecular weight:458.471,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane [Hydroxyl Protecting Agent]
CAS:Formula:C12H28Cl2OSi2Purity:>97.0%(GC)Color and Shape:Colorless to Almost colorless clear liquidMolecular weight:315.43Imidazole
CAS:Impurity Ondansetron EP Impurity E / Clotrimazole EP Impurity D Applications Imidazole (Ondansetron EP Impurity E) is a versatile heterocycle used in the preparation of various biologically active compounds such as the amino acid histidine and is present in many antifungal medication. It is also used extensively as a corrosion inhibitor on transition metals such as copper. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Arispe, N. et al.: Biophys. J., 95, 4879 (2008); Troesken, E.R. et al.: Endo. Res., 30, 387 (2004); Otmacic Curkovic, H. et al.: Corr. Sci., 51, 2342 (2009);Formula:C3H4N2Color and Shape:Off WhiteMolecular weight:68.082,4,6-Tris(trifluoromethyl)benzamide
CAS:Controlled ProductApplications 2,4,6-Tris(trifluoromethyl)benzamide is an intermediate in the synthesis of 2,4,6-Tris(trifluoromethyl)aniline (T876695). 2,4,6-Tris(trifluoromethyl)aniline, is a Fluorinated substituents that have become valuable tool in medical chemistry. It can also be used for the preparation of azo dyes containing fluorine. References Gandel'sman, L. Z., et al.: Ukrainskii Khimicheskii , 41, 61 (1975); Edelbach, B. L., et al.: Synthesis, 44, 3595 (2012)Formula:C10H4F9NOColor and Shape:NeatMolecular weight:325.13N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide
CAS:Formula:C13H18N2O5SPurity:98%Color and Shape:SolidMolecular weight:314.3574Methyl DL-2-Aminobutyrate Hydrochloride
CAS:Formula:C5H11NO2·HClPurity:>98.0%(N)Color and Shape:White to Almost white powder to lumpMolecular weight:153.61Pravastatin Sodium
CAS:Formula:C23H35NaO7Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:446.521,2-Dibromo-4-(1,2-dibromoethyl)cyclohexane
CAS:Controlled ProductApplications Tetrabromoethylcyclohexane (TBECH) is an additive brominated flame retardant used in domestic and industrial applications. It was used to investigate the biodegradation kinetics in aerobic and anaerobic soil. References Ahn, M., et al.: Environ. Sci. Tech., 40, 215 (2006), Nyholm, J., et al.: Environ. Toxicol. Chem., 28, 1035 (2009),Formula:C8H12Br4Color and Shape:NeatMolecular weight:427.804-Hydroxybenzenepropanoic Acid
CAS:Formula:C9H10O3Color and Shape:White To Off-White SolidMolecular weight:166.18Gemcitabine
CAS:Formula:C9H11F2N3O4Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:263.20Vilanterol Trifenatate
CAS:Formula:C24H33Cl2NO5·C20H16O2Color and Shape:White To Off-White SolidMolecular weight:486.43 288.35Bis(2-ethylhexyl)maleate (Maleic acid, bis(2-ethylhexyl)ester)
CAS:Maleic acid not in us note 3 section 6Formula:C20H36O4Color and Shape:LiquidMolecular weight:340.51Gatifloxacin Related Compound A (1-Cyclopropyl-6-fluoro-8-hydroxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid)
CAS:Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, nesoiFormula:C18H20FN3O4Color and Shape:Yellow SolidMolecular weight:361.14378Labetalol 1-Carboxylic Acid Hydrochloride
CAS:Controlled ProductFormula:C19H23NO4·ClHColor and Shape:NeatMolecular weight:365.854,4'-Dimethoxytrityl chloride
CAS:Formula:C21H19ClO2Purity:98%Color and Shape:SolidMolecular weight:338.8274Ref: IN-DA0033UZ
5g21.00€10g25.00€1kg206.00€25g25.00€50g33.00€5kgTo inquire100g56.00€10kgTo inquire250g77.00€500g111.00€50kgTo inquireRef: 4Z-P-398054
Discontinued productDi(2-Ethylhexyl) Azelate-d14
CAS:Formula:C25H34D14O4Color and Shape:Pale Yellow LiquidMolecular weight:426.74Rufloxacin HCl
CAS:Formula:C17H18FN3O3S·HClColor and Shape:Pale Yellow SolidMolecular weight:363.41 36.467-Demethyl Ivabradine Hydrochloride
CAS:Controlled ProductApplications Ivabradine (I940500) metabolite. References Duffull, S., et al.: Eur. J. Pharm. Sci., 10, 285 (2000), Portoles, A., et al.: J. Clin. Pharmacol., 46, 1195 (2006),Formula:C26H34N2O5·HClColor and Shape:NeatMolecular weight:491.02
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