Phthalate Standards

Applications Diethyl Phthalate-d14 is the isotope labelled analog of Diethyl Phthalate, which is a phthalate metabolite with genotoxic effect. References Reyes, F., et al.: J. Clin. Endocrinol. Metab., 37, 74 (1973), Engel, S., et al.: Neurotoxicology, 30, 522 (2009),

Applications 2-Ethyl-1-hexanol is used in the preparation of succinate-based plasticizers for replacing phthalate plasticizers. Also used in the preparation of polymeric plasticizers. References Stuart, A. et al.: Eur. Polym. J. 49, 2785 (2013); Braslau, R. et al.: J. Polym. Sci. Part. A. Polym. Chem., 51, 1175 (2013);

Applications Monoisopropyl Phthalate-d4, is the labeled analogue of Monoisopropyl Phthalate (M547900), which is shown to have anti-estrogenic activities. References Okubo, T., et al.: Bio. Pharmace. Bulletin, 26 (8), 1219 (2003);

Applications Monobenzyl Terephthalate is a reactant in the preparation of benzoyl-glucopyranosyl ureas as glycogen phosphorylase inhibitors and potential antidiabetic agents M onobenzyl Terephthalate is also an intermediate formed in the synthesis of Cyclotris(1,4-butylene Terephthalate) (C988975), a cyclic trimer of poly(butylene terephthalate), a thermoplastic engineering polymer. References Nagy, V., et. al.: Bioorg. Med. Chem., 20, 1801 (2012); East, G.C. et al.: Polymer, 23, 323 (1982)

Applications Labelled analogue of Di-n-propyl Phthalate, a phthalate metabolite of Di-n-butyl phthalate (D429495) degradation with potential genotoxic effect. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Fromme, H. et al.: Environ. Int., 37, 715 (2011); Cao, X.-L.: Comp. Rev. Food Sci. Food Safety, 9, 21 (2010); Begum, A. et al.: Chem. Lett., 33, 682 (2004);

Stability Moisture Sensitive Applications Tricresyl Phosphate is an organophosphorus compound often used as a flame retardant and plasticizer. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Wei, G., et al.: Environ. Pollut., 196, 29 (2015)

Applications One of the several phthalate esters which showed clear fetotoxicity, embryolethality and teratogenicity. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications A glucuronide conjugate of the phthalate metabolite Monoethyl Phthalate (M542585). References Silva, M.J. et all.: Arch. Toxicol., 77, 561 (2003); Samandar, E. et al.: Env. Res., 109, 641 (2009);

Applications Monoundecyl Phthalate is a phthalate monoesters on gap junctional intercellular communication and peroxisome proliferation in rodent and primate hepatocyte. References Kamendulis, L.M., et al.: J. Toxicol. Environ. Health., 65, 569 (2002);

Applications A Phthalate metabolite. References Ye, X., et al.: Environ. Res., 108, 260 (2008), Blair, J., et al.: Environ. Sci. Technol., 43, 6262 (2009), Clewell, R., et al.: Toxicol. n Vitro, 24, 327 (2010),

Applications Diallyl Phthalate is used as a reagent in ring-closing ruthenium based reactions. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References De Clercq, B. et al.: Tetra. Lett., 42, 8959 (2001); De Clercq, B. et al.: Tetrahedron Lett., 43, 9101 (2002);

Applications Dimethyl Isophthalate-2,4,5,6-d4 (CAS# 1007509-57-0) is a useful isotopically labeled research compound.

Applications Phthalate metabolite. References Ye, X., et al.: Environ. Res., 108, 260 (2008), Engel, S., et al.: NeuroToxicol., 30, 522 (2009), Samandar, E., et al.: Environ. Res., 109, 641 (2009),

Applications Phthalate metabolite. References Ye, X., et al.: Environ. Res., 108, 260 (2008), Engel, S., et al.: NeuroToxicol., 30, 522 (2009), Samandar, E., et al.: Environ. Res., 109, 641 (2009),

Applications Bis[(±)-2-ethylhexyl] Phthalate-d38 (CAS# 352431-42-6) is a useful isotopically labeled research compound.

Applications Labelled Diisopentyl Phthalate (D455230). One of the several phthalate esters which showed clear fetotoxicity, embryolethality and teratogenicity. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Hellwig, J., et al.: Food Chem. Toxicol., 35, 501 (1997),

Applications A labelled metabolite of Di-n-pentyl phthalate (DPP), used mainly as a plasticizer in nitrocellulose. References Schmid, P., et al.: Xenobiotica, 1985, 15, 251 (1985), Nativelle, C., et al.: Food Chem. Toxicol., 37, 905 (1999), Howdeshell, K., et al.: Toxicol. Sci., 105, 153 (2008),

Applications 1,2-Benzenedicarboxylic Acid Hexyl Octyl Ester is an phthalate esters used as plasticizers and additives. Used in toxiciology studies as well as risk assessment studies of food contamination that occurs via migration of phthalates into foodstuffs from food-contact materials (FCM). References Kumar, R., et al.: Am. Lab., 31, 32 (1999);

Applications Di-n-Butylphthalate (DBP) (M525100) glucuronide metabolite. References Shen, O., et al.: Toxicol. Lett., 191, 9 (2009), Aylward, L., et al.: Reg. Toxicol. Pharmacol., 55, 259 (2009), Beydon, D., et al.: Toxicol. in Vitro, 24, 71 (2010),

Applications An isotope labelled derivative of Mono(2-ethyl-5-hydroxyhexyl) Phthalate (M542510), a phthalate metabolite. References Ye, X., et al.: Environ. Res., 108, 260 (2008), Engel, S., et al.: NeuroToxicol., 30, 522 (2009), Samandar, E., et al.: Environ. Res., 109, 641 (2009), Anderson, W., et al.: Food Chem. Toxicol., 49, 2022 (2011),

Impurity Acetylsalicylic Acid EP Impurity B/ Salicylic Acid Related Compound B Applications 4-Hydroxyisophthalic acid has been proposed as an improvement over aspirin. An impurity of Acetylsalicylic acid (A187780). Acetylsalicylic Acid Impurity B; Aspirin Impurity B References Chester, et al.: Nature, 206, 175 (1955),