Phthalate Standards

Applications 1,2,4-Benzenetricarboxylic Acid 1,2-Bis(2-ethylhexyl) Ester is an analog of Trioctyl Trimellitate (T804400) which is a plasticizer that was evaluated for endocrine disrupting activities through estrogen receptor alpha binding assay. References Riddick, W.: J. Coating. Technol., 55, 57 (1983); Ito, R., et al.: Int. J. Pharma., 360, 91 (2008); Ohashi, A., et al.: J. Artific. Organs., 8, 252 (2005);

Applications Diisopropyl Phthalate-d4, is the labeled analogue of Diisopropyl Phthalate (D459450), a volatile components present in essential oils of various plants. Also used in the synthesis of enantioenriched C2-symmetric molecules. References Mahatheeranont, S., et al.: Kasetsart Journal: Natural Sci., 29 (4), 508 (1995); Kurashov, E. A., et al.: Rastitel'nye Resursy, 49 (1), 85 (2013); Castaldi, M. P., et al.: Euro. J. Org. Chem., 8, 1867 (2006);

Applications Isotope labelled Diundecyl Phthalate is a phthalate diester and has been investigated for its toxicology in male rats for risk assessment. References Kwack, S.J., et al.: J. Toxicol. Environ. Health., 72, 1446 (2009); Serafimova, R., et al.: Chem. Res. Toxiciol., 20, 662 (2007);

Applications 3α,12α-Dihydroxy-5β-chol-9(11)-enic Acid is used in the analysis and in the structure determination of unsaturated 5β-cholanoic acids. References Kuksis, A., et al.: Lipids, 15, 770 (1980)

Stability Very Hygroscopic Applications Mono(5-carboxy-2-ethylpentyl) Phthalate is a metabolite of Bis(2-ethylhexyl) Phthalate (DEHP) (B433850). References Engel, S., et al.: NeuroToxicol., 30, 522 (2009), Hernandez-Diaz, S., et al.: Environ. Health Perspectives, 117, 185 (2009), Berman, T., et al.: Environ. Int., 35, 353 (2009),

Applications Disecoctyl phthalate (cas# 131-15-7) is a useful research chemical.

Applications Labelled compound of a widely used chemical with potential thyroid-disrupting properties. Used in toxicology studies as well as risk assessment studies of food contamination that occurs via migration of phthalates into foodstuffs from food-contact materials (FCM). References Boas, M. et al.: Env. Health Persp., 118, 1458 (2010); Petersen, J.H. et al.: Food Add. Contam. Part A Chem. Anal. Cont. Expos. Risk. Assess., 27, 1608 (2010); Kwack, S.J. et al.: Toxicol. Res., 26, 75 (2010);

Applications A widely used chemical with potential thyroid-disrupting properties. Used in toxicology studies as well as risk assessment studies of food contamination that occurs via migration of phthalates into foodstuffs from food-contact materials (FCM). References Boas, M. et al.: Env. Health Persp., 118, 1458 (2010); Petersen, J.H. et al.: Food Add. Contam. Part A Chem. Anal. Cont. Expos. Risk. Assess., 27, 1608 (2010); Kwack, S.J. et al.: Toxicol. Res., 26, 75 (2010);

Applications Monoethyl-d5 Phthalate-d4 is an isotope labeled analog of Monoethyl Phthalate, which is a Phthalate metabolite. References Engel, S., et al.: NeuroToxicol., 30, 522 (2009), Aylward, L., et al.: Reg. Toxicol. Pharmacol., 55, 259 (2009), Blair, J., et al.: Environ., Sci. Technol., 43, 6262 (2009),

Applications Cyphenothrin is used in pesticidal compositions. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Bernardi, G., et al.: Talanta, 161, 40 (2016); Lu, H., et al.: Zhonghua Weisheng Shachong Yaoxie, 21, 242 (2015)

Applications Pyronil 45 is a brominated phthalate derivative used in flame-retardant polyvinyl chloride compositions. Flame Retardant References Davis, E., et al.: Environ. Sci. Technol., 43, 5739 (2009),

Applications Mono(2-hydroxyisobutyl)phthalate is a metabolite of Di-isobutyl phthalate. References Engelhardt, G., et al.: Chemosphere, 6, 347 (1977),

Applications Phthalic Acid Bis(3,7-dimethyloctyl) Ester-d4 is the isotope labelled analog of Phthalic Acid Bis(3,7-dimethyloctyl) Ester (P384535); a diester derivative of Phthalic Acid (P384480) which can be used as a plasticizer for PVC-type compositions. References Takeuchi, H., et al. Jpn. Kokai Tokkyo Koho. JP 2001002829 A 20010109. Jan 9, 2001

Applications Labelled Monohexyl Phthalate is a phthalate ester that was used to characterize human salivary esterase in enzymatic hydrolysis. References Niino, T., et al.: J. Health. Sci., 49, 76 (2003); Moss, E.J., et al.: Toxicol. Lett., 40, 77 (1988);

Applications Di(n-butyl-d9) 1,10-Decanedioate is a useful isotopically labeled compound of Dibutyl Sebacate (D429525(P)). Dibutyl Sebacate (DBS) is a dibutyl ester of sebacic acid. Dibutyl Sebacate can be used for plastics in use in the food packaging industry, in plastics used for medical devices, and for pharmaceutical applications. Dibutyl Sebacate is also used as a desensitizer in Otto fuel II, a torpedo monopropellant. References Eriksson, M., et al.: Plant Physiol., 132, 732 (2003), ,,Beuve, N., et al.: Plant Cell Environ., 27, 1035 (2004),

Phthalic acid (1,2-Benzenedioic acid) is an aromatic dicarboxylic acid. It is a human xenobiotic metabolite.

Applications Isotope labelled Diallyl Phthalate is used as a reagent in ring-closing ruthenium based reactions. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References De Clercq, B. et al.: Tetrahedron Lett., 42, 8959 (2001); De Clercq, B. et al.: Tetrahedron Lett., 43, 9101 (2002);

Stability Volatile Applications Xylene, is the precursor for Terephthalic Acid and Dimethyl Terephthalate, both monomers used in the production of polyethylene terephthalate (PET) plastic bottles and polyester clothing. It can also be used as a solvent. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Tremblay, J. F., et al.: Chem. Eng. News, 89 (38), 18 (2011); Clark, J. E., et al.: Ind. End. Chem., 47 (2), 250 (1955);

Applications Diethyl Phthalate-d14 is the isotope labelled analog of Diethyl Phthalate, which is a phthalate metabolite with genotoxic effect. References Reyes, F., et al.: J. Clin. Endocrinol. Metab., 37, 74 (1973), Engel, S., et al.: Neurotoxicology, 30, 522 (2009),

Applications 2-Ethyl-1-hexanol is used in the preparation of succinate-based plasticizers for replacing phthalate plasticizers. Also used in the preparation of polymeric plasticizers. References Stuart, A. et al.: Eur. Polym. J. 49, 2785 (2013); Braslau, R. et al.: J. Polym. Sci. Part. A. Polym. Chem., 51, 1175 (2013);

Applications Monoisopropyl Phthalate-d4, is the labeled analogue of Monoisopropyl Phthalate (M547900), which is shown to have anti-estrogenic activities. References Okubo, T., et al.: Bio. Pharmace. Bulletin, 26 (8), 1219 (2003);