Peptides

Histone H3 (1-21) K9Me2 is derived from Histone 3 (H3) which is one of the four core histones (H2A, H2B, H3 and H4) fundamental in compacting eukaryotic DNA into the nucleosome. The nucleosome arises when 147 base pairs of DNA wrap around a H3-H4 tetramer and two H2A-H2B dimers, forming the histone octamer core. Both H4 and H3 are highly conserved and perform roles in binding to segments of DNA which enter and leave the nucleosome and in chromatin formation. Similar to the other core histone, H3 has a globular domain and a flexible N-terminal domain, 'histone tail' which can undergo modifications such as acetylation, methylation, phosphorylation and ubiquitination. Due to histones containing a large number of lysine and arginine residues they have a positive net charge which interacts in an electrostatic manner with the negatively charged phosphate groups in DNA. The transcriptional activation or silencing of the chromatin is controlled by ATP-dependent chromatin remodelling factors and histone modifying enzymes which target histone proteins. Both processes function to alter to change the positioning of the nucleosome, allowing the DNA it to be either available to the transcription machinery or inaccessible.The Histone H3 (1-21) lysine 9 has been dimethylated.

Peptide H-APIIAVTR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-APIIAVTR-OH include the following: Polytrauma induces increased expression of pyruvate kinase in neutrophils R Oehler, G Weingartmann, N Manhart - Blood, The Journal , 2000 - ashpublications.orghttps://ashpublications.org/blood/article-abstract/95/3/1086/138709 Desenvolvimento de metodos de proteacaŽmica dirigida e sua aplicaaca§aca£o na quantificaaca§aca£o de paineis proteicos GP Lanfredi - 2017 - teses.usp.brhttps://www.teses.usp.br/teses/disponiveis/17/17131/tde-17042018-143452/?gathStatIcon=true

Peptide H-TLQALEFHTVPFQLLAR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-TLQALEFHTVPFQLLAR-OH include the following: Systematic analysis of the cerebrospinal fluid proteome of fibromyalgia patients PE Khoonsari , S Musunri, S Herman, CI Svensson - Journal of , 2019 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S1874391918301738 Systematic quantification of peptides/proteins in urine using selected reaction monitoring N Selevsek, M Matondo , MS Carbayo - , 2011 - Wiley Online Libraryhttps://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/pmic.201000599

Peptide H-GAQASPPPIAPYPSPTR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-GAQASPPPIAPYPSPTR-OH include the following: Development and application of a multiple reaction monitoring method for the simultaneous quantification of sodium channels Nav1.1, Nav1.2, and Nav1.6 in R Kwan, P Das, N Gerrebos , J Li - Rapid , 2024 - Wiley Online Libraryhttps://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/rcm.9672

A synthetic peptide for use as a blocking control in assays to test for specificity of SLC38A3 antibody, catalog no. 70R-7037

A synthetic peptide for use as a blocking control in assays to test for specificity of GSR antibody, catalog no. 70R-5268

PEN (human) aceate, one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83.

Mambalgin-2 (Mamb-2), a venom peptide sourced from the African black mamba, acts as an inhibitor of acid-sensitive ion channels (ASICs).

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Peptide H-TELLPGDRDNLAIQTR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-TELLPGDRDNLAIQTR-OH include the following: Purification and molecular cloning of prostacyclin-stimulating factor from serum-free conditioned medium of human diploid fibroblast cells T Yamauchi, F Umeda, M Masakado, M Isaji - Biochemical , 1994 - portlandpress.comhttps://portlandpress.com/biochemj/article-abstract/303/2/591/31336 Proteomic screen identifies IGFBP7 as a novel component of endothelial cell-specific Weibel-Palade bodies D Van Breevoort, EL van Agtmaal - Journal of proteome , 2012 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/pr300010r

Peptide H-ILENLKDCGLF-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-ILENLKDCGLF-OH include the following: Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II X Deupi , P Edwards, A Singhal - Proceedings of the , 2012 - National Acad Scienceshttps://www.pnas.org/doi/abs/10.1073/pnas.1114089108 Helix formation in arrestin accompanies recognition of photoactivated rhodopsin SE Feuerstein, A Pulvermüller, R Hartmann - Biochemistry, 2009 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/bi900544p X-ray structure breakthroughs in the GPCR transmembrane region S Topiol, M Sabio - Biochemical pharmacology, 2009 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0006295209001130 Active-state models of ternary GPCR complexes: determinants of selective receptor-G-protein coupling RC Kling, H Lanig , T Clark, P Gmeiner - PloS one, 2013 - journals.plos.orghttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0067244 Active-State Models of Ternary GPCR Complexes: Determinants of Selective Receptor-G-Protein RC Kling, H Lanig , T Clark, P Gmeiner - 2013 - Citeseerhttps://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&doi=cf8d6785a2ee57eb6f305218f9087d6b677915ed Crystal structure of opsin in its G-protein-interacting conformation P Scheerer , JH Park, PW Hildebrand , YJ Kim, N Krauss - Nature, 2008 - nature.comhttps://www.nature.com/articles/nature07330 The cytoplasmic rhodopsin-protein interface: potential for drug discovery N Yanamala , E Gardner , A Riciutti - Current Drug , 2012 - ingentaconnect.comhttps://www.ingentaconnect.com/content/ben/cdt/2012/00000013/00000001/art00002 Crystal structure of a common GPCR-binding interface for G protein and arrestin M Szczepek , F Beyriacašre, KP Hofmann, M Elgeti - Nature , 2014 - nature.comhttps://www.nature.com/articles/ncomms5801 X-ray structure developments for GPCR drug targets M Sabio, SW Topiol - 2010 - books.google.comhttps://books.google.com/books?hl=en&lr=&id=sj5bXlebi0MC&oi=fnd&pg=PA434&dq=(%22H-ILENLKDCGLF-OH%22+OR+%22ILENLKDCGLF%22+OR+%22NH2-Ile-Leu-Glu-Asn-Leu-Lys-Asp-Cys-Gly-Leu-Phe-OH%22)+AND+peptide&ots=YenLS653ie&sig=k_sw895pYHpn9cQOc3UBwWQVDxs Conserved Tyr2235.58 Plays Different Roles in the Activation and G-Protein Interaction of Rhodopsin M Elgeti , R Kazmin, M Heck, T Morizumi - Journal of the , 2011 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ja200545n Crystal structure of constitutively active rhodopsin: How an agonist can activate its GPCR J Standfuss, PC Edwards, A D'Antona, M Fransen - Nature, 2011 - ncbi.nlm.nih.govhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715716/ The structural basis of agonist-induced activation in constitutively active rhodopsin J Standfuss , PC Edwards, A D'Antona, M Fransen - Nature, 2011 - nature.comhttps://www.nature.com/articles/nature09795 Supplementary Figure 1| Crystal and UV/vis spectra of Meta II. a, Meta II crystal D Absorbance - researchgate.nethttps://www.researchgate.net/profile/Patrick-Scheerer/publication/235955116_Choe-Scheerer-Ernst-Nature-2011-SI/links/00463514b6fbf3d328000000/Choe-Scheerer-Ernst-Nature-2011-SI.pdf Mutation of Phe318 within the NPxxY(x)5,6F motif in melanin-concentrating hormone receptor 1 results in an efficient signaling activity A Hamamoto, M Horikawa, T Saho - Frontiers in , 2012 - frontiersin.orghttps://www.frontiersin.org/articles/10.3389/fendo.2012.00147/full Molecular dynamics simulations of the effect of the G-protein and diffusible ligands on the beta2-adrenergic receptor A Goetz, H Lanig , P Gmeiner , T Clark - Journal of molecular biology, 2011 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0022283611011399

Peptide H-ALYEQEIR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-ALYEQEIR^-OH include the following: Direct evidence of phosphorylated neuronal intermediate filament proteins in neurofibrillary tangles (NFTs): phosphoproteomics of Alzheimer's NFTs P Rudrabhatla , H Jaffe, HC Pant - The FASEB Journal, 2011 - ncbi.nlm.nih.govhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205835/ Superoxide dismutase catalyzes nitration of tyrosines by peroxynitrite in the rod and head domains of neurofilament-L JP Crow, YZ Ye, M Strong , M Kirk - Journal of , 1997 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1046/j.1471-4159.1997.69051945.x Cerebrospinal fluid neurofilament light chain as a biomarker in neuroaxonal damage: Comparing and analysing quantification with two analytical assays J Ask - 2020 - gupea.ub.gu.sehttps://gupea.ub.gu.se/handle/2077/64164

Please enquire for more information about Nesfatin-1 (mouse) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

A synthetic peptide for use as a blocking control in assays to test for specificity of LOC344065 antibody, catalog no. 70R-9046

Enfuvirtide acetate salt is a linear synthetic peptide made of 36 amino acids. It has an acetylated N-terminus and a carboxamide C-terminus.

Peptide H-GRTGRRNSI-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-GRTGRRNSI-NH2 include the following: Selective sensing of phosphorylated peptides and monitoring kinase and phosphatase activity with a supramolecular tandem assay Y Liu , J Lee, L Perez , AD Gill , RJ Hooley - Journal of the , 2018 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/jacs.8b08693 PKB inhibition prevents the stimulatory effect of insulin on glucose transport and protein translocation but not the antilipolytic effect in rat adipocytes U Smith, E Carvalho , E Mosialou, F Beguinot - Biochemical and , 2000 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0006291X00921454 A structural comparison of inhibitor binding to PKB, PKA and PKA-PKB chimera TG Davies, ML Verdonk , B Graham - Journal of molecular , 2007 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0022283607000058 High-level expression of functional cGMP-dependent protein kinase using the baculovirus system R Feil , S Muller, F Hofmann - FEBS letters, 1993 - Elsevierhttps://www.sciencedirect.com/science/article/pii/001457939381632A Expression of cGMP-dependent protein kinase in Escherichia coli R Feil , M Bigl, P Ruth, F Hofmann - Reversible Protein Phosphorylation in , 1993 - Springerhttps://link.springer.com/chapter/10.1007/978-1-4615-2600-1_6 Insights into nucleotide binding in protein kinase A using fluorescent adenosine derivatives NI DA QUN, J Shaffer, JA Adams - Protein Science, 2000 - cambridge.orghttps://www.cambridge.org/core/journals/protein-science/article/insights-into-nucleotide-binding-in-protein-kinase-a-using-fluorescent-adenosine-derivatives/A232E098C64BF7D50C384AE4D05158E7 Structural basis for peptide binding in protein kinase A: role of glutamic acid 203 and tyrosine 204 in the peptide-positioning loop MJ Moore, JA Adams , SS Taylor - Journal of Biological Chemistry, 2003 - ASBMBhttps://www.jbc.org/article/S0021-9258(19)32548-7/abstract Assay of protein kinases and phosphatases using specific peptide M Ruzzene , LA PINNA - Protein Phosphorylation: A Practical , 1999 - books.google.comhttps://books.google.com/books?hl=en&lr=&id=Hz_2HV1GWfMC&oi=fnd&pg=PA221&dq=(%22H-GRTGRRNSI-NH2%22+OR+%22NH2-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ser-Ile-amide%22+OR+%22GRTGRRNSI%22)+AND+peptide&ots=4vYj07anH1&sig=6F3M4v5R3GJa7dbf-0Q689w-x0M Cloning of a Fibroblast Growth Factor Receptor 1 Splice Variant from Xenopus Embryos That Lacks a Protein Kinase C Site Important for the Regulation of Receptor LL Gillespie, G Chen, GD Paterno - Journal of Biological Chemistry, 1995 - ASBMBhttps://www.jbc.org/article/S0021-9258(18)90024-4/abstract Ligand-gated split-kinases K Camacho-Soto, J Castillo-Montoya - Journal of the , 2014 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ja4130803 Kinetic and catalytic mechanisms of protein kinases JA Adams - Chemical reviews, 2001 - ACS Publicationshttps://pubs.acs.org/doi/full/10.1021/cr000230w Participation of ADP dissociation in the rate-determining step in cAMP-dependent protein kinase J Zhou, JA Adams - Biochemistry, 1997 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/bi971438n Is there a catalytic base in the active site of cAMP-dependent protein kinase? J Zhou, JA Adams - Biochemistry, 1997 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/bi9619132 Detection of conformational changes along the kinetic pathway of protein kinase A using a catalytic trapping technique J Shaffer, JA Adams - Biochemistry, 1999 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/bi991109q Regulation of sarcoplasmic reticulum Ca2+ ATPase 2 (SERCA2) activity by phosphodiesterase 3A (PDE3A) in human myocardium: phosphorylation-dependent F Ahmad , W Shen, F Vandeput - Journal of Biological , 2015 - ASBMBhttps://www.jbc.org/article/S0021-9258(20)76757-8/fulltext Phosphorylation and activation of a transducible recombinant form of human HSP20 in Escherichia coli CR Flynn , CC Smoke, E Furnish, P Komalavilas - Protein expression and , 2007 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S1046592806002634 Pim kinase substrate identification and specificity C Peng, A Knebel, NA Morrice, X Li - The journal of , 2007 - academic.oup.comhttps://academic.oup.com/jb/article-abstract/141/3/353/2182327 Enzyme activity assays for protein kinases: strategies to identify active substrates BA Haubrich, DC Swinney - Current drug discovery , 2016 - ingentaconnect.comhttps://www.ingentaconnect.com/content/ben/cddt/2016/00000013/00000001/art00003 Phosphorylation of NF-κB proteins by cyclic GMP-dependent kinase: A noncanonical pathway to NF-κB activation B He, G F. Weber - European journal of biochemistry, 2003 - Wiley Online Libraryhttps://febs.onlinelibrary.wiley.com/doi/abs/10.1046/j.1432-1033.2003.03574.x

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool