Peptides

μ-Conotoxin SxIIIC, an irreversible NaV channel inhibitor, is derived from Conus striolatus and is useful in researching neurological disorders, including

Peptide H-SVLLDAASGQLR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-SVLLDAASGQLR-OH include the following: Putative phospholipase B-like 2 is not responsible for polysorbate degradation in monoclonal antibody drug products S Zhang , H Xiao, M Goren, D Burakov, G Chen - Journal of , 2020 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0022354920303051 Putative Phospholipase B-like 2 (PLBD2) is not responsible for polysorbate degradation in monoclonal antibody drug products D Burakov, N Li - Authorea Preprints, 2020 - advance.sagepub.comhttps://advance.sagepub.com/doi/full/10.22541/au.158316267.76227928

Peptide Ac-EEEPQEEIPYLELLP-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using Ac-EEEPQEEIPYLELLP-NH2 include the following: Increased Activity of c-Src and Csk in Fibroblasts Transformed by v-src Oncogene Z Tuhačkova, M Vojtěchova, J Hlavaček - Biochemical and , 2002 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0006291X01962473

Kv and SK channels blocker

This C-terminal Sortagging peptide acts as a (oligo)glycine nucleophile in the final steps of a sortagging protein labelling reaction. This reaction results in the fluorescent moiety being attached to the C-terminus of the target protein or peptide.A substrate peptide containing the LPXTG motif is recognised and cleaved by the enzyme Sortase A (SrtA) from Staphylococcus aureus. The catalytic cysteine residue in the active site of SrtA, serves as a nucleophile to cleave the peptide bond between threonine and glycine of the substrate peptide. Cleavage results in the formation of a thioacyl intermediate between the substrate peptide and SrtA. This intermediate is then resolved by the N-terminus of this (oligo)glycine nucleophile peptide, resulting in the creation of a new peptide bond that links the substrate peptide to this peptide and its fluorescent dye.  This method of protein labelling is known as sortagging.This peptide contains Sulfocyanine5, which is a fluorescent red dye.

Please enquire for more information about H-2kb tetramer peptide - OVA including the price, delivery time and more detailed product information at the technical inquiry form on this page

Peptide H-VAIDAGYR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-VAIDAGYR^-OH include the following: Quantitative analysis of the human AKR family members in cancer cell lines using the mTRAQ/MRM approach S Zhang , B Wen , B Zhou, L Yang, C Cha - Journal of Proteome , 2013 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/pr301153z

A synthetic peptide for use as a blocking control in assays to test for specificity of RAD54B antibody, catalog no. 70R-5653

Catalogue peptide; min. 95% purity

H-Arg-Gly-Asp-Cys-OH is a biomimetic amino acid that possesses the same three-dimensional structure as the amino acid sequence found in the human epidermal growth factor receptor 2 (HER2). This compound has been shown to inhibit the activity of enzymes, such as kinases, which are involved in cancer cell division. It also can be used to target and destroy cancer cells using gene therapy. H-Arg-Gly-Asp-Cys-OH binds to messenger RNA and inhibits its translation into protein, which may lead to cell death. H-Arg-Gly-Asp-Cys -OH has been shown to bind specifically with HER2 receptors on breast cancer cells and promote their destruction by inducing apoptosis. HARGAIN: 3DCTKP PRODUCT

BMP 4 Human is a recombinant human protein that is a member of the TGF-β superfamily. It interacts with Ligand, Receptor, and Activator and has been shown to inhibit Ion channels in vitro. BMP 4 Human is a research tool for studying signaling pathways in pharmacology and cell biology.

Peptide H-SLDNGGYYISPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-SLDNGGYYISPR^-OH include the following: Development of Label-free Quantification by Mass Spectrometry Methodology to Measure Lyn Phosphorylation Stoichiometry LL Jin - 2009 - collectionscanada.gc.cahttps://www.collectionscanada.gc.ca/obj/thesescanada/vol2/002/MR52691.PDF?oclc_number=728824517

Peptide H-FYFENALSK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-FYFENALSK-OH include the following: Dual kinase-mediated regulation of PITK by CaMKII and GSK3 NC Kwiek, DF Thacker, TAJ Haystead - Cellular signalling, 2007 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0898656806002038

A synthetic peptide for use as a blocking control in assays to test for specificity of AKR1D1 antibody, catalog no. 70R-10186

Vasoactive intestinal peptide (VIP) is a neuropeptide found throughout the body and the central nervous system (CNS). VIP is located within cell bodies and nerve endings of the enteric nervous system, brain and pancreas. VIP neurons in the peripheral system fire to regulate blood vessels, and the  CNS innervate cerebral vasculature. VIP  binds to G protein-coupled receptors VPAC1 and VPAC2. VIP and VPAC2 are detected in circular smooth muscle cells of cerebral arterioles. VIP and VPAC1 are also found in lymphatic tissue. VIP can block inflammation, modify the Th response favouring Th2 and induce regulatory T cells. Overexpression of each receptor has been linked to various cancers.VIP administration leads to pancreatic bicarbonate-rich fluid secretion but not to the same degree stimulated by secretin. VIP stimulates insulin secretion in a glucose-dependent manner and also stimulates glucagon secretion. Studies have found that in morbidly obese patients, VIP levels are lowered and work to slow gastric and duodenal motility but increase gastric emptying. Therefore, decreasing VIP levels in obese patients may increase weight gain by accelerating gastric emptying.VIP has been well studied in pancreatic acini. VIP is a full agonist of amylase secretion and increases cyclic AMP synchronised with an increase in intracellular Ca2+ triggered by stimuli that act through cholecystokinin (CCK) or cholinergic agonists. Most cAMP increases, and amylase secretion appear to be mediated via VPAC1.The discovery of VPAC antagonists can help to understand VIPs roles and may also provide new therapies in VIP dysregulated systems such as cancers. VIP (6-28) is a specific competitive inhibitor of the VIP receptor derived from VIP. VIP-induced vasodilatation was blocked by co-administration of the VIP receptor antagonist VIP (6-28). Using a VIP receptor antagonist has made VIP function easier to study during neuronal injury, inflammation, and heart innervation. The VIP receptor antagonist is being considered for osteoarthritis treatment, an area with no current treatments other than analgesics.

Peptide H-HKKKHPDASV^NFSE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-HKKKHPDASV^NFSE-OH include the following: Quantification of serum high mobility group box 1 by liquid chromatography/high-resolution mass spectrometry: implications for its role in immunity, inflammation, and L Weng, L Guo , A Vachani, C Mesaros - Analytical , 2018 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acs.analchem.8b01175

A synthetic peptide for use as a blocking control in assays to test for specificity of Morf4l1 antibody, catalog no. 70R-8722

A synthetic peptide for use as a blocking control in assays to test for specificity of KIAA0182 antibody, catalog no. 70R-4413