Peptides

Diethylcyanomethylphosphonate is a hydrochloric acid salt of diethylcyanomethylphosphonic acid. It is used in the asymmetric synthesis of many organic molecules, including pharmaceuticals, and has been shown to have antiviral properties. Diethylcyanomethylphosphonate binds to the receptor on the surface of cells and inhibits their growth. This may be due to its ability to block the binding of sodium ions to cell receptors. The drug also prevents hydroxyl group metabolism and has been shown to be active against infectious diseases such as HIV and malaria.

A synthetic peptide for use as a blocking control in assays to test for specificity of QPCT antibody, catalog no. 70R-5342

Nemifitide acetate, synthetic 5-amino acid antidepressant, has quick effect, mimics MIF.

APL180 (L-4F) is an apolipoprotein A-I mimetic peptide that enhances the anti-inflammatory activity of high-density lipoprotein (HDL). It is applicable for cardiovascular disease research.

Peptide H-YLNEAVFNFV-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-YLNEAVFNFV-OH include the following: NeoHeadHunter: an algorithm for the detection, ranking and probabilistic classification of neoepitope candidates X Zhao - bioRxiv, 2023 - biorxiv.orghttps://www.biorxiv.org/content/10.1101/2023.10.25.563895.abstract

The optimal proteolytic substrate for mucosa-associated lymphoid tissue 1 (MALT1). MALT1 is an arginine-specific protease which cleaves after the C-terminal arginine residue. This peptide can be used to test MALT1 protease activity with the addition of an appropriate C-terminal tag.MALT1 has both adaptor and protease functions and is involved in controlling antigen receptor-mediated signalling to nuclear factor KB (NF-KB). When activated, MALT1 forms a complex with B-cell lymphoma/leukemia 10 (BCL10) and caspase recruitment domain-containing protein 11(CARD11)/CARD-containing MAGUK protein 1 (CARMA1), which results in NF-KB nuclear translocation. The protease function of MALT1 promotes gene transcription by inactivating negative regulators of NF-KB and JNK signalling, such as A20, RELB and CYLD. MALT1-dependent cleavage of the RNAse MCPIP1 (also known as Regnase-1) is then thought to lead to the stabilization of the resulting transcripts.

Galanin (1-30) is an endogenous neuropeptide with endocrine, metabolic and behavioural effects. Galanin has a role in intestinal smooth muscle contraction, insulin and somatostatin release, and synaptic neurotransmission.Galanin is widely distributed in the central nervous, peripheral, and endocrine systems. Galanin's overarching function is as an inhibitory, hyper-polarizing neuromodulator for classical neurotransmitters like acetylcholine and serotonin. Galanin interacts with 3 receptor subtypes, GalR1-3 G protein-coupled receptors inserted into the plasma membrane. GalR1 is believed to activate a Gβγ pathway to regulate MAPK activation. GalR2 can also activate the MAPK pathway, but unlike GalR1, there is detectable inositol phosphate production. GalR3 is associated with the G alpha i/o pathway receptor activation leads to a cellular influx of K+. Each receptor has been associated with neurological diseases such as GalR3 and epilepsy.Galanin protects against various physiological insults in vitro, including excitotoxicity and β-amyloid toxicity. Changes in galanin have been widely studied concerning Alzheimer's disease, and galaninergic neurons are spared in late-stage Alzheimer's relative to non-galaninergic neurones.Galanin (1-30) has been used as an agonist for the GalR2 receptor in vitro for calcium mobilisation assays to understand the role Galanin/GalR2 play in multiple sclerosis.An N-terminal cysteine residue has been included on the galanin (1-30) peptide to allow ease of site-specific conjugation to various molecules.

Peptide Ac-SNKYLDGNANKSTSDGSC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using Ac-SNKYLDGNANKSTSDGSC-NH2 include the following: Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines E Billy , V Brondani, H Zhang - Proceedings of the , 2001 - National Acad Scienceshttps://www.pnas.org/doi/abs/10.1073/pnas.261562698

A synthetic peptide for use as a blocking control in assays to test for specificity of CAB39L antibody, catalog no. 70R-10167

Peptide H-HNLFEPEDTGQR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-HNLFEPEDTGQR^-OH include the following: Characterization of seminal plasma proteomic alterations associated with the IVF and rescue-ICSI pregnancy in assisted reproduction X Liu , G Liu, P Zhu, Y Wang, J Wang, W Zhang- ..., 2020 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1111/andr.12687 Quantification of human kallikrein-2 in clinical samples by selected reaction monitoring Á Végvári , K Sjodin, M Rezeli - Journal of proteome ..., 2013 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/pr400423k

A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF546 antibody, catalog no. 70R-8163

Caerulein, desulfated ammonium is a desulfated Caerulein formed by hydrolysis of Caerulein stimulating lipase secretion and inhibits gastric acid secretion.

SARS-CoV-2 Spike RBD 319-335 peptide is an epitope of interest of the SARS-CoV-2 Spike S glycoprotein Receptor-Binding Domain (RBD). SARS-CoV-2 Spike RBD 319-335 peptide is useful for vaccine development and for structure-activity relationship studies SARS-CoV-2 Spike (S) glycoprotein Spike (S) glycoprotein corresponds to one of the leading targets for COVID-19 disease. Present on the surface of Sars-CoV-2 virus, Spike S protein is a class I fusion protein that allows the virus to enter host cells. With a 1 273 aa length, Spike protein has 2 subunits : S1 contains the receptor-binding domain RBD and S2 induces the fusion of the viral envelop with the cellular membrane. SARS-CoV-2 Spike RBD: The receptor-binding domain in SARS-CoV-2 Spike protein allows binding to the Angiotensin-Converting Enzyme receptor 2 (ACE2 receptor) which mediates the viral entry. SB-PEPTIDE also offers SARS-CoV-2 Spike RBD 319-335 (Biotin-LC) peptide

Boc-Hyp(Bzl)-OH is a synthetic peptide that is used as a pharmacological research tool. It is an inhibitor of the ion channel Kv1.2, which is a voltage-gated potassium channel found in the central nervous system and peripheral tissues. Boc-Hyp(Bzl)-OH binds to the extracellular loop 2 of Kv1.2, blocking the flow of potassium ions through the channel and inhibiting its function. This peptide has been shown to inhibit cell proliferation and induce cell death in various cancer cells, such as breast carcinoma cells and lymphoma cells.

Peptide H-ESNGPVKVWGSIK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-ESNGPVKVWGSIK-OH include the following: Deamidation of asparagine to aspartate destabilizes Cu, Zn superoxide dismutase, accelerates fibrillization, and mirrors ALS-linked mutations Y Shi , NR Rhodes, A Abdolvahabi , T Kohn - Journal of the , 2013 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ja407801x Development and characterization of human and mouse specific antibodies to CuZn-superoxide dismutase (SOD1) SE Bartlett , R Singala, A Hashikawa, L Shaw - Journal of neuroscience , 2000 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0165027000001898 A ditryptophan cross-link is responsible for the covalent dimerization of human superoxide dismutase 1 during its bicarbonate-dependent peroxidase activity DB Medinas , FC Gozzo , LFA Santos, AH Iglesias - Free Radical Biology , 2010 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0891584910003837 Atividade peroxidasica da enzima superoxido dismutase 1 humana: produaca§aca£o do radical carbonato, dimerizaaca§aca£o covalente da enzima e implicaaca§acaµes para a esclerose DB Medinas - 2010 - teses.usp.brhttps://www.teses.usp.br/teses/disponiveis/46/46131/tde-26042010-102014/en.php

Peptide H-VYLKTNVFL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-VYLKTNVFL-OH include the following: UBASH3A deficiency accelerates type 1 diabetes development and enhances salivary gland inflammation in NOD mice YG Chen , AE Ciecko, S Khaja, M Grzybowski - Scientific reports, 2020 - nature.comhttps://www.nature.com/articles/s41598-020-68956-6 Maternal antibiotic treatment protects offspring from diabetes development in nonobese diabetic mice by generation of tolerogenic APCs Y Hu, J Peng, N Tai, C Hu, X Zhang - The Journal of , 2015 - journals.aai.orghttps://journals.aai.org/jimmunol/article/195/9/4176/105082 T Cells Recognizing a Peptide Contaminant Undetectable by Mass V Brezar, S Culina, T aca˜sterbye, F Guillonneau - 2011 - academia.eduhttps://www.academia.edu/download/79737295/T_Cells_Recognizing_a_Peptide_Contaminan20220128-1153-mmp14t.pdf Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia SM Lieberman , T Takaki, B Han - The Journal of , 2004 - journals.aai.orghttps://journals.aai.org/jimmunol/article/173/11/6727/2076 Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes SM Lieberman , AM Evans, B Han - Proceedings of the , 2003 - National Acad Scienceshttps://www.pnas.org/doi/abs/10.1073/pnas.0932778100 Rapid video-based deep learning of cognate versus non-cognate T cell-dendritic cell interactions PN Anandakumaran , AG Ayers , P Muranski - Scientific Reports, 2022 - nature.comhttps://www.nature.com/articles/s41598-021-04286-5 Gut microbiome in type 1 diabetes: A comprehensive review P Zheng, Z Li, Z Zhou - Diabetes/metabolism research and , 2018 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/dmrr.3043 Cytotoxic T-cells from T-cell receptor transgenic NOD8. 3 mice destroy beta-cells via the perforin and Fas pathways NL Dudek, HE Thomas, L Mariana, RM Sutherland - Diabetes, 2006 - Am Diabetes Assochttps://diabetesjournals.org/diabetes/article-abstract/55/9/2412/13249 In islet-specific glucose-6-phosphatase-related protein, the beta cell antigenic sequence that is targeted in diabetes is not responsible for the loss of JJ Shieh, CJ Pan, BC Mansfield, JY Chou - Diabetologia, 2005 - Springerhttps://link.springer.com/article/10.1007/s00125-005-1848-6 Measuring death of pancreatic beta cells in response to stress and cytotoxic T cells JA Wali , P Trivedi, TW Kay, HE Thomas - Stress Responses: Methods and , 2015 - Springerhttps://link.springer.com/protocol/10.1007/978-1-4939-2522-3_12 In Vivo Cytotoxicity of Insulin-Specific CD8+ T-Cells in HLA-A*0201 Transgenic NOD Mice I Jarchum, JC Baker, T Yamada, T Takaki - Diabetes, 2007 - Am Diabetes Assochttps://diabetesjournals.org/diabetes/article-abstract/56/10/2551/12781 Glucagon-reactive islet-infiltrating CD 8 T cells in NOD mice G Mukherjee , RJ Chaparro, J Schloss, C Smith - , 2015 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1111/imm.12415 The proteasome inhibitor bortezomib controls indoleamine 2, 3-dioxygenase 1 breakdown and restores immune regulation in autoimmune diabetes G Mondanelli , E Albini, MT Pallotta, C Volpi - Frontiers in , 2017 - frontiersin.orghttps://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2017.00428/full Islet antigen-pulsed dendritic cells expressing ectopic IL-35Ig protect nonobese diabetic mice from autoimmune diabetes G Mondanelli , C Volpi , R Bianchi , M Allegrucci - Cytokine, 2015 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S1043466615001726 Adoptive transfer of autoimmune diabetes using immunodeficient nonobese diabetic (NOD) mice E De Leenheer , FS Wong - Type-1 Diabetes: Methods and Protocols, 2016 - Springerhttps://link.springer.com/protocol/10.1007/7651_2015_294 Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cells D Samanta , G Mukherjee - Proceedings of the , 2011 - National Acad Scienceshttps://www.pnas.org/doi/abs/10.1073/pnas.1110971108 Identification of a beta-cell-specific HLA class I restricted epitope in type 1 diabetes C Panagiotopoulos , H Qin, R Tan , CB Verchere - Diabetes, 2003 - Am Diabetes Assochttps://diabetesjournals.org/diabetes/article-abstract/52/11/2647/12768 Assessment of immunosuppressive activity of human mesenchymal stem cells using murine antigen specific CD4 and CD8 T cells in vitro C Nazarov, JL Surdo, SR Bauer, CH Wei - Stem cell research & therapy, 2013 - Springerhttps://link.springer.com/article/10.1186/scrt339 IL-21 regulates SOCS1 expression in autoreactive CD8+ T cells but is not required for acquisition of CTL activity in the islets of non-obese diabetic mice APR Sutherland , KL Graham, M Papadimitriou - Scientific Reports, 2019 - nature.comhttps://www.nature.com/articles/s41598-019-51636-5

Peptide H-FLYGALLLA-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-FLYGALLLA-OH include the following: Antigen-specific and cross-reactive T cells in protection and disease N Jiang , M Malone , S Chizari - Immunological reviews, 2023 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1111/imr.13217

Potent α1β1 integrin inhibitor, 0.8 nM IC50 for IV collagen binding. Selective over other integrins. Inhibits FGF2 angiogenesis; antitumor in mouse models.

Peptide H-GSENLKSLYN-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-GSENLKSLYN-OH include the following: Novel simian immunodeficiency virus CTL epitopes restricted by MHC class I molecule Mamu-B* 01 are highly conserved for long term in DNA/MVA-vaccinated, SHIV J Su, MA Luscher, Y Xiong, T Rustam - International , 2005 - academic.oup.comhttps://academic.oup.com/intimm/article-abstract/17/5/637/741834

A synthetic peptide for use as a blocking control in assays to test for specificity of ATG10 antibody, catalog no. 70R-3584

Peptide H-LAAIAESGVER-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-LAAIAESGVER-OH include the following: A semi-automated workflow for DIA-based global discovery to pathway-driven PRM analysis J Guergues, J Wohlfahrt, J Koomen , J Krieger - Authorea , 2024 - essopenarchive.orghttps://essopenarchive.org/doi/full/10.22541/au.171715674.40099264

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Boc-Dap-OtBu hydrochloride salt is a chemical that is synthesized by anhydride and trifluoroacetic acid. It can be used in the laboratory for protein visualization, as well as to detect proteins using LC-MS. The presence of trifluoroacetic acid makes the Boc-Dap-OtBu hydrochloride salt fluorescent, which makes it possible to visualize the reaction products under UV light. This chemical is often used in fluorescence spectrometry to identify amino acids and other compounds.

Peptide H-WKFDSRLAF-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-WKFDSRLAF-OH include the following: Enhanced detection of human immunodeficiency virus type 1 (HIV-1) Nef-specific T cells recognizing multiple variants in early HIV-1 infection U Malhotra, F Li, J Nolin, M Allison, H Zhao - Journal of , 2007 - Am Soc Microbiolhttps://journals.asm.org/doi/abs/10.1128/jvi.02564-06 High-avidity, high-IFNγ-producing CD8 T-cell responses following immune selection during HIV-1 infection NM Keane , SG Roberts, CAM Almeida - Immunology and cell , 2012 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1038/icb.2011.34

Peptide Ac-TVDRAEVPPLFWKPC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using Ac-TVDRAEVPPLFWKPC-NH2 include the following: Expression of membrane progesterone receptors on human T lymphocytes and Jurkat cells and activation of G-proteins by progesterone C Dosiou , AE Hamilton, Y Pang - Journal of , 2008 - academia.eduhttps://www.academia.edu/download/70922651/Expression_of_membrane_progesterone_rece20211001-21267-15ovxsd.pdf

A synthetic peptide for use as a blocking control in assays to test for specificity of INPP5K antibody, catalog no. 70R-10254

Flagellin is the structural protein which forms the major portion of bacterial flagella filaments. The N- and C- terminals of flagellin are highly conserved regions, whereas the central core can vary greatly between bacterial species. Flagellin 22 (flg22) is the most conserved stretch of amino acids across bacterial species and is located towards the N-terminal of flagellin.Flg22 is a potent elicitor of plant immune responses and is recognised in plants by the membrane bound leucine-rich repeat-receptor kinase FLAGELLIN SENSITIVE 2 (FLS2). Flg22 induces defence gene expression to trigger both local and systemic immune responses and is thus widely used in plant defence studies.Truncated flagellin 22 (flg22-θ”2) represents amino acids 1-20 of flg22. It is a strong and selective agonist of tomato FLS2, with weak agonist activity towards Arabidopsis FLS2 even at high concentrations.

A synthetic peptide for use as a blocking control in assays to test for specificity of EXOC6 antibody, catalog no. 70R-3769

Peptide H-WHWLQLKPGQPMY-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-WHWLQLKPGQPMY-OH include the following: Position one analogs of the Saccharomyces cerevisiae tridecapeptide pheromone YL Zhang, HUIFEN LU, JM Becker - The Journal of peptide , 1997 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1111/j.1399-3011.1997.tb01190.x Synthesis, Biological Activity, and Conformational Analysis of Peptidomimetic Analogues of the Saccharomyces cerevisiae alpha-Factor Tridecapeptide YL Zhang, HR Marepalli, H Lu, JM Becker - Biochemistry, 1998 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/bi980787u Receptor in Saccharomyces cereuisiae SK RathsSQ, M BeckerSII - researchgate.nethttps://www.researchgate.net/profile/Jeffrey-Becker-2/publication/20308809_Peptide_analogs_compete_with_binding_of_-factor_to_its_receptor_in_Saccharomyces_cerevisiae/links/09e415111549c85414000000/Peptide-analogs-compete-with-binding-of-factor-to-its-receptor-in-Saccharomyces-cerevisiae.pdf Peptide analogues compete with the binding of alpha-factor to its receptor in Saccharomyces cerevisiae. SK Raths, F Naider, JM Becker - Journal of Biological Chemistry, 1988 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0021925819778405 Binding of fluorinated phenylalanine alpha-factor analogues to ste2p: Evidence for a cation-Ï€ binding interaction between a peptide ligand and its cognate G protein S Tantry, FX Ding, M Dumont , JM Becker, F Naider - Biochemistry, 2010 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/bi100280f Position 13 analogs of the tridecapeptide mating pheromone from Saccharomyces cerevisiae: design of an iodinatable ligand for receptor binding S Liu, B Arshava, F Naider, LK Henry - Journal of Peptide , 2000 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1034/j.1399-3011.2000.00730.x Ab initio calculations on Pro-Ala and Pro-Gly dipeptides O Antohi, F Naider, AM Sapse - Journal of Molecular Structure , 1996 - Elsevierhttps://www.sciencedirect.com/science/article/pii/0166128095043608 Structural requirement tryptophan1,3 of tridecapeptide mating pheromone of Saccharomyces cerevisiae NJ Hong, YA Park, JW Lee - : Proceedings of the 1st International Peptide , 2002 - Springerhttps://link.springer.com/content/pdf/10.1007/0-306-46864-6_157.pdf Studies on conformational consequences of i to i+ 3 side-chain cyclization in model cyclic tetrapeptides MH RAO, WEI YANG, H JOSHUA - Journal of Peptide , 1995 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1111/j.1399-3011.1995.tb01057.x Specificity characterization of the alpha-mating factor hormone by Kex2 protease MA Manfredi, AA Antunes, LOP Jesus, MA Juliano - Biochimie, 2016 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0300908416302358 Control of the yeast cell cycle with a photocleavable alpha-factor analogue LL Parker , JW Kurutz, SBH Kent - Chemie (International ed , 2006 - ncbi.nlm.nih.govhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788609/ Matrix-assisted laser desorption/ionization mass spectrometry peptide sequencing utilizing selective N-terminal bromoacetylation J Song, HJ Kim - Analytical biochemistry, 2012 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0003269711007548 Solution Structures of i to i + 3 Cyclized Model Peptides: Building Blocks Mimicking Specific Conformations HR Marepalli, O Antohi, JM Becker - Journal of the American , 1996 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ja954217i Highly active analogs of alpha-factor and their activities against Saccharomyces cerevisiae HJ Ahn, EY Hong, DH Jin, NJ Hong - Bulletin of the Korean Chemical , 2014 - Citeseerhttps://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&doi=509ee315e2cbcb9fac108f48dfb1fa89d076f1b2 Identification of residue-to-residue contact between a peptide ligand and its G protein-coupled receptor using periodate-mediated dihydroxyphenylalanine cross GKE Umanah, L Huang , F Ding, B Arshava - Journal of biological , 2010 - ASBMBhttps://www.jbc.org/article/S0021-9258(20)60639-1/abstract Cross-linking of a DOPA-containing peptide ligand into its G protein-coupled receptor GKE Umanah, C Son , FX Ding, F Naider - Biochemistry, 2009 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/bi802061z Structural requirements for alpha-mating factor activity G Houen, O Nielsen, C Flanagan - FEBS letters, 1996 - Elsevierhttps://www.sciencedirect.com/science/article/pii/0014579396007260 The alpha-factor mating pheromone of Saccharomyces cerevisiae: a model for studying the interaction of peptide hormones and G protein-coupled receptors F Naider, JM Becker - Peptides, 2004 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0196978104002943 Studies on the yeast alpha-mating factor: A model for mammalian peptide hormones F Naider, J Gounarides, CB Xue - Biopolymers , 1992 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/bip.360320407 Probing the Binding Site of a Heptahelical Peptide Pheromone Receptor Using Photoaffinity Labelling, Site-Directed Mutagenesis and Spectroscopic Approaches F Naider, BK Lee, LK Henry, F Ding, SK Khare - Peptides: The Wave of , 2001 - Springerhttps://link.springer.com/chapter/10.1007/978-94-010-0464-0_409 Biophysical studies on a transmembrane peptide of the Saccharomyces cerevisiae alpha-factor receptor F Naider, B Arshava, H Xie, S Liu, WY Eng - Peptides for the New , 2002 - Springerhttps://link.springer.com/content/pdf/10.1007/0-306-46881-6_151.pdf Characterization of novel peptide agonists of the alpha mating factor of Saccharomyces cerevisiae EG Siegel, R Gunther, H Schafer, UR Fölsch - Analytical , 1999 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0003269799942896 Antagonistic and synergistic peptide analogs of the tridecapeptide mating pheromone of Saccharomyces cerevisiae E Eriotou-Bargiota , CB Xue, F Naider, JM Becker - Biochemistry, 1992 - ACS Publicationshttps://pubs.acs.org/doi/pdf/10.1021/bi00117a036 Probing the functional conformation of the tridecapeptide mating pheromone of Saccharomyces cerevisiae through study of disulfide-constrained analogs CHUB XUE, A MCKINNEY, HUIFEN LU - journal of peptide , 1996 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1111/j.1399-3011.1996.tb01336.x Spiegel, zyxwvutsrqponm B Molitoris, AC Alfrey, RA Harris, FR Simon - Am. J. Physiol, 1985 - academia.eduhttps://www.academia.edu/download/41221846/Antagonistic_and_synergistic_peptide_ana20160115-15517-198v4vt.pdf Long-distance rotational echo double resonance measurements for the determination of secondary structure and conformational heterogeneity in peptides B Arshava, M Breslav, O Antohi, RE Stark - Solid State Nuclear , 1999 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0926204099000181 Synthesis of biologically active analogs of the dodecapeptide alpha-factor mating pheromone of Saccharomyces cerevisiae A EWENSON, S MARCUS - Journal of Peptide , 1990 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1111/j.1399-3011.1990.tb00944.x

Peptide H-Myr-GSNKSKPK-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-Myr-GSNKSKPK-NH2 include the following: Inhibition of N-myristoyltransferase activity promotes androgen receptor degradation in prostate cancer OA Alsaidan , E Onobun , C Ye, L Lou , Z Beharry - The ..., 2024 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/pros.24645 Extracellular vesicles: The next generation of biomarkers and treatment for central nervous system diseases G Zanirati, PG Dos Santos, AM Alcará, F Bruzzo- International Journal of ..., 2024 - mdpi.comhttps://www.mdpi.com/1422-0067/25/13/7371 Engineering extracellular vesicles to deliver CRISPR ribonucleoprotein for gene editing JA Whitley , H Cai - Journal of Extracellular Vesicles, 2023 - Wiley Online Libraryhttps://isevjournals.onlinelibrary.wiley.com/doi/abs/10.1002/jev2.12343 Encapsulating Cas9 into extracellular vesicles by protein myristoylation JA Whitley , S Kim, L Lou , C Ye- Journal of ..., 2022 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/jev2.12196 BFSP1 C-terminal domains released by post-translational processing events can alter significantly the calcium regulation of AQP0 water permeability A Tapodi , DM Clemens , A Uwineza , M Jarrin- Experimental eye ..., 2019 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0014483518307395

ALX40-4C is a small peptide inhibitor of the chemokine receptor CXCR4 that can inhibit X4 strains of HIV-1.

A synthetic peptide for use as a blocking control in assays to test for specificity of C18orf32 antibody, catalog no. 70R-4308

Peptide H-KLCEGGCIGCGACGGW-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-KLCEGGCIGCGACGGW-OH include the following: Frequency-switching inversion-recovery for severely hyperfine-shifted NMR: evidence of asymmetric electron relaxation in high-spin Co (II) EA Riley, AK Petros , KA Smith, BR Gibney - Inorganic , 2006 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ic061207h Peptide-based FeS 4 complexes: the zinc ribbon fold is unsurpassed to stabilize both the Fe II and Fe III states A Jacques, JM Latour, O Senacašque - Dalton Transactions, 2014 - pubs.rsc.orghttps://pubs.rsc.org/en/content/articlehtml/2014/dt/c3dt53157k

Catalogue peptide; min. 95% purity

Peptide H-DSSTSPGDYVLSVSENSR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-DSSTSPGDYVLSVSENSR-OH include the following: Interrogating the human genome using uninterpreted mass spectrometry data JS Choudhary , WP Blackstock - PROTEOMICS , 2001 - Wiley Online Libraryhttps://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/1615-9861(200104)1:5%3C651::AID-PROT651%3E3.0.CO;2-N

Peptide H-QGINNLDNL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-QGINNLDNL-OH include the following: Effect of TAP on the generation and intracellular trafficking of peptide-receptive major histocompatibility complex class I molecules PM Day, F Esquivel , J Lukszo, JR Bennink, JW Yewdell - Immunity, 1995 - cell.comhttps://www.cell.com/immunity/pdf/S1074-7613(95)80014-X.pdf Inefficient cross-presentation limits the CD8+ T cell response to a subdominant tumor antigen epitope P Otahal, SC Hutchinson, LM Mylin - The Journal of , 2005 - journals.aai.orghttps://journals.aai.org/jimmunol/article/175/2/700/36672 Avoiding tolerance against prostatic antigens with subdominant peptide epitopes ME Grossmann, E Davila, E Celis - Journal of Immunotherapy, 2001 - journals.lww.comhttps://journals.lww.com/immunotherapy-journal/fulltext/2001/05000/Avoiding_Tolerance_Against_Prostatic_Antigens_With.7.aspx Hierarchy among multiple H-2b-restricted cytotoxic T-lymphocyte epitopes within simian virus 40 T antigen LM Mylin, RH Bonneau, JD Lippolis - Journal of virology, 1995 - Am Soc Microbiolhttps://journals.asm.org/doi/abs/10.1128/jvi.69.11.6665-6677.1995 Functional analysis of amino acid residues encompassing and surrounding two neighboring H-2Db-restricted cytotoxic T-lymphocyte epitopes in simian virus 40 tumor JD Lippolis , LM Mylin, DT Simmons - Journal of virology, 1995 - Am Soc Microbiolhttps://journals.asm.org/doi/abs/10.1128/jvi.69.5.3134-3146.1995 CD8+ T-cell cross-competition is governed by peptide-MHC class I stability I Galea , J Stasakova, MS Dunscombe - European journal of , 2012 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/eji.201142010 Accumulation of CD8+ T cells in advanced-stage tumors and delay of disease progression following secondary immunization against an immunorecessive epitope CM Ryan, TD Schell - The Journal of Immunology, 2006 - journals.aai.orghttps://journals.aai.org/jimmunol/article/177/1/255/37624 Combined anti-CD40 conditioning and well-timed immunization prolongs CD8+ T cell accumulation and control of established brain tumors CM Ryan, K Staveley-O'Carroll - Journal of , 2008 - journals.lww.comhttps://journals.lww.com/immunotherapy-journal/FullText/2008/11000/Combined_Anti_CD40_Conditioning_and_Well_timed.12.aspx Direct presentation regulates the magnitude of the CD8+ T cell response to cell-associated antigen through prolonged T cell proliferation AM Tatum, AM Watson , TD Schell - The Journal of Immunology, 2010 - journals.aai.orghttps://journals.aai.org/jimmunol/article/185/5/2763/38858

A synthetic peptide for use as a blocking control in assays to test for specificity of ASNA1 antibody, catalog no. 70R-10010

Peptide H-GGVGKIIEYFIGGGVGRYG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-GGVGKIIEYFIGGGVGRYG-OH include the following: Yeast Peptides Improve the Intestinal Barrier Function and Alleviate Weaning Stress by Changing the Intestinal Microflora Structure of Weaned Lambs Y Li, L Han, J Liu, L Kang, L Zhao , K Cui - Microorganisms, 2023 - mdpi.comhttps://www.mdpi.com/2076-2607/11/10/2472 The Anti-Microbial Peptide Citrocin Controls Pseudomonas aeruginosa Biofilms by Breaking Down Extracellular Polysaccharide L Wang, J Zheng, W Hou, C Zhang, J Zhang - International Journal of , 2024 - mdpi.comhttps://www.mdpi.com/1422-0067/25/7/4122

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Peptide H-LGADMEDV^R-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-LGADMEDV^R-OH include the following: A high throughput, multiplexed and targeted proteomic CSF assay to quantify neurodegenerative biomarkers and apolipoprotein E isoforms status WE Heywood , A Baud, E Bliss, E Sirka - JoVE (Journal of , 2016 - jove.comhttps://www.jove.com/t/54541/a-high-throughput-multiplexed-targeted-proteomic-csf-assay-to Kinetics of plasma apolipoprotein E isoforms by LC-MS/MS: a pilot study V Blanchard , S Ramin-Mangata - Journal of Lipid , 2018 - ASBMBhttps://www.jlr.org/article/S0022-2275(20)33124-2/fulltext isoform by targeted mass spectrometry across a clinical cohort (n= 800): a case study for SRM-based assay validation and methionine-containing proteotypic peptide R Simon, C Fonbonne, JC Lambert - Congracašs franacahttps://hal.science/hal-00960636/ Plasma proteome profiling to assess human health and disease PE Geyer , NA Kulak , G Pichler , LM Holdt, D Teupser - Cell systems, 2016 - cell.comhttps://www.cell.com/fulltext/S2405-4712(16)30072-2 The role of apolipoprotein E in neurodegeneration and cardiovascular disease MF Lopez, B Krastins, MM Ning - Expert review of proteomics, 2014 - Taylor & Francishttps://www.tandfonline.com/doi/abs/10.1586/14789450.2014.901892 15N-Labeled Full-Length Apolipoprotein E4 as an Internal Standard for Mass Spectrometry Quantification of Apolipoprotein E Isoforms M Wang, J Chen, IV Turko - Analytical chemistry, 2012 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ac3018873 Mass spectrometry quantification revealed accumulation of C-terminal fragment of apolipoprotein E in the Alzheimer's frontal cortex M Wang, IV Turko - PloS one, 2013 - journals.plos.orghttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0061498 Quantitation of 87 proteins by nLC-MRM/MS in human plasma: workflow for large-scale analysis of biobank samples M Rezeli , K Sjödin, H Lindberg - Journal of proteome , 2017 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acs.jproteome.7b00235 Quantification of total apolipoprotein E and its specific isoforms in cerebrospinal fluid and blood in Alzheimer's disease and other neurodegenerative diseases M Rezeli , H Zetterberg , K Blennow, A Brinkmalm - EuPA Open , 2015 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S2212968515300143 EuPA Open Proteomics M Rezeli , H Zetterberg , K Blennow, A Brinkmalm - cyberleninka.orghttps://cyberleninka.org/article/n/135520.pdf Human apolipoprotein e resequencing by proteomic analysis and its application to serotyping M Nishimura, M Satoh , S Nishimura, S Kakinuma - Plos one, 2014 - journals.plos.orghttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085356 Human Apolipoprotein E Resequencing by Proteomic Analysis and Its Application M Nishimura , M Satoh , S Nishimura, S Kakinuma - 2014 - academia.eduhttps://www.academia.edu/download/53350102/Human_Apolipoprotein_E_Resequencing_by_P20170531-28951-1anyn57.pdf APOE4 Copy Number-Dependent Proteomic Changes in the Cerebrospinal Fluid 1 M Berger , M Cooter, AS Roesler - Journal of , 2021 - content.iospress.comhttps://content.iospress.com/articles/journal-of-alzheimers-disease/jad200747 Unbiased Detection of Cysteine Sulfenic Acid by 473 nm Photodissociation Mass Spectrometry: Toward Facile In Vivo Oxidative Status of Plasma Proteins JV Guillaubez, D Pitrat, Y Bretonniacašre - Analytical , 2021 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acs.analchem.0c04484 Advantageous uses of mass spectrometry for the quantification of proteins JE Hale - International journal of proteomics, 2013 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1155/2013/219452 Automated multiplex LC-MS/MS assay for quantifying serum apolipoproteins AI, B, CI, C-II, C-III, and E with qualitative apolipoprotein e phenotyping I van den Broek, FP Romijn, J Nouta - Clinical , 2016 - academic.oup.comhttps://academic.oup.com/clinchem/article-abstract/62/1/188/5611795 Assessment of peptide chemical modifications on the development of an accurate and precise multiplex selected reaction monitoring assay for apolipoprotein e E Martenez-Morillo , HM Nielsen, I Batruch - Journal of proteome , 2014 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/pr401060x New plasma LC-MS/MS assays for the quantitation of beta-amyloid peptides and identification of apolipoprotein E proteoforms for Alzheimer's disease risk DM Weber , JC Kim, SM Goldman - Journal of , 2023 - journals.sagepub.comhttps://journals.sagepub.com/doi/abs/10.1177/10815589241246537 Development of highly multiplex targeted proteomics assays in biofluids using the Stellar mass spectrometer DL Plubell, PM Remes , CC Wu, CC Jacob - bioRxiv, 2024 - biorxiv.orghttps://www.biorxiv.org/content/10.1101/2024.06.04.597431.abstract MSACL 2023 Abstract (s) for Proteomics D Qasrawi - msacl.orghttps://www.msacl.org/program/view_abstract_selection.php?topic=Proteomics&event=2023 Development of new quantitative mass spectrometry and semi-automatic isofocusing methods for the determination of Apolipoprotein E typing C Hirtz , J Vialaret , G Nouadje, S Schraen, P Benlian - Clinica Chimica , 2016 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0009898115300917 Erin E. Franklin2, 3, Fan Liao1, Hong Jiang1, David Holtzman1, 3, 4, Nigel J. Cairns1, 2, 3, 4, John C. Morris1, 3, 4, and Randall J. Bateman1, 3, 4 AT Baker-Nigh, KG Mawuenyega, JG Bollinger, V Ovod - 2016 - researchgate.nethttps://www.researchgate.net/profile/Vitaliy-Ovod/publication/309546365_Human_Central_Nervous_System_CNS_ApoE_Isoforms_Are_Increased_by_Age_Differentially_Altered_by_Amyloidosis_and_Relative_Amounts_Reversed_in_the_CNS_Compared_with_Plasma/links/5817b7e308aeffbed6c33e16/Human-Central-Nervous-System-CNS-ApoE-Isoforms-Are-Increased-by-Age-Differentially-Altered-by-Amyloidosis-and-Relative-Amounts-Reversed-in-the-CNS-Compared-with-Plasma.pdf Plasma apolipoprotein E levels in longitudinally followed patients with mild cognitive impairment and Alzheimer's disease A Giannisis, A Al-Grety, H Carlsson, K Patra - Alzheimer's research & , 2022 - Springerhttps://link.springer.com/article/10.1186/s13195-022-01058-9

A synthetic peptide for use as a blocking control in assays to test for specificity of H2AFY antibody, catalog no. 70R-2126

A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF680 antibody, catalog no. 70R-9009

Peptide H-SYEPLEDPGVK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-SYEPLEDPGVK-OH include the following: Identification of transaldolase as a novel serum biomarker for hepatocellular carcinoma metastasis using xenografted mouse model and clinic samples C Wang , K Guo, D Gao, X Kang, K Jiang, Y Li, L Sun - Cancer letters, 2011 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0304383511005283

A synthetic peptide for use as a blocking control in assays to test for specificity of KLHDC1 antibody, catalog no. 70R-2991

A synthetic peptide for use as a blocking control in assays to test for specificity of PEX26 antibody, catalog no. 70R-2862

A synthetic peptide for use as a blocking control in assays to test for specificity of NUDCD3 antibody, catalog no. 70R-3285

A synthetic peptide for use as a blocking control in assays to test for specificity of TSPYL6 antibody, catalog no. 70R-1995

Peptide Ac-RFGRFLRKILRFLKK-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using Ac-RFGRFLRKILRFLKK-NH2 include the following: DP1, a multifaceted synthetic peptide: Mechanism of action, activity and clinical potential M Maan , H Goyal, S Joshi , P Barman , S Sharma- Life Sciences, 2024 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S002432052400047X Lysozyme-enhanced cellulose nanofiber, chitosan, and graphene oxide multifunctional nanocomposite for potential burn wound healing applications M Adhikari, OM Atta , MS Kishta, M Maboruk- International Journal of ..., 2024 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0141813024064766 Synthetic peptide (DP1) functionalized graphene oxide: A biocompatible nanoformulation with broad-spectrum antibacterial and antibiofilm activity S Joshi , J Chadha , K Harjai , G Verma , A Saini - FlatChem, 2024 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S2452262724000205 In Vivo Acute Toxicity and Therapeutic Potential of a Synthetic Peptide, DP1 in a Staphylococcus aureus Infected Murine Wound Excision Model P Barman , C Sharma, S Joshi , S Sharma- Probiotics and ..., 2023 - Springerhttps://link.springer.com/article/10.1007/s12602-023-10176-1 Design and Evaluation of a Novel Anti-microbial Peptide from Cathelicidin-2: Selectively Active Against Acinetobacter baumannii F Fathi , M Ghobeh , FH Shirazi- Iranian Journal of ..., 2023 - ncbi.nlm.nih.govhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10909124/ Design, characterization and structure-function analysis of novel antimicrobial peptides based on the N-terminal CATH-2 fragment P Sharma , S Sharma , S Joshi , P Barman , A Bhatt - Scientific Reports, 2022 - nature.comhttps://www.nature.com/articles/s41598-022-16303-2

A synthetic peptide for use as a blocking control in assays to test for specificity of ACTL6A antibody, catalog no. 70R-3160

Peptide H-KRLFKEFLFSLRKY-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-KRLFKEFLFSLRKY-OH include the following: Peptide self-assembly is linked to antibacterial, but not antifungal, activity of histatin 5 derivatives L Schnaider , A Rosenberg, T Kreiser , S Kolusheva - Msphere, 2020 - Am Soc Microbiolhttps://journals.asm.org/doi/abs/10.1128/msphere.00021-20