Peptides

ω-Conotoxin CnVIIA, a 27-amino-acid neuropeptide toxin, serves as an N-type calcium current blocker [1].

Peptide H-VSPGAFTPLVK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-VSPGAFTPLVK-OH include the following: Periostin suppression induces decorin secretion leading to reduced breast cancer cell motility and invasion T Ishiba , M Nagahara, T Nakagawa, T Sato - Scientific reports, 2014 - nature.comhttps://www.nature.com/articles/srep07069

A synthetic peptide for use as a blocking control in assays to test for specificity of PSG3 antibody, catalog no. 70R-1279

Three GTP-binding protein alpha subunits stay membrane-bound post-activation and are cleaved by trypsin, releasing fragments; previously thought cytoplasmic.

A synthetic peptide for use as a blocking control in assays to test for specificity of CUTC antibody, catalog no. 70R-4342

Ac-Arg-Gly-Lys-MCA is a histone deacetylase inhibitor that belongs to the class of peptides. This drug has been shown to inhibit the activity of histone deacetylases and can be used for the treatment of diabetes. Ac-Arg-Gly-Lys-MCA is an enzyme substrate, which means it is not active when taken orally. It must be administered intravenously or intraperitoneally in order to be metabolized by enzymes in the body.

A synthetic peptide for use as a blocking control in assays to test for specificity of SPPL2B antibody, catalog no. 70R-6412

Peptide H-ENREILKEPVHGVYY-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-ENREILKEPVHGVYY-OH include the following: Identification of linear heparin-binding peptides derived from human respiratory syncytial virus fusion glycoprotein that inhibit infectivity RL Crim, SA Audet, SA Feldman, HS Mostowski - Journal of , 2007 - Am Soc Microbiolhttps://journals.asm.org/doi/abs/10.1128/jvi.01226-06

A synthetic peptide for use as a blocking control in assays to test for specificity of FLAD1 antibody, catalog no. 70R-2167

Peptide H-DMQL^G-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-DMQL^G-OH include the following: Mutation of glutamate 199 of the human C5a receptor defines a binding site for ligand distinct from the receptor N terminus PN Monk , MD Barker, LJ Partridge, JE Pease - Journal of Biological , 1995 - ASBMBhttps://www.jbc.org/article/S0021-9258(17)46886-4/abstract

NFAT blocker; reduces IL-12, IL-23, TNF, and NO in BMDMs; eases mouse colitis; prolongs grafts; cell-permeable.

A synthetic peptide for use as a blocking control in assays to test for specificity of C1orf174 antibody, catalog no. 70R-4285

Difelikefalin acetate (CR 845 acetate) is a peripherally restricted kappa opioid receptor agonist.

Neuropeptide Y (NPY) is a peptide involved in the gut-brain axis. Neurons express it in both the brain and the gut. However, expression is significantly increased upon nerve injury. NPY is the most abundant neuropeptide within the brain and is expressed by many neuronal systems, and several important pathways utilising NPY as a neurotransmitter have been identified. Mammalian NPY acts as a vasoconstrictor by affecting blood pressure around peripheral nerves, while it also acts on food intake and emotional regulation.The primary receptor subtypes on which NPY acts in the brain are the Y1 and Y2 receptors but also include Y4, Y5 and y6 (a human pseudogene). Y1 and Y2 increase blood pressure, Y1 and Y5 increase food intake, and Y2 and Y4 decrease food intake.NPY has been linked to psychiatric disorders such as anxiety and depression. Low levels of NPY have been observed in patients with major depressive disorder. Rodent models are used to understand better NPY and its receptors' role in emotional regulation.

Peptide 5TAMRA-R-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using 5TAMRA-R-OH include the following: Quantitative structure-activity relationship study of antioxidative peptide by using different sets of amino acids descriptors YW Li , B Li, J He, P Qian - Journal of Molecular Structure, 2011 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S002228601100384X Conjugation of a photosensitizer to an oligoarginine-based cell-penetrating peptide increases the efficacy of photodynamic therapy Y Choi , JR McCarthy, R Weissleder - ChemMedChem , 2006 - Wiley Online Libraryhttps://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cmdc.200500036 Role of peptide hydrophobicity in the mechanism of action of alpha-helical antimicrobial peptides Y Chen , MT Guarnieri , AI Vasil, ML Vasil - Antimicrobial agents , 2007 - Am Soc Microbiolhttps://journals.asm.org/doi/abs/10.1128/aac.00925-06 Peptide modifications differentially alter G protein-coupled receptor internalization and signaling bias V Made, S Babilon, N Jolly, L Wanka - Angewandte Chemie , 2014 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201403750 Systemic in vivo distribution of activatable cell penetrating peptides is superior to that of cell penetrating peptides TA Aguilera , ES Olson, MM Timmers, T Jiang - Integrative , 2009 - academic.oup.comhttps://academic.oup.com/ib/article-abstract/1/5-6/371/5211408 C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration T Teesalu , KN Sugahara - Proceedings of the , 2009 - National Acad Scienceshttps://www.pnas.org/doi/abs/10.1073/pnas.0908201106 Concomitant Occurrence of Peptide 310- and alpha-Helices Probed by NMR S Mammi, M Rainaldi, M Bellanda - Journal of the , 2000 - ACS Publicationshttps://pubs.acs.org/doi/full/10.1021/ja002710a Stearylated arginine-rich peptides: a new class of transfection systems S Futaki, W Ohashi, T Suzuki, M Niwa - Bioconjugate , 2001 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/bc015508l Arginine-rich peptides: an abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery S Futaki, T Suzuki, W Ohashi, T Yagami - Journal of Biological , 2001 - ASBMBhttps://www.jbc.org/article/S0021-9258(19)46333-3/abstract Translocation of branched-chain arginine peptides through cell membranes: flexibility in the spatial disposition of positive charges in membrane-permeable peptides S Futaki, I Nakase, T Suzuki, Zhang , Y Sugiura - Biochemistry, 2002 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/bi0256173 Cell-surface interactions on arginine-rich cell-penetrating peptides allow for multiplex modes of internalization S Futaki, I Nakase - Accounts of chemical research, 2017 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acs.accounts.7b00221 Arginine-rich peptides: potential for intracellular delivery of macromolecules and the mystery of the translocation mechanisms S Futaki - International journal of pharmaceutics, 2002 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S037851730200337X Arginine-rich cell penetrating peptides: Design, structure-activity, and applications to alter pre-mRNA splicing by steric-block oligonucleotides R Abes, A Arzumanov, H Moulton - European Peptide , 2008 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/psc.979 Exploring the sequence space for (tri-) peptide self-assembly to design and discover new hydrogels PWJM Frederix , GG Scott, YM Abul-Haija - Nature , 2015 - nature.comhttps://www.nature.com/articles/nchem.2122 Design, synthesis, and evaluation of amphiphilic cyclic and linear peptides composed of hydrophobic and positively-charged amino acids as antibacterial agents N Riahifard, S Mozaffari , T Aldakhil, F Nunez - Molecules, 2018 - mdpi.comhttps://www.mdpi.com/1420-3049/23/10/2722 Selective amino acid substitution reduces cytotoxicity of the antimicrobial peptide mastoparan LN Irazazabal, WF Porto , SM Ribeiro , S Casale - et Biophysica Acta (BBA , 2016 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0005273616302449 Synthesis and application of unprotected cyclic peptides as building blocks for peptide dendrimers L Zhang, JP Tam - Journal of the American Chemical Society, 1997 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ja9621105 Molecular transporters for peptides: delivery of a cardioprotective ϵPKC agonist peptide into cells and intact ischemic heart using a transport system, R7 L Chen, LR Wright, CH Chen, SF Oliver, PA Wender - Chemistry & biology, 2001 - cell.comhttps://www.cell.com/ccbio/pdf/S1074-5521(01)00076-X.pdf Antibacterial activities of ferrocenoyl-and cobaltocenium-peptide bioconjugates JT Chantson, MVV Falzacappa, S Crovella - Journal of , 2005 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0022328X05005243 Effects of cargo molecules on the cellular uptake of arginine-rich cell-penetrating peptides JR Maiolo, M Ferrer , EA Ottinger - Biochimica et Biophysica Acta (BBAhttps://www.sciencedirect.com/science/article/pii/S0005273605001094 Peptide synthesis using unprotected peptides through orthogonal coupling methods. JP Tam , YIAN Lu, CFA Liu - Proceedings of the , 1995 - National Acad Scienceshttps://www.pnas.org/doi/abs/10.1073/pnas.92.26.12485 ω-Amino acids in peptide design. Crystal structures and solution conformations of peptide helices containing a beta-alanyl-γ-aminobutyryl segment IL Karle, A Pramanik , A Banerjee - Journal of the , 1997 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ja970566w A helix-stabilized cell-penetrating peptide as an intracellular delivery tool H Yamashita, M Oba , T Misawa, M Tanaka - , 2016 - Wiley Online Libraryhttps://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cbic.201500468 Sequence-specific Ni (II)-dependent peptide bond hydrolysis for protein engineering: reaction conditions and molecular mechanism E Kopera, A Krezel , AM Protas, A Belczyk - Inorganic , 2010 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ic1005709 Neuroprotective peptides fused to arginine-rich cell penetrating peptides: Neuroprotective mechanism likely mediated by peptide endocytic properties BP Meloni , D Milani, AB Edwards , RS Anderton - Pharmacology & , 2015 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0163725815001175 Selective peptide bond hydrolysis of cysteine peptides in the presence of Ni (II) ions AM Protas, A Bonna , E Kopera, W Bal - Journal of inorganic biochemistry, 2011 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0162013410002175 Prediction of peptide retention at different HPLC conditions from multiple linear regression models , M MarszaÅ‚Å‚ , YV Heyden , R Kaliszan - Journal of Proteome , 2005 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/pr049780r

Peptide H-LNIDLLWSV^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-LNIDLLWSV^-OH include the following: Vagaries of the ELISpot assay: Specific detection of antigen responsive cells requires purified CD8+ T cells and MHC class I expressing antigen presenting cell lines YF Fuchs, GW Jainta, D Kuhn, C Wilhelm, M Weigelt - Clinical , 2015 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S1521661615000613 Early-versus late-onset type 1 diabetes: two different pathophysiological subtypes with implications for therapy WM Kuhtreiber, M Davis - and Immune-based , 2017 - books.google.comhttps://books.google.com/books?hl=en&lr=&id=6PiODwAAQBAJ&oi=fnd&pg=PA27&dq=(%22LNIDLLWSV%5E%22+OR+%22H-LNIDLLWSV-OH%22+OR+%22H-LNIDLLWSV%5E-OH%22+OR+%22LNIDLLWSV%22)+AND+peptide&ots=C70ie99trV&sig=WzURAJi5CBYs712JP1rpWtDaRmY Early-versus late-onset type 1 diabetes: two different pathophysiological subtypes with implications for therapy WM Kuhtreiber, M Davis - and Immune-based , 2017 - books.google.comhttps://books.google.com/books?hl=en&lr=&id=6PiODwAAQBAJ&oi=fnd&pg=PA27&dq=(%22LNIDLLWSV%5E%22+OR+%22H-LNIDLLWSV-OH%22+OR+%22H-LNIDLLWSV%5E-OH%22+OR+%22LNIDLLWSV%22)+AND+peptide&ots=C70ie99ulX&sig=WrEdarajDVkJ7L_W-9gvD5p35Yo Novel automated blood separations validate whole cell biomarkers DE Burger, L Wang, L Ban , Y Okubo, WM Kuhtreiber - PLoS , 2011 - journals.plos.orghttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022430

Peptide 5Fam-CRGDK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using 5Fam-CRGDK-OH include the following: Internalizing RGD, a great motif for targeted peptide and protein delivery: a review article Z Davoodi, F Shafiee - Drug Delivery and Translational Research, 2022 - Springerhttps://link.springer.com/article/10.1007/s13346-022-01116-7 Tumor-targeting peptide for redox-responsive Pt prodrug and gene codelivery and synergistic cancer chemotherapy Y Bai, Z Li, L Liu, T Sun, X Fan, T Wang - ACS Applied Bio , 2019 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acsabm.9b00065 Increased antitumor activity of tumor-specific peptide modified thymopentin X Lao, B Li, M Liu, J Chen, X Gao, H Zheng - Biochimie, 2014 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0300908414002624 Does ligand-receptor mediated competitive effect or penetrating effect of iRGD peptide when co-administration with iRGD-modified SSL? WQ Zhang, KF Yu, T Zhong , LM Luo, R Du - Journal of drug , 2015 - Taylor & Francishttps://www.tandfonline.com/doi/abs/10.3109/1061186X.2015.1034279 Peptide-functionalized delivery vehicles for enhanced cancer therapy SY Tang, H Wei, CY Yu - International Journal of Pharmaceutics, 2021 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0378517320311261 Peptide-mediated cancer targeting of nanoconjugates S Raha , T Paunesku - Wiley Interdisciplinary , 2011 - Wiley Online Libraryhttps://wires.onlinelibrary.wiley.com/doi/abs/10.1002/wnan.121 Neuropilin-1 Binding Peptide as Fusion to Diphtheria Toxin Induces Apoptosis in Non-small Cell Lung Cancer Cell Line S Eghtedari, M Behdani - Current , 2024 - ingentaconnect.comhttps://www.ingentaconnect.com/content/ben/cpd/2024/00000030/00000017/art00003 Developments in tumor targeting and internalizing peptides RIC Padanha - 2017 - repositorio.ul.pthttps://repositorio.ul.pt/handle/10451/36085 Peptide-based nanoprobes for molecular imaging and disease diagnostics P Zhang , Y Cui, CF Anderson , C Zhang, Y Li - Chemical Society , 2018 - pubs.rsc.orghttps://pubs.rsc.org/en/content/articlehtml/2018/cs/c7cs00793k Homing peptides for cancer therapy P Lingasamy , T Teesalu - Bio-nanomedicine for cancer therapy, 2021 - Springerhttps://link.springer.com/chapter/10.1007/978-3-030-58174-9_2 Tumor penetrating peptide-functionalized tenascin-C antibody for glioblastoma targeting P Lingasamy , AH Laarmann - Current cancer drug , 2021 - ingentaconnect.comhttps://www.ingentaconnect.com/content/ben/ccdt/2021/00000021/00000001/art00006 A versatile theranostic nanodevice based on an orthogonal bioconjugation strategy for efficient targeted treatment and monitoring of triple negative breast cancer MV Cano-Cortes , SA Navarro-Marchal - , Biology and Medicine, 2020 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S1549963419302047 Peptide-modified nanoparticles for tumor targeting and molecular imaging L Lu, Q Zhang, Z Wang, L Gao - Current Medicinal , 2021 - ingentaconnect.comhttps://www.ingentaconnect.com/content/ben/cmc/2021/00000028/00000031/art00009 De Novo Design of a Tumor-Penetrating Peptide L Alberici, L Roth, KN Sugahara, L Agemy - Cancer research, 2013 - AACRhttps://aacrjournals.org/cancerres/article-abstract/73/2/804/590737 Proapoptotic peptide-mediated cancer therapy targeted to cell surface p32 L Agemy, VR Kotamraju, D Friedmann-Morvinski - Molecular Therapy, 2013 - cell.comhttps://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(16)30945-5 Tissue-penetrating delivery of compounds and nanoparticles into tumors KN Sugahara, T Teesalu , PP Karmali, VR Kotamraju - Cancer cell, 2009 - cell.comhttps://www.cell.com/cancer-cell/pdf/S1535-6108(09)00382-1.pdf A tumor-penetrating peptide enhances circulation-independent targeting of peritoneal carcinomatosis KN Sugahara, P Scodeller , GB Braun - Journal of Controlled , 2015 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0168365915006161 Cell-Penetrating Peptide-Conjugated BF2-Oxasmaragdyrins as NIRF Imaging and Photothermal Agents K Laxman , BPK Reddy , A Robinson - , 2020 - Wiley Online Libraryhttps://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cmdc.202000401 Use of Chitosan from Southern King Crab to Develop Films Functionalized with RGD Peptides for Potential Tissue Engineering Applications JC Forero , K Carvajal, F Guzman, C Acevedo, N Osses - Biomimetics, 2023 - mdpi.comhttps://www.mdpi.com/2313-7673/8/3/323 Integrin-targeting peptides for the design of functional cell-responsive biomaterials J Zhao, F Santino, D Giacomini, L Gentilucci - Biomedicines, 2020 - mdpi.comhttps://www.mdpi.com/2227-9059/8/9/307 Theranostic iRGD peptide containing cisplatin prodrug: Dual-cargo tumor penetration for improved imaging and therapy HJ Cho , SJ Park, YS Lee , S Kim - Journal of controlled release, 2019 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0168365919301269 Activatable iRGD-based peptide monolith: Targeting, internalization, and fluorescence activation for precise tumor imaging HJ Cho , SJ Lee, SJ Park, CH Paik, SM Lee - Journal of Controlled , 2016 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0168365916304096 A free cysteine prolongs the half-life of a homing peptide and improves its tumor-penetrating activity HB Pang , GB Braun , ZG She , VR Kotamraju - Journal of Controlled , 2014 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0168365913009486 iRGD: a promising peptide for cancer imaging and a potential therapeutic agent for various cancers H Zuo - Journal of Oncology, 2019 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1155/2019/9367845 Peptide-decorated polymeric nanomedicines for precision cancer therapy H Sun , Y Dong, J Feijen , Z Zhong - Journal of controlled release, 2018 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0168365918305686 Acid-responsive PEGylated doxorubicin prodrug nanoparticles for neuropilin-1 receptor-mediated targeted drug delivery H Song, J Zhang, W Wang , P Huang, Y Zhang - Colloids and Surfaces B , 2015 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0927776515301995 Amphipathic tail-anchoring peptide is a promising therapeutic agent for prostate cancer treatment G De, JK Ko , T Tan, H Zhu , H Li , J Ma - Oncotarget, 2014 - ncbi.nlm.nih.govhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202157/ CRGDK-functionalized PAMAM-based drug-delivery system with high permeability D Liu, C Wang, J Yang, Y An, R Yang, G Teng - ACS omega, 2020 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acsomega.0c00202 Targeted modification of the cationic anticancer peptide HPRP-A1 with iRGD to improve specificity, penetration, and tumor-tissue accumulation C Hu, Y Huang, Y Chen - Molecular Pharmaceutics, 2018 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.8b00854 Nrp-1 receptor targeting peptide-functionalized TPGS micellar nanosystems to deliver 10-hydroxycampothecin for enhanced cancer chemotherapy A Mozhi , I Ahmad , QM Kaleem, RG Tuguntaev - International journal of , 2018 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0378517318303880 Gold nanoparticles functionalized with therapeutic and targeted peptides for cancer treatment A Kumar , H Ma, X Zhang , K Huang, S Jin , J Liu , T Wei - Biomaterials, 2012 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0142961211012622 Peptide-based strategies for targeted tumor treatment and imaging A Ayo, P Laakkonen - Pharmaceutics, 2021 - mdpi.comhttps://www.mdpi.com/1999-4923/13/4/481

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

vMIP-II (1-21) (NT21MP) TFA (TFA is a potent inhibitor of CXCR4. This compound interacts broadly with CC and CXC chemokine receptors. Furthermore, vMIP-II (1-21) TFA inhibits CXCR4 by competing for binding sites with 125I-SDF-1R, exhibiting an IC50 value of 190 nM.

Peptide H-QMVQQFK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-QMVQQFK-OH include the following: beta-1,3-Glucanase Activity in Peanut Seed (Arachis hypogaea) is Induced by Inoculation with Aspergillus flavus and Copurifies with a Conglutin-Like Protein XQ Liang, CC Holbrook, RE Lynch, BZ Guo - Phytopathology, 2005 - Am Phytopath Societyhttps://apsjournals.apsnet.org/doi/abs/10.1094/PHYTO-95-0506