Peptides

Fmoc-Thr[Ac4Galß(1- >3)Ac2GalNAcα(1->O)] -OH-O-ß-2,3,4,6-Tetra-O-Acetyl-D-Galactopyranosyl-(1- >3)-O-α-4,6-Di-O-Acetyl-2 -Acetamido -2 -Deoxy -D -Galactopyranosyl-(1->0)-9 Fluorenylmethoxycarbonyl L Thr Fmoc Thr is an amino acid that is used in peptide synthesis. It is a protected form of the amino acid threonine that can be cleaved by hydrogen fluoride to yield free Thr. Fmoc Thr has been shown to inhibit the production of inflammatory cytokines and chemokines in vitro.

A synthetic peptide for use as a blocking control in assays to test for specificity of TRPC3 antibody, catalog no. 70R-5179

Mean particle size: 75 µm. capacity: 0.4 - 0.6 mmol/g. This product can be used for the synthesis of peptides.

Peptide H-KGAIIGLMVGGVVIA-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-KGAIIGLMVGGVVIA-OH include the following: Destabilization of amyloid fibrils on interaction with MoS 2-based nanomaterials SK Mudedla , NA Murugan , V Subramanian , H Agren - RSC advances, 2019 - pubs.rsc.orghttps://pubs.rsc.org/en/content/articlehtml/2019/ra/c8ra10184a The PrecivityAD™test: Accurate and reliable LC-MS/MS assays for quantifying plasma amyloid beta 40 and 42 and apolipoprotein E proteotype for the KM Kirmess, MR Meyer, MS Holubasch, SS Knapik - Clinica Chimica , 2021 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0009898121001601 Amyloid-beta isoform metabolism quantitation by stable isotope-labeled kinetics KG Mawuenyega, T Kasten, W Sigurdson - Analytical , 2013 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0003269713002406 Interaction between U-shaped amyloid beta fibril and semiconducting silicon nitride monolayer A Shekaari - arXiv preprint arXiv:2403.10536, 2024 - arxiv.orghttps://arxiv.org/abs/2403.10536

Peptide H-VTEHDTLLY-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-VTEHDTLLY-NH2 include the following: Molecular pathogenesis of EBV susceptibility in XLP as revealed by analysis of female carriers with heterozygous expression of SAP U Palendira , C Low, A Chan, AD Hislop, E Ho - PLoS , 2011 - journals.plos.orghttps://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001187 Ex vivo functional analysis, expansion and adoptive transfer of cytomegalovirus-specific T-cells in patients with glioblastoma multiforme T Crough, L Beagley, C Smith , L Jones - Immunology and cell , 2012 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1038/icb.2012.19 Contemporaneous fluctuations in T cell responses to persistent herpes virus infections T Crough, JM Burrows, C Fazou - European journal of , 2005 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/eji.200425548 Identification and Characterization of Antigen-Specific T-Cells in Viral Infections SK Saini - Intracellular Pathogens - Springerhttps://link.springer.com/content/pdf/10.1007/978-1-0716-3890-3.pdf#page=297 Impaired direct priming of CD8 T cells by donor-derived cytomegalovirus following kidney transplantation S Shabir, B Kaul, A Pachnio, GD Banham - Journal of the , 2013 - journals.lww.comhttps://journals.lww.com/jasn/fulltext/2013/10000/impaired_direct_priming_of_cd8_t_cells_by.22.aspx Response to"Influence of Age and HLA Alleles on the CMV-Specific Cell-Mediated Immunity Among CMV-Seropositive Kidney Transplant Candidates" S Cantisan, R Solana - American Journal of , 2015 - amjtransplant.orghttps://www.amjtransplant.org/article/S1600-6135(22)00389-6/abstract Analytical performance of a standardized single-platform MHC tetramer assay for the identification and enumeration of CMV-specific CD8+ T lymphocytes RA Brooimans, CS Boyce, J Popma - Cytometry Part , 2008 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/cyto.a.20641 High-throughput T cell receptor engineering by functional screening identifies candidates with enhanced potency and specificity R Vazquez-Lombardi , JS Jung, FS Schlatter, A Mei - Immunity, 2022 - cell.comhttps://www.cell.com/immunity/pdf/S1074-7613(22)00498-8.pdf CRISPR-targeted display of functional T cell receptors enables engineering of enhanced specificity and prediction of cross-reactivity R Vazquez-Lombardi , JS Jung, F Bieberich - bioRxiv, 2020 - biorxiv.orghttps://www.biorxiv.org/content/10.1101/2020.06.23.166363.abstract Ex Vivo Profiling of CD8+-T-Cell Responses to Human Cytomegalovirus Reveals Broad and Multispecific Reactivities in Healthy Virus Carriers R Elkington, S Walker, T Crough, M Menzies - Journal of , 2003 - Am Soc Microbiolhttps://journals.asm.org/doi/abs/10.1128/jvi.77.9.5226-5240.2003 Antigen identification for HLA class I-and HLA class II-restricted T cell receptors using cytokine-capturing antigen-presenting cells MN Lee , M Meyerson - Science immunology, 2021 - science.orghttps://www.science.org/doi/abs/10.1126/sciimmunol.abf4001 Contribution of T cell receptor alpha and beta CDR3, MHC typing, V and J genes to peptide binding prediction I Springer, N Tickotsky, Y Louzoun - Frontiers in immunology, 2021 - frontiersin.orghttps://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2021.664514 Successful immunotherapy of HCMV disease using virus-specific T cells expanded from an allogeneic stem cell transplant recipient GR Hill, SK Tey , L Beagley, T Crough, JA Morton - American Journal of , 2010 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S1600613522195560 Identification and Characterization of Antigen-Specific T-Cells in Viral Infections D Trubach, KG Muleta, K Lahl , SK Saini - Intracellular Pathogens: Methods , 2024 - Springerhttps://link.springer.com/protocol/10.1007/978-1-0716-3890-3_19 Immunogenicity of human embryonic stem cell-derived beta cells CR van der Torren, A Zaldumbide, G Duinkerken - Diabetologia, 2017 - Springerhttps://link.springer.com/article/10.1007/s00125-016-4125-y Adoptive T-cell immunotherapy for ganciclovir-resistant CMV disease after lung transplantation CL Holmes-Liew, M Holmes, L Beagley - Clinical & , 2015 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1038/cti.2015.5 Sorting and pooling strategy: A novel tool to map a virus proteome for CD8 T-cell epitopes B Ay, M Streitz, P Boisguerin - Peptide Science , 2007 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/bip.20637 Using hydroxymethylphenoxy derivates with the SPOT technology to generate peptides with authentic C-termini B Ay, K Landgraf, M Streitz, S Fuhrmann - Bioorganic & medicinal , 2008 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0960894X08006355 Tonsillar homing of Epstein-Barr virus-specific CD8+ T cells and the virus-host balance AD Hislop, M Kuo, AB Drake-Lee - The Journal of , 2005 - Am Soc Clin Investighttps://www.jci.org/articles/view/24810 Thermal stability of heterotrimeric pMHC proteins as determined by circular dichroism spectroscopy A Fuller, A Wall, MD Crowther , A Lloyd, A Zhurov - Bio , 2017 - bio-protocol.orghttps://bio-protocol.org/pdf/Bio-protocol2366.pdf

A synthetic peptide for use as a blocking control in assays to test for specificity of FBXO4 antibody, catalog no. 70R-2792

Biotin-dPEG®4-TFP Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Biotin-dPEG®4-TFP Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Reactivity to human leukocyte antigens (HLAs) is a risen concern in clinical treatments such as organ transplant rejection. Understanding the epitopes causing reactivity and the signalling pathways could lead to better clinical therapies. The peptides presented by the non-classical HLA-G are important for a largely tolerogenic role and are considered part of an immune checkpoint. This, therefore, makes understanding ligand characteristics and HLA-G a target for cancer therapies. The HS1 fragment (160-168) has been identified as an epitope that human leukocyte antigen HLA-G naturally presents, determined by liquid chromatographic tandem mass spectrometry (LC-Ms/MS). This epitope has been used extensively in the literature to help understand the natural ligand presentation of HLA-G.For example, leukocyte immunoglobulin (Ig)-like receptors (LILRs) are key regulators of the immune response and therefore targets for therapeutics. Inhibitory LILRB1 and LILRB2 with HLA-G are pivotal for immunotolerance during pregnancy and autoimmune diseases plus cancer cell immune evasion. HS1 fragment (160-168) was used in binding affinity assays to clarify the conformational plasticity of the interaction between the receptor, the HLA antigen, and the various peptides HLA-G can accommodate.

A synthetic peptide for use as a blocking control in assays to test for specificity of Pde4d antibody, catalog no. 70R-9419

A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF780A antibody, catalog no. 70R-8883

A synthetic peptide for use as a blocking control in assays to test for specificity of SF3B14 antibody, catalog no. 70R-4706

Peptide Biot-AASHVDNEYSQPPRNSRLSAYPALE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using Biot-AASHVDNEYSQPPRNSRLSAYPALE-OH include the following: OX52 is the rat homologue of CD6: evidence for an effector function in the regulation of CD5 phosphorylation MAA Castro, RJ Nunes, MI Oliveira - Journal of Leucocyte , 2003 - academic.oup.comhttps://academic.oup.com/jleukbio/article-abstract/73/1/183/6979339 S100A4 regulates the Src-tyrosine kinase dependent differentiation of Th17 cells in rheumatoid arthritis M Brisslert , L Bian, MND Svensson , RF Santos - et Biophysica Acta (BBA , 2014 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0925443914002142

Anti GLP-1 (7-36)-NH₂, human serum is a recombinant protein that inhibits the activity of the glucagon-like peptide-1 receptor. It is used as a research tool to study the role of GLP-1 and its receptor in regulating blood glucose levels. Anti GLP-1 (7-36)-NH₂, human serum can be used as a ligand for the isolation of the GLP-1 receptor from cells. The anti GLP-1 (7-36)-NH₂, human serum is also used to study ion channels and antibody binding.

Peptide H-SDLVNEEATGQFR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-SDLVNEEATGQFR-OH include the following: Multiplexed targeted mass spectrometry assays for prostate cancer-associated urinary proteins T Shi , SI Quek , Y Gao , CD Nicora , S Nie , TL Fillmore - Oncotarget, 2017 - ncbi.nlm.nih.govhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731921/ Use of multiple reaction monitoring for multiplex analysis of colorectal cancer-associated proteins in human feces CS Ang , J Rothacker, H Patsiouras, P Gibbs - , 2011 - Wiley Online Libraryhttps://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/elps.201000502 Targeted Proteomics for Absolute Quantification of Protein Biomarkers in Serum and Tissues C Guzel, C Stingl, F Klont , R Tans - of Biomarkers and , 2019 - taylorfrancis.comhttps://www.taylorfrancis.com/chapters/edit/10.1201/9780429202872-48/targeted-proteomics-absolute-quantification-protein-biomarkers-serum-tissues-co%C5%9Fkun-g%C3%BCzel-christoph-stingl-frank-klont-roel-tans-esther-willems-rainer-bischoff-alain-van-gool-theo-luider Development of a Multimarker Urine Test for Prostate Cancer AY Liu - 2017 - apps.dtic.milhttps://apps.dtic.mil/sti/citations/AD1048555

Peptide H-FTVLTES^AAK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-FTVLTES^AAK^-OH include the following: Identification of site-specific stroke biomarker candidates by laser capture microdissection and labeled reference peptide T Lian, D Qu, X Zhao , L Yu, B Gao - International journal of molecular , 2015 - mdpi.comhttps://www.mdpi.com/1422-0067/16/6/13427 A map of neurofilament light chain species in brain and cerebrospinal fluid and alterations in Alzheimer's disease MM Budelier, Y He , NR Barthelemy , H Jiang - Brain , 2022 - academic.oup.comhttps://academic.oup.com/braincomms/article-abstract/4/2/fcac045/6534379 Glycosylation of Mammalian Neurofilaments LYD Dennis, R ChevrierII, J CotterJJ, W Cleveland - scholar.archive.orghttps://scholar.archive.org/work/snoqxi3aobdprnx7sylixqb2ii/access/wayback/http://cmm.ucsd.edu/cleveland/linked/dong_et_al__1993__j._biol._chem._268__16679-16687.pdf Glycosylation of mammalian neurofilaments. Localization of multiple O-linked N-acetylglucosamine moieties on neurofilament polypeptides L and M DL Dong, ZS Xu , MR Chevrier, RJ Cotter - Journal of Biological , 1993 - ASBMBhttps://www.jbc.org/article/S0021-9258(19)85471-6/abstract

Peptide H-SFGWDLAK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-SFGWDLAK-OH include the following: Standard-Free Absolute Quantitation of Antibody Deamidation Degradation and Host Cell Proteins by Coulometric Mass Spectrometry Y Ai , HP Gunawardena , X Li , YI Kim - Analytical , 2022 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acs.analchem.2c02709 Development of Novel Protein Digestion and Quantitation Methods for Mass Spectrometric Analysis Y Ai - 2023 - search.proquest.comhttps://search.proquest.com/openview/198379ce38281219995295aa8e5e346a/1?pq-origsite=gscholar&cbl=18750&diss=y

Catalogue peptide; min. 95% purity

A synthetic peptide for use as a blocking control in assays to test for specificity of CTF1 antibody, catalog no. 70R-5254