CAS 64-75-5: (-)-Clorhidrato de tetraciclina
Descripción:
(-)-Clorhidrato de tetraciclina es un antibiótico de amplio espectro que pertenece a la clase de las tetraciclinas, utilizado principalmente para tratar diversas infecciones bacterianas. Se caracteriza por su compleja estructura policíclica, que incluye cuatro anillos fusionados, lo que contribuye a su capacidad para inhibir la síntesis de proteínas en las bacterias al unirse a la subunidad ribosomal 30S. Este compuesto se presenta típicamente como una sal de clorhidrato, lo que mejora su solubilidad en agua. (-)-Clorhidrato de tetraciclina exhibe un color amarillo a naranja y es sensible a la luz, lo que puede llevar a su degradación. Es efectivo contra una amplia gama de bacterias grampositivas y gramnegativas, así como algunos protozoos. La sustancia también es conocida por sus propiedades antiinflamatorias y a veces se utiliza en el tratamiento del acné y otras afecciones cutáneas. Sin embargo, su uso puede provocar efectos secundarios, incluidos trastornos gastrointestinales y fotosensibilidad. Debido a su potencial para causar decoloración dental en niños, su uso generalmente se evita en mujeres embarazadas y niños pequeños. El almacenamiento adecuado alejado de la luz y la humedad es esencial para mantener su estabilidad y eficacia.
Fórmula:C22H24N2O8·ClH
InChI:InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
Clave InChI:InChIKey=XMEVHPAGJVLHIG-FMZCEJRJSA-N
SMILES:O[C@@]12[C@@](C[C@]3(C(=C1O)C(=O)C=4C([C@@]3(C)O)=CC=CC4O)[H])([C@H](N(C)C)C(O)=C(C(N)=O)C2=O)[H].Cl
Sinónimos:- (2E,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
- (2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aS,5aS,6S,12aS)-
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aS,5aS,6S,12aS)-
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5aα,6β,12aα)]-
- 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthalenecarboxamide hydrochloride
- 4-(Dimethylamino)-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide Hydrochloride (1:1)
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TETRACYCLINE HYDROCHLORIDE RS
CAS:TETRACYCLINE HYDROCHLORIDE RSFórmula:C22H25ClN2O8Peso molecular:480.8955Tetracycline hydrochloride (10mg/ml)
CAS:Tetracycline hydrochloride (10mg/ml)Forma y color:SolutionPeso molecular:494.92g/molTetracycline hydrochloride, Antibiotic for Culture Media Use Only
CAS:Tetracycline hydrochloride is a broad-spectrum antibiotic and is an electron transfer agent. It has been shown to be effective against bacterial infections in humans and has been used in cultures for the prevention of bacterial contamination. As an electron transfer agent, it is used in electron microscopy to study the surface of biological cells. Tetracycline hydrochloride enters bacterial cells by diffusion and interacts with the cytoplasmic membrane, where it induces a redox reaction that leads to cell death. The efficacy of tetracycline hydrochloride in treating candida albicans (yeast) was studied using in-vitro activity and showed that carboxymethyl chitosan nanoparticles were able to enhance the treatment efficiency.Fórmula:C22H25ClN2O8Pureza:Min. 88.0 Area-%Peso molecular:480.90 g/molRef: 3D-T-1961
1kgA consultar5kgA consultar10kgA consultar25kgA consultar2500gA consultar-Unit-kgkgA consultarTetracycline hydrochloride, USP grade
CAS:Fórmula:C22H24N2O8·HClForma y color:Yellow powderPeso molecular:480.91Tetracycline Hydrochloride
CAS:Tetracyclines and their derivatives; salts thereofFórmula:C22H24N2O8·ClHForma y color:Yellow PowderPeso molecular:480.12994Tetracycline Hydrochloride (TC), 95%
CAS:Fórmula:C22H24N2O8·HClPureza:min. 95%Forma y color:Yellow, Crystalline powderPeso molecular:480.90Tetracycline hydrochloride
CAS:Producto controladoFórmula:C22H24N2O8·ClHForma y color:NeatPeso molecular:480.90Tetracycline hydrochloride
CAS:Fórmula:C22H24N2O8·HClPureza:≥ 95.0%Forma y color:Yellow powderPeso molecular:480.91Tetracycline Hydrochloride
CAS:Applications Antibiotic substance produced by Streptomyces spp. Antiamebic; antibacterial; antirickettsial. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Weiss, et al.: Antibiot. Chemother., 7, 374 (1957), Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971),Fórmula:C22H24N2O8·ClHForma y color:NeatPeso molecular:480.90Tetracycline Hydrochloride
CAS:Fórmula:C22H24N2O8·HClPureza:>98.0%(T)Forma y color:Light yellow to Amber to Dark green powder to crystalPeso molecular:480.90Tetracycline hydrochloride
CAS:Antibiotic of tetracycline class; protein synthesis inhibitorFórmula:C22H25ClN2O8Forma y color:Yellow PowderPeso molecular:480.9 g/molTetracycline HCl (Oxytetracycline EP Impurity B HCl)
CAS:Fórmula:C22H24N2O8·HClForma y color:Pale Yellow SolidPeso molecular:444.45 36.46PharmaVetResiMix 5 Tetracyclines-v10 10 µg/mL in Methanol
CAS:Producto controladoForma y color:MixtureTetracycline hydrochloride - USP
CAS:Tetracycline hydrochloride - USP is a broad-spectrum antibiotic, which is a synthetic derivative of chlortetracycline produced from the bacterium *Streptomyces aureofaciens*. It functions by inhibiting protein synthesis in bacteria, specifically binding to the 30S ribosomal subunit. This action prevents the attachment of aminoacyl-tRNA to the mRNA-ribosome complex, thereby halting bacterial growth and replication. Tetracycline hydrochloride is primarily used in the treatment of various infections caused by susceptible strains of gram-positive and gram-negative bacteria, including respiratory tract infections, skin infections, and certain sexually transmitted diseases. Its broad-spectrum efficacy makes it a versatile agent for managing bacterial infections in both human and veterinary medicine. Additionally, it is utilized in research settings for studying bacterial protein synthesis and antibiotic resistance patterns.Fórmula:C22H25ClN2O8Forma y color:Yellow PowderPeso molecular:480.9 g/mol
