EGFR
Los inhibidores del receptor del factor de crecimiento epidérmico (EGFR) son compuestos que bloquean la señalización del EGFR, un receptor que a menudo está sobreexpresado en varios tipos de cáncer y que juega un papel crucial en la angiogénesis. Los inhibidores del EGFR se utilizan para prevenir el crecimiento tumoral y las metástasis al interrumpir las vías que promueven la formación de vasos sanguíneos en los tumores. Estos inhibidores son ampliamente utilizados en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia selección de inhibidores de EGFR de alta calidad para apoyar su investigación en oncología y angiogénesis.
Productos de "EGFR"
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AG-1478
CAS:AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.Fórmula:C16H14ClN3O2Pureza:99.03% - 99.71%Forma y color:SolidPeso molecular:315.75EGFR-IN-147
CAS:EGFR-IN-147 (compound ID-5841161) is a potent EGFR inhibitor, demonstrating a 14% inhibition rate at a concentration of 1μM. It holds promise for cancer research applications.Fórmula:C13H13N5OForma y color:SolidPeso molecular:255.275Neratinib
CAS:Fórmula:C30H29ClN6O3Pureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:557.05Tyrphostin A1
CAS:Fórmula:C11H8N2OPureza:>98.0%(GC)Forma y color:Light orange to Yellow to Green powder to crystalPeso molecular:184.20Lapatinib ditosylate monohydrate
CAS:Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.Fórmula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPureza:98% - 99.41%Forma y color:Colourless To Light-Yellow CrystalPeso molecular:943.47TX1-85-1
CAS:TX1-85-1: irreversible Her3 inhibitor (IC50: 23 nM), degrades Her3 protein, disrupts signaling, binds Cys721 covalently.Fórmula:C32H36N8O3Pureza:98.12% - 98.12%Forma y color:SolidPeso molecular:580.68WHI-P154
CAS:WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.Fórmula:C16H14BrN3O3Pureza:98% - 99.6%Forma y color:SolidPeso molecular:376.2Sapitinib
CAS:Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib orFórmula:C23H25ClFN5O3Pureza:98.89% - 99.83%Forma y color:SolidPeso molecular:473.93Alflutinib
CAS:Alflutinib (ASK120067) is an inhibitor of EGFR, and its targets including EGFR activating mutations and T790M, thus leading to tumor growth inhibition.Fórmula:C28H31F3N8O2Pureza:99.61%Forma y color:SolidPeso molecular:568.59Ref: TM-T22254
1mg213,00€5mg435,00€10mg620,00€25mg938,00€50mg1.320,00€100mg1.786,00€1mL*10mM (DMSO)560,00€EGFR-IN-128
EGFR-IN-128 (compound 28) is a potent and selective molecule targeting wild-type EGFREx20Ins, demonstrating therapeutic efficacy across various human xenograft models and capable of penetrating the blood-brain barrier in preclinical species.Fórmula:C27H20N4OForma y color:SolidPeso molecular:416.47Nezutatug
CAS:Nezutatug, an anti-HER3 antibody, serves as a research tool in cancer studies [1].Pureza:98%Forma y color:LiquidBPI-15086
CAS:BPI-15086 is an orally active, effective, irreversible inhibitor selective for mutations, targeting both EGFR and the T790M resistance mutation tyrosine kinase. It can be utilized in the study of non-small cell lung cancer.Fórmula:C29H33ClN8O4Forma y color:SolidPeso molecular:593.08FRF-06-057
FRF-06-057 is an allosteric ATP EGFR inhibitor targeting both wild-type and mutant EGFR, with IC50 values of 17 nM (LR/TM), 29 nM (LR/TM/CS), 220 nM (LR), and >1000 nM (WT).Fórmula:C19H13N3O3SForma y color:SolidPeso molecular:363.39Tyrphostin AG30
CAS:Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.Fórmula:C10H7NO4Pureza:99.02%Forma y color:SolidPeso molecular:205.17Labuxtinib
CAS:Labutinib is a selective inhibitor of the c-kit tyrosine kinase [1].Fórmula:C20H16FN5O2Pureza:99.77%Forma y color:SolidPeso molecular:377.37Ref: TM-T79851
1mg139,00€5mg338,00€10mg540,00€25mg1.074,00€50mg1.549,00€100mg2.080,00€200mg2.802,00€1mL*10mM (DMSO)374,00€Anti-EGFR Monoclonal Antibody-AF488
Anti-EGFR Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting EGFR. Anti-EGFR Monoclonal Antibody-AF488 can be used in FACS.Pureza:> 95% as determined by SDS-PAGE.Forma y color:LiquidPeso molecular:150 kDaDacomitinib
CAS:Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.Fórmula:C24H25ClFN5O2Pureza:100% - 99.72%Forma y color:SolidPeso molecular:469.94Ref: TM-T2483
1mg38,00€2mg49,00€5mg79,00€10mg127,00€25mg173,00€50mg227,00€100mg354,00€200mg444,00€500mg730,00€1mL*10mM (DMSO)79,00€Rezivertinib
CAS:Rezivertinib (BPI-7711) is an EGFR inhibitor with antitumor activity and can be used to study central nervous system diseases.Fórmula:C27H30N6O3Pureza:99.43% - 99.89%Forma y color:SolidPeso molecular:486.57Ref: TM-T36644
1mg99,00€5mg226,00€10mg364,00€25mg702,00€50mg947,00€100mg1.264,00€200mg1.700,00€1mL*10mM (DMSO)47,00€JH-XI-10-02
CAS:JH-XI-10-02 selectively degrades CDK8 (IC50: 159 nM) through proteasome, sparing CDK8 mRNA and CDK19.Fórmula:C53H69N5O9Pureza:98%Forma y color:SolidPeso molecular:920.161
