EGFR
Los inhibidores del receptor del factor de crecimiento epidérmico (EGFR) son compuestos que bloquean la señalización del EGFR, un receptor que a menudo está sobreexpresado en varios tipos de cáncer y que juega un papel crucial en la angiogénesis. Los inhibidores del EGFR se utilizan para prevenir el crecimiento tumoral y las metástasis al interrumpir las vías que promueven la formación de vasos sanguíneos en los tumores. Estos inhibidores son ampliamente utilizados en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia selección de inhibidores de EGFR de alta calidad para apoyar su investigación en oncología y angiogénesis.
Productos de "EGFR"
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EGFR/BRAFV600E-IN-2
E07 Aptamer, targeting the human epidermal growth factor receptor (hEGFR), competes with epidermal growth factor (EGF) for binding to a unique epitope on EGFR.Fórmula:C25H18N4O2Pureza:98%Forma y color:SolidPeso molecular:406.44BGB-8035
CAS:BGB-8035 is a BTK inhibitor with antitumor activity that inhibits BTK, TEC, and EGFR.BGB-8035 is used in the study of tumors and autoimmune diseases.Fórmula:C24H31N5O4Pureza:96.74%Forma y color:SolidPeso molecular:453.53Larotinib
CAS:Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.Fórmula:C24H26ClFN4O4Pureza:98.45%Forma y color:SolidPeso molecular:488.94BEBT-109
CAS:BEBT-109 is a selective epidermal growth factor receptor (EGFR) inhibitor that shows anti-tumor activity in EGFR-mutant non-small cell lung cancer.Fórmula:C27H32N8O3Pureza:99.01%Forma y color:SolidPeso molecular:516.6EGFR-IN-61
CAS:EGFR-IN-61 inhibits EGFR kinase (IC50: 42 nM L858R/T790M, 137 nM L858R/T790M/C797S, 743 nM WT) and slows A549 & H1975 cell growth (IC50: 2.14 & 1.82 μM).Fórmula:C33H37ClN8O3Pureza:98%Forma y color:SolidPeso molecular:629.15GW 583340
CAS:GW 583340 is a potent and selective dual inhibitor of EGFR/ErbB2 tyrosine kinase with the advantage of oral dosability and antitumor effects.Fórmula:C28H25ClFN5O3S2Pureza:98.68%Forma y color:SoildPeso molecular:598.11Ref: TM-T22827L
1mg185,00€5mg459,00€10mg657,00€25mg1.026,00€50mg1.415,00€100mg1.872,00€200mg2.555,00€Biochanin A
CAS:Biochanin A: an isoflavone from red clover with anticancer properties and inhibits FAAH.Fórmula:C16H12O5Pureza:97.1% - 98.97%Forma y color:SolidPeso molecular:284.26BKI-1369
CAS:BKI-1369 is a bumped kinase inhibitor. BKI-1369 increases hERG-inhibitory activity (IC50:1.52 μM).Fórmula:C23H27N7OForma y color:SolidPeso molecular:417.51Anti-EGFR Monoclonal Antibody-PE
Anti-EGFR Monoclonal Antibody-PE is a Biotin-conjugated rabbit antibody targeting EGFR. Anti-EGFR Monoclonal Antibody-PE can be used in FACS.Pureza:> 95% as determined by SDS-PAGE.Forma y color:LiquidPeso molecular:150 kDaPD 153035 Hydrochloride
CAS:Fórmula:C16H14BrN3O2·HClPureza:>97.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:396.67Calotatug ginistinag
CAS:Calotatug ginistinag (XMT-2056) is an antibody-drug conjugate (ADC) aimed at targeting HER2. It is connected by a linker (XMT-1519 conjugate-1) to an effective payload that includes a STING agonist (STING agonist-20), presenting potential in immune activation and anti-tumor activity.Forma y color:LiquidEGFR vIII Protein, Human, Recombinant (hFc)
EGFR vIII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.Forma y color:Lyophilized PowderPeso molecular:90-120 KDa (reducing condition)EGFR-IN-90
EGFR-IN-90 (compound 34), an orally active EGFR inhibitor, demonstrates potent activity against EGFRL858R/T790M/C797S with an IC50 of 5.1 nM and effectivelyPureza:98%Forma y color:Odour SolidEpertinib
CAS:Epertinib is a reversible and selective tyrosine kinase inhibitor of EGFR, HER2, and HER4 (IC50s: 1.48 nM, 7.15 nM, and 2.49 nM).Fórmula:C30H27ClFN5O3Pureza:98%Forma y color:SolidPeso molecular:560.02SU5204
CAS:SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) andFórmula:C17H15NO2Pureza:99.46%Forma y color:SolidPeso molecular:265.31PAT-505
CAS:PAT-505 is an autologous epidermal growth factor inhibitor.Fórmula:C23H18ClF2N3O2SPureza:98.84%Forma y color:SolidPeso molecular:473.92Tesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Fórmula:C24H25Cl2FN4O2Pureza:97.89% - 97.89%Forma y color:SolidPeso molecular:491.39Ref: TM-TQ0166
1mg107,00€2mg156,00€5mg236,00€10mg457,00€25mg750,00€50mg1.026,00€1mL*10mM (DMSO)255,00€NS-062
CAS:NS-062 is an orally effective, irreversible covalent inhibitor targeting EGFR, demonstrating antiproliferative activity in the resistant double mutant H1975 cells with an IC50 of 0.19 μM. It also exhibits antitumor activity in a murine H1975 xenograft model.Fórmula:C28H30Cl2F2N6O4Forma y color:SolidPeso molecular:623.48ZD-4190
CAS:ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.Fórmula:C19H16BrFN6O2Pureza:99.12%Forma y color:SolidPeso molecular:459.27Ref: TM-T5475
1mg85,00€5mg183,00€10mg275,00€25mg437,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)185,00€TAK-285
CAS:TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.Fórmula:C26H25ClF3N5O3Pureza:99.17%Forma y color:SolidPeso molecular:547.96
