EGFR
Los inhibidores del receptor del factor de crecimiento epidérmico (EGFR) son compuestos que bloquean la señalización del EGFR, un receptor que a menudo está sobreexpresado en varios tipos de cáncer y que juega un papel crucial en la angiogénesis. Los inhibidores del EGFR se utilizan para prevenir el crecimiento tumoral y las metástasis al interrumpir las vías que promueven la formación de vasos sanguíneos en los tumores. Estos inhibidores son ampliamente utilizados en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia selección de inhibidores de EGFR de alta calidad para apoyar su investigación en oncología y angiogénesis.
Productos de "EGFR"
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Depatuxizumab MMAF
Depatuxizumab-MMAF, an antibody-drug conjugate (ADC), comprises an EGFR-targeted antibody linked to McMMAF and is utilized in glioblastoma research.Forma y color:LiquidPeso molecular:148.24 kDaCP-724714
CAS:CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2Fórmula:C27H27N5O3Pureza:97.10% - 98.82%Forma y color:SolidPeso molecular:469.54Ref: TM-T4014
1mg44,00€2mg58,00€5mg95,00€10mg157,00€25mg273,00€50mg454,00€100mg660,00€1mL*10mM (DMSO)89,00€EAI001
CAS:EAI001 is a potent and selective mutant epidermal growth factor receptor (EGFR) variant inhibitor that inhibits EGFRL858R/T790M with an IC50 value of 24 nM.Fórmula:C19H15N3O2SPureza:100%Forma y color:SolidPeso molecular:349.41Lazertinib
CAS:Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.Fórmula:C30H34N8O3Pureza:98.7% - 99.53%Forma y color:SolidPeso molecular:554.64Self-assembling peptide pY1
Self-assembling peptide pY1, which aggregates around cancer cells, specifically targets the EGFR receptor. When co-cultured with Ovalbumin (OVA), pY1 effectively inhibits the endocytosis of OVA.Fórmula:C104H125N24O29PForma y color:SolidPeso molecular:2206.22EGFR Protein, Rhesus macaque, Recombinant (His)
EGFR Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag.Forma y color:Lyophilized PowderPeso molecular:69.8 kDa (predicted). Due to glycosylation, the protein migrates to 85-100 kDa based on Tris-Bis PAGE result.YS-363
CAS:YS-363 is a potent, selective, and orally active inhibitor of the epidermal growth factor receptor (EGFR), exhibiting half-maximal inhibitory concentrations (Fórmula:C30H30N4O3Pureza:98%Forma y color:SolidPeso molecular:494.58EGFR-IN-88
CAS:EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosisFórmula:C22H18Cl2N4O2SPureza:98%Forma y color:SolidPeso molecular:473.37JGK-068S
CAS:Compound I (JGK-068S) is a potent inhibitor of the epidermal growth factor receptor (EGFR) [1].Fórmula:C22H23BrFN5O2Pureza:98%Forma y color:SolidPeso molecular:488.35Tyrphostin AG 1478
CAS:Fórmula:C16H14ClN3O2Pureza:>98.0%(HPLC)Forma y color:Light orange to Yellow to Green powder to crystalPeso molecular:315.762H-1-Benzopyran-2-one, 7,8-dihydroxy-
CAS:Fórmula:C9H6O4Pureza:90%Forma y color:SolidPeso molecular:178.1415EGFR-IN-7
CAS:EGFR-IN-7 (TQB3804) is a selective and potent EGFR kinase inhibitor.Fórmula:C32H41BrN9O2PPureza:95.32% - 99.64%Forma y color:SolidPeso molecular:694.6Chalcone
CAS:Chalcone (Cinnamophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively asFórmula:C15H12OPureza:97.27%Forma y color:SolidPeso molecular:208.26Pelitinib
CAS:Fórmula:C24H23ClFN5O2Pureza:>97.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:467.93ZM39923 hydrochloride
CAS:ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Fórmula:C23H25NO·HClPureza:98.05%Forma y color:SolidPeso molecular:367.91Tesevatinib tosylate
CAS:Tesevatinib tosylate (XL-647 tosylate) is an orally administered epidermal growth factor receptor (EGFR) inhibitor that can cross the blood-brain barrier. It significantly reduces cell viability with IC50 values of 11 nM and 102 nM in GBM12 and GBM6, respectively. Additionally, Tesevatinib tosylate inhibits HER2 (IC50=16.1 nM), VEGFR2 (IC50=1.5 nM), and Src (IC50=10.3 nM), demonstrating antitumor activity by inhibiting tumor proliferation.Fórmula:C31H33Cl2FN4O5SForma y color:SolidPeso molecular:663.59EGFR-IN-5
CAS:EGFR-IN-5 inhibits EGFR & mutants; IC50: EGFR 10.4nM, L858R 1.1nM, L858R/T790M 34nM, L858R/T790M/C797S 7.2nM.Fórmula:C31H38FN9OPureza:98.17%Forma y color:SolidPeso molecular:571.69Intetumumab
CAS:Intetumumab (CNTO 95) is a fully humanized anti-α(v)-integrin monoclonal antibody that is a radiosensitizer for xenograft tumor-bearing mice.Forma y color:LiquidPeso molecular:145.6 (kDa)Desmethyl Erlotinib
CAS:Desmethyl Erlotinib (CP-473420) is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).Fórmula:C21H21N3O4Pureza:97.92% - 98.62%Forma y color:SolidPeso molecular:379.41Ref: TM-T6328
1mg52,00€2mg77,00€5mg115,00€10mg188,00€25mg331,00€50mg497,00€100mg720,00€1mL*10mM (DMSO)127,00€RTC-5
CAS:RTC-5 (TRC-382) is a phenothiazine compound that has been specifically enhanced for its potent anti-cancer properties.Fórmula:C24H22ClF3N2O3SPureza:98.14%Forma y color:SolidPeso molecular:510.96Ref: TM-T12777
5mg52,00€10mg80,00€25mg169,00€50mg284,00€100mg411,00€500mg867,00€1mL*10mM (DMSO)59,00€
