EGFR
Los inhibidores del receptor del factor de crecimiento epidérmico (EGFR) son compuestos que bloquean la señalización del EGFR, un receptor que a menudo está sobreexpresado en varios tipos de cáncer y que juega un papel crucial en la angiogénesis. Los inhibidores del EGFR se utilizan para prevenir el crecimiento tumoral y las metástasis al interrumpir las vías que promueven la formación de vasos sanguíneos en los tumores. Estos inhibidores son ampliamente utilizados en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia selección de inhibidores de EGFR de alta calidad para apoyar su investigación en oncología y angiogénesis.
Productos de "EGFR"
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EGFR/ErbB-2 inhibitor-1
CAS:EGFR/ErbB-2 inhibitor-1 is a selective ErbB2/HER2 inhibitor that effectively blocks ErbB2 and HER2 signaling.Fórmula:C23H15ClFN3OS2Pureza:97.55%Forma y color:SolidPeso molecular:467.97Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Fórmula:C9H6O4Pureza:97.47% - 99.8%Forma y color:SolidPeso molecular:178.14Calotatug
Calotatug is a humanized IgG1κ antibody targeting ERBB2, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Forma y color:Odour LiquidONO-7475
CAS:ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinaseFórmula:C32H26N4O6Pureza:98.74%Forma y color:SolidPeso molecular:562.57EGFR-IN-16
CAS:EGFR-IN-16 (AG473) is an inhibitor of EGFR in human A431 cells.Fórmula:C16H11NO3Pureza:98%Forma y color:SolidPeso molecular:265.26Tyrphostin A23
CAS:Fórmula:C10H6N2O2Pureza:>98.0%(GC)Forma y color:White to Light yellow powder to crystalPeso molecular:186.17Canertinib dihydrochloride
CAS:Canertinib dihydrochloride (PD-183805 dihydrochloride) is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic andFórmula:C24H27Cl3FN5O3Pureza:99.13% - 99.23%Forma y color:SolidPeso molecular:558.86CZC-8004
CAS:CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.Fórmula:C17H16FN5Pureza:99.29%Forma y color:SolidPeso molecular:309.34Lapatinib Ditosylate
CAS:Fórmula:C29H26ClFN4O4S·2C7H8O3SPureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:925.46Anti-EGFR Antibody (7X976)
Anti-EGFR Antibody (7X976) is an antibody targeting EGFR. Anti-EGFR Antibody (7X976) can be used in ELISA, WB, IHC, IF, FCM.Forma y color:Odour LiquidCurcumin (Natural)
CAS:Fórmula:C21H20O6Forma y color:Light yellow to Brown powder to crystalPeso molecular:368.39PF-06459988
CAS:PF-06459988 is a novel, effective, orally active, irreversible, and selective epidermal growth factor receptor (EGFR) mutant inhibitor.Fórmula:C19H22ClN7O3Pureza:98%Forma y color:SolidPeso molecular:431.88(E)-N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide；AG 490
CAS:Fórmula:C17H14N2O3Pureza:98%Forma y color:SolidPeso molecular:294.3047DS06652923
DS06652923 is an orally active inhibitor targeting EGFR triple mutations. It exhibits growth-inhibitory effects on Ba/F3EGFRdel19/T90M/C795S cells, with a GI50 value of 9.4 nM. Additionally, DS06652923 induces tumor regression in the Ba/F3 syngeneic transplantation model.Forma y color:Odour SolidDisitamab vedotin
CAS:Disitamab vedotin (RC-48) is a HER2-targeting ADC with MMAE, effective in HER2-expressing gastric cancer.Pureza:95.00% - 98%Forma y color:LiquidPeso molecular:Approximately 144.15 kDaNeratinib maleate
CAS:Neratinib maleate is a selective HER2/EGFR inhibitor (IC50: 59/92 nM) used in breast and prostate cancer studies.Fórmula:C34H33ClN6O7Pureza:99.64%Forma y color:SolidPeso molecular:673.11ALK-IN-1
CAS:ALK-IN-1 is a potent ALK inhibitor, demonstrating the ability to overcome Crizotinib resistance mediated by an L1196M mutation.Fórmula:C26H34ClN6O2PPureza:99.74% - 99.80%Forma y color:SolidPeso molecular:529.01N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine
CAS:Fórmula:C22H24ClFN4O3Pureza:98%Forma y color:SolidPeso molecular:446.9024Anti-EGFR Monoclonal Antibody-APC
Anti-EGFR Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting EGFR. Anti-EGFR Monoclonal Antibody-APC can be used in FACS.Pureza:> 95% as determined by SDS-PAGE.Forma y color:LiquidPeso molecular:150 kDaPoziotinib hydrochloride
CAS:Oral poziotinib HCl targets EGFR/HER mutants, inhibiting cancer cell growth.Fórmula:C23H22Cl3FN4O3Pureza:97.48% - 99.81%Forma y color:SolidPeso molecular:527.8Ref: TM-T8758
5mg55,00€10mg82,00€25mg126,00€50mg182,00€100mg273,00€200mg409,00€500mg677,00€1mL*10mM (DMSO)88,00€
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