Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- Inductor de apoptosis
- ASK
- BCL
- Caspasa
- c-RET
- FOXO1
- IAP
- Mdm2
- p53
- PD-1 / PD-L1
- PDK
- PERK
- Serina / treonina quinasa
- Survivin
- TNF
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Productos de "Apoptosis"
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Hydroxyurea
CAS:Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.Fórmula:CH4N2O2Pureza:99.85% - 99.92%Forma y color:SolidPeso molecular:76.05Mollugin
CAS:Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.Fórmula:C17H16O4Pureza:98.31% - ≥95%Forma y color:SolidPeso molecular:284.31HS-173
CAS:HS-173 is an effective PI3Kα inhibitor (IC50: 0.8 nM).Fórmula:C21H18N4O4SPureza:99.33% - 99.64%Forma y color:SolidPeso molecular:422.46Polyphyllin I
CAS:Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,Fórmula:C44H70O16Pureza:98% - 99.5%Forma y color:SolidPeso molecular:855.02Deracoxib
CAS:Deracoxib (SC 46) is a selective COX-2 inhibitor, non-steroidal, non-narcotic anti-inflammatory drug with an IC50 of 70-150 μM for osteosarcoma cells.Fórmula:C17H14F3N3O3SPureza:100% - 99.81%Forma y color:SolidPeso molecular:397.375-Methoxy-1-(methoxymethoxy)-2-methyl-naphthalene-d3
CAS:Producto controladoApplications 5-Methoxy-1-(methoxymethoxy)-2-methyl-naphthalene-d3 is an intermediate in the synthesis of Plumbagin-d3 (P627002). Plumbagin-d3 is labelled Plumbagin (P627000) which induces apoptosis in cancer cells. It also inhibits NADPH oxidase 4 in a time- and dose-dependent manner. References Klotz, L., et al.: Molecules, 19 14902 (2014); Gupta, S., et al.: Cancer Metastasis Rev., 29, 405 (2010); Schramm, A., et al.: Vascul. Pharmacol., 56, 216 (2012)Fórmula:C14H13D3O3Forma y color:NeatPeso molecular:235.29Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Fórmula:C32H33ClFN5O11Pureza:100% - 98.11%Forma y color:SolidPeso molecular:718.08Ref: TM-T1773
1g467,00€5mg40,00€10mg59,00€25mg87,00€50mg107,00€100mg140,00€200mg188,00€500mg313,00€1mL*10mM (DMSO)66,00€Eupatolide
CAS:Eupatolide, from Inula japonica flowers, has anti-inflammatory properties and aids in researching TRAIL resistance in breast cancer.Fórmula:C15H20O3Pureza:98%Forma y color:SolidPeso molecular:248.32(±)-Shikonin
CAS:Fórmula:C16H16O5Pureza:>98.0%(HPLC)Forma y color:Orange to Brown powder to crystalPeso molecular:288.302'-epi-2'-O-Acetylthevetin B
CAS:2'-Epi-2'-O-Acetylthevetin B (GHSC-74), a cardiac glycoside extractable from Cerbera manghas L.Fórmula:C44H68O19Pureza:98%Forma y color:SolidPeso molecular:901Fludarabine
CAS:Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation.Fórmula:C10H12FN5O4Pureza:100% - 99.88%Forma y color:White SolidPeso molecular:285.23Troglitazone
CAS:Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Fórmula:C24H27NO5SPureza:98% - 99.62%Forma y color:Yellow SolidPeso molecular:441.54Ref: TM-T3170
2mg42,00€5mg62,00€10mg88,00€25mg172,00€50mg305,00€100mg558,00€500mg1.169,00€1mL*10mM (DMSO)85,00€VER-50589
CAS:VER-50589 is a potent HSP90 inhibitor.Fórmula:C19H17ClN2O5Pureza:100% - 99.96%Forma y color:SolidPeso molecular:388.8Ref: TM-T2258
1mg42,00€5mg97,00€10mg159,00€25mg264,00€50mg404,00€100mg588,00€200mg832,00€1mL*10mM (DMSO)97,00€MI-1061
CAS:MI-1061 is a orally bioavailable inhibitor of MDM2 (MDM2-p53 interaction) (IC50=4.4 nM).Fórmula:C30H26Cl2FN3O4Forma y color:SolidPeso molecular:582.45NLRP3-IN-72
CAS:NLRP3-IN-72 (Compound 2) is a benzimidazole derivative. It exhibits anti-inflammatory and antioxidant properties, with an IC50 of 0.3 μM for NLRP3 IL-1β, a PD50 of 0.4 μM for protection against cell pyroptosis, and an EC50 of 0.6 μM for inducing HO-1.Fórmula:C19H20FN5OForma y color:SolidPeso molecular:353.393Tripterin
CAS:Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.Fórmula:C29H38O4Pureza:98.56% - 99.8%Forma y color:Red Crystalline PowderPeso molecular:450.61Oncrasin-1
CAS:Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrationsFórmula:C16H12ClNOPureza:99.75%Forma y color:SolidPeso molecular:269.73Bendamustine hydrochloride
CAS:Bendamustine hydrochloride (EP-3101) (IC50 of 50 μM) is an alkylating agent associated with DNA damage.Fórmula:C16H21Cl2N3O2·HClPureza:97.71%Forma y color:SolidPeso molecular:394.72Ferroptosis-IN-3
Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM).Pureza:98%Forma y color:Odour Solid
