Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa
- CDK
- Detención del ciclo celular
- Chk
- c-Myc
- Dynamin
- DYRK
- Ferroptosis
- HSP
- Integrin
- Kinesina
- KSP
- LIM quinasa
- Asociado a microtúbulos
- PKC
- PLK
- Rho
- ROCK
- Wee1
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Productos de "Ciclo celular / Checkpoint"
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N2-Methylguanosine
CAS:N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA'sFórmula:C11H15N5O5Pureza:97.77%Forma y color:SolidPeso molecular:297.27PNU112455A hydrochloride
CAS:PNU112455A hydrochloride is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.Fórmula:C10H12ClN5O2SPureza:98.58% - 99.22%Forma y color:SolidPeso molecular:301.75Ref: TM-T8230
2mg47,00€5mg74,00€10mg105,00€25mg182,00€50mg281,00€100mg459,00€500mg1.017,00€1mL*10mM (DMSO)84,00€L82-G17
CAS:L82-G17 is an uncompetitive LigI-selective inhibitor in human cells with utility as a probe of the catalytic activity and cellular functions of LigI.Fórmula:C11H9ClN4O2Pureza:99.78%Forma y color:SolidPeso molecular:264.67αVβ8-IN-1
CAS:αVβ8-IN-1 is an inhibitor of the αVβ8 integrin. It exhibits growth-suppressive activity against tumors such as EMT6, CT26, KPC, and TKCC-10. αVβ8-IN-1 is suitable for research related to idiopathic pulmonary fibrosis (IPF), nonspecific interstitial pneumonia (NSIP), and various cancers.Fórmula:C25H32ClN5O4Forma y color:SolidPeso molecular:502.01Pritelivir
CAS:Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).Fórmula:C18H18N4O3S2Pureza:97.96% - 99.42%Forma y color:SolidPeso molecular:402.49Anti-EMMPRIN/CD147 Antibody
Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.Forma y color:Odour LiquidTipiracil hydrochloride
CAS:Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI).Fórmula:C9H12Cl2N4O2Pureza:100% - ≥95%Forma y color:SolidPeso molecular:279.12Bimosiamose
CAS:Bimosiamose has anti-inflammatory effects[1].Fórmula:C46H54O16Pureza:98%Forma y color:SolidPeso molecular:862.91αvβ1 integrin-IN-1
CAS:αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.Fórmula:C26H34N6O6SPureza:100% - 99.74%Forma y color:SolidPeso molecular:558.65Ref: TM-T13473
1mg115,00€5mg274,00€10mg432,00€25mg697,00€50mg938,00€100mg1.293,00€200mg1.738,00€1mL*10mM (DMSO)349,00€DHX9-IN-4
CAS:DHX9-IN-4 is an ATP-dependent RNA helicase DHX9 inhibitor used in cancer research.Fórmula:C21H22ClN5O4S2Pureza:98.12%Forma y color:SolidPeso molecular:508.01PDL-1 cpd 10
CAS:PDL-1 cpd 10 is a novel small molecule PD-L1 inhititor.Fórmula:C21H23N5O2Pureza:97.08%Forma y color:SolidPeso molecular:377.44Ref: TM-T9359
1mg55,00€5mg117,00€10mg187,00€25mg393,00€50mg562,00€100mg787,00€200mg1.035,00€1mL*10mM (DMSO)134,00€K34c hydrochloride
K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.Fórmula:C38H50ClN5O2Pureza:100% - 99.95%Forma y color:SoildPeso molecular:644.29Ref: TM-T41151L
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€1mL*10mM (DMSO)887,00€LP23
LP23, a non-arylmethylamine PD-1/PD-L1 inhibitor (IC 50: 16.7 nM), exhibits anti-tumor activity through the restoration of immune cell function in HepG2/JurkatFórmula:C27H27N3O5SPureza:98%Forma y color:SolidPeso molecular:505.59SCH900776
CAS:SCH900776 (MK-8776) is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.Fórmula:C15H18BrN7Pureza:96.69% - 99.6%Forma y color:SolidPeso molecular:376.25Ref: TM-T2517
1mg52,00€2mg78,00€5mg115,00€10mg168,00€25mg283,00€50mg462,00€100mg660,00€1mL*10mM (DMSO)124,00€Lifitegrast sodium
CAS:Lifitegrast sodium (SAR-1118-023 sodium) is an integrin antagonist that reduces ocular surface inflammation and can be used to study dry eye.Fórmula:C29H23Cl2N2NaO7SPureza:99.33%Forma y color:SolidPeso molecular:637.46Pembrolizumab
CAS:Pembrolizumab (MK-3475) is a humanized monoclonal antibody.Cost-effective and quality-assured.Pureza:95% - 99.70%Forma y color:LiquidPeso molecular:149 kDaART812
CAS:ART812 is an orally active inhibitor of DNA polymerase Polθ, possessing an IC50 value of 7.6 nM.Fórmula:C19H16ClF4N3O4Pureza:99.32%Forma y color:SolidPeso molecular:461.79Ref: TM-T40236
1mg116,00€5mg283,00€10mg452,00€25mg747,00€50mg1.103,00€100mg1.539,00€1mL*10mM (DMSO)280,00€XU1
CAS:XU1(Benzo[c][1,8]naphthyridin-6(5h)-One) is an Aurora protein kinase inhibitor used for the treatment of diseases suitable for inhibition, regulation orFórmula:C12H8N2OPureza:100% - 98.97%Forma y color:SolidPeso molecular:196.2Atuveciclib
CAS:Atuveciclib Racemate is an oral CDK9 inhibitor with a 13 nM IC50, targeting P-TEFb/CDK9 selectively.Fórmula:C18H18FN5O2SPureza:97.29%Forma y color:SolidPeso molecular:387.43Ref: TM-T10464L
1mg88,00€2mg120,00€5mg202,00€10mg329,00€25mg612,00€50mg817,00€100mg1.121,00€1mL*10mM (DMSO)224,00€CDK7-IN-22
CAS:CDK7-IN-22 (compound 101) is a selective CDK7 inhibitor that exhibits antitumor activity, demonstrating specificity for CDK7 [1].Fórmula:C22H25F3N6Pureza:98%Forma y color:SolidPeso molecular:430.47
