Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa
- CDK
- Detención del ciclo celular
- Chk
- c-Myc
- Dynamin
- DYRK
- Ferroptosis
- HSP
- Integrin
- Kinesina
- KSP
- LIM quinasa
- Asociado a microtúbulos
- PKC
- PLK
- Rho
- ROCK
- Wee1
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Productos de "Ciclo celular / Checkpoint"
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IMT1
CAS:IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.Fórmula:C21H21NO4Pureza:98.07% - 98.14%Forma y color:SolidPeso molecular:351.4Ref: TM-T8841
1mg81,00€5mg170,00€10mg301,00€25mg563,00€50mg805,00€100mg1.111,00€1mL*10mM (DMSO)188,00€PHI-101
CAS:PHI-101 is a checkpoint kinase 2 (Chk2) inhibitor that can be used for the study of refractory acute myeloid leukemia (AML) and ovarian cancer.Fórmula:C19H19FN4O2SPureza:99.40%Forma y color:SolidPeso molecular:386.44Ref: TM-T81490
1mg173,00€5mg437,00€10mg702,00€25mg1.406,00€50mg2.262,00€100mg3.600,00€1mL*10mM (DMSO)469,00€SEL120-34A HCl
CAS:SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectivelyFórmula:C15H19Br2ClN4Pureza:98.13% - 99.75%Forma y color:SolidPeso molecular:450.6(S)-GNA-T-phosphoramidite
CAS:(S)-GNA-T-phosphoramidite is a nucleoside analog commonly used in the synthesis of other active compounds.Fórmula:C38H47N4O7PPureza:99.35%Forma y color:SolidPeso molecular:702.78AZD-5438
CAS:AZD-5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).Fórmula:C18H21N5O2SPureza:99.73% - 99.87%Forma y color:SolidPeso molecular:371.46BUR1
CAS:BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.Fórmula:C16H17N5Pureza:90%Forma y color:SolidPeso molecular:279.34Obtustatin triacetate
Obtustatin triacetate, a 41-residue non-RGD disintegrin isolated from the venom of Vipera lebetina obtusa, serves as a potent and selective inhibitor of theFórmula:C184H284N52O57S8·3C2H4O2Pureza:99.51%Forma y color:SolidPeso molecular:4573.21MYC-RIBOTAC
MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tetheredFórmula:C55H58N10O11SPureza:98%Forma y color:SolidPeso molecular:1067.17Lerociclib dihydrochloride
CAS:Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/Fórmula:C26H36Cl2N8OPureza:97.40%Forma y color:SolidPeso molecular:547.52CCT241533 hydrochloride
CAS:CCT241533 hydrochloride is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).Fórmula:C23H28ClFN4O4Pureza:97.13%Forma y color:SolidPeso molecular:478.95Ref: TM-T10718L
1mg73,00€2mg96,00€5mg159,00€10mg240,00€25mg515,00€50mg852,00€100mg1.264,00€500mg2.547,00€1mL*10mM (DMSO)170,00€DMT-dU-CE Phosphoramidite
CAS:DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA.Fórmula:C39H47N4O8PPureza:97.58%Forma y color:SolidPeso molecular:730.79BMS-1001
CAS:BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).Fórmula:C35H34N2O7Pureza:98.43%Forma y color:SolidPeso molecular:594.7Abciximab
CAS:Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Pureza:SDS-PAGE:95.2%;SEC-HPLC:95.9%Forma y color:LiquidPeso molecular:95.18 kDaVotoplam HCl
CAS:Votoplam HCl is a systemically acting gene splicing regulator that down-regulates the levels of huntingtin protein, which to inhibit Huntington's disease (HD).Fórmula:C21H26ClN9OPureza:99.49%Forma y color:SoildPeso molecular:455.94
