Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa
- CDK
- Detención del ciclo celular
- Chk
- c-Myc
- Dynamin
- DYRK
- Ferroptosis
- HSP
- Integrin
- Kinesina
- KSP
- LIM quinasa
- Asociado a microtúbulos
- PKC
- PLK
- Rho
- ROCK
- Wee1
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Productos de "Ciclo celular / Checkpoint"
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CHK1-IN-4
CAS:CHK1-IN-4 is a potent inhibitor of checkpoint kinase 1 (chk1) and potently inhibits chk1 phosphorylation in the tumor cells with anti-tumor activity.Fórmula:C18H18BrN7O2Pureza:98%Forma y color:SolidPeso molecular:444.29Butylparaben sodium
CAS:Butylparaben sodium significantly impacts the later phases of spermatogenesis in the testes by impairing hormonal regulation and/or RNA and protein synthesis [1Fórmula:C11H13NaO3Pureza:98%Forma y color:SolidPeso molecular:216.21MSC2530818
CAS:MSC2530818 is an effective, selective and orally available CDK8 inhibitor (IC50: 2.6 nM).Fórmula:C18H17ClN4OPureza:98.93%Forma y color:SolidPeso molecular:340.81Ref: TM-TQ0266
1mg66,00€5mg144,00€10mg230,00€25mg509,00€50mg735,00€100mg1.026,00€1mL*10mM (DMSO)159,00€Lucanthone
CAS:Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1).Fórmula:C20H24N2OSPureza:99.92%Forma y color:Yellow Crystals From Alcohol SolidPeso molecular:340.48Ref: TM-T4569
1mg56,00€2mg80,00€5mg126,00€10mg188,00€25mg400,00€50mg592,00€100mg837,00€1mL*10mM (DMSO)140,00€BIO-1211
CAS:BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).Fórmula:C36H48N6O9Pureza:99.33%Forma y color:SolidPeso molecular:708.8Mps1-IN-2
CAS:Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.Fórmula:C26H36N6O3Pureza:96.24% - 99.75%Forma y color:SolidPeso molecular:480.6CDK12-IN-5
CAS:CDK12-IN-5 is a potent CDK12 inhibitor with potential anticancer and antitumor activity, and can be used orally in the study of breast and ovarian cancer.Fórmula:C18H15F5N8OPureza:99.37%Forma y color:SolidPeso molecular:454.36Ref: TM-T40290
1mg165,00€5mg399,00€10mg645,00€25mg1.320,00€50mg2.080,00€100mg2.822,00€1mL*10mM (DMSO)439,00€Cdc7-IN-5
CAS:Cdc7-IN-5: potent Cdc7 serine-threonine kinase inhibitor, critical for starting DNA replication.Fórmula:C25H23N3O5Pureza:97.15%Forma y color:SolidPeso molecular:445.47Ref: TM-T10727
1mg96,00€5mg227,00€10mg376,00€25mg620,00€50mg847,00€100mg1.169,00€1mL*10mM (DMSO)250,00€COH1
CAS:COH1 is a ribonucleotide reductase (RR) inhibitor utilized in research pertaining to cancer, mitochondrial diseases, and neurodegenerative disorders [1].Fórmula:C11H10N2O3SPureza:98%Forma y color:SolidPeso molecular:250.27Bexotegrast
CAS:Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).Fórmula:C27H36N6O3Pureza:99.53%Forma y color:SolidPeso molecular:492.61Indatuximab
Indatuximab is a chimeric antibody targeting CD13, used in the synthesis of ADC compound Indatuximab ravtansine.Forma y color:LiquidPeso molecular:145.5 kDaHPH-15
CAS:HPH-15 is an anti-cell migration compound that inhibits cell movement by binding to hnRNP U or suppressing TGF-β. Additionally, it prevents epithelial-to-mesenchymal transition (EMT). HPH-15 holds potential for research in areas such as anti-tumor metastasis and anti-fibrosis.Fórmula:C19H31N3S4Forma y color:SolidPeso molecular:429.735-Fluorouridine
CAS:5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine.Fórmula:C9H11FN2O6Pureza:99.53% - 99.76%Forma y color:White PowderPeso molecular:262.19ML264
CAS:ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.Fórmula:C17H21ClN2O4SPureza:99.33% - 99.45%Forma y color:SolidPeso molecular:384.88CDK2-IN-30
CAS:CDK2-IN-30 (Formula (I)) is a CDK2 inhibitor with an IC50 of ≤20 nM, utilized primarily in tumor research.Fórmula:C18H25N7O3SForma y color:SolidPeso molecular:419.502-Fluoroadenine
CAS:2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.Fórmula:C5H4FN5Pureza:99.49%Forma y color:White To Light Yellow Crystal PowderPeso molecular:153.12BS194
CAS:BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.Fórmula:C20H27N5O3Pureza:99.85%Forma y color:SolidPeso molecular:385.463,4-Dihydroxybenzylamine hydrobromide
CAS:3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.Fórmula:C7H10BrNO2Pureza:97.28%Forma y color:Light Beige Crystalline PowderPeso molecular:220.06BMS-688521
CAS:BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.Fórmula:C26H19Cl2N5O4Pureza:98.87%Forma y color:SolidPeso molecular:536.37Ref: TM-T14676
1mg183,00€5mg464,00€10mg655,00€25mg1.169,00€50mg1.539,00€100mg1.882,00€1mL*10mM (DMSO)547,00€LY3405105
CAS:LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-Fórmula:C26H39N7O3Pureza:98.01%Forma y color:SolidPeso molecular:497.63
