Cromatina / Epigenética
Los inhibidores de cromatina/epigenética son compuestos que modulan la estructura y función de la cromatina o interfieren con modificaciones epigenéticas, como la metilación del ADN y la modificación de histonas. Estos inhibidores son herramientas esenciales para estudiar la regulación de la expresión génica y el papel de la epigenética en enfermedades como el cáncer, los trastornos neurológicos y las anomalías del desarrollo. Al dirigirse a los procesos epigenéticos, estos inhibidores pueden alterar los patrones de expresión génica y ofrecer nuevas vías terapéuticas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de cromatina/epigenética de alta calidad para apoyar su investigación en biología molecular, genética y epigenética.
Subcategorías de "Cromatina / Epigenética"
Productos de "Cromatina / Epigenética"
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BETd-260
CAS:BETd-260, a PROTAC linked by a Cereblon ligand and a BET ligand, has an inhibitory effect on BRD4 protein in leukemic cell lines.Fórmula:C43H46N10O6Pureza:96.76%Forma y color:SolidPeso molecular:798.89AU-15330
CAS:AU-15330 is a proteolytic targeting chimera (PROTAC) that simultaneously targets SMARCA4, SMARCA2, and PBRM1 for degradation and exhibits cytotoxicity in H3.3K27M cells but not in H3 wild-type cells. Cost-effective and quality-assured.Fórmula:C39H49N9O5SPureza:100% - 98.21%Forma y color:SolidPeso molecular:755.93Albendazole
CAS:Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.Fórmula:C12H15N3O2SPureza:98.21% - 98.76%Forma y color:Colorless Crystals SolidPeso molecular:265.33CPI-169 racemate
CAS:CPI-169 racemate (CPI 169) is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.Fórmula:C27H36N4O5SPureza:99.59%Forma y color:SolidPeso molecular:528.66Ref: TM-T6809
1mg56,00€2mg79,00€5mg125,00€10mg172,00€25mg376,00€50mg560,00€100mg797,00€1mL*10mM (DMSO)145,00€S-Ruxolitinib
CAS:S-Ruxolitinib can be used in related research in the field of life sciences. Its product number is T3066 and CAS number is 1160597-27-2.Fórmula:C17H18N6Pureza:98%Forma y color:SolidPeso molecular:306.37MAT2A inhibitor 2
CAS:MAT2A inhibitor 2 is an inhibitor of methionine adenosyltransferase 2A (MAT2A).Fórmula:C18H24ClN3O3Pureza:99.52%Forma y color:SolidPeso molecular:365.85Ref: TM-T11950
1mg51,00€5mg106,00€10mg169,00€25mg298,00€50mg445,00€100mg655,00€500mg1.359,00€1mL*10mM (DMSO)119,00€Venadaparib
CAS:Venadaparib, a PARP inhibitor (IC50: 1.4/1.0 nM for PARP1/2), is orally active, selective, not affecting PARP-5, used in tumor studies.Fórmula:C23H23FN4O2Pureza:98.47%Forma y color:SolidPeso molecular:406.45Ref: TM-T9430
1mg48,00€2mg63,00€5mg96,00€10mg144,00€25mg283,00€50mg464,00€100mg680,00€1mL*10mM (DMSO)96,00€PROTAC BRD9 Degrader-6
CAS:PROTAC BRD9 Degrader-6, with an IC50 value of 0.13 nM, is a potent degrader of BRD9 suitable for research on BAF complex-related disorders [1].Fórmula:C47H56N8O6Pureza:98%Forma y color:SolidPeso molecular:829(Rac)-BAY1238097
CAS:(Rac)-BAY1238097 is a inhibitor of BET(IC50 of 1.02 μM for BRD4),used in cancer research.Fórmula:C25H33N5O3Pureza:98%Forma y color:SolidPeso molecular:451.56MS023 dihydrochloride
CAS:MS023 dihydrochloride (MS023 2HCl) is a human type I protein arginine methyltransferase inhibitor with antitumour activity for the study of breast cancer.Fórmula:C17H27Cl2N3OPureza:99.52%Forma y color:SolidPeso molecular:360.32LNK01004
CAS:LNK01004 is a JAK inhibitor that exhibits potent inhibitory effects on JAK1 (IC50: 10 nM), JAK2 (IC50: ＜0.51 nM), and TYK2 (IC50: 1.0 nM). It can concurrently inhibit multiple cytokine-induced p-STAT signaling pathways and is applicable for research on diseases such as atopic dermatitis.Fórmula:C26H31N7O2Forma y color:SolidPeso molecular:473.57Londamocitinib
CAS:Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity.Fórmula:C28H31F2N7O4SPureza:99.47%Forma y color:SolidPeso molecular:599.65Ref: TM-T11706
1mg180,00€5mg439,00€10mg597,00€25mg905,00€50mg1.169,00€100mg1.568,00€1mL*10mM (DMSO)567,00€IDF-11774
CAS:IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).Fórmula:C23H32N2O2Pureza:98.05%Forma y color:SolidPeso molecular:368.51PFI-2
CAS:PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over otherFórmula:C23H25F4N3O3SPureza:99.38%Forma y color:SolidPeso molecular:499.52Methylstat
CAS:Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability.Fórmula:C28H31N3O6Pureza:98.34% - 98.34%Forma y color:SolidPeso molecular:505.56NU 9056
CAS:NU 9056 is an effective and selective inhibitor of KAT5 histone acetyltransferase with an IC50 of 2 µM.Fórmula:C6H4N2S4Pureza:95.36%Forma y color:SolidPeso molecular:232.37Gentiakochianin
CAS:Gentiakochianin (Swertianine), vasodilatory, induce G(2)/M phase and inhibits proliferation, reduces oxLDL-induced , inhibits ROS s,up-regulated Akt/CREB/eNOS.Fórmula:C14H10O6Pureza:98.97%Forma y color:SolidPeso molecular:274.23E-7386
CAS:E-7386 is an oral active CBP/ -catenin modulator.Fórmula:C39H48FN9O4Pureza:98.92% - 99%Forma y color:SolidPeso molecular:725.85Ref: TM-T11136
1mg87,00€5mg255,00€10mg376,00€25mg647,00€50mg920,00€100mg1.225,00€1mL*10mM (DMSO)399,00€MLN8054
CAS:MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Fórmula:C25H15ClF2N4O2Pureza:98.07% - 98.26%Forma y color:SolidPeso molecular:476.86Ref: TM-T6315
1mg52,00€2mg71,00€5mg88,00€10mg127,00€25mg233,00€50mg376,00€100mg567,00€1mL*10mM (DMSO)93,00€CPI-637
CAS:CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.Fórmula:C22H22N6OPureza:99.75% - 99.91%Forma y color:SolidPeso molecular:386.45
