GPR
Los receptores acoplados a proteínas G (GPRs) son una gran familia de receptores de superficie celular que desempeñan un papel crucial en la transmisión de señales de hormonas, neurotransmisores y otros ligandos extracelulares hacia el interior de la célula. Los GPRs están involucrados en una amplia gama de procesos fisiológicos, incluyendo la regulación hormonal, la respuesta inmune y la percepción sensorial. Modificar la actividad de los GPR es una estrategia clave en el desarrollo de terapias para diversas enfermedades, incluyendo trastornos endocrinos, enfermedades cardiovasculares y condiciones neurológicas. En CymitQuimica, ofrecemos una selección de moduladores de GPR de alta calidad para apoyar su investigación en señalización celular, endocrinología y descubrimiento de fármacos.
Productos de "GPR"
Ordenar por
GPR41 agonist-1
CAS:GPR41 agonist-1 is a GPR41 agonist, used for studying metabolic diseases such as diabetes and obesity.Fórmula:C24H23N3O4Pureza:98.40%Forma y color:SolidPeso molecular:417.46AMG-009
CAS:AMG-009 is a prostaglandin D2 antagonist. For CRTH2 and DP receptors, the IC50s are 3 nM and 12 nM, respectively.Fórmula:C26H26Cl2N2O7SPureza:97.88%Forma y color:SolidPeso molecular:581.47WAY-298630
CAS:Fluorophenoxy benzimidazole, a CRTH2 blocker, IC50 < 10 μM for rhinitis, COPD, arthritis, eczema, conjunctivitis.Fórmula:C17H15FN2O3SPureza:97.13%Forma y color:SolidPeso molecular:346.38Bimatoprost acid
CAS:Bimatoprost acid (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and has a potential antagonistic activity for the FP receptor.Fórmula:C23H32O5Pureza:99.29%Forma y color:SolidPeso molecular:388.5Ref: TM-T20939
1mg133,00€5mg304,00€10mg452,00€25mg740,00€50mg1.026,00€100mg1.388,00€1mL*10mM (DMSO)325,00€CRTh2 antagonist 1
CAS:CRTh2 antagonist 1 is a CRTh2 antagonist (IC50: 89 nM).Fórmula:C23H25N3O5SPureza:97.39%Forma y color:SolidPeso molecular:455.53Ref: TM-T10084
1mg115,00€5mg255,00€10mg374,00€25mg562,00€50mg787,00€100mg1.074,00€500mg2.147,00€1mL*10mM (DMSO)283,00€Questiomycin A
CAS:Questiomycin A: crème fraiche antibiotic with antibacterial, anticancer effects; inhibits GRP78.Fórmula:C12H8N2O2Pureza:98% - 99.07%Forma y color:SolidPeso molecular:212.2Ginsenoside Rb2
CAS:Ginsenoside Rb2 (Ginsenoside C) found in species of Panax, upregulating GPR120 gene expression.Fórmula:C53H90O22Pureza:99.01% - 99.66%Forma y color:White PowderPeso molecular:1079.27CAY10595
CAS:CAY10595 is an antagonist of the CRTh2 (DP2) receptor with a Ki of 10 nM.Fórmula:C20H13Cl2FN2O5Pureza:100% - 99.71%Forma y color:SolidPeso molecular:451.23Latanoprost
CAS:Latanoprost (Xalatan) is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect.Fórmula:C26H40O5Pureza:99.69% - 99.78%Forma y color:Pale Yellow OilPeso molecular:432.59Ref: TM-T2528
1mg47,00€2mg59,00€5mg88,00€10mg142,00€25mg274,00€50mg408,00€100mg603,00€500mg1.293,00€1mL*10mM (DMSO)87,00€AM-4668
CAS:AM-4668, a GPR40 (FFA1) agonist with oral availability, was optimized to reduce central nervous system (CNS) permeability, and reduced blood glucose level.Fórmula:C24H19F3N2O4SPureza:100% - 99.92%Forma y color:SolidPeso molecular:488.48AF64394
CAS:AF64394 is a selective inverse agonist of GPR3(pIC50 : 7.3)Fórmula:C21H20ClN5OPureza:97.22%Forma y color:SolidPeso molecular:393.87GPCR agonist-2
CAS:GPCR agonist-2 (4-(Cyclopropylamino)-3-nitrobenzoic acid) is an agonist of the orphan human GPCR GPR109B.Fórmula:C10H10N2O4Pureza:99.94%Forma y color:SolidPeso molecular:222.2NE 52-QQ57
CAS:NE 52-QQ57 is a selective, and orally available antagonist of GPR4(IC50 : 70 nM),with anti-inflammatory activity.Fórmula:C24H28N6OPureza:98.63%Forma y color:SolidPeso molecular:416.52Ref: TM-T11461
1mg73,00€5mg160,00€10mg235,00€25mg394,00€50mg587,00€100mg835,00€1mL*10mM (DMSO)170,00€6-OAU
CAS:6-OAU is a GPR84 agonist, activates it in HEK293 cells with a 105 nM EC50.Fórmula:C12H21N3O2Pureza:99.01% - 99.68%Forma y color:SolidPeso molecular:239.31Ref: TM-T2036
1mg160,00€2mg215,00€5mg329,00€10mg472,00€25mg753,00€50mg1.074,00€100mg1.444,00€1mL*10mM (DMSO)301,00€TAK-041
CAS:TAK-041 (NBI-1065846) is a potent and selective GPR139 agonist.Fórmula:C18H15F3N4O3Pureza:99.95%Forma y color:SolidPeso molecular:392.33Ref: TM-T9317
1mg37,00€5mg144,00€10mg225,00€25mg452,00€50mg723,00€100mg1.130,00€200mg1.501,00€1mL*10mM (DMSO)159,00€Grp94 Inhibitor-1
CAS:Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).Fórmula:C22H28N2O2Pureza:97.02%Forma y color:SolidPeso molecular:352.47BTB09089
CAS:BTB09089 (GPR65 agonist ) is a T cell death-associated gene 8 (TDAG8/GPR65)-specific agonist.BTB09089 induces TDAG8 expression and regulates cytokine productionFórmula:C14H12Cl2N4OS2Pureza:100%Forma y color:SoildPeso molecular:387.31Acifran
CAS:Acifran (AY 25712) is an HM74A/GPR109A and GPR109B agonist and displays antihyperlipidemic activity.Fórmula:C12H10O4Pureza:98.65%Forma y color:SolidPeso molecular:218.21APD597
CAS:APD597 (JNJ-38431055) is a GPR119 agonist, used in the treatment of type 2 diabetes.Fórmula:C21H29N5O6SPureza:99.63% - 99.78%Forma y color:SolidPeso molecular:479.55GPR81 agonist 1
CAS:GPR81 agonist 1 is a GPR81 agonist that improves glycaemic control in insulin-resistant mouse models for the study of diabetes and obesity.Fórmula:C22H30N4O2S2Pureza:99.68%Forma y color:SolidPeso molecular:446.63
