GPR
Los receptores acoplados a proteínas G (GPRs) son una gran familia de receptores de superficie celular que desempeñan un papel crucial en la transmisión de señales de hormonas, neurotransmisores y otros ligandos extracelulares hacia el interior de la célula. Los GPRs están involucrados en una amplia gama de procesos fisiológicos, incluyendo la regulación hormonal, la respuesta inmune y la percepción sensorial. Modificar la actividad de los GPR es una estrategia clave en el desarrollo de terapias para diversas enfermedades, incluyendo trastornos endocrinos, enfermedades cardiovasculares y condiciones neurológicas. En CymitQuimica, ofrecemos una selección de moduladores de GPR de alta calidad para apoyar su investigación en señalización celular, endocrinología y descubrimiento de fármacos.
Productos de "GPR"
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Fezagepras sodium
CAS:Fezagepras sodium (Setogepram sodium salt) is an orally active GPR40 agonist and is an antagonist or inverse agonist for GPR84, with anti-fibrotic, anti-Fórmula:C13H17NaO2Pureza:99.59%Forma y color:SolidPeso molecular:228.26Ref: TM-T12375
1mg43,00€5mg96,00€10mg140,00€25mg255,00€50mg374,00€100mg542,00€500mg1.093,00€1mL*10mM (DMSO)96,00€Palosuran hydrochloride 540769-28-6(free base)
Palosuran hydrochloride 540769-28-6(free base)(ACT-058362 hydrochloride) is a new potent and specific antagonist of the human UT receptor with an IC50 of 3.6±0.Fórmula:C25H31ClN4O2Pureza:99.75%Forma y color:SolidPeso molecular:454.99Ramatroban
CAS:Ramatroban (BAY u3405) (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis.Fórmula:C21H21FN2O4SPureza:98.12% - 99.96%Forma y color:Crystalline SolidPeso molecular:416.47Ref: TM-T2396
5mg38,00€10mg57,00€25mg95,00€50mg170,00€100mg274,00€200mg354,00€500mg597,00€1mL*10mM (DMSO)63,00€Ogremorphin
CAS:Ogremorphin (GPR68-IN-1) is a potent inhibitor of GPR68, exhibiting an EC50 of 170 nM.it is utilized in the study of autoimmune chronic inflammatory diseases [1Fórmula:C21H17N3OSPureza:99.65% - 99.65%Forma y color:SolidPeso molecular:359.44DJ-V-159
CAS:DJ-V-159 is a GPRC6A agonist, targeting the G protein-coupled receptor family C group 6 member A (GPRC6A).Fórmula:C24H12F6N4O2Pureza:99.85% - 99.96%Forma y color:SolidPeso molecular:502.37LY2881835
CAS:LY2881835 is a potent and selective GPR40 agonist.Fórmula:C33H33NO3Pureza:97.65% - 97.65%Forma y color:SolidPeso molecular:491.62APD668
CAS:APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.Fórmula:C21H24FN5O5SPureza:99.45% - 99.97%Forma y color:SolidPeso molecular:477.51GPR40/FFAR1 modulator 1
CAS:GPR40/FFAR1 modulator 1 is a Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1) agonist and allosteric modulator.Fórmula:C21H19N5O3Pureza:99.72%Forma y color:SolidPeso molecular:389.41NOX-6-18
CAS:NOX-6-18 (GPR132-B-160) is a GPR132 antagonist with insulin-promoting activity and reduced weight gain.Fórmula:C18H17NO5SPureza:99.29%Forma y color:SoildPeso molecular:359.4hGPR91 antagonist 3
CAS:hGPR91 antagonist 3 is an hGPR91 antagonist. hGPR91 antagonist 3 can be used to study diseases in hypertension and retinal angiogenesis.Fórmula:C23H18F4N4O2Pureza:98.82% - 98.82%Forma y color:SolidPeso molecular:458.41Latanoprost acid
CAS:Latanoprost acid is a prostanoid receptor agonist that blocks RANKL and can be used to reduce intraocular pressure.Fórmula:C23H34O5Pureza:96.97%Forma y color:Pale Yellow OilPeso molecular:390.51Ref: TM-T15718
1mg57,00€5mg145,00€10mg226,00€25mg454,00€50mg672,00€100mg924,00€200mg1.225,00€1mL*10mM (DMSO)160,00€GSK1292263
CAS:GSK1292263 is a GPR119 agonist and has been investigated for the treatment of DIABETES MELLITUS, TYPE 2.Fórmula:C23H28N4O4SPureza:98.34% - 99.46%Forma y color:SolidPeso molecular:456.56NCRW0005-F05
CAS:NCRW0005-F05 is a potent agonist of orphan G-protein coupled receptor GPR139 with an IC 50 value of 0.21 μM.Fórmula:C16H13F2NO2Pureza:99.48%Forma y color:SolidPeso molecular:289.28P2Y2R/GPR17 antagonist 1
CAS:P2Y2R/GPR17 antagonist 1 (Compound 14m) is a dual P2Y2R (IC50: 3.17 μM) and GPR17 (IC50: 1.67 μM) antagonist.Fórmula:C19H13ClN2O6SPureza:98.21%Forma y color:SolidPeso molecular:432.83YL-365
YL-365 is a highly potent and selective GPR34 antagonist that exhibits excellent activity in neuropathic pain models for the study of neurologic diseases.Pureza:98.51%Forma y color:Odour Solid7-FluorotryptaMine HCl
CAS:7-FluorotryptaMine HCl is a potent aromatic monoamine GPRC5A agonist that induces GPRC5A-mediated β-arrestin recruitment.7-FluorotryptaMine HCl can be used toFórmula:C10H12ClFN2Pureza:98.06%Forma y color:SolidPeso molecular:214.67GW9508
CAS:GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.Fórmula:C22H21NO3Pureza:97.89% - 99.19%Forma y color:SolidPeso molecular:347.41GPR40 Agonist 2
CAS:GPR40 Agonist 2 is a GPR40 agonist. It can be used in the research of diabetes.Fórmula:C24H30O3Pureza:98%Forma y color:SolidPeso molecular:366.49Myristyl nicotinate
CAS:Myristyl nicotinate (Tetradecyl nicotinate) is an ester prodrug being developed for delivery of nicotinic acid (NIC) into the skin for prevention of actinicFórmula:C20H33NO2Pureza:99.50%Forma y color:SolidPeso molecular:319.48LY2922470
CAS:LY2922470: Selective GPR40 agonist; EC50=7nM (human), 1nM (mouse), 3nM (rat); lowers glucose, boosts insulin/GLP-1.Fórmula:C28H29NO4SPureza:93.34% - 96%Forma y color:SolidPeso molecular:475.6Ref: TM-T15810
1mg115,00€5mg236,00€10mg355,00€25mg617,00€50mg879,00€100mg1.198,00€1mL*10mM (DMSO)248,00€
