GPR
Los receptores acoplados a proteínas G (GPRs) son una gran familia de receptores de superficie celular que desempeñan un papel crucial en la transmisión de señales de hormonas, neurotransmisores y otros ligandos extracelulares hacia el interior de la célula. Los GPRs están involucrados en una amplia gama de procesos fisiológicos, incluyendo la regulación hormonal, la respuesta inmune y la percepción sensorial. Modificar la actividad de los GPR es una estrategia clave en el desarrollo de terapias para diversas enfermedades, incluyendo trastornos endocrinos, enfermedades cardiovasculares y condiciones neurológicas. En CymitQuimica, ofrecemos una selección de moduladores de GPR de alta calidad para apoyar su investigación en señalización celular, endocrinología y descubrimiento de fármacos.
Productos de "GPR"
Ordenar por
CAY10786
CAS:CAY10786 (GPR52 antagonist-1) is an antagonist of G protein-coupled receptor 52 (GPR52, IC50 = 0.63 μM).Fórmula:C15H14OSPureza:99.84%Forma y color:SolidPeso molecular:242.34IBC 293
CAS:IBC 293: Selective GPR109B agonist, favoring it over GPR109A; targets receptor in fat cells.Fórmula:C10H11N3O2Pureza:99.63%Forma y color:SolidPeso molecular:205.21MK-6892
CAS:MK-6892 is a selective and full agonist for the high-affinity nicotinic acid receptor GPR109A (Ki: 4 nM; GTPγS EC50: 16 nM).Fórmula:C19H22N4O5Pureza:99.01% - 99.03%Forma y color:SolidPeso molecular:386.4Ref: TM-TQ0108
1mg97,00€5mg188,00€10mg283,00€25mg472,00€50mg655,00€100mg944,00€500mg1.882,00€1mL*10mM (DMSO)230,00€MK-7246
CAS:MK-7246 is a potent and specific CRTH2 antagonist (Ki: 2.5 nM).Fórmula:C21H21FN2O4SForma y color:SolidPeso molecular:416.47GW-1100
CAS:GW-1100 is a selective GPR40 and FFAR1 antagonist for the study of diabetes and metabolic diseases.Fórmula:C27H25FN4O4SPureza:97.01%Forma y color:SolidPeso molecular:520.58MBX-2982
CAS:MBX-2982 is a selective, orally-available GPR119 agonist, used for the treatment of diabetes.Fórmula:C22H24N8OSPureza:98% - 99.96%Forma y color:SolidPeso molecular:448.54Ref: TM-T1793
1mg50,00€5mg106,00€10mg177,00€25mg321,00€50mg487,00€100mg730,00€200mg998,00€1mL*10mM (DMSO)117,00€FL104
CAS:FL104 is a potent agonist of small-molecule urotensin II receptor, pEC50= 7.11.Fórmula:C24H25ClN2OPureza:99.46%Forma y color:SolidPeso molecular:392.92Ref: TM-T27328
1mg116,00€5mg273,00€10mg373,00€25mg563,00€50mg758,00€100mg998,00€200mg1.320,00€1mL*10mM (DMSO)333,00€GSK256073
CAS:GSK256073 is an orally active GPR109A agonist.Fórmula:C10H13ClN4O2Pureza:98.03%Forma y color:SolidPeso molecular:256.69Ref: TM-T15432
1mg73,00€2mg97,00€5mg160,00€10mg250,00€25mg439,00€50mg647,00€100mg920,00€1mL*10mM (DMSO)170,00€AS1269574
CAS:AS1269574 is a potent, orally available GPR119 agonist. AS1269574(AS 1269574) has the potential for the research of type 2 diabetes.Fórmula:C13H14BrN3OPureza:99.99%Forma y color:SolidPeso molecular:308.17Ref: TM-T21623
2mg39,00€5mg57,00€10mg96,00€25mg168,00€50mg270,00€100mg406,00€200mg592,00€1mL*10mM (DMSO)66,00€3-Hydroxyoctanoic Acid
CAS:3-Hydroxyoctanoic Acid, an energy metabolism intermediate, activates orphan receptor GPR109B.Fórmula:C8H16O3Pureza:97.82% - ≥98%Forma y color:SolidPeso molecular:160.21TC-O 9311
CAS:TC-O 9311 (TCO-9311) is an effective agonist of GPR139 (EC50 = 39 nM in CHO-K1 cells expressing human GPR139).Fórmula:C20H19N3O4Pureza:99.24% - 99.84%Forma y color:SolidPeso molecular:365.38Ref: TM-T4626L
5mg49,00€10mg77,00€25mg134,00€50mg207,00€100mg339,00€200mg480,00€1mL*10mM (DMSO)50,00€Pamoic acid
CAS:Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.Fórmula:C23H16O6Pureza:99.99%Forma y color:Fine Yellow PowderPeso molecular:388.37CVN424
CAS:CVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.Fórmula:C24H29F2N5O3Pureza:99.02%Forma y color:SolidPeso molecular:473.52Ref: TM-T9346
1mg96,00€5mg243,00€10mg376,00€25mg630,00€50mg898,00€100mg1.216,00€1mL*10mM (DMSO)253,00€GLPG1205
CAS:GLPG1205 is a potent, orally active GPR84 (G protein-coupled receptor) antagonist with anti-inflammatory activity.Fórmula:C22H22N2O4Pureza:95.97% - 99.34%Forma y color:SolidPeso molecular:378.42Ref: TM-T11411
1mg96,00€5mg207,00€10mg354,00€25mg597,00€50mg852,00€100mg1.159,00€1mL*10mM (DMSO)226,00€TUG-891
CAS:TUG-891 is a G protein-coupled receptor expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids.Fórmula:C23H21FO3Pureza:98.28% - 99.21%Forma y color:SolidPeso molecular:364.41Ref: TM-T3433
1mg40,00€2mg51,00€5mg85,00€10mg115,00€25mg225,00€50mg378,00€100mg552,00€500mg1.169,00€1mL*10mM (DMSO)93,00€SNAP 94847
CAS:SNAP 94847 (SNAP-94847) is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM).Fórmula:C29H32F2N2O2Pureza:98%Forma y color:SolidPeso molecular:478.57CAY10471 Racemate
CAS:CAY10471 Racemate is a potent CRTH2/DP2 antagonist with Ki of 0.6 nM; less active on DP1 and TP.Fórmula:C21H21FN2O4SPureza:99.08%Forma y color:SolidPeso molecular:416.47BMS-903452
CAS:BMS-903452: potent GPR119 agonist, EC50 = 14 nM, treats rodent diabetes, no P450 inhibition, safe for liver cells.Fórmula:C21H19Cl2FN4O4SPureza:100% - 100%Forma y color:SolidPeso molecular:513.37Ref: TM-T67791
1mg90,00€5mg220,00€10mg311,00€25mg469,00€50mg632,00€100mg855,00€200mg1.121,00€1mL*10mM (DMSO)258,00€Vincamine
CAS:Vincamine, from Vinca minor, is an alkaloid used as a vasodilator and antihypertensive for brain circulation issues.Fórmula:C21H26N2O3Pureza:98.96%Forma y color:White To Almost White Fine Crystalline PowderPeso molecular:354.44GPR4 antagonist 1
CAS:GPR4 antagonist 1 is a GPR4 antagonist (IC50: 189 nM).Fórmula:C27H37N5Pureza:98%Forma y color:SolidPeso molecular:431.62
