GPR
Los receptores acoplados a proteínas G (GPRs) son una gran familia de receptores de superficie celular que desempeñan un papel crucial en la transmisión de señales de hormonas, neurotransmisores y otros ligandos extracelulares hacia el interior de la célula. Los GPRs están involucrados en una amplia gama de procesos fisiológicos, incluyendo la regulación hormonal, la respuesta inmune y la percepción sensorial. Modificar la actividad de los GPR es una estrategia clave en el desarrollo de terapias para diversas enfermedades, incluyendo trastornos endocrinos, enfermedades cardiovasculares y condiciones neurológicas. En CymitQuimica, ofrecemos una selección de moduladores de GPR de alta calidad para apoyar su investigación en señalización celular, endocrinología y descubrimiento de fármacos.
Productos de "GPR"
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Fezagepras
CAS:Fezagepras (Setogepram) is an orally active GPR40 agonist and is an antagonist or inverse agonist of GPR84 with anti-inflammatory, anti-fibrotic, and anti-Fórmula:C13H18O2Pureza:96.73% - 99.38%Forma y color:SolidPeso molecular:206.28Ref: TM-T12883
1mg52,00€2mg74,00€5mg96,00€10mg140,00€25mg245,00€50mg350,00€100mgA consultar1mL*10mM (DMSO)93,00€PU-WS13 hydrobromide
PU-WS13 hydrobromide is a GRP94 inhibitor with anti-inflammatory activity and inhibits the proliferation of M2-like macrophages in mouse TNBC tumors.Fórmula:C17H21BrCl2N6SPureza:98.63%Forma y color:SoildPeso molecular:492.26MS21570
CAS:MS21570 as a GPR171 antagonist based on its ability to block,with an IC50 of 220 Nm,that reduces anxiety-like behavior and fear conditioning in mice.Fórmula:C10H11N3S2Pureza:97.79%Forma y color:SolidPeso molecular:237.34BI-671800
CAS:BI-671800 (AP-761) is a DP2/CRTH2 antagonist with IC50 values of 4.5 nM and 3.7 nM, potential for treating asthma.Fórmula:C25H26F3N5O3Pureza:99.19%Forma y color:SolidPeso molecular:501.5Ref: TM-T14565
1mg58,00€5mg131,00€10mg207,00€25mg373,00€50mg530,00€100mg718,00€200mg938,00€1mL*10mM (DMSO)144,00€(1S,2R)-2-PCCA
(1S,2R)-2-PCCA is a novel and potent small molecule GPR88 receptor agonist with an EC50 value of 3 nM in the non-cellular system and 603 nM in the cellularFórmula:C30H39Cl2N3OPureza:99.34%Forma y color:SoildPeso molecular:528.56AZD1981
CAS:AZD1981: selective CRTh2 antagonist, IC50 4 nM, 1000x specificity over 340+ enzymes/receptors, tested in asthma and other trials.Fórmula:C19H17ClN2O3SPureza:98.59% - 99.54%Forma y color:SolidPeso molecular:388.872-Oleoylglycerol
CAS:2-Oleoylglycerol is a lipid found in palm kernels that acts as a GPR119 agonist with neuroprotective properties and can be used in steatohepatitis modeling.Fórmula:C21H40O4Pureza:98%Forma y color:SolidPeso molecular:356.54FTBMT
CAS:FTBMT is a selective GPR52 agonist (EC50: 75 nM) and it also has antipsychotic and procognitive properties.Fórmula:C19H16F4N4OPureza:99.12%Forma y color:SolidPeso molecular:392.35Ref: TM-T15352
5mg52,00€10mg85,00€25mg170,00€50mg301,00€100mg469,00€200mg620,00€1mL*10mM (DMSO)52,00€MEDICA16
CAS:MEDICA16: GPR40 agonist, GPR120 partial agonist, ATP-citrate lyase inhibitor, lowers TG, boosts insulin sensitivity in muscle.Fórmula:C20H38O4Pureza:99.13% - 99.85%Forma y color:White SolidPeso molecular:342.51GLPG0974
CAS:GLPG0974 is an antagonist of FFA2/GPR43 with IC50 of 9 nM.Fórmula:C25H25ClN2O4SPureza:99.58%Forma y color:SolidPeso molecular:484.99AM-1638
CAS:AM-1638 is an orally active GPR40/FFA1 agonist, useful for studying type II diabetes.Fórmula:C33H35FO4Forma y color:SolidPeso molecular:514.63Timapiprant
CAS:Timapiprant (OC000459) is a potent and selective D prostanoid receptor 2 (DP2) antagonist (IC50: 13 nM).Fórmula:C21H17FN2O2Pureza:98.4% - 99.51%Forma y color:SolidPeso molecular:348.37Benzyl nicotinate
CAS:Benzyl nicotinate (Pycaril) is a agonist of GPR109A receptor and GPR109B receptorFórmula:C13H11NO2Pureza:98.22%Forma y color:Yellow LiquidPeso molecular:213.23SNAP 94847 hydrochloride
CAS:SNAP 94847 hydrochloride is a melanin-concentrating hormonereceptor1 (MCHR1) antagonist(Ki= 2.2 nM)Fórmula:C29H33ClF2N2O2Pureza:100% - 99.85%Forma y color:SolidPeso molecular:515.03Ref: TM-T8004
2mg42,00€5mg64,00€10mg97,00€25mg187,00€50mg316,00€100mg455,00€200mg635,00€1mL*10mM (DMSO)71,00€Fevipiprant
CAS:Fevipiprant (NVP-QAW039) is a selective, potent, reversible competitive CRTh2 antagonist.Fórmula:C19H17F3N2O4SPureza:99.32% - 99.59%Forma y color:SolidPeso molecular:426.41(+/-)-Pinocembrin
CAS:(+/-)-Pinocembrin (NSC-43318), a natural product from axillary pines, is a GPR120 ligand that promotes wound healing in the HaCaT cell line.Fórmula:C15H12O4Pureza:99.79%Forma y color:SolidPeso molecular:256.25Dihydromunduletone
CAS:Dihydromunduletone (DHM) is an adhesion G protein-coupled receptor (aGPCR) antagonist inhibits GPR56 and GPR114/ADGRG5, which have similar tethered agonists.Fórmula:C25H28O6Pureza:99.96%Forma y color:SolidPeso molecular:424.49TUG-499
CAS:TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist (EC50: 7.39).TUG-499 has an affinity for FFAR1 or GPR40 over the related receptorsFórmula:C16H11Cl2NO2Pureza:99.59%Forma y color:SoildPeso molecular:320.17Ref: TM-T60184
1mg35,00€5mg74,00€10mg97,00€25mg164,00€50mg212,00€100mg279,00€200mg395,00€1mL*10mM (DMSO)78,00€NF-56-EJ40
CAS:NF-56-EJ40 is an effective and highly selective antagonist of human SUCNR1 with an IC50 of 25 nM and a Ki of 33 nM.Fórmula:C27H29N3O3Pureza:99.51%Forma y color:SolidPeso molecular:443.54Monomethyl fumarate
CAS:Monomethyl fumarate is a potent agonist of GPR109A .Fórmula:C5H6O4Pureza:99.21%Forma y color:SolidPeso molecular:130.1
