Receptor de andrógenos
El receptor de andrógenos (AR) es un receptor hormonal nuclear que se activa al unirse a andrógenos, como la testosterona y la dihidrotestosterona. Este receptor juega un papel crucial en el desarrollo y mantenimiento de las características masculinas, así como en la regulación de varios procesos fisiológicos, incluyendo el crecimiento muscular, la libido y la densidad ósea. Los inhibidores del receptor de andrógenos son ampliamente estudiados en el contexto del cáncer de próstata, donde la señalización del AR a menudo está sobreexpresada. En CymitQuimica, ofrecemos una gama de moduladores del receptor de andrógenos de alta calidad para apoyar su investigación en endocrinología, biología del cáncer y regulación hormonal.
Productos de "Receptor de andrógenos"
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Cyproterone acetate
CAS:Cyproterone acetate (Cyproterone 17-O-acetate) binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues andFórmula:C24H29ClO4Pureza:98.43%Forma y color:Crystals From Diisopropyl Ether OdourPeso molecular:416.943-(7,7-dimethyl-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl)-1H-indole-7-carbonitrile
CAS:3-[7 ,7- dimethyl-5-oxo -6H-pyrrolo[3,4-b]pyridin-2-yI]-1H-indole-7 -carbonitrile is an androgen receptor modulator.Fórmula:C18H14N4OPureza:98.15%Forma y color:SolidPeso molecular:302.33WCA-814
WCA-814, an androgen receptor (AR) antagonist-Hsp90 inhibitor conjugate, induces degradation of both full-length and AR-V7, exhibiting cytotoxic effects inFórmula:C46H53ClN10O5Pureza:98%Forma y color:SolidPeso molecular:861.43Medroxyprogesterone Acetate
CAS:Medroxyprogesterone Acetate (Farlutin) is a synthetic progestin that is derived from 17-hydroxyprogesterone. Farlutin is a long-acting contraceptive.Fórmula:C24H34O4Pureza:99.05% - 99.44%Forma y color:White PowderPeso molecular:386.52BMS-986365
CAS:BMS-986365 (CC-94676) is an orally available, selective and highly potent AR degrader with potential anticancer activity that inhibits AR signaling and suppresses tumor growth for the study of prostate cancer.Fórmula:C41H45F3N8O5SPureza:98.77% - 99.96%Forma y color:SoildPeso molecular:818.91Testosterone undecanoate
CAS:Testosterone undecanoate is a metabolite of Testosterone, which is a promising androgen for male hormonal contraception.Fórmula:C30H48O3Pureza:99.45%Forma y color:White Crystalline PowderPeso molecular:456.7LGD-2226
CAS:LGD-2226: selective oral androgen receptor modulator, EC50: 0.2nM, Ki: 1.5nM. Treats muscle loss, osteoporosis, sexual issues.Fórmula:C14H9F9N2OPureza:98%Forma y color:SolidPeso molecular:392.22TLB 150 Benzoate
CAS:TLB 150 Benzoate (RAD150) is a modulator of the androgen receptor with an IC50 value of 0.13 μM.Fórmula:C27H20ClN5O3Forma y color:SolidPeso molecular:497.93Topterone
CAS:Topterone (Win 17,665) is a potent topical antiandrogen that inhibits the stimulation of lumbar organ development by testosterone and dihydrotestosterone inFórmula:C22H34O2Pureza:100%Forma y color:SolidPeso molecular:330.5Testosterone acetate
CAS:Testosterone acetate (NSC-523836) is a hormone with in vitro antitumor activity.Fórmula:C21H30O3Pureza:99.60%Forma y color:White To Off-White Crystalline PowderPeso molecular:330.46FL442
CAS:FL442 is an Androgen Receptor (AR) modulator. This compound exhibits potent inhibitory effects in AR-dependent prostate cancer cells, showing similar suppression efficiency to the traditional antiandrogen drugs Bicalutamide and Enzalutamide. It also maintains antiandrogen activity against the Enzalutamide-resistant AR mutant F876L. The pharmacokinetic properties of FL442 in mice reveal a longer half-life (8 hours), excellent targeting (prostate tissue), and metabolic stability. Additionally, it is effective at inhibiting LNCaP tumor growth at low plasma concentrations (30 ng/mL).Fórmula:C15H13F3N2OForma y color:SolidPeso molecular:294.27GSK-2881078
CAS:GSK-2881078 is a selective androgen receptor modulato (SARM) that is being evaluated for effects on muscle growth and strength in subjects with muscle wasting.Fórmula:C14H13F3N2O2SPureza:98.16% - 98.81%Forma y color:SolidPeso molecular:330.33Lupeol
CAS:Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.Fórmula:C30H50OPureza:98% - 99.31%Forma y color:Needles From Alcohol Acetone White PowderPeso molecular:426.72Bicalutamide
CAS:Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting theFórmula:C18H14F4N2O4SPureza:98% - 99.87%Forma y color:Off-White Crystalline SolidPeso molecular:430.37Adrenosterone
CAS:Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.Fórmula:C19H24O3Pureza:97.04% - 98.13%Forma y color:SolidPeso molecular:300.39JNJ-63576253 free base
CAS:JNJ-63576253 free base (TRC253) is a potent and orally active full antagonist of androgen receptor (AR). JNJ-63576253 can be used for the research of CRPC.Fórmula:C23H21F3N6O2SPureza:98.32%Forma y color:SolidPeso molecular:502.51Ref: TM-T8933
2mg40,00€5mg52,00€10mg89,00€25mg167,00€50mg258,00€100mg379,00€200mg540,00€1mL*10mM (DMSO)90,00€Apalutamide
CAS:Apalutamide (ARN-509) is a small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity.Fórmula:C21H15F4N5O2SPureza:99.03% - 99.91%Forma y color:SolidPeso molecular:477.43MK-3984
CAS:MK-3984 is a selective androgen receptor modulator, used in the study of conditions caused by androgen deficiency.Fórmula:C17H12F7NO2Pureza:100%Forma y color:SolidPeso molecular:395.27DJ-V-159
CAS:DJ-V-159 is a GPRC6A agonist, targeting the G protein-coupled receptor family C group 6 member A (GPRC6A).Fórmula:C24H12F6N4O2Pureza:99.85% - 99.96%Forma y color:SolidPeso molecular:502.37Nandrolone phenylpropionate
CAS:Nandrolone phenylpropionate (Nandrolone phenpropionate) is an androgen receptor agonist. It mainly used to treat women with breast cancer and osteoporosisFórmula:C27H34O3Pureza:99.2% - 99.46%Forma y color:White Or Milky Crystalline PowderPeso molecular:406.56
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