Enzima

Prostatic Acid Phosphatase (PAP) belongs to the histidine acid phosphatase family.

TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring

Mitogen-activated protein kinase kinase kinase kinase 5, also known as Kinase homologous to SPS1/STE2, MAPK/ERK kinase kinase kinase 5, MEK kinase kinase 5, and

A proprietary potent and stable alternative to chemical neutralizers such as pyruvate - for the utilization in environmental monitoring applications. Use of catalase as a supplement in media plates offers a more effective and reliable solution for safe and secure environmental monitoring of sterilization in clean rooms, isolators or production facilities by also removing remaining traces and spots of high concentration of H2O2. Currently, agar plates for monitoring disinfection or sterilization are supplemented with pyruvate, which is consumed during the neutralization of hydrogen peroxide. One of the main benefits of this catalase is its high stability in agar media at 50°C, which allows easy preparation of media and processing into plates. Due to the high stability no special storage conditions are needed and a shelf-life of > 6 months at 4-25°C can be guaranteed. Key features are: easy to use formulation complete biocatalytic inactivation of hydrogen peroxide (H2O2) a potent, stable alternative to chemical neutralizers more reliable than pyruvate secure and effective degradation with up to 10% H2O2 concentration possibility of irradiation at 20-30 kGy for sterilization of prepared media. This product is a freeze-dried powder formulation, which can be purchased in bulk using the product code ECAT01.6. Liquid formulations and custom formulations are available on request.

Superoxide dismutase is an enzyme that catalyzes the conversion of harmful superoxide into hydrogen peroxide and oxygen.

Kallikrein 7/KLK7 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Transglutaminases (TGase) are a family of calcium-dependent acyl-transfer enzymes ubiquitously expressed in mammalian cells and responsible for catalyzing

Catalyzes an NADPH-dependent reduction of FMN, but is also able to reduce FAD or riboflavin.

Carbonic anhydrase 5A, mitochondrial, also known as Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA and CA5A, is a member of thealpha-carbonic

Serine palmitoyltransferase (SPT).

DNase I (Deoxyribonuclease I, EC 3.1.21.1) is an endonuclease that cleaves DNA, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3'. On average it produces tetranucleotides. One unit of the DNase I will increase the absorbance of 260nm light at a rate of 0.001/minute in 1 ml reaction volume at 25°C.

Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor.

GPX1 Protein, Human, Recombinant (U49S, His) is expressed in E. coli with N-6xHis. The accession number is P07203.

Cathepsin E Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

CD39L1 protein (ENTPD2 or NTPDase2) is a member of the ecto-nucleoside triphosphate diphosphohydrolase family which the main role is termination of purinergic

May be involved in cell growth.

Adenosine kinase(ADK) belongs to the family of transferases.

This product shows beta-lactamase activity against clinically relevant beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. This product may be of particular interest for laboratory teams who require the sterility testing of biological specimens or for environmental monitoring applications.

Lipase 13 recombinantly expressed in E. coli comes in a spray-dried formulation. It has its pH optimum at 6-8 and temp. optimum at 35-45°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 13 was shown to hydrolyze p-Nitrophenyl esters of butyrate (87 % activity compared to octanoate), octanoate (100 %), palmitate (44 %), stearate (21 %) and arachidate (2 %).

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the

PLA2G1B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag.

Aldolase C Protein, Mouse, Recombinant (His & Myc) is expressed in E.

Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.

CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

Responsible for the biosynthesis of pyroglutamyl peptides.

FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.

Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc) is expressed in E.

Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.

UBA6 (Ubiquitin Like Modifier Activating Enzyme 6) is a Protein Coding gene.

N/A.

Ro 61-8048 is a potent and selective inhibitor of kynurenine hydroxylase with an IC50 value of 37 nM.

ABCD1 Protein, Human, Recombinant (His) is expressed in in vitro E. coli expression system.

ACACA Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is Q13085.

Legumain Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Mer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 54 kDa and the accession number is Q12866.

BLM Protein, Mouse, Recombinant (His & Myc) is expressed in E.

Transcription Initiation Factor IIB (TFIIB) is an essential factor for transcription by RNA Polymerase II.

Protein kinase C iota type, also known as Atypical protein kinase C-lambda/iota, aPKC-lambda/iota and PRKCI, is a cytoplasm, membrane and nucleus protein which

Serine / threonine-protein kinase SRPK3, also known as Muscle-specific serine kinase 1, Serine/arginine-rich protein-specific kinase 3, SR-protein-specific

P4HA3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.

PADI2 Protein, Human, Recombinant (His & Myc) is expressed in HEK293.

MMP-9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

PCK2 promotes tumor initiation by lowering acetyl-CoA level through reducing the mitochondrial tricarboxylic acid (TCA) cycle.

PADI2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.

SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine

RIOK3 Protein, Human, Recombinant (E.

Lipase 06 recombinantly expressed in E. coli comes in a freeze-dried formulation. It has its pH optimum at 7 and temp. optimum at 30-45°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 06 was shown to hydrolyze p-Nitrophenyl esters of butyrate (91 % activity compared to octanoate), octanoate (100 %), laurate (13 %), palmitate (1 %), stearate (2 %), arachidate (0.3 %) and behenate (1 %).

NEIL1 is a member of DNA glycosylases.

Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of

Cathepsin A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Has a strict specificity for hydrolysis of asparaginyl bonds.

Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction.

ATP5D is a subunit of mitochondrial ATP synthase.

GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair.

MKK6 Protein, Human, Recombinant (S207D, T211D) is expressed in Baculovirus insect cells.

CK2 alpha/CSNK2A1 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells.

NCEH1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli with N-10xHis, C-Myc. The accession number is Q6PIU2.

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications.

8-oxo-dGTP diphosphatase Protein, E.

Endopeptidase, powder, is a proteolytic enzyme, which is typically derived from microbial, plant, or animal sources, each imparting unique specificities. This enzyme functions by cleaving peptide bonds within polypeptide chains, rather than terminal bonds, thereby facilitating the breakdown of proteins into smaller, more manageable peptide fragments. The mode of action involves recognizing specific amino acid sequences within the substrate, leading to targeted bond hydrolysis. Endopeptidases have wide-ranging applications in both industrial and research settings. In the laboratory, they are instrumental in protein digestion and analysis, aiding in structure-function studies, as well as in preparing proteins for mass spectrometry. In biotechnology and bioprocessing, these enzymes are utilized to modify proteins, optimize protein-based products, and enhance the turnover of proteinaceous waste. Additionally, in the pharmaceutical industry, endopeptidases are being investigated for their therapeutic potential in the treatment of diseases where protein misfolding or aggregation plays a role. Thus, Endopeptidase, powder, represents a versatile tool in the arsenal of protein chemistry and engineering, driving advancements across multiple fields.

L-Asparaginase (EC 3.5.1.1) is an enzyme that catalyzes the following reaction: L-Asparagine + H2O → L-Aspartate + NH4+   One unit will yield 1.0 μmole of ammonia from L-asparagine per min at pH 8.6 and 37 °C.

Casein kinase I gamma 2 isoform (CSNK1G2), a member of the large casein kinase I (CKI) subfamily, protein kinase superfamily.

RAB6B Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is Q9NRW1.

CSNK2A2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

CREBBP Protein, Human, Recombinant (GST) is expressed in E.

Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.

Transaminase with broad substrate specificity.

BoNT/C Protein, Clostridium botulinum, Recombinant (His & SUMO) is expressed in E. coli.

VRK1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

PRKN Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag.

Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI

Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield

Leukotriene A4 Hydrolase Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

GBA2 Protein, Rat, Recombinant (His) is expressed in E.

Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides.

Ubiquitin-Conjugating Enzyme E2 R2 (UBE2R2) is a modification enzyme that belongs to the ubiquitin-conjugating enzyme family.

Sonic Hedgehog Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Degradation of inorganic polyphosphates (polyP).

RUVBL1, also known as RVB1, is a component of the NuA4 histone acetyltransferase complex and belongs to the RuvB family.

IRE1 Protein, Human, Recombinant (aa 465-977) is expressed in Baculovirus insect cells.

Iron-storage protein.

Carbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family.

AKT3 Protein, Mouse, Recombinant (aa 106-479, His & GST) is expressed in Baculovirus insect cells with His and GST tag.

MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases.

CHEK2 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.

HEXA Protein, Human, Recombinant (Subunit A, His) is expressed in Baculovirus insect cells with His tag.

KLK10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.

Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate

Xylanase (Endo-1,4-β-xylanase, 1,4-β-D-Xylanxylanohydrolase, systematic name 4-β-D-xylan xylanohydrolase; EC 3.2.1.8) is an enzyme that digests polysaccharide xylan by hydrolyzing (1→4)-β-D-xylosidic linkages. One unit of Xylanase will hydrolyze 1.0 μmole of chromogenic substrate mimic per minute (available here) under optimal reaction conditions.

NAD Kinase (NADK) is an enzyme that belongs to the NAD Kinase family.

DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to

GAD65 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

EGLN2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli with N-6xHis-SUMO. The accession number is Q96KS0.

A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis.

This protein degrades water-insoluble and water-soluble PHB to monomeric D(-)-3-hydroxybutyrate.

GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor (IC50s: 0.7 nM and 2.3 nM for P. fluorescens-KMO and human KMO).

JNK1 Protein, Human, Recombinant (His) is expressed in Baculovirus Insect Cells with N-6xHis. The accession number is P45983.

Thrombin-like snake venom serine protease that clots fibrinogen by releasing fibrinopeptide A from the alpha chain of fibrinogen (FGA), induces platelet

dUTPase Protein, Human, Recombinant (His) is expressed in E.

Prostaglandin D2 Synthase Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Dog dander is an important cause of respiratory allergy but its content of allergenic components is still incompletely known.

Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha

Has cefotaxime-hydrolyzing activity.

Fukutin Protein, Cynomolgus, Recombinant (His & Myc) is expressed in E.

Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan

HADHA Protein, Mouse, Recombinant (His & Myc) is expressed in E.

Sphingomyelinase (SMase, Sphingomyelin phosphodiesterase, systematic name sphingomyelin cholinephosphohydrolase; EC 3.1.4.12) is an enzyme that hydrolyses sphingomyelin into phosphocholine and ceramide. One unit of sphingomyelinase will hydrolyze 1.0 µmole of chromogenic substrate analogue per minute at pH 7.4 and 37 °C.

Tyrosinase (EC 1.14.18.1) is an enzyme that oxydises phenol derivatives (e.g. tyrosine, dopamine). One unit of tyrosinase dissolved in 3mL reaction mixture will cause the absorbance at 280nm to increase by 0.001 in the presence of L-tyrosine at pH 6.5 and 25 °C. L-tyrosine is available here.Lyophilized, from mushroom. Activity ≥1000 unit/mg

Removes the formyl group from the N-terminal Met of newly synthesized proteins.

CEL-maturity onset diabetes of the young (MODY), diabetes with pancreatic lipomatosis and exocrine dysfunction, is due to dominant frameshift mutations in the

Cysteine proteinase with a strong preference for substrates with Lys in the P1 position.

Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.