Enzima

Malate dehydrogenases 1(MDH1 / MDHA) is a soluble form of malate dehydrogenases.

Removes the formyl group from the N-terminal Met of newly synthesized proteins.

Carbonic Anhydrase 4 Protein, Human, Recombinant (His) is expressed in CHO mammalian cells with His tag.

Ubiquitin-Conjugating Enzyme E2 Z (ZUBE2Z) is a member of the E2 ubiquitin-conjugating enzyme family.

Initiates the repair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and

Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of

NIMA (never in mitosis gene a)-related kinase 7, NEK7 belongs to the NIMA subfamily, NEK Ser/Thr protein kinase family, protein kinase superfamily.

Butyrylcholinesterase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.

CKM, also known as CK-MM, is mainly expressed in skeletal muscle.

Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins, oligosaccharides and gangliosides.

Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate.

HNMT (Histamine N-methyltransferase) is a Protein Coding gene.

Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

SMYD3 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

L-saccharopine oxidase Protein, S.

Hydrolyzes galactooligomers with a degree of polymerization higher than 3.

Peptidyl-prolyl cis-trans isomerase A is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily.

EIF4A2 Protein, Human, Recombinant (GST) is expressed in E.

The kit contains 8 different Glucosyltransferases (GTases), which are enzymes that transfer glucose to another organic molecule (aglycon), establishing glycosidic linkage. UDP-glucose dependent GTases are part of the enzyme family of glucosyltransferases, they are versatile tools in glucosylation reactions. Different GTases have different substrate specificities, as shown on Table 1. The kit is especially designed for screening and finding the most well-suited GTase for your specific process. All GTases in the kit are also available individually for bulk purchase.

Sialic acid aldolase - Aqueous solution is an enzyme preparation used extensively in biochemical and biotechnological applications. It is derived from microbial sources, where it is expressed and purified to high levels for research purposes. Sialic acid aldolase acts by catalyzing the reversible aldol reaction between N-acetylneuraminic acid (sialic acid) and pyruvate, facilitating the cleavage or synthesis of sialic acid. This enzyme is instrumental in the study of sialic acid metabolism and is employed in various applications, including the synthesis of sialic acid derivatives and the structural analysis of complex carbohydrates. Its ability to catalyze the formation and breakdown of sialic acid makes it a valuable tool in the investigation of glycoproteins and glycolipids, which are critical components of cellular communication and pathogen-host interactions. Additionally, the enzyme's application extends to the development of novel therapeutic agents and diagnostic techniques, highlighting its significance in advancing scientific understanding and innovation.

TrkA Protein, Human, Recombinant (aa 194-413, His) is expressed in HEK293 mammalian cells with His tag.

UBE2D4 is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction.

Ribosomal protein S6 kinase alpha-2, also known as 9 kDa ribosomal protein S6 kinase 2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c

Low Molecular Weight Phosphotyrosine Protein Phosphatase (LMW-PTP) is a member of the low molecular weight phosphotyrosine protein phosphatase family.

Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by

N/A.

Arginase 1/ARG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

FTO Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

Major role in the synthesis of nucleoside triphosphates other than ATP.

NMCA (β-Lactamase) is an enzyme, specifically acclaimed for its role in conferring antibiotic resistance. It is derived from bacterial sources, where it naturally occurs as part of the bacterial defense mechanism against β-lactam antibiotics. NMCA (β-Lactamase) functions by hydrolyzing the β-lactam ring present in these antibiotics, effectively rendering them inactive. This mode of action disrupts the antibiotic's ability to inhibit cell wall synthesis within bacteria, thereby permitting bacterial survival and proliferation. The enzyme is primarily used in microbiological and clinical research to study mechanisms of antibiotic resistance. By exploring NMCA (β-Lactamase) activity, scientists aim to better understand resistance patterns and develop novel strategies to combat bacterial infections. Furthermore, its applications extend to drug development, where the enzyme serves as a target for designing inhibitors that can potentiate existing antibiotics' efficacy. The study of NMCA (β-Lactamase) thus plays a critical role in the ongoing battle against antibiotic-resistant bacteria, providing valuable insights into both fundamental microbiology and potential therapeutic interventions.

PTH2, also known as PTRH2, is a mitochondrial protein that belongs to the PTH2 family.

Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate

FLT1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

The ADAMs (a disintegrin and metalloprotease) comprise a family of multidomain proteins with metalloprotease, cell adhesion, and signaling activities.

METTL3 Protein, Human, Recombinant (His) is expressed in E.

Kallikrein-9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag.

GPI Protein, Rat, Recombinant (His & Myc) is expressed in E. coli.

FAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Alkaline Phosphatase/ALPL Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 Cells. The accession number is P05186-1.

MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium.

Catalyzes the NAD(P)H-dependent reduction of mycothione (the oxidized disulfide form of mycothiol) to mycothiol.

Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V.

SCLY, also known as selenocysteine lyase, belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

MMP-8 Protein, Mouse, Recombinant (His) is expressed in CHO mammalian cells with His tag.

LOX Protein, Human, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is P28300.

β-Ureidopropionase is a cytoplasmic protein which belongs to the CN hydrolase family of BUP subfamily.

Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers.

Aspartoacylase 3, also known as ACY3, N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming), Acylase III, Aminoacylase-3, Aspartoacylase-2,

CORIN Protein, Human, Recombinant (His) is expressed in E.

GSTM1 Protein, Mouse, Recombinant (His) is expressed in P. pastoris (Yeast) with N-6xHis. The accession number is P10649.

N/A.

N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine.

Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family.

Degrades casein, gelatins of types I, III, IV, and V, and fibronectin.

Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family.

GPX3 Protein, Human, Recombinant (U73C, hFc) is expressed in HEK293 Cells with N-hFc. The accession number is P22352.

HPN Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag.

KPC-1 (β-Lactamase) is an enzyme that breaks down β-lactam antibiotics, rendering them ineffective. It originates from strains of bacteria, particularly Klebsiella pneumoniae, which are significant sources of hospital-acquired infections. The mode of action involves hydrolyzing the β-lactam ring found in antibiotics such as penicillins and cephalosporins, neutralizing their antibacterial effects. KPC-1 is primarily used in research settings to study bacterial resistance mechanisms and the development of new antimicrobial strategies. Understanding its structure and function is vital for scientists working to combat antibiotic resistance, a major public health threat. Research involving KPC-1 aids in developing novel inhibitors that can restore the efficacy of β-lactam antibiotics against resistant strains. This enzyme is a critical tool for microbiologists and biochemists investigating the intricate dynamics of drug-resistance.

ASAH1 Protein, Human, Recombinant (His & SUMO) is expressed in E.

ST6GAL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

TIPARP Protein, Human, Recombinant (His) is expressed in Baculovirus.

Luciferase enzyme from Photinus pyralis (firefly), which catalyzes the oxidation of firefly luciferin. This reaction depends on the presence of oxygen and ATP and causes the bioluminescence seen in fireflies

Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.

Acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT-1) are two active chitinases expressed in humans.

Toxin A Protein, Clostridioides difficile, Recombinant (His) is expressed in E. coli.

NEK9 Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is Q8TD19.

Cell wall formation.

PDXP Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 33.5 kDa and the accession number is P60487.

WalK Protein, S.

DLST Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

TrkA Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Inositol Polyphosphate 1-Phosphatase (INPP1) is a member of the inositol monophosphatase family.

HDAC6 Protein, Human, Recombinant (His) is expressed in E. coli.

Enolase (phosphopyruvate hydratase, EC 4.2.1.11) is an enzyme that catalyses the following reaction:  2-phospho-D-glycerate ⇌ phosphoenolpyruvate + H2O  One unit of enolase will convert 1.0 μmole of 2-phosphoglycerate to phosphoenolpyruvate per minute.

Essential enzyme in the ergosterol biosynthetic pathway.

NPR1 Protein, Human, Recombinant (His) is expressed in Yeast.

gamma-Glutamyl hydrolase (GGH) regulates intracellular folates and antifolates such as methotrexate (MTX) for proper nucleotide biosynthesis and antifolate-

Glutathione peroxidase (EC 1.11.1.9) is an enzyme that reduces peroxides to limit oxidative damage, by catalyzing the following reaction:  2 GSH + H2O2 → GS-SG + 2 H2O  One unit of glutathione peroxidase will catalyze the conversion of 1.0 µmole of H2O2 per minute at pH 7.0 and 25 °C in the presence of reduced glutathione. Reduced glutahione is available here.

ST2/IL-1 RL1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

p-Fluoro-L-phenylalanine: TH substrate, studies enzyme regulation, binds E. coli L-leucine receptor, KD 0.26μM.

PTPN12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 41.8 kDa and the accession number is AAA36529.1.

TDRD12 Protein, Human, Recombinant (His & Myc) is expressed in E. coli with N-10xHis, C-Myc. The accession number is Q587J7.

MGAT4A Protein, Human, Recombinant (His & Myc) is expressed in HEK293.

A helicase with DNA-dependent ATPase activity.

Phosphoenolpyruvate carboxylase is an enzyme, often found naturally in the cytosol of plant cells, which is derived primarily from various plant species. It plays a crucial role in the photosynthetic process, particularly in C4 and CAM plants. By catalyzing the irreversible carboxylation of phosphoenolpyruvate (PEP) to oxaloacetate, this enzyme facilitates the fixation of carbon dioxide, a vital step in the conversion of carbon dioxide into organic compounds during photosynthesis. The enzyme's mode of action involves the catalytic addition of bicarbonate to PEP, resulting in the formation of oxaloacetate and inorganic phosphate. This biochemical transformation is essential for efficient carbon assimilation, supporting the growth and metabolic functions of plants adapted to arid and high-temperature environments. Applications of phosphoenolpyruvate carboxylase are primarily within the realm of plant biology and agricultural research. Studies utilize this enzyme to understand plant responses to environmental stresses and to develop crops with improved photosynthesis efficiency and resilience. Moreover, its role in carbon metabolism provides insights into optimizing crop yield and enhancing carbon sequestration in the context of environmental sustainability.

Alpha amylase/AMY2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

PTPRT Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells with C-hFc. The accession number is O14522.

IAP Protein, Mouse, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is P24822.

Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis

CBR1 Protein, Human, Recombinant (E.

Carboxypeptidase A2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

KRAS Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E.

PRDX1 Protein, Cricetulus griseus, Recombinant (E. coli, His) is expressed in E. coli.

N/A.

Copper-containing oxidase that catalyzes both the o-hydroxylation of monophenols and the subsequent oxidation of the resulting o-diphenols into reactive o-

One unit will hydrolyse 1.0μmol of 4-nitrophenyl phosphate per minute at 37°C and pH 4.8.  Substrate for enzyme analysis is the 4-nitrophenyl phosphate disodium hexahydrate (EN08508).

HSD17B13 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli with N-10xHis, C-Myc. The accession number is Q8VCR2.

ELP3 Protein, Human, Recombinant (His) is expressed in HEK293. The accession number is Q9H9T3-1.

CK2 alpha/CSNK2A1 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.

TCPTP Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 36.8 kDa and the accession number is P17706-1.

Glucose oxidase is an enzyme thata catalyses the rapid conversion of glucose into non-fermentable gluconic acid in the presence of oxygen (O2). Its used is widely expanded with many applications in the chemical and pharmaceutical industry, food and beverage, clinical studies and biotechnology, among others. It medical diagnosis, glucose oxidase serves as a biosensor for detecting and determining the different levels of glucose in blood samples.

Carbonic Anhydrase 10 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

IL-1R1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Cis-aconitate decarboxylase that catalyzes production of itaconate and is involved in the inhibition of the inflammatory response.

OGT Protein, Human, Recombinant (His & SUMO) is expressed in E.

Human Biliverdin reductase A (BLVRA) is belonged to the Gfo/Idh/MocA family and Biliverdin reductase subfamily.

MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family.

Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline.

FAM20C Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag.

C1 inhibitor Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is

Active on elastin and collagen substrates.

Calcium-regulated non-lysosomal thiol-protease.

Granzyme B Protein, Human, Recombinant (E.