CXCR
Los CXCR son una subfamilia de GPCR que se unen a quimiocinas, pequeñas proteínas de señalización que guían el movimiento de las células inmunitarias hacia los sitios de inflamación, infección o lesión. Los CXCR desempeñan roles cruciales en las respuestas inmunitarias, la metástasis del cáncer y las enfermedades inflamatorias. Los moduladores de CXCR se están investigando por su potencial en el tratamiento de enfermedades autoinmunes, cáncer y afecciones inflamatorias crónicas. En CymitQuimica, ofrecemos una gama de moduladores de CXCR de alta calidad para apoyar su investigación en inmunología, oncología e inflamación.
Productos de "CXCR"
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Pentixafor
CAS:Pentixafor is a peptide that selectively targets the CXCR4 receptor and can be labeled with Gallium-68 (68Ga) for visualization using positron emissionFórmula:C60H80N14O14Pureza:98%Forma y color:SolidPeso molecular:1221.36ITIC-4F
CAS:ITIC-4F: a postfullerene IDTT electron acceptor for high-efficiency PSCs, relevant in binary, ternary, and tandem setups.Fórmula:C94H78F4N4O2S4Pureza:98%Forma y color:SolidPeso molecular:1499.92Navarixin
CAS:Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophilFórmula:C21H23N3O5Pureza:98% - 98.63%Forma y color:SolidPeso molecular:397.42Ref: TM-T7130
1mg40,00€5mg85,00€10mg120,00€25mg210,00€50mg316,00€100mg467,00€500mg1.026,00€1mL*10mM (DMSO)93,00€rac-NBI-74330
CAS:rac-NBI-74330 is an effective and selective CXCR3 antagonist.Fórmula:C32H27F4N5O3Pureza:97.85%Forma y color:SolidPeso molecular:605.58SX-682
CAS:SX-682 is an orally available allosteric inhibitor of CXCR1 and CXCR2.Cost-effective and quality-assured.Fórmula:C19H14BF4N3O4SPureza:98.19% - 99.57%Forma y color:SolidPeso molecular:467.2SB225002
CAS:SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.Fórmula:C13H10BrN3O4Pureza:98.16% - 98.79%Forma y color:SolidPeso molecular:352.14Ref: TM-T1955
5mg50,00€10mg66,00€25mg127,00€50mg225,00€100mg404,00€200mg617,00€500mg938,00€1mL*10mM (DMSO)52,00€Reparixin L-lysine salt
CAS:Reparixin L-lysine salt (Repertaxin L-lysine salt) is an allosteric chemokine receptor 1/2 (CXCR1/2) activation inhibitor.Fórmula:C20H35N3O5SPureza:99%Forma y color:SolidPeso molecular:429.57EMU-116
CAS:EMU-116 is an orally active antagonist of CXCR4, utilized in cancer research.Fórmula:C25H35N5Forma y color:SolidPeso molecular:405.58CXCR4-IN-1
CAS:CXCR4-IN-1 (Example C5), with an IC50 of 20 nM, is a potent inhibitor of CXCR4, applicable for the research of various conditions such as cancer, HIV, diabeticFórmula:C23H32N6Pureza:98%Forma y color:SolidPeso molecular:392.54VUF-11222
CAS:VUF-11222 is an agonist of high affinity non-peptide CXCR3 agonist (pKi = 7.2).Fórmula:C25H31BrINPureza:99.82%Forma y color:SolidPeso molecular:552.33Decursin
CAS:Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.Fórmula:C19H20O5Pureza:100% - 97.22%Forma y color:SolidPeso molecular:328.36Ref: TM-T3S1416
1mg43,00€5mg88,00€10mg119,00€25mg259,00€50mg462,00€100mg662,00€500mg1.359,00€1mL*10mM (DMSO)87,00€CXCR4-IN-2
CXCR4-IN-2 (compound A1), a potent bifunctional fluorinated small molecule, inhibits CXCR4 and exhibits anticancer properties by exerting cytotoxicity (IC 50:Fórmula:C21H20F6N4SPureza:98%Forma y color:SolidPeso molecular:474.47ITIC
CAS:"ITIC, a non-fullerene acceptor with high Tg of 180°C, shows excellent thermal stability and a low glass-crystal transition, plus unique crystallization."Fórmula:C94H82N4O2S4Pureza:98%Forma y color:SolidPeso molecular:1427.96Elubrixin
CAS:Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM).Fórmula:C17H17Cl2FN4O4SPureza:100.00% - 98.65%Forma y color:SolidPeso molecular:463.31Ref: TM-T11179
1mg115,00€5mg249,00€10mg369,00€25mg562,00€50mg787,00€100mg1.054,00€200mg1.406,00€1mL*10mM (DMSO)266,00€NUCC-390 dihydrochloride (1060524-97-1 free base)
NUCC-390 dihydrochloride is selective agonist of small-molecule CXCR4 receptor.Fórmula:C23H35Cl2N5OPureza:98%Forma y color:SolidPeso molecular:468.46AMD 3465 hexahydrobromide
CAS:AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.Fórmula:C24H44Br6N6Pureza:99.39%Forma y color:SolidPeso molecular:896.07Baohuoside I
CAS:Baohuoside I (Icariside-II) is a component of Epimedium koreanum, exhibits anti-inflammatory activity and anti-osteoporosis activities.Fórmula:C27H30O10Pureza:97.02% - 98.85%Forma y color:SolidPeso molecular:514.52Ref: TM-T3396
2mg46,00€5mg66,00€10mg97,00€25mg180,00€50mg283,00€100mg472,00€200mg658,00€1mL*10mM (DMSO)130,00€CXCL-CXCR1/2-IN-1
CAS:CXCL-CXCR1/2-IN-1 is an ELR+CXCL-CXCR1/2 pathway inhibitor with anticancer activity and can be used in the study of cardiovascular disease.Fórmula:C14H8Cl2N4O3SPureza:99.40%Forma y color:SoildPeso molecular:383.21
