TLR
Los receptores tipo Toll (TLR) son una clase de proteínas que desempeñan un papel crítico en el sistema inmunitario innato al reconocer patrones moleculares asociados a patógenos (PAMP) e iniciar respuestas inmunitarias. Los TLR están involucrados en la detección de una amplia gama de patógenos, incluidos bacterias, virus y hongos, y son esenciales para la activación de las vías de señalización inflamatorias. La desregulación de la señalización de los TLR se asocia con enfermedades inflamatorias crónicas, trastornos autoinmunes y cáncer. En CymitQuimica, ofrecemos una variedad de moduladores de TLR de alta calidad para apoyar su investigación en inmunidad innata, inflamación y enfermedades infecciosas.
Productos de "TLR"
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CU-CPT22
CAS:CU-CPT22: first TLR1/2 complex probe, binds at TLR1/2 interface (IC50=0.58μM), inhibits Pam3CSK4 binding (Ki=0.41μM).Fórmula:C19H22O7Pureza:98.66%Forma y color:SolidPeso molecular:362.37Ref: TM-T15020
1mg52,00€2mg70,00€5mg99,00€10mg168,00€25mg313,00€50mg469,00€100mg682,00€200mg938,00€1mL*10mM (DMSO)114,00€BMS-905
CAS:BMS-905 is a potent dual inhibitors of TLR7 and TLR8 with good selectivity against TLR9 and other family members.Fórmula:C23H29N3Pureza:99.85%Forma y color:SoildPeso molecular:347.5SM-324405
CAS:SM-324405 is an agonist of TLR7.Fórmula:C19H23N5O4Pureza:97.83%Forma y color:SolidPeso molecular:385.42Ref: TM-T7860
1mg37,00€5mg78,00€10mg113,00€25mg202,00€50mg324,00€100mg462,00€200mg645,00€1mL*10mM (DMSO)87,00€AXC-715 trihydrochloride
CAS:AXC-715 trihydrochloride is a TLR7/8 agonist used to make PD-L1 adjuvanted antibody immunocouplings.Fórmula:C18H28Cl3N5Pureza:99.74%Forma y color:SolidPeso molecular:420.81Gardiquimod
CAS:Gardiquimod, an imidazoquinoline TLR7 agonist, inhibits HIV-1 in macrophages and PBMCs under 10μM.Fórmula:C17H23N5OPureza:98.02% - 99.47%Forma y color:SolidPeso molecular:313.4CU-CPT17e
CAS:CU-CPT17e is a potent agonist of TLR(TLR3, TLR8, and TLR9).Fórmula:C27H24N2O8Pureza:98.49%Forma y color:SolidPeso molecular:504.49Cholesterol oxidase
CAS:Cholesterol oxidase catalyzes the oxidation and isomerization of cholesterol. ChOx competitively inhibits TLR2 enhance ROS production by macrophages.Forma y color:SolidE6446
CAS:E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling.Fórmula:C27H35N3O3Pureza:98.72%Forma y color:SolidPeso molecular:449.59Rabeximod
CAS:Rabeximod, an immunomodulator, eases autoimmune diseases, inhibits arthritis, and aids brain recovery post-injury by blocking inflammation.Fórmula:C22H24ClN5OPureza:100%Forma y color:SolidPeso molecular:409.91Tomaralimab
CAS:Tomaralimab (OPN-305) is a humanized IgG4 monoclonal antibody targeting TLR2. Tomarlimab is used to study myelodysplastic syndromes (MDS).Pureza:> 95% - SDS-PAGE:95% SEC-HPLC:99.99%Forma y color:LiquidPeso molecular:145.32 kDaTLR7/8 agonist 1 dihydrochloride
CAS:TLR7/8 agonist 1 dihydrochloride (TLR7/8 agonist-5d) is a TLR7/8 agonist which shows prominent immunostimulatory activities.Fórmula:C22H27Cl2N5Pureza:98.33%Forma y color:SolidPeso molecular:432.39MD2-IN-1
CAS:MD2-IN-1 is a Myeloid differentiation protein 2 (MD2) inhibitor with a KD of 189 μM for the recombinant human MD2 (rhMD2).Fórmula:C20H22O6Pureza:99.87%Forma y color:SolidPeso molecular:358.39C29
CAS:C29 inhibits TLR2/1 and TLR2/6 in human cells, but only TLR2/1 in mouse macrophages.Fórmula:C16H15NO4Pureza:96.34% - 97.37%Forma y color:SolidPeso molecular:285.29TLR7 agonist 2
CAS:TLR7 agonist 2 (TLR7-IN-1) is a specific and effective Toll-like Receptor 7 (TLR7) agonist (LEC=0.4 μM).Fórmula:C17H16N6O2Pureza:99.33%Forma y color:SolidPeso molecular:336.35Ref: TM-T4258
1mg157,00€2mg240,00€5mg495,00€10mg717,00€25mg1.111,00€50mg1.501,00€100mg2.023,00€1mL*10mM (DMSO)365,00€Desethyl chloroquine diphosphate
CAS:Desethyl chloroquine diphosphate is the active metabolite of Desethylchloroquine, an inhibitor of TLRs with antiplasmodial activity and inhibition of autophagy.Fórmula:C16H28ClN3O8P2Pureza:99.72%Forma y color:SolidPeso molecular:487.81TLR7/8-IN-1
CAS:TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor, is a valuable compound for autoimmune disease research.Cost-effective and quality-assured.Fórmula:C29H40N8O2Pureza:99.83%Forma y color:SolidPeso molecular:532.68PF-4878691
CAS:PF-4878691 (3M-852A) is an effective and selective Toll-like receptor 7 agonists modelled. It is used to dissociate its antiviral and inflammatory activities.Fórmula:C17H23N5O2SPureza:98.43%Forma y color:SolidPeso molecular:361.46Ref: TM-T16506
1mg48,00€5mg144,00€10mg235,00€25mg512,00€50mg847,00€100mg1.378,00€1mL*10mM (DMSO)159,00€TLR7/8/9-IN-1
CAS:TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.Fórmula:C27H37N3O2Pureza:98.31%Forma y color:SolidPeso molecular:435.6Ref: TM-T39669
1mg52,00€2mg73,00€5mg117,00€10mg188,00€25mg306,00€50mg449,00€100mg610,00€200mg872,00€1mL*10mM (DMSO)170,00€AN3485 Hydrochloride
CAS:AN3485 Hydrochloride is an anti-inflammatory agent and a TLRs inhibitor, reducing ear swelling induced by PMA.Fórmula:C14H14BCl2NO3Pureza:99.76%Forma y color:SolidPeso molecular:325.98ODN 1668
CAS:ODN 1668 is an immunostimulatory class B CpG oligodeoxynucleotide (ODN), used as an agonist for TLR9, and upregulates the level of IgM.Forma y color:SolidPeso molecular:6364.1
