Ras
Las proteínas Ras son pequeñas GTPasas que actúan como interruptores moleculares en la vía de señalización MAPK, controlando el crecimiento, la diferenciación y la supervivencia celular. Ras activado inicia una cascada de señalización que incluye Raf, MEK y ERK, lo que lleva a diversas respuestas celulares. Las mutaciones en los genes Ras son comunes en el cáncer, lo que convierte a Ras en un enfoque importante de la investigación oncológica. En CymitQuimica, ofrecemos una gama de moduladores de Ras para apoyar su investigación en biología del cáncer, transducción de señales y desarrollo terapéutico.
Productos de "Ras"
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XMU-MP-9
CAS:XMU-MP-9, a bifunctional compound, targets the C2 domain of Nedd4-1 and the allosteric site of K-Ras. It enhances the interaction and induces conformational changes within the Nedd4-1/K-Ras complex. Furthermore, XMU-MP-9 facilitates the ubiquitination and degradation of various K-Ras mutants and inhibits the proliferation of cells with these mutants. This compound is useful in cancer research.Fórmula:C19H13ClFN3OSForma y color:SolidPeso molecular:385.84KRAS G12C inhibitor 14
CAS:KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor with an IC 50 of 18 nM [1].Fórmula:C24H19ClF2N4O3Pureza:98%Forma y color:SolidPeso molecular:484.88MCP110
CAS:MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.Fórmula:C33H36N2O3Pureza:97.18%Forma y color:OilPeso molecular:508.65Ref: TM-T24437
1mg37,00€5mg97,00€10mg169,00€25mg291,00€50mg423,00€100mg562,00€500mg1.121,00€1mL*10mM (DMSO)108,00€EHT 1864 2HCl
CAS:EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.Fórmula:C25H29Cl2F3N2O4SPureza:98.39% - 99.42%Forma y color:SolidPeso molecular:581.47Ref: TM-T6483
1mg47,00€5mg92,00€10mg136,00€25mg259,00€50mg472,00€100mg677,00€200mg934,00€1mL*10mM (DMSO)107,00€(E/Z)-ZINC09659342
CAS:(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.Fórmula:C23H15F3N2O4Pureza:95.83%Forma y color:SolidPeso molecular:440.37Ref: TM-T9986
1mg66,00€5mg145,00€10mg221,00€25mg378,00€50mg533,00€100mg718,00€200mg938,00€1mL*10mM (DMSO)160,00€(Rac)-Antineoplaston A10
CAS:Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.Fórmula:C13H14N2O3Pureza:98.41%Forma y color:SolidPeso molecular:246.26Ref: TM-T5379
1mg40,00€5mg88,00€10mg129,00€25mg210,00€50mg311,00€100mg449,00€200mg627,00€1mL*10mM (DMSO)95,00€AZD0022
CAS:AZD0022 is a selective and orally active KRAS G12D inhibitor that displays exposure-dependent pRSK inhibition in a GP2D xenograft model.Fórmula:C34H30F4N6OForma y color:SoildPeso molecular:614.64ML-097
CAS:ML-097 (CID-2160985) is a pan activator of Ras-related GTPasesFórmula:C14H11BrO3Pureza:99.12%Forma y color:SolidPeso molecular:307.139Ref: TM-T21970
5mg65,00€10mg95,00€25mg140,00€50mg202,00€100mg303,00€500mg725,00€1mL*10mM (DMSO)71,00€MRTF-A-IN-2
MRTF-A-IN-2 (compound 16) is an inhibitor of MRTF-A. It effectively suppresses cell proliferation and induces senescence in HCC cells.Forma y color:Odour SolidKRAS G12C inhibitor 59
CAS:KRAS G12C Inhibitor 59 is a compound with anticancer properties.Fórmula:C32H39F6N7O5Pureza:98%Forma y color:SolidPeso molecular:715.69K-Ras-IN-1
CAS:K-Ras-IN-1 is a K-Ras inhibitor.Fórmula:C11H13NOSPureza:98.72%Forma y color:SolidPeso molecular:207.29Ref: TM-T5469
2mg46,00€5mg70,00€10mg101,00€25mg182,00€50mg284,00€100mg424,00€200mg588,00€1mL*10mM (DMSO)77,00€Rhosin hydrochloride
CAS:Rhosin hydrochloride is a specific inhibitor of the RhoA subfamily Rho GTPases.Cost-effective and quality-assured.Fórmula:C20H20Cl2N6OPureza:97.33% - 98.92%Forma y color:SolidPeso molecular:431.318Ref: TM-T16745
1mg159,00€2mg217,00€5mg329,00€10mg472,00€25mg753,00€50mg1.026,00€100mg1.378,00€1mL*10mM (DMSO)363,00€EHop-016
CAS:EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Fórmula:C25H30N6OPureza:100% - 99.86%Forma y color:SolidPeso molecular:430.55Ref: TM-T2427
5mg48,00€10mg73,00€25mg127,00€50mg213,00€100mg334,00€200mg492,00€500mg787,00€1mL*10mM (DMSO)52,00€KRAS inhibitor-33
KRAS inhibitor-33 (compound 115a) is a pyrido[2,3-d]pyrimidine derivative that serves as an effective inhibitor of KRAS, exhibiting an IC50 value of ≤ 100nM.Fórmula:C33H39ClF2N6O3Forma y color:SolidPeso molecular:641.15
