Canal TRP / TRPV
Los canales TRP (Receptor Potencial Transitorio), incluida la subfamilia TRPV, son un grupo de canales iónicos involucrados en diversos procesos sensoriales, como la sensación de temperatura, la percepción del dolor y la osmorregulación. Los canales TRP están ampliamente expresados en diferentes tejidos y desempeñan un papel en las respuestas fisiológicas a estímulos ambientales. Los canales TRPV, en particular, están involucrados en la detección de cambios de temperatura y están implicados en condiciones como el dolor crónico, la inflamación y el cáncer. En CymitQuimica, ofrecemos una gama completa de moduladores de canales TRP/TRPV para apoyar su investigación en biología sensorial, manejo del dolor y transducción de señales.
Productos de "Canal TRP / TRPV"
Ordenar por
ML204
CAS:ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.Fórmula:C15H18N2Pureza:98.1% - 99.72%Forma y color:SolidPeso molecular:226.32Ref: TM-T2298
2mg35,00€5mg50,00€10mg74,00€25mg111,00€50mg145,00€100mg220,00€200mg284,00€500mg467,00€1mL*10mM (DMSO)52,00€ASP7663
CAS:ASP7663 is a TRPA1 Receptor Agonist and exhibiting an abdominal analgesic effect in vivo.Fórmula:C14H14FNO3Pureza:98.61%Forma y color:SolidPeso molecular:263.26GSK3395879
CAS:GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).Fórmula:C20H15F4N3O5SPureza:98%Forma y color:SolidPeso molecular:485.41Mesendogen
CAS:Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7Fórmula:C18H16ClF3N2OSPureza:98.90%Forma y color:SolidPeso molecular:400.85Apcin A HCL
CAS:Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to synthesize the PROTAC CP5V [1].Fórmula:C10H15Cl4N5O2Pureza:99.30%Forma y color:SolidPeso molecular:379.07Ref: TM-T001
1mgA consultar2mg63,00€5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar200mgA consultar500mg2.792,00€Vanilloid receptor antagonist 1
CAS:Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) is a potent vanilloid receptor TRPV1 antagonist.Fórmula:C18H15N3O2Pureza:98.14%Forma y color:SolidPeso molecular:305.33Ref: TM-T9247
1mg99,00€5mg235,00€10mg354,00€25mg602,00€50mg847,00€100mg1.206,00€1mL*10mM (DMSO)47,00€TRPA1-IN-2
CAS:TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM.TRPA1-IN-2 has anti-inflammatory activity.Fórmula:C24H25F3N4OPureza:98.05%Forma y color:SoildPeso molecular:442.48Ref: TM-T77511
1mg85,00€5mg187,00€10mg284,00€25mg482,00€50mg672,00€100mg905,00€200mg1.216,00€1mL*10mM (DMSO)207,00€FEMA-4809
CAS:FEMA-4809 activates TRPM8, the ion channel for cold sensation, and is used as a cooling agent.Fórmula:C17H17N3O2SPureza:99.19%Forma y color:SolidPeso molecular:327.4Ref: TM-T27308
1mg35,00€5mg78,00€10mg116,00€25mg190,00€50mg269,00€100mg383,00€200mg525,00€1mL*10mM (DMSO)88,00€TC-I 2014
CAS:TC-I 2014 shows antiallodynic properties in pain models.Fórmula:C23H19F6N3OPureza:98.75%Forma y color:SolidPeso molecular:467.41Ref: TM-T17006
1mg60,00€5mg127,00€10mg202,00€25mg406,00€50mg655,00€100mg1.074,00€200mg1.454,00€1mL*10mM (DMSO)133,00€AMG9810
CAS:AMG 9810 blocks capsaicin's action on TRPV1; human IC50=24.5 nM, rat IC50=85.6 nM.Fórmula:C21H23NO3Pureza:99.79% - 99.83%Forma y color:SolidPeso molecular:337.41JYL 1421
CAS:JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).Fórmula:C20H26FN3O2S2Pureza:98.83%Forma y color:SolidPeso molecular:423.57Ref: TM-T15634
1mg70,00€5mg187,00€10mg305,00€25mg612,00€50mg938,00€100mg1.491,00€200mg1.985,00€1mL*10mM (DMSO)173,00€RN-1747
CAS:RN-1747: TRPV4 agonist (EC50: human 0.77 μM, mouse 4.0 μM, rat 4.1 μM), TRPM8 antagonist (IC50: 4 μM).Fórmula:C17H18ClN3O4SPureza:99.29%Forma y color:SolidPeso molecular:395.86Ref: TM-T16763
5mg44,00€10mg74,00€25mg126,00€50mg188,00€100mg316,00€200mg452,00€1mL*10mM (DMSO)47,00€HC067047 Hydrochloride(883031-03-6 free base)
CAS:HC-067047 hydrochloride, a TRPV4 antagonist, selectively inhibits human, rat, and mouse currents with IC50s: 486 nM, 133 nM, and 17 nM.Fórmula:C26H29ClF3N3O2Pureza:99.95%Forma y color:SolidPeso molecular:507.98Ref: TM-T4680L
1mg88,00€5mg172,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)217,00€RN9893
CAS:RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.Fórmula:C21H23F3N4O5SPureza:99.89%Forma y color:SolidPeso molecular:500.49D-3263 hydrochloride
CAS:D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.Fórmula:C21H32ClN3O3Pureza:99.85%Forma y color:SolidPeso molecular:409.95PF-4840154
CAS:PF-4840154: potent TrpA1 agonist; EC50 of 97 nM (rat) & 23 nM (human); triggers nociception in mice.Fórmula:C26H38N6O2Pureza:98.48%Forma y color:SolidPeso molecular:466.62A 425619
CAS:A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonistFórmula:C18H14F3N3OPureza:99.35%Forma y color:SolidPeso molecular:345.32Ref: TM-T8562
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)177,00€HC-070
CAS:HC-070 is a TRPC5 and TRPC4 antagonist (IC50 = 9.3 nM and 46 nM).Fórmula:C22H20Cl2N4O4Pureza:97.06%Forma y color:SolidPeso molecular:475.32Ref: TM-T15465
1mg88,00€5mg170,00€10mg259,00€25mg429,00€50mg605,00€100mg815,00€200mg1.093,00€1mL*10mM (DMSO)168,00€A-967079
CAS:A 967079 is a potent, selective, and bioavailable inhibitor of the TRPA1 channel, with IC50 values of 67 and 289 nM for the human and rat isoforms, respectivelyFórmula:C12H14FNOPureza:98.34% - 99.75%Forma y color:SolidPeso molecular:207.24Ononetin
CAS:Ononetin (2',4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone) is a TRPM3 channel blocker(IC50: 0.3 μM).Fórmula:C15H14O4Pureza:98.15%Forma y color:SolidPeso molecular:258.27
