Canal TRP / TRPV
Los canales TRP (Receptor Potencial Transitorio), incluida la subfamilia TRPV, son un grupo de canales iónicos involucrados en diversos procesos sensoriales, como la sensación de temperatura, la percepción del dolor y la osmorregulación. Los canales TRP están ampliamente expresados en diferentes tejidos y desempeñan un papel en las respuestas fisiológicas a estímulos ambientales. Los canales TRPV, en particular, están involucrados en la detección de cambios de temperatura y están implicados en condiciones como el dolor crónico, la inflamación y el cáncer. En CymitQuimica, ofrecemos una gama completa de moduladores de canales TRP/TRPV para apoyar su investigación en biología sensorial, manejo del dolor y transducción de señales.
Productos de "Canal TRP / TRPV"
Ordenar por
PF-05105679
CAS:PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.Fórmula:C26H21FN2O3Pureza:99.82%Forma y color:SolidPeso molecular:428.45Ref: TM-T16483
1mg48,00€2mg65,00€5mg96,00€10mg160,00€25mg305,00€50mg472,00€100mg710,00€200mg938,00€500mg1.444,00€1mL*10mM (DMSO)96,00€Pyr10
CAS:Pyr10, a pyrazole derivative, selectively inhibits TRPC3, not STIM1/Orai1, with IC50 of 0.72 μM in TRPC3-HEK293, and 13.08 μM in BRL-2H3 cells.Fórmula:C18H13F6N3O2SPureza:99.69% - 99.70%Forma y color:SolidPeso molecular:449.37IA-Alkyne
CAS:IA-Alkyne: TRPC agonist, cysteine-reactivity probe, potential in respiratory infection study.Fórmula:C8H12INOPureza:99.76%Forma y color:SolidPeso molecular:265.09Ref: TM-T15543
1mg59,00€5mg126,00€10mg187,00€25mg264,00€50mg329,00€100mg455,00€1mL*10mM (DMSO)120,00€TRPC6-PAM-C20
CAS:TRPC6-PAM-C20, a selective enhancer for TRPC6, boosts calcium in HEK cells and OAG-related platelet clumping, EC50: 2.37μM.Fórmula:C22H21NO4Pureza:98.16%Forma y color:SolidPeso molecular:363.41Pyr3
CAS:Pyr3 selectively blocks TRPC3 channels, reducing Ca2+ influx; it's effective at 700 nM.Fórmula:C16H11Cl3F3N3O3Pureza:99.47%Forma y color:SolidPeso molecular:456.63Ref: TM-T16687
1mg35,00€2mg52,00€5mg77,00€10mg97,00€25mg215,00€50mg363,00€100mg512,00€200mg738,00€500mg1.121,00€1mL*10mM (DMSO)86,00€RN-1734
CAS:RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM,5.9 μM,3.2 μM for hTRPV4, mTRPV4 and rTRPV4,respectively)Fórmula:C14H22Cl2N2O2SPureza:99.1% - 99.30%Forma y color:SolidPeso molecular:353.31SB-366791
CAS:SB-366791 is a new and selective cinnamide TRPV1 antagonist.Fórmula:C16H14ClNO2Pureza:99.12%Forma y color:SolidPeso molecular:287.74TRPM8 antagonist 2
CAS:TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM. TRPM8 antagonist 2 is used in the research of neuropathic pain syndromes.Fórmula:C26H26N2O2Pureza:98.10%Forma y color:SolidPeso molecular:398.5Ref: TM-T5698
1mg35,00€5mg70,00€10mg104,00€25mg170,00€50mg274,00€100mg439,00€200mg632,00€1mL*10mM (DMSO)78,00€NGD-8243
CAS:NGD-8243 (N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine) is a TRPV1 inhibitor and can be used in studies for preventionFórmula:C21H12F6N4Pureza:95.26%Forma y color:SolidPeso molecular:434.34Vocacapsaicin hydrochloride
CAS:Vocacapsaicin hydrochloride (CA-008 hydrochloride) is a non-opioid TRPV1 agonist, a raw material for capsaicin, and is used for pain relief.Fórmula:C26H42ClN3O4Pureza:98.51% - 99.94%Forma y color:SolidPeso molecular:496.08HC-067047
CAS:HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH .Fórmula:C26H28F3N3O2Pureza:99.45% - 99.79%Forma y color:SolidPeso molecular:471.51SAR7334
CAS:SAR7334 (TRCP6-IN-1) is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).Fórmula:C21H22ClN3OPureza:99.62% - 99.71%Forma y color:SolidPeso molecular:367.87Ref: TM-T12849
1mg71,00€5mg160,00€10mg250,00€25mg401,00€50mg567,00€100mg707,00€200mg938,00€1mL*10mM (DMSO)170,00€Asivatrep
CAS:Asivatrep (PAC14028) is a selective and potent antagonist of transient receptor potential vanilloid subtype 1 (TRPV1) for the study of atopic dermatitis.Fórmula:C21H22F5N3O3SPureza:95.13%Forma y color:SolidPeso molecular:491.48WS-12
CAS:WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 nM)Fórmula:C18H27NO2Pureza:99.99%Forma y color:Whitish To White Solid CrystallinePeso molecular:289.41ABT-239
CAS:ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 receptor (H3R) antagonists.Fórmula:C22H22N2OPureza:100%Forma y color:SolidPeso molecular:330.42Ref: TM-T14087
1mg48,00€5mg96,00€10mg160,00€25mg313,00€50mg470,00€100mg660,00€200mg917,00€1mL*10mM (DMSO)96,00€JNJ-28583113
CAS:JNJ-28583113 is a TRPM2 antagonist, inducing phosphorylation of GSK3α and β subunits, protecting cells from oxidative stress-induced cell death.Fórmula:C19H21F3N2O2Pureza:98.57%Forma y color:SolidPeso molecular:366.38Ref: TM-T74779
1mg92,00€5mg215,00€10mg321,00€25mg494,00€50mg856,00€100mg1.478,00€200mg1.931,00€1mL*10mM (DMSO)225,00€PF-04745637
CAS:PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].Fórmula:C27H32ClF3N2O2Pureza:97.91% - 99.3%Forma y color:SolidPeso molecular:509Ref: TM-T64337
1mg73,00€5mg145,00€10mg197,00€25mg333,00€50mg475,00€100mg655,00€200mg882,00€1mL*10mM (DMSO)163,00€MSP3
CAS:MSP3 is an agonist of TRPV1 (EC50 = 0.87 μM) and shows antinociceptive and neuroprotective effects.Fórmula:C16H19NO3SPureza:99.46%Forma y color:SolidPeso molecular:305.39Ref: TM-T28118
2mg34,00€5mg52,00€10mg85,00€25mg170,00€50mg255,00€100mg378,00€200mg533,00€1mL*10mM (DMSO)74,00€M084
CAS:M084 (N-Butyl-1H-benzimidazol-2-amine) is a blocker of TRPC4/5 channel, with antidepressant and anxiolytic effects.Fórmula:C11H15N3Pureza:98.13%Forma y color:SolidPeso molecular:189.26Ref: TM-T8607
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)145,00€MDR-652
CAS:MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1) with Ki value of 11.4 nM and 23.8 nM forFórmula:C22H23ClFN3O2SPureza:99.96%Forma y color:SolidPeso molecular:447.95Ref: TM-T22360
1mg66,00€5mg144,00€10mg205,00€25mg369,00€50mg558,00€100mg800,00€200mg1.074,00€1mL*10mM (DMSO)157,00€
