Canal de sodio
Los canales de sodio son proteínas de membrana esenciales que permiten el paso de iones de sodio (Na+) a través de la membrana celular, generando y propagando señales eléctricas en neuronas, células musculares y otros tejidos excitables. Estos canales son vitales para la iniciación y conducción de potenciales de acción, lo que los hace cruciales en procesos como la transmisión de impulsos nerviosos, la contracción muscular y la función cardíaca. La desregulación de los canales de sodio puede llevar a trastornos neurológicos, arritmias y condiciones de dolor crónico. En CymitQuimica, ofrecemos una variedad de moduladores de canales de sodio para apoyar su investigación en neurobiología, cardiología y manejo del dolor.
Productos de "Canal de sodio"
Ordenar por
Flecainide acetate
CAS:Flecainide acetate (R-818) is a class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias (abnormal fast rhythms of the heart).Fórmula:C19H24F6N2O5Pureza:99.42%Forma y color:SolidPeso molecular:474.39Orphenadrine hydrochloride
CAS:Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.Fórmula:C18H23NO·HClPureza:99.88%Forma y color:Liquid About 5 5 Bitter Numbing Taste (Ntp 1992)Peso molecular:305.85Aneratrigine
CAS:Aneratrigine is a blocker of the sodium channel protein type 9 subunit alpha, utilized in research on neuropathic pain diseases [1].Fórmula:C19H20ClF2N5O2S2Pureza:98%Forma y color:SolidPeso molecular:487.97Riluzole Hydrochloride
CAS:Producto controladoFórmula:C8H5F3N2OS•(HCl)Forma y color:NeatPeso molecular:270.66Amiloride hydrochloride
CAS:Amiloride hydrochloride (Amiloride HCl) 是上皮钠通道和尿激酶型纤溶酶原激活物受体的抑制剂,也是 polycystin-2通道阻断剂。Fórmula:C6H9Cl2N7OPureza:99.72% - 99.95%Forma y color:Physical Description Crystalline Solid Or Very Light Yellow Powder (Ntp 1992)Peso molecular:266.091,2,4-Oxadiazol-3-amine
CAS:Producto controladoApplications 1,2,4-oxadiazol-3-amine (cas# 39512-64-6) is a useful research chemical.Fórmula:C2H3N3OForma y color:NeatPeso molecular:85.062-(1H-1,2,4-Triazol-1-yl)propan-1-ol
CAS:Producto controladoFórmula:C5H9N3OForma y color:NeatPeso molecular:127.15Transcainide
CAS:Transcainide (R 54718), an oral lidocaine-like antiarrhythmic, blocks BTX-activated Na+ channels in heart/muscle.Fórmula:C22H35N3O2Pureza:100%Forma y color:SolidPeso molecular:373.53Articaine hydrochloride
CAS:Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.Fórmula:C13H21ClN2O3SPureza:99.76%Forma y color:White Crystalline PowderPeso molecular:320.84Nav1.7-IN-18
Nav1.7-IN-18 (Compound 31) is a Nav1.7 inhibitor with a Ki value of 4.9 nM and an IC50 of 13 nM, demonstrating analgesic effects in transgenic mice with inherited erythromelalgia (IEM).Fórmula:C30H33Cl2F2NO4Forma y color:SolidPeso molecular:580.49PF-04856264
CAS:PF-04856264 is a Nav1.7 blocker.,modulates intracellular Ca 2+ signaling and chondrocyte secretome, raises the threshold of mechanical pain analgesic.Fórmula:C20H15N5O3S2Forma y color:SolidPeso molecular:437.52,2’-Iminobis(N-(2,6-Dimethylphenyl)acetiamide
CAS:Applications 2,2’-Iminobis(N-(2,6-Dimethylphenyl)acetiamide is an impurity in the synthesis of Lidocaine Hydrochloride (L397800), an anesthetic local agent and antiarrythmic class IB agent. References Duce, R., et al.: J. Pharmacol. Exp. Ther., 179, 580 (1971), Kronberg, G.H., et al.: J. Med. Chem., 16, 739 (1973), Groningsson, K., et al.: Anal. Profiles Drug Subs., 14, 207 (1985), Davies, P.S., et al.: Drugs, 64, 937 (2004),Fórmula:C20H25N3O2Forma y color:NeatPeso molecular:339.43DPI 201-106
CAS:DPI 201-106: cardioselective h1 Na channel inhibitor, enhances heart contraction, blocks potassium and calcium currents.Fórmula:C29H30N4O2Pureza:97.26%Forma y color:SolidPeso molecular:466.57N-Depropylpropafenone
CAS:N-Depropylpropafenone, an active metabolite of Propafenone, is produced through the metabolism by the CYP450 enzyme system (primarily CYP2D6). It functions by blocking sodium ion channels, thereby delaying the depolarization process in myocardial cells and exhibiting antiarrhythmic properties.Fórmula:C18H21NO3Forma y color:SolidPeso molecular:299.36Propoxycaine Hydrochloride
CAS:Producto controladoApplications Propoxycaine is used as a local anaesthetic, an analogue of Procaine (P755150), a local anesthetic of the amino ester group that is primarily used as a topical anesthetic. Procaine is also used to control the pain of intramuscular injection of penicillin as well as in dentistry. References Kania, B.H. et al.: Pol. J. Vet. Sci., 6, 279 (2003); Jussi, L. et al.: Cont. Derm., 60, 150 (2009); Gangarosa, L.P. Sr.: J. Dent. Res., 60, 1471 (1981); Torrens, F. et al.: Int. J. Mol. Sci., 7, 12 (2006);Fórmula:C16H26N2O3·ClHForma y color:NeatPeso molecular:330.85Indenebart
Indenebart is a humanized IgG1λ2 monoclonal antibody targeting SNCA, with HumanIgG1lambda2, Isotype Control serving as the corresponding isotype control.Forma y color:Odour LiquidArticaine-d7 Hydrochloride
CAS:Producto controladoApplications Articaine-d7 Hydrochloride is the labelled form of Articaine Hydrochloride (A777905). Articaine Hydrochloride is the Hydrochloride Salt of Articaine (A777900). Articaine is an amide based short-acting local anesthetic use for regional anaesthesia in day-case settings such arthroscopy, hand, food surgery and in dentistry. References Malamed, S.F., et al.: J. Am. Dent. Assoc., 132, 177 (2001); Luan, F., et al.: Bioorg. Med. Chem., 21, 1870 (2013)Fórmula:C13H13D7N2O3S·HClForma y color:White To Light BeigePeso molecular:327.88Methocarbamol
CAS:Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.Fórmula:C11H15NO5Pureza:99.96%Forma y color:Crystals From Benzene SolidPeso molecular:241.24Bulleyaconitine A
CAS:Bulleyaconitine A, an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.Fórmula:C35H49NO9Pureza:99.56% - 99.76%Forma y color:SolidPeso molecular:627.76
