Glucoquinasa
La glucocinasa (GK) es una enzima que cataliza la fosforilación de la glucosa a glucosa-6-fosfato, un paso crítico en la glucólisis. La GK se expresa predominantemente en el hígado y el páncreas, donde desempeña un papel clave en la regulación de los niveles de glucosa en sangre. Los inhibidores de GK son de interés en el estudio de trastornos metabólicos como la diabetes, ya que pueden modular el metabolismo de la glucosa y la secreción de insulina. En CymitQuimica, ofrecemos inhibidores de glucocinasa para apoyar su investigación en diabetes, metabolismo y desarrollo terapéutico.
Productos de "Glucoquinasa"
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AM-2394
CAS:AM-2394 is an effective and specific Glucokinase agonist (GKA, EC50: 60 nM), which catalyzes the phosphorylation of glucose to glucose-6-phosphate.Fórmula:C22H25N5O4Pureza:99.01% - 99.62%Forma y color:SolidPeso molecular:423.46AP-III-a4
CAS:AP-III-a4 (ENOblock) (ENOblock) is the first nonsubstrate analogue inhibitor of enolase with IC50 of 0.576 μM.Fórmula:C31H43FN8O3Pureza:98.24% - 99.90%Forma y color:SolidPeso molecular:594.72Ref: TM-T6759
1mg51,00€5mg127,00€10mg205,00€25mg378,00€50mg620,00€100mg1.026,00€200mg1.388,00€1mL*10mM (DMSO)166,00€RO-28-1675
CAS:RO-28-1675 is a direct and selective glucokinase activator, the GK/GKRP complex,insulin secretion and type 2 diabetes.Fórmula:C18H22N2O3S2Pureza:99.41%Forma y color:SolidPeso molecular:378.51Ref: TM-T16793
1mg89,00€5mg212,00€10mg365,00€25mg602,00€50mg847,00€100mg1.121,00€200mg1.539,00€1mL*10mM (DMSO)233,00€Globalagliatin
CAS:Globalagliatin (LY2608204) has been used in trials studying the treatment of Diabetes Mellitus, Type 2.Fórmula:C28H37N3O3S3Pureza:98% - 99.41%Forma y color:SolidPeso molecular:559.81Anti-Glucokinase Antibody (5Q209)
Anti-Glucokinase Antibody (5Q209) is a Mouse antibody targeting Glucokinase. Anti-Glucokinase Antibody (5Q209) can be used in ELISA.Forma y color:Odour LiquidGlucokinase activator 8
CAS:Glucokinase activator8 is an activator of glucose kinase (glucokinase).Fórmula:C14H13N3O2SForma y color:SolidPeso molecular:287.337Gcase activator 2
CAS:Gcase activator 2 is a β-glucocerebrosidase activator that induces dimerization of GCase, increases lysosomal substrate metabolism.Fórmula:C21H24N4O2Pureza:99.51% - 99.79%Forma y color:SolidPeso molecular:364.44AZD-1656
CAS:AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2Fórmula:C24H26N6O5Pureza:99.37%Forma y color:SolidPeso molecular:478.5ADP-specific glucokinase
CAS:ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of glucose to glucose-6-phosphate, thereby facilitating glycolysis. This enzyme can activate T cells and enhance the phagocytic activity of macrophages. It is used in research related to metabolic disorders, neurological diseases, and tumors.Forma y color:SolidGlucokinase activator 7
CAS:Glucokinase activator7 is an activator of glucose kinase (Glucokinase) and can be utilized in research on diabetes and hyperglycemia [refer to compound on page 176].Fórmula:C14H13N3O2SForma y color:SolidPeso molecular:287.337Dorzagliatin
CAS:Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.Fórmula:C22H27ClN4O5Pureza:98.52% - 98.67%Forma y color:SolidPeso molecular:462.93Ref: TM-T15159
1mg40,00€2mg52,00€5mg87,00€10mg123,00€25mg240,00€50mg378,00€100mg567,00€1mL*10mM (DMSO)95,00€AP-III-a4 hydrochloride
CAS:AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor that inhibit metastasis and affect glucose homeostasis.Fórmula:C31H44ClFN8O3Pureza:98%Forma y color:SolidPeso molecular:631.18Ref: TM-T6759L
2mg97,00€5mg178,00€10mg286,00€25mg588,00€50mg830,00€100mgA consultar200mgA consultar1mL*10mM (DMSO)248,00€WAY-640509
CAS:WAY-640509 is a glucocerebrosidase inhibitor.Fórmula:C25H23N5O4SPureza:98.59%Forma y color:SolidPeso molecular:489.55Ref: TM-T60048
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€500mg2.157,00€Genz-123346 free base
CAS:Genz 123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1.Fórmula:C24H38N2O4Pureza:99.41%Forma y color:SolidPeso molecular:418.57Cefetrizole
CAS:Ceftezole is an α-Glucosidase inhibitor (IC50: 2.1 μM; Ki: 0.578 μM).Fórmula:C16H15N5O4S3Pureza:98%Forma y color:SolidPeso molecular:437.52Glucosylsphingosine
CAS:Glucosylsphingosine (Lyso-Gb1) is a glycosyl ceramide that accumulates in neurodegenerative disorders and disrupts lysosomal function by activating mTORC1.Fórmula:C24H47NO7Forma y color:SolidPeso molecular:461.63Anti-Glucokinase Antibody (3U461)
Anti-Glucokinase Antibody (3U461) is a Rabbit antibody targeting Glucokinase. Anti-Glucokinase Antibody (3U461) can be used in ELISA.Forma y color:Odour LiquidPF-04991532
CAS:PF-04991532 is an effective, hepatoselective glucokinase activator. It has EC50s of 80 and 100 nM in human and rat, respectively.Fórmula:C18H19F3N4O3Pureza:98%Forma y color:SolidPeso molecular:396.36(1S,2R)-Globalagliatin
CAS:(1S,2R)-Globalagliatin is a highly potent glucokinase (GK) activator for the study of type 2 diabetes.Fórmula:C28H37N3O3S3Pureza:98.31% - 99.00%Forma y color:SoildPeso molecular:559.81PF-04937319
CAS:PF-04937319 activates glucokinase (EC50=154.4μM) with low hypoglycemia risk, researched for type 2 diabetes treatment.Fórmula:C22H20N6O4Pureza:98.61%Forma y color:SolidPeso molecular:432.43
