FAAH
La hidrolasa de amidas de ácidos grasos (FAAH) es una enzima que descompone las amidas de ácidos grasos, incluidos los endocannabinoides como la anandamida. Estos compuestos están involucrados en la regulación del dolor, el estado de ánimo, el apetito y la memoria. La inhibición de la FAAH puede aumentar los niveles de estas moléculas de señalización, ofreciendo beneficios terapéuticos potenciales para el dolor, la ansiedad y las enfermedades neurodegenerativas. En CymitQuimica, ofrecemos una selección de inhibidores de FAAH para apoyar su investigación en neurociencia, manejo del dolor y señalización endocannabinoide.
Productos de "FAAH"
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AM 374
CAS:AM 374 (HDSF), a fatty acid amide hydrolase (FAAH) inhibitor, demonstrates the capacity to inhibit amidase activity, boasting an IC50 value of 13 nM.Fórmula:C16H33FO2SPureza:98.39%Forma y color:SolidPeso molecular:308.5FAAH-IN-1
CAS:FAAH-IN-1 is a fatty acid amide hydrolase (FAAH) inhibitor, with IC50s of 145 nM and 650 nM for rat and human FAAH, respectively.Fórmula:C20H19ClN4OSPureza:98%Forma y color:SolidPeso molecular:398.91N-Benzylpalmitamide
CAS:N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for theFórmula:C23H39NOPureza:97.08% - 99.77%Forma y color:SolidPeso molecular:345.56PF-04457845
CAS:PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).Fórmula:C23H20F3N5O2Pureza:100%Forma y color:SolidPeso molecular:455.43Ref: TM-T4323
2mg35,00€5mg52,00€10mg88,00€25mg163,00€50mg235,00€100mg419,00€200mg545,00€1mL*10mM (DMSO)58,00€LY2183240
CAS:LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM).Fórmula:C17H17N5OPureza:99.26%Forma y color:SolidPeso molecular:307.35JP104
CAS:JP104 is an aryl carbamate that irreversibly inhibits fatty acid amide hydrolase (FAAH) with a pIC50 value of approximately 8 [1].Fórmula:C25H30N2O3Pureza:98%Forma y color:SolidPeso molecular:406.52AA38-3
CAS:AA38-3 (1-Piperidinecarboxylic acid, 4-nitrophenyl ester) inhibites three SHs (ABHD6, ABHD11, and FAAH)Fórmula:C12H14N2O4Pureza:99.56%Forma y color:SolidPeso molecular:250.25URB-597
CAS:URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.Fórmula:C20H22N2O3Pureza:98.24%Forma y color:SolidPeso molecular:338.4N-(3-Methoxybenzyl)Palmitamide
CAS:N-(3-Methoxybenzyl)Palmitamide is a promising FAAH inhibitor, treatment of pain, inflammation and CNS degenerative disorders.Fórmula:C24H41NO2Pureza:99.89%Forma y color:SolidPeso molecular:375.59MAGL-IN-5
CAS:MAGL-IN-5 is a non-selective lipase inhibitor.Fórmula:C18H17N3O5Pureza:99.9%Forma y color:SolidPeso molecular:355.34Ref: TM-T9967
1mg35,00€5mg70,00€10mg96,00€25mg202,00€50mg323,00€100mg512,00€200mg738,00€1mL*10mM (DMSO)81,00€OMDM-1
CAS:OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) is a selective and metabolically stable anandamide cellular uptake (ACU)Fórmula:C27H45NO3Pureza:97.88%Forma y color:SolidPeso molecular:431.65PF 750
CAS:PF 750 (ZINC27647189) is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.Fórmula:C22H23N3OPureza:98.83%Forma y color:SolidPeso molecular:345.44Ref: TM-T16515
2mg39,00€5mg62,00€10mg87,00€25mg187,00€50mg298,00€100mg444,00€200mg635,00€500mg938,00€1mL*10mM (DMSO)67,00€URB937
CAS:URB937 is an inhibitor of FAAH and increases anandamide levels(IC50 : 26.8 nM).Fórmula:C20H22N2O4Pureza:99.55%Forma y color:SolidPeso molecular:354.4FAAH-IN-2
CAS:FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) is a potent inhibitor of FAAH(fatty acid amide hydrolase).Fórmula:C15H11ClFN3O2Pureza:99.18%Forma y color:Tan SolidPeso molecular:319.72MK-4409
CAS:MK-4409, a potent and selective fatty acid amide hydrolase (FAAH) inhibitor, is being investigated for the treatment of inflammatory and neuropathic pain.Fórmula:C22H17ClFN3O2SPureza:99.70% - 99.81%Forma y color:SolidPeso molecular:441.911-Monomyristin
CAS:1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) , a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterialFórmula:C17H34O4Pureza:99.58%Forma y color:SolidPeso molecular:302.45JZL195
CAS:JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.Fórmula:C24H23N3O5Pureza:99.81%Forma y color:SolidPeso molecular:433.46SA57
CAS:SA57 is a potent, selective inhibitor of FAAH(IC50s of 3.2 nM and 1.9 nM for mouse and human FAAH).Fórmula:C17H23ClN2O3Pureza:98%Forma y color:SolidPeso molecular:338.83Isopropyl dodec-11-enylfluorophosphonate
CAS:Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester functioning as a central cannabinoid receptor (CB1) antagonist and exhibitsFórmula:C15H30FO2PPureza:98%Forma y color:SolidPeso molecular:292.37BIA 10-2474
CAS:BIA 10-2474 is a long-acting reversible inhibitor of FAAH that increases levels of the neurotransmitter anandamide in the nervous system.Fórmula:C16H20N4O2Pureza:99.27%Forma y color:SolidPeso molecular:300.36
