PPAR
Los receptores activados por proliferadores de peroxisomas (PPARs) son un grupo de proteínas receptoras nucleares que funcionan como factores de transcripción regulando la expresión de genes involucrados en el metabolismo, particularmente en el almacenamiento de ácidos grasos y el metabolismo de la glucosa. Los inhibidores de PPAR son herramientas importantes para estudiar trastornos metabólicos como la diabetes, la obesidad y las enfermedades cardiovasculares. Estos inhibidores pueden modular el metabolismo de los lípidos, la sensibilidad a la insulina y la inflamación, lo que los convierte en valiosos en la investigación terapéutica. En CymitQuimica, ofrecemos una gama de inhibidores de PPAR para apoyar su investigación en enfermedades metabólicas, endocrinología y desarrollo de fármacos.
Productos de "PPAR"
Ordenar por
Ankaflavin
CAS:Ankaflavin, from red rice fermentation, is a PPARγ agonist with anti-inflammatory properties and selectively kills cancer cells.Fórmula:C23H30O5Pureza:98%Forma y color:SolidPeso molecular:386.48Balaglitazone
CAS:Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.Fórmula:C20H17N3O4SPureza:99.74%Forma y color:SolidPeso molecular:395.43GW0742
CAS:GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).Fórmula:C21H17F4NO3S2Pureza:99.75% - 99.85%Forma y color:SolidPeso molecular:471.49GW1929
CAS:GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ).Fórmula:C30H29N3O4Pureza:98.1% - 98.21%Forma y color:SolidPeso molecular:495.57PPAR agonist 1
CAS:PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.Fórmula:C20H25NO6SPureza:98%Forma y color:SolidPeso molecular:407.48Tetradecylthioacetic acid
CAS:Synthetic fatty acid TTA has β-sulfur, resists β-oxidation, and activates PPARs, especially PPARα.Fórmula:C16H32O2SPureza:≥98%Forma y color:SolidPeso molecular:288.49Ref: TM-T9808
5mg47,00€10mg70,00€25mg111,00€50mg170,00€100mg264,00€200mg398,00€500mg647,00€1mL*10mM (DMSO)50,00€Angeloylgomisin H
CAS:Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.Fórmula:C28H36O8Pureza:97.23% - 99.95%Forma y color:SolidPeso molecular:500.58Ref: TM-TN1018
1mg55,00€5mg117,00€10mg182,00€25mg306,00€50mg444,00€100mg610,00€1mL*10mM (DMSO)158,00€Bocidelpar
CAS:Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells.Fórmula:C25H27F3N2O3Pureza:98.05%Forma y color:SolidPeso molecular:460.49Ref: TM-T39516
1mg120,00€5mg274,00€10mg411,00€25mg742,00€50mg1.111,00€100mg1.549,00€1mL*10mM (DMSO)279,00€Anti-NASH agent 1
CAS:Anti-NASH Agent 1 (Compound 3d), derived from Elafibranor, serves as a strong PPAR-α/δ agonist aimed at treating nonalcoholic steatohepatitis (NASH).Fórmula:C26H33NO4Pureza:98%Forma y color:SolidPeso molecular:423.54GSK0660
CAS:GSK0660 is an antagonist and inverse agonist of PPARβ/δ.Fórmula:C19H18N2O5S2Pureza:100% - ≥95%Forma y color:SolidPeso molecular:418.49Ref: TM-T2674
2mg47,00€5mg69,00€10mg104,00€25mg185,00€50mg369,00€100mg548,00€500mg1.198,00€1mL*10mM (DMSO)69,00€Fenofibrate
CAS:Fenofibrate (Lipanthyl) is a PPARα agonist. Fenofibrate inhibits cytochrome P450 isoforms. Fenofibrate exhibits antihyperlipidemic activity. Cost-effective and quality-assured.Fórmula:C20H21ClO4Pureza:99.13% - 99.95%Forma y color:Crystals From Isopropanol SolidPeso molecular:360.83SP4e
SP4e is a PPAR-γ activator.SP4e was effective in decreasing blood glucose, total cholesterol, triglycerides and LDL levels and increasing HDL levels.Fórmula:C22H17ClN2O2S2Pureza:99.79%Forma y color:SoildPeso molecular:440.97Retinoic acid
CAS:Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.Fórmula:C20H28O2Pureza:97.21% - 99.6%Forma y color:Yellow-Orange PowderPeso molecular:300.44GQ-16
CAS:GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.Fórmula:C19H16BrNO3SPureza:99.12%Forma y color:SolidPeso molecular:418.3Lonazolac
CAS:Lonazolac is a nonsteroidal anti-inflammatory drug[1].Fórmula:C17H13ClN2O2Pureza:99.40%Forma y color:SolidPeso molecular:312.75Ref: TM-T50025
5mg57,00€10mg86,00€25mg131,00€50mg188,00€100mg284,00€200mg426,00€1mL*10mM (DMSO)74,00€Cevoglitazar
CAS:Cevoglitazar (LBM-642) is a PPARɑ agonist and PPARγ agonist. Cevoglitazar potently reduces food intake and body weight in obese mice and cynomolgus monkeys.Fórmula:C27H21F3N2O6SPureza:97.39%Forma y color:SolidPeso molecular:558.53Mifobate
CAS:Mifobate (SR-202) 是一种有效且特异性的 PPARγ拮抗剂,可选择性抑制噻唑烷二酮 (TZD) 诱导的 PPARγ 转录活性,IC50为140 μM,具有抗肥胖和抗糖尿病作用。Fórmula:C11H17ClO7P2Pureza:99.12%Forma y color:SolidPeso molecular:358.65Ref: TM-T16074
1mg52,00€5mg111,00€10mg180,00€25mg303,00€50mg449,00€100mg645,00€1mL*10mM (DMSO)124,00€Cinnamyl alcohol
CAS:Cinnamyl alcohol (Styryl Carbinol) readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.Fórmula:C9H10OPureza:99.00%Forma y color:Colourless LiquidPeso molecular:134.18Fonadelpar
CAS:Fonadelpar is an agonist of PPARδ. It also is used in the research of neuroparalytic keratopathy.Fórmula:C25H23F3N2O4SPureza:98%Forma y color:SolidPeso molecular:504.52GW6471
CAS:GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.Fórmula:C35H36F3N3O4Pureza:98.23% - 99.55%Forma y color:SolidPeso molecular:619.67Ref: TM-T8486
1mg38,00€5mg80,00€10mg105,00€25mg215,00€50mg426,00€100mg623,00€500mg1.293,00€1mL*10mM (DMSO)120,00€
