PPAR
Los receptores activados por proliferadores de peroxisomas (PPARs) son un grupo de proteínas receptoras nucleares que funcionan como factores de transcripción regulando la expresión de genes involucrados en el metabolismo, particularmente en el almacenamiento de ácidos grasos y el metabolismo de la glucosa. Los inhibidores de PPAR son herramientas importantes para estudiar trastornos metabólicos como la diabetes, la obesidad y las enfermedades cardiovasculares. Estos inhibidores pueden modular el metabolismo de los lípidos, la sensibilidad a la insulina y la inflamación, lo que los convierte en valiosos en la investigación terapéutica. En CymitQuimica, ofrecemos una gama de inhibidores de PPAR para apoyar su investigación en enfermedades metabólicas, endocrinología y desarrollo de fármacos.
Productos de "PPAR"
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CAS:Bisphenol a diglycidyl ether is a Standardized Chemical Allergen.Fórmula:C21H24O4Pureza:85.3%Forma y color:Sticky Bisphenol A Diglycidyl Ether Is An Odorless Yellowish Brown Liquid Sinks In Water (Uscg 1999)Peso molecular:340.41Pioglitazone hydrochloride
CAS:Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplasticFórmula:C19H20N2O3S·HClPureza:100% - 99.66%Forma y color:White Crystals Or Crystalline PowderPeso molecular:392.9PPARδ agonist 9
CAS:PPARδ agonist 9 (compound 21), with an EC50 of 3.6 nM, is effective in vivo, decreasing serum MCP-1 concentrations in mice and markedly reducing atheroscleroticFórmula:C26H28ClF3N4O3SPureza:98%Forma y color:SolidPeso molecular:569.04Elafibranor
CAS:Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) withFórmula:C22H24O4SPureza:99.5% - 99.55%Forma y color:SolidPeso molecular:384.49Ref: TM-T4408
2mg35,00€5mg52,00€10mg80,00€25mg135,00€50mg215,00€100mg354,00€500mg825,00€1mL*10mM (DMSO)57,00€Gemfibrozil
CAS:Gemfibrozil, a fibric acid derivative, stimulates PPARalpha, boosts fatty acid oxidation, LPL, lowers VLDL-C, apoC-III, and raises HDL-C.Fórmula:C15H22O3Pureza:99.53% - 99.88%Forma y color:Crystals From Hexane SolidPeso molecular:250.33Icariin
CAS:Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.Fórmula:C33H40O15Pureza:97.82% - 98.49%Forma y color:SolidPeso molecular:676.66BAY-4931
CAS:BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.Fórmula:C22H16ClN3O4Pureza:99.47%Forma y color:SoildPeso molecular:421.83Ref: TM-T67933
1mg40,00€5mg88,00€10mg126,00€25mg274,00€50mg432,00€100mg638,00€500mg1.359,00€1mL*10mM (DMSO)97,00€Inolitazone dihydrochloride
CAS:Inolitazone dihydrochloride is an effective, high-affinity PPARγ agonist; its biological activity is dependent on PPARγ (IC50:0.8 nM) to inhibit cell growth.Fórmula:C27H28Cl2N4O4SForma y color:SolidPeso molecular:575.51Licarin B
CAS:1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity.Fórmula:C20H20O4Pureza:100% - ≥95%Forma y color:SolidPeso molecular:324.37SC-236
CAS:SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).Fórmula:C16H11ClF3N3O2SPureza:99.74%Forma y color:SolidPeso molecular:401.79Anandamide
CAS:Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but alsoFórmula:C22H37NO2Pureza:98.76% - 99.22%Forma y color:Light Yellow OilPeso molecular:347.53Ref: TM-T14046
1mg35,00€2mg49,00€5mg74,00€10mg131,00€25mg246,00€50mg366,00€100mg538,00€200mg752,00€1mL*10mM (DMSO)81,00€Reglitazar
CAS:Reglitazar, a dual PPARα/γ agonist, enhances insulin signaling, reduces insulin resistance, and lowers hypertriglyceridemia in obese rats.Fórmula:C22H20N2O5Pureza:97.07% - 98.72%Forma y color:SolidPeso molecular:392.4Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Fórmula:C13H26N2O4Pureza:99.35% - 99.73%Forma y color:SolidPeso molecular:274.36Oroxin A
CAS:Oroxin A (Baicalein 7-O-glucoside) has antitussive and expectorant effects.Fórmula:C21H20O10Pureza:98.05% - 99.74%Forma y color:SolidPeso molecular:432.38Ref: TM-T5S0788
1mg43,00€5mg87,00€10mg135,00€25mg224,00€50mg369,00€100mg509,00€500mg1.093,00€1mL*10mM (DMSO)95,00€(±)-CBCQ
CAS:(±)-CBCQ, an oxidation product of cannabidiol, exhibits an EC50 value of 14.7 μM for the activation of peroxisome proliferator-activated receptor γ (PPAR-γ).Fórmula:C21H28O3Forma y color:SolidPeso molecular:328.455-Aminosalicylic Acid
CAS:5-ASA, an anti-inflammatory salicylate, treats inflammatory bowel disease, active part of sulphalazine.Fórmula:C7H7NO3Pureza:98.88% - 99.98%Forma y color:Purplish-Tan Solid PowderPeso molecular:153.14Fenofibric acid
CAS:Fenofibric acid (FNF acid) is the active form of fenofibrate, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity.Fórmula:C17H15ClO4Pureza:99.36%Forma y color:White Or Almost White Crystalline PowderPeso molecular:318.75Aleglitazar
CAS:Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively.Fórmula:C24H23NO5SPureza:99.42%Forma y color:SolidPeso molecular:437.51Ref: TM-T14176
1mg245,00€5mg562,00€10mg758,00€25mg1.159,00€50mg1.568,00€100mg2.110,00€1mL*10mM (DMSO)568,00€PPARγ-IN-2
CAS:"PPARγ-IN-2 (Compound 5a), a PPARγ inhibitor, exhibits an EC50 of 0.106 μM in inhibiting TG accumulation in 3T3-L1 preadipocytes.Fórmula:C19H21N5OPureza:98%Forma y color:SolidPeso molecular:335.4Tesaglitazar
CAS:Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARαFórmula:C20H24O7SPureza:99.89%Forma y color:SolidPeso molecular:408.47Ref: TM-T17044
1mg46,00€5mg87,00€10mg137,00€25mg255,00€50mg472,00€100mg687,00€500mg1.444,00€1mL*10mM (DMSO)106,00€
