PPAR
Los receptores activados por proliferadores de peroxisomas (PPARs) son un grupo de proteínas receptoras nucleares que funcionan como factores de transcripción regulando la expresión de genes involucrados en el metabolismo, particularmente en el almacenamiento de ácidos grasos y el metabolismo de la glucosa. Los inhibidores de PPAR son herramientas importantes para estudiar trastornos metabólicos como la diabetes, la obesidad y las enfermedades cardiovasculares. Estos inhibidores pueden modular el metabolismo de los lípidos, la sensibilidad a la insulina y la inflamación, lo que los convierte en valiosos en la investigación terapéutica. En CymitQuimica, ofrecemos una gama de inhibidores de PPAR para apoyar su investigación en enfermedades metabólicas, endocrinología y desarrollo de fármacos.
Productos de "PPAR"
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Fisetin
CAS:Fisetin belongs to a group of natural flavonols with anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective effects. Cost effective and quality assured.Fórmula:C15H10O6Pureza:94.14% - 98.31%Forma y color:Yellow To Brown Crystalline PowderPeso molecular:286.24PPARγ agonist 16
CAS:PPARγ agonist16 (Compound 4G) is a PPARγ agonist that competitively binds to the ligand-binding domain (LBD) of PPARγ with an IC50 of 1790 nM. It reduces ear swelling in mouse models and exhibits antihyperglycemic activity in mice with Streptozotocin-induced diabetes.Fórmula:C19H14BrNO4SForma y color:SolidPeso molecular:432.29β-Amyrone
CAS:beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM.Fórmula:C30H48OPureza:99.55%Forma y color:SolidPeso molecular:424.7Chiglitazar
CAS:Chiglitazar is a PPAR α/γ/δ agonist and insulin sensitizer used in the treatment of type 2 diabetes mellitus , anti-inflammatory and anti-fibrotic.Fórmula:C36H29FN2O4Forma y color:SolidPeso molecular:572.63Dazmegrel
CAS:Dazmegrel (UK 38,485) is a thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy.Fórmula:C16H17N3O2Pureza:99.20%Forma y color:SolidPeso molecular:283.33Suksdorfin
CAS:Suksdorfin has hypoglycemic effects and activates PPARγ, which promotes insulin-dependent glucose uptake by adipocytes and can be used to study obesity .Fórmula:C21H24O7Pureza:98.43%Forma y color:SolidPeso molecular:388.41Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-
CAS:Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM.Fórmula:C24H23NO5SPureza:99.18%Forma y color:SoildPeso molecular:437.51Ref: TM-T63898
1mg185,00€5mg426,00€10mg627,00€25mg938,00€50mg1.320,00€100mg1.786,00€1mL*10mM (DMSO)472,00€Troglitazone
CAS:Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Fórmula:C24H27NO5SPureza:98% - 99.62%Forma y color:Yellow SolidPeso molecular:441.54Ref: TM-T3170
2mg42,00€5mg62,00€10mg88,00€25mg172,00€50mg305,00€100mg558,00€500mg1.169,00€1mL*10mM (DMSO)85,00€Convallatoxin
CAS:Convallatoxin is a natural product.Fórmula:C29H42O10Pureza:99.27%Forma y color:Prisms From Methanol + Ether SolidPeso molecular:550.64Oleoylethanolamide
CAS:Oleoylethanolamide (N-Oleoylethanolamide) is a high affinity endogenous agonist of PPAR-α.Fórmula:C20H39NO2Pureza:99.98%Forma y color:SolidPeso molecular:325.53Ref: TM-T12296
2mg35,00€5mg52,00€10mg80,00€25mg145,00€50mg250,00€100mg376,00€200mg550,00€1mL*10mM (DMSO)58,00€Glabridin
CAS:Glabridin aids in diabetes by reducing inflammation and glucose levels and may prevent liver cancer spread.Fórmula:C20H20O4Pureza:99.78% - 99.99%Forma y color:Light Yellow Powder Insoluble In WaterPeso molecular:324.37CGS 15435
CAS:CGS 15435: potent TxA2 synthase inhibitor, IC50=1 nM; less selective for PGI2 synthase, COX, and liposynthase.Fórmula:C20H21ClN2O2Pureza:99.63%Forma y color:SolidPeso molecular:356.85Seladelpar
CAS:Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.Fórmula:C21H23F3O5SPureza:99.07% - 99.20%Forma y color:SolidPeso molecular:444.46Mavodelpar free base
CAS:Mavodelpar free acid (REN001 free acid) is an selective agonist of PPARδ.Fórmula:C31H30FNO5Pureza:98%Forma y color:SolidPeso molecular:515.57GW590735
CAS:GW590735: PPARα agonist, EC50=4 nM, >500x selective over PPARδ/γ, for dyslipidemia research.Fórmula:C23H21F3N2O4SPureza:99.12%Forma y color:SolidPeso molecular:478.48Ref: TM-T9766
1mg95,00€5mg202,00€10mg298,00€25mg507,00€50mg730,00€100mg1.026,00€1mL*10mM (DMSO)213,00€GW7647
CAS:GW 7647 is an effective and highly selective PPARα agonist. GW 7647 can reduce the production of nitric oxide in macrophages. Cost-effective and quality-assured.Fórmula:C29H46N2O3SPureza:99.30% - 99.34%Forma y color:SolidPeso molecular:502.75Rosiglitazone maleate
CAS:Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.Fórmula:C22H23N3O7SPureza:99.33% - 99.51%Forma y color:Off-White SolidPeso molecular:473.5FH535
CAS:FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.Fórmula:C13H10Cl2N2O4SPureza:98.25% - 99.5%Forma y color:SolidPeso molecular:361.2Ref: TM-T2413
5mg38,00€10mg57,00€25mg94,00€50mg164,00€100mg274,00€200mg404,00€500mg653,00€1mL*10mM (DMSO)64,00€Raspberry ketone
CAS:1.Fórmula:C10H12O2Pureza:99.84% - 99.89%Forma y color:White Solid CrystallinePeso molecular:164.2PPARα-MO-1
CAS:PPARα-MO-1 is a potent modulator of PPARα.Fórmula:C27H37NO5Pureza:98%Forma y color:SolidPeso molecular:455.59
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