PPAR
Los receptores activados por proliferadores de peroxisomas (PPARs) son un grupo de proteínas receptoras nucleares que funcionan como factores de transcripción regulando la expresión de genes involucrados en el metabolismo, particularmente en el almacenamiento de ácidos grasos y el metabolismo de la glucosa. Los inhibidores de PPAR son herramientas importantes para estudiar trastornos metabólicos como la diabetes, la obesidad y las enfermedades cardiovasculares. Estos inhibidores pueden modular el metabolismo de los lípidos, la sensibilidad a la insulina y la inflamación, lo que los convierte en valiosos en la investigación terapéutica. En CymitQuimica, ofrecemos una gama de inhibidores de PPAR para apoyar su investigación en enfermedades metabólicas, endocrinología y desarrollo de fármacos.
Productos de "PPAR"
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EPI-001
CAS:EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.Fórmula:C21H27ClO5Pureza:99% - 99.28%Forma y color:SolidPeso molecular:394.89Ref: TM-T6829
2mg35,00€5mg50,00€10mg77,00€25mg127,00€50mg202,00€100mg303,00€200mg449,00€1mL*10mM (DMSO)51,00€LCB-2853
CAS:LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects.Fórmula:C21H24ClNO4SPureza:97.15%Forma y color:SolidPeso molecular:421.94Bilobetin
CAS:Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.Fórmula:C31H20O10Pureza:97.74% - 99.73%Forma y color:SolidPeso molecular:552.48Ref: TM-T4S2128
1mg47,00€2mg70,00€5mg144,00€10mg250,00€25mg424,00€50mg613,00€100mg843,00€1mL*10mM (DMSO)187,00€Ginsenoside Rh1
CAS:Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.Fórmula:C36H62O9Pureza:99% - 99.77%Forma y color:SolidPeso molecular:638.87(E/Z)-Elafibranor
CAS:GFT505 (Elafibranor) (Elafibranor) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively.Fórmula:C22H24O4SPureza:98.36%Forma y color:SolidPeso molecular:384.49Amezalpat
CAS:Amezalpat is a PPARα antagonist with an IC50 of 58 nM [nanomolar]. Amezalpat also exhibits antitumor activity.Fórmula:C34H41N3O4Forma y color:SolidPeso molecular:555.70713-Oxo-9E,11E-octadecadienoic acid
CAS:13-Oxo-9E,11E-octadecadienoic acid from tomato juice, an isomer of 9-oxo-ODA, activates PPARα and lowers triglycerides in diabetic mice.Fórmula:C18H30O3Pureza:98%Forma y color:SolidPeso molecular:294.43Methyl oleanonate
CAS:3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties.Fórmula:C31H48O3Pureza:98.99%Forma y color:SolidPeso molecular:468.71Pparδ agonist 2
CAS:Pparδ agonist 2 is an agonist of PPARδ.Fórmula:C20H18F3N3O3SPureza:98%Forma y color:SolidPeso molecular:437.44Edaglitazone
CAS:Edaglitazone (R-483) is a PPARγ agonist with antiplatelet activity that can be used in studies of diabetes and obesity.Fórmula:C24H20N2O4S2Pureza:98%Forma y color:SolidPeso molecular:464.56Peliglitazar racemate
CAS:Peliglitazar racemate(BMS 426707-01 racemate) is the racemate of Peliglitazar.Peliglitazar racemate may be used as a potential antidiabetic and anti-obesityFórmula:C30H30N2O7Pureza:97.75%Forma y color:SolidPeso molecular:530.57Gypenoside XLIX
CAS:Extracted from whole herb of Gynostemsma pentaphyllum(Thunb.)Mak.;Store the product in sealed, cool and dry conditionFórmula:C52H86O21Pureza:99.59% - 99.78%Forma y color:SolidPeso molecular:1047.23KD-3010
CAS:KD-3010 (Kalypsys) is an orally active potent and selective PPARδ agonist for the study of liver injury.Fórmula:C30H33F3N2O8S2Pureza:99.61%Forma y color:SolidPeso molecular:670.72EHP-101
CAS:EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.Fórmula:C28H35NO3Pureza:99.22%Forma y color:SolidPeso molecular:433.58Ref: TM-T13289
1mg107,00€5mg227,00€10mg378,00€25mg620,00€50mg868,00€100mg1.169,00€1mL*10mM (DMSO)250,00€PPARγ-IN-3
PPARγ-IN-3 (compound 9ga), a potent and orally active PPARγ inhibitor, effectively reduces triglyceride (TG) accumulation and exhibits low cytotoxicity. Additionally, it prevents excessive body weight gain, lessens fat and liver mass, and decreases lipid accumulation in both the liver and blood. PPARγ-IN-3 holds promise for research into diet-induced obesity.Fórmula:C23H28FN7O3Forma y color:SolidPeso molecular:469.51GW 9578
CAS:GW 9578 is a PPARα agonist with potent lipid-lowering activity for the study of psoriasis, arthritis, alopecia, asthma and type I diabetes.Fórmula:C26H34F2N2O3SPureza:98%Forma y color:SolidPeso molecular:492.62PPARγ modulator-2
CAS:PPARγmodulator-2 (Compound (R)-2n) is a reversible modulator of PPARγ, inhibiting the PPARγ ligand-binding domain (LBD) with an IC50 of 41 nM. It helps lower blood glucose levels, improves glucose tolerance and insulin sensitivity, and demonstrates antidiabetic activity in db/db mouse models.Fórmula:C26H21NO7S3SeForma y color:SolidPeso molecular:634.6Ciprofibrate
CAS:Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.Fórmula:C13H14Cl2O3Pureza:100% - 99.95%Forma y color:White Or Almost White Crystalline PowderPeso molecular:289.15GW9662
CAS:GW9662 (TIMTEC-BB SBB006523) is a specific PPARγ antagonist, with 100 to 1000-fold functional selectivity for PPARγ than PPARα/δ in cells.Fórmula:C13H9ClN2O3Pureza:98% - 99.95%Forma y color:Off-White SolidPeso molecular:276.68Pioglitazone
CAS:Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes.Fórmula:C19H20N2O3SPureza:95% - 99.57%Forma y color:White PowderPeso molecular:356.44
