Receptor 5-HT
Los receptores 5-HT, también conocidos como receptores de serotonina, son un grupo de receptores acoplados a proteínas G (GPCR) que median los efectos de la serotonina, un neurotransmisor involucrado en la regulación del estado de ánimo, la ansiedad, el sueño, el apetito y otros procesos fisiológicos. Estos receptores se dividen en varios subtipos, cada uno con funciones y propiedades farmacológicas distintas. Los moduladores de los receptores 5-HT se estudian ampliamente por su papel en el tratamiento de la depresión, los trastornos de ansiedad y otras afecciones neuropsiquiátricas. En CymitQuimica, ofrecemos una gama de moduladores de receptores 5-HT de alta calidad para apoyar su investigación en neurofarmacología, trastornos del estado de ánimo y señalización GPCR.
Productos de "Receptor 5-HT"
Ordenar por
Pizotifen Malate
CAS:Pizotifen Malate (BC-105 malate), a highly selective 5-HT receptor blocking agent, is a drug based on benzocycloheptane.Fórmula:C19H21NS·C4H6O5Pureza:100%Forma y color:SolidPeso molecular:429.53Repinotan
CAS:Repinotan (BAY x 3702 free base) is a 5-HT1A receptor agonist used in acute ischemic stroke studies.Fórmula:C21H24N2O4SPureza:99%Forma y color:SolidPeso molecular:400.49Gentisein
CAS:Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7Fórmula:C13H8O5Pureza:96.74%Forma y color:SolidPeso molecular:244.2(Rac)-Norcisapride
CAS:Norcisapride, a 5-HT3 and 5-HT4 agonist, treats GI, orofacial, and ENT disorders.Fórmula:C14H20ClN3O3Pureza:99.13%Forma y color:SoildPeso molecular:313.78(S)-Amisulpride
CAS:(S)-Amisulpride ((S) Amisulpride) (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist.Fórmula:C17H27N3O4SPureza:98.38%Forma y color:SolidPeso molecular:369.48Ref: TM-T26375
1mg50,00€2mg71,00€5mg114,00€10mg178,00€25mg340,00€50mg538,00€100mg730,00€200mg938,00€1mL*10mM (DMSO)126,00€AAZ-A 154 hydrobromide
CAS:AAZ-A 154 hydrobromide is a selective, competitive, non-hallucinogenic 5-HT2AR antagonist. It promotes neuronal growth in rodents and yields enduring beneficial behavioral effects.Fórmula:C14H21BrN2OForma y color:SolidPeso molecular:313.23Ondansetron hydrochloride dihydrate
CAS:Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist,which has reported anxiolytic and neuroleptic properties.Fórmula:C18H19N3O·HCl·2H2OPureza:99.92%Forma y color:White Crystal PowderPeso molecular:365.86SB 243213 hydrochloride
CAS:SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8).ItFórmula:C22H20ClF3N4O2Pureza:98%Forma y color:SolidPeso molecular:464.87Ipsapirone
CAS:Ipsapirone is a partial agonist of 5-HT1A receptor and produces an inhibitory effect on 5-HT2 and the α1-adrenergic function at high doses.Fórmula:C19H23N5O3SPureza:99.01%Forma y color:SolidPeso molecular:401.485-HT1A modulator 4
CAS:5-HT1A modulator 4 (Compound 1) is a ligand for the 5-HT receptor, with Ki values of 2.18 μM for 5-HT1A and 19.7 μM for 5-HT2A.Fórmula:C9H14N4Forma y color:SolidPeso molecular:178.234SB-200646A
CAS:SB-200646A: oral 5-HT2B/2C antagonist; higher affinity than 5-HT2A (pKi: 7.5, 6.9 vs 5.2); anxiolytic with in vivo effects.Fórmula:C15H15ClN4OPureza:98%Forma y color:SolidPeso molecular:302.76Adatanserin
CAS:Adatanserin (WY 50324) is a mixed 5-HT1A receptor partial agonist and a 5-HT2A and 5-HT2C receptor antagonist.Fórmula:C21H31N5OPureza:99.17%Forma y color:SolidPeso molecular:369.5ST1936
CAS:ST1936 (ST 1936 oxalate) is a 5-HT6 receptor agonist that stimulates cAMP, Ca2+, ERK1/2, and Fyn kinases by fully activating cloned human 5-HT6 receptors.Fórmula:C13H17ClN2Pureza:98.00%Forma y color:SolidPeso molecular:236.74Ref: TM-T23396
1mg47,00€5mg117,00€10mg188,00€25mg334,00€50mg497,00€100mg720,00€200mg1.008,00€1mL*10mM (DMSO)130,00€Cyproheptadine hydrochloride
CAS:Cyproheptadine hydrochloride (Periactin hydrochloride) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist.Fórmula:C21H21N·HClPureza:99.88% - 99.97%Forma y color:SolidPeso molecular:323.86Tropanserin
CAS:Tropanserin (MDL 72422) is a 5-hydroxytryptamine receptor antagonist with anxiolytic activity that is used to treat depression and cognitive impairment.Fórmula:C17H23NO2Pureza:99.74%Forma y color:SolidPeso molecular:273.37Sarizotan 2HCl
CAS:Sarizotan 2HCl is an hERG channel inhibitor and 5-hydroxytryptamine 5-HT1A receptor agonist with potential antidepressant effects for the study of Parkinsonian movement disorders.Fórmula:C22H23Cl2FN2OPureza:98.83%Forma y color:SoildPeso molecular:421.345-HT2C agonist-3 free base
CAS:5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-Fórmula:C19H22FNO2Pureza:98%Forma y color:SolidPeso molecular:315.38Sulamserod hydrochloride
CAS:Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.Fórmula:C19H29Cl2N3O5SForma y color:SolidPeso molecular:482.42LY 344864
CAS:LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.Fórmula:C21H22FN3OPureza:98%Forma y color:SolidPeso molecular:351.42γ-Mangostin
CAS:Gamma-Mangostin (Normangostin) has free radical scavenging activity, and antiproliferative and apoptotic activity. Gamma-Mangostin is an antihypertensive agent.Fórmula:C23H24O6Pureza:98.55% - 99.08%Forma y color:SolidPeso molecular:396.43WAY 163909
CAS:WAY 163909 is an effective and selective agonist of the 5-HT(2C) receptor (Ki: 10.5±1.1 nM).Fórmula:C14H18N2Pureza:98%Forma y color:SolidPeso molecular:214.315-HT7 agonist 1
CAS:5-HT7 agonist 1 (4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole) is a selective agonist of 5-HT7 (IC50 = 222.93 nM).Fórmula:C19H20ClN3Pureza:98.61%Forma y color:SolidPeso molecular:325.84Ref: TM-T10170
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€1mL*10mM (DMSO)255,00€YM-31636 free base
CAS:YM-31636 (free base) is an orally active, potent, and selective agonist of the 5-HT3 receptor with a pKi value of 9.67. This compound induces contraction in isolated guinea pig distal colon and provokes tachycardia in isolated guinea pig right atrium, demonstrating a relative intrinsic activity of about 0.23. YM-31636 (free base) holds potential for research in constipation management.Fórmula:C14H11N3SForma y color:SolidPeso molecular:253.325-HT2 agonist-1 free base
CAS:Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,Fórmula:C19H22N2O2Pureza:98%Forma y color:SolidPeso molecular:310.39Thioridazine hydrochloride
CAS:Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Fórmula:C21H27ClN2S2Pureza:99.55% - 99.55%Forma y color:White To Off-White SolidPeso molecular:407.0425N-NBOMe hydrochloride
CAS:25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.Fórmula:C18H23ClN2O5Forma y color:SolidPeso molecular:382.84Landipirdine
CAS:Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.Fórmula:C18H19FN2O3SPureza:97.50% - 99.33%Forma y color:SolidPeso molecular:362.42Venlafaxine hydrochloride
CAS:Venlafaxine HCl, a cyclohexanol phenethylamine, acts as an SNRI antidepressant.Fórmula:C17H28ClNO2Pureza:99.86%Forma y color:White Crystalline PowderPeso molecular:313.863Adatanserin hydrochloride
CAS:Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.Fórmula:C21H32ClN5OPureza:99.64%Forma y color:SolidPeso molecular:405.96Olopatadine hydrochloride
CAS:Olopatadine hydrochloride (ALO4943A) is an antihistamine with mast-cell stabilizing properties used as eye drops in the treatment of ALLERGIC CONJUNCTIVITIS.Fórmula:C21H23NO3·HClPureza:99.62% - 99.64%Forma y color:White SolidPeso molecular:373.87Latrepirdine dihydrochloride
CAS:Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Fórmula:C21H25N3·2HClPureza:98.45%Forma y color:SolidPeso molecular:392.37SR 57227 hydrochloride
CAS:SR 57227A (SR 57227 hydrochloride) is a potent, orally active and selective 5-HT3 receptor agonist. It with ability to cross the blood brain barrier.Fórmula:C10H14ClN3·HClPureza:99.89%Forma y color:SolidPeso molecular:248.15Ref: TM-T23394
5mg50,00€10mg74,00€25mg126,00€50mg210,00€100mg313,00€200mg445,00€1mL*10mM (DMSO)49,00€RS 56812 hydrochloride
CAS:5-HT3 partial agonistFórmula:C18H22ClN3O2Pureza:97.69%Forma y color:SolidPeso molecular:347.84N-Desmethyl Pimavanserin
CAS:N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.Fórmula:C24H32FN3O2Pureza:98.02%Forma y color:SolidPeso molecular:413.53Urapidil
CAS:Urapidil (Ebrantil), a sympatholytic antihypertensive drug, acts as a 5-HT1A receptor agonist and as an α1-adrenoceptor antagonist.Fórmula:C20H29N5O3Pureza:100% - 99.85%Forma y color:SolidPeso molecular:387.48Gepirone
CAS:Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.Fórmula:C19H29N5O2Pureza:99.35% - 99.77%Forma y color:SolidPeso molecular:359.47Pizotifen
CAS:Pizotifen is a serotonin antagonist with mild anticholinergic effects, used in migraine prevention. Not available in the USA.Fórmula:C19H21NSPureza:99.93%Forma y color:SolidPeso molecular:295.44Ondansetron
CAS:Ondansetron (GR 38032) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.Fórmula:C18H19N3OPureza:99.92%Forma y color:White To Yellow CrystalsPeso molecular:293.364-Hydroxy MPT
CAS:4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.Fórmula:C14H20N2OForma y color:SolidPeso molecular:232.32Olanzapine
CAS:Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.Fórmula:C17H20N4SPureza:100% - ≥95%Forma y color:Yellowish Crystalline PowderPeso molecular:312.43Desvenlafaxine succinate hydrate
CAS:Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).Fórmula:C20H33NO7Pureza:99.26%Forma y color:White Crystalline PowdePeso molecular:399.48Dolasetron Mesylate hydrate
CAS:Dolasetron Mesylate hydrate blocks 5HT3 to prevent chemo and radiotherapy nausea.Fórmula:C20H26N2O7SPureza:99.86% - 99.9%Forma y color:SolidPeso molecular:438.49cis-(Z)-Flupentixol dihydrochloride
CAS:cis-(Z)-Flupentixol dihydrochloride (Emergil) is a dopamine receptor antagonist.Fórmula:C23H27Cl2F3N2OSPureza:98.07%Forma y color:SolidPeso molecular:507.44Ebalzotan
CAS:NAE-086 is a high-affinity and selective 5-HT(1A) receptor ligand with a K(i) value of 4.5 nM in membranes from rat hippocampus.Fórmula:C19H30N2O2Pureza:99.08% - 99.41%Forma y color:SolidPeso molecular:318.45Relenopride
CAS:YKP 10811 (Relenopride) is a novel 5-HT4 receptor partial agonist, which can be used to study irritable bowel syndrome with constipation.Fórmula:C24H30ClFN4O4Pureza:98.91% - 99.20%Forma y color:SoildPeso molecular:492.97MM 77 dihydrochloride
CAS:MM 77 dihydrochloride is an effecitve 5-HT1A receptor postsynaptic antagonist with anxiolytic-like activity.Fórmula:C19H29Cl2N3O3Pureza:100.00%Forma y color:SolidPeso molecular:418.36Ref: TM-T23007
1mg86,00€5mg157,00€10mg215,00€25mg472,00€50mg687,00€100mg938,00€500mg1.882,00€1mL*10mM (DMSO)281,00€AL 34662
CAS:AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also aFórmula:C10H13N3OPureza:99.77%Forma y color:SolidPeso molecular:191.23Naluzotan hydrochloride
CAS:Naluzotan hydrochloride, a hERG K+ blocker (IC50: 3800 nM) and potent 5-HT1A agonist (IC50: ~20 nM, Ki: ~5.1 nM), is used in anxiety and depression studies.Fórmula:C23H39ClN4O3SPureza:98.61%Forma y color:SolidPeso molecular:487.1PNU 22394 hydrochloride
CAS:PNU 22394 hydrochloride is a 5-HT2C agonist and partial 5-HT2A/5-HT2B agonistFórmula:C13H17ClN2Pureza:97.83%Forma y color:SolidPeso molecular:236.74RS-67333
CAS:RS-67333 is a partial agonist of 5-HT4R with neuroprotective effects.Fórmula:C19H29ClN2O2Pureza:99.24%Forma y color:SolidPeso molecular:352.9
