
GluR
Inhibidores del Receptor de Glutamato son compuestos que bloquean la actividad de los receptores de glutamato, los principales receptores de neurotransmisores excitatorios en el cerebro. Estos receptores desempeñan un papel crucial en la transmisión sináptica, la plasticidad, el aprendizaje y la memoria. La desregulación de la señalización de glutamato está asociada con varios trastornos neurológicos, como la epilepsia, el accidente cerebrovascular y las enfermedades neurodegenerativas. Los inhibidores de los receptores de glutamato son esenciales para investigar los mecanismos de la excitotoxicidad y desarrollar estrategias neuroprotectoras. En CymitQuimica, ofrecemos una gama de inhibidores de receptores de glutamato para apoyar su investigación en la función sináptica, la neuroprotección y los trastornos cognitivos.
Productos de "GluR"
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Licostinel
CAS:Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia.Fórmula:C8H3Cl2N3O4Pureza:98.02%Forma y color:SolidPeso molecular:276.031-BCP
CAS:1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents.Fórmula:C13H15NO3Pureza:99.60%Forma y color:SolidPeso molecular:233.26Chelidamic acid
CAS:Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid is inhibitors of glutamate decarboxylase, with a Ki of 33 μM.Fórmula:C7H5NO5Pureza:98.11%Forma y color:Pale Yellow PowderPeso molecular:183.12DL-AP3
CAS:DL-AP3 is a competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.Fórmula:C3H8NO5PPureza:98.18% - ≥98%Forma y color:White PowderPeso molecular:169.07VU6012962
CAS:VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).Fórmula:C21H19F3N4O4Pureza:97% - 98.31%Forma y color:SolidPeso molecular:448.4Ref: TM-T13323
1mg37,00€2mg52,00€5mg79,00€10mg126,00€25mg236,00€50mg425,00€100mg625,00€1mL*10mM (DMSO)87,00€GYKI 52466 dihydrochloride
CAS:GYKI 52466 dihydrochloride is an AMPA/Kainate receptor antagonist with anticonvulsant activity and can be used to study neurological diseases.Fórmula:C17H17Cl2N3O2Pureza:99.38%Forma y color:SolidPeso molecular:366.24Pomaglumetad methionil anhydrous
CAS:LY2140023, potential schizophrenia treatment, is an oral prodrug of LY404039, a selective mGlu2/3 agonist.Fórmula:C12H18N2O7S2Pureza:98%Forma y color:SolidPeso molecular:366.41CX516
CAS:CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and MCI.Fórmula:C14H15N3OPureza:99.29% - ≥95%Forma y color:Tan SolidPeso molecular:241.29Transtorine
CAS:Transtorine (1,4-DIHYDRO-4-OXOQUINOLINE-2-CARBOXYLIC ACID) is a GluR and NMDA inhibitor.Fórmula:C10H7NO3Pureza:99.36%Forma y color:SolidPeso molecular:189.17HBT1
CAS:HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neuronsFórmula:C16H17F3N4O2SPureza:99.52%Forma y color:SolidPeso molecular:386.39MNI 137
CAS:MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.Fórmula:C15H9BrN4OPureza:97.21%Forma y color:SolidPeso molecular:341.16trans-ACPD
CAS:trans-ACPD ((±)-trans-ACPD) is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD.Fórmula:C7H11NO4Pureza:99.53%Forma y color:SolidPeso molecular:173.17Ref: TM-T3484
1mg48,00€2mg63,00€5mg89,00€10mg147,00€25mg279,00€50mg505,00€100mg730,00€1mL*10mM (DMSO)74,00€CFMTI
CAS:CFMTI: potent mGluR1 allosteric antagonist, 2000x selectivity over mGluR5, IC50: 2.6 nM.Fórmula:C19H16FN5OPureza:97.23%Forma y color:SolidPeso molecular:349.36Ref: TM-T3482
1mg60,00€2mg87,00€5mg127,00€10mg180,00€25mg321,00€50mg455,00€100mg635,00€1mL*10mM (DMSO)140,00€(R)-3,4-DCPG HCl
(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatalFórmula:C10H10ClNO6Pureza:98.36% - 99.89%Forma y color:SoildPeso molecular:275.64(R)-ADX-47273
CAS:(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).Fórmula:C20H17F2N3O2Pureza:99.87%Forma y color:SolidPeso molecular:369.36Ref: TM-T13441
2mg42,00€5mg65,00€10mg94,00€25mg170,00€50mg259,00€100mg391,00€200mg545,00€1mL*10mM (DMSO)71,00€AMPA receptor modulator-2
CAS:AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.Fórmula:C15H6F6N4OSPureza:99.62%Forma y color:SolidPeso molecular:404.29Ref: TM-T37734
1mg123,00€5mg298,00€10mg393,00€25mg628,00€50mg905,00€100mg1.254,00€1mL*10mM (DMSO)328,00€VU0155094
CAS:VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs.Fórmula:C24H24N2O4SPureza:98.00%Forma y color:SolidPeso molecular:436.52Ref: TM-T9011
1mg65,00€5mg116,00€10mg170,00€25mg284,00€50mg393,00€100mg567,00€200mg748,00€1mL*10mM (DMSO)134,00€MFZ 10-7
CAS:MFZ 10-7 is anegative allosteric modulator of the mGluR5.Fórmula:C15H9FN2Pureza:98.82%Forma y color:SolidPeso molecular:236.24Farampator
CAS:Farampator (CX-691) (CX-691;Org24448) is a positive modulator of AMPA receptor.Fórmula:C12H13N3O2Pureza:99.76% - 99.83%Forma y color:SolidPeso molecular:231.25Ref: TM-T3957
2mg34,00€5mg52,00€10mg74,00€25mg140,00€50mg235,00€100mg350,00€200mg497,00€1mL*10mM (DMSO)58,00€JNJ-42153605
CAS:JNJ-42153605 is a mGlu2 receptor positive allosteric modulator (EC50: 17 nM).Fórmula:C22H23F3N4Pureza:97.25% - 98.57%Forma y color:SolidPeso molecular:400.44Ref: TM-T3451
1mg34,00€2mg52,00€5mg81,00€10mg105,00€25mg180,00€50mg279,00€100mg396,00€200mg555,00€1mL*10mM (DMSO)84,00€