NMDAR
Los inhibidores del receptor de N-Metil-D-Aspartato (NMDAR) son compuestos que bloquean la actividad de los NMDARs, un subtipo de receptores de glutamato que desempeñan un papel crítico en la plasticidad sináptica, el aprendizaje y la memoria. La sobreactivación de los NMDARs está implicada en la excitotoxicidad, que puede llevar a daño neuronal y está asociada con condiciones como el accidente cerebrovascular, el trauma craneoencefálico y enfermedades neurodegenerativas. Los inhibidores de NMDAR son herramientas esenciales para estudiar la excitotoxicidad y para desarrollar terapias neuroprotectoras. En CymitQuimica, ofrecemos una gama de inhibidores de NMDAR para apoyar su investigación en función sináptica, neuroprotección y trastornos cognitivos.
Productos de "NMDAR"
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Dizocilpine Maleate
CAS:Dizocilpine Maleate (MK 801) is a potent noncompetitive antagonist of the NMDA receptor with Kd of 37.2 nM in rat brain membranes.Fórmula:C20H19NO4Pureza:99% - 99.96%Forma y color:White SolidPeso molecular:337.38SDZ 220-040
CAS:SDZ 220-040 是一种选择性哺乳动物 NMDA 受体拮抗剂,可诱导根系生长的部分无重力模式 。Fórmula:C16H16Cl2NO6PPureza:99.33%Forma y color:SolidPeso molecular:420.18L-689560
CAS:L-689560, a radiolabeled ligand, studies NMDA receptors, is an antagonist at GluN1 glycine site.Fórmula:C17H15Cl2N3O3Pureza:98%Forma y color:SolidPeso molecular:380.23CIQ
CAS:CIQ is a subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit. EC50 value: 2.7 μM for NR2C and 2.8 μM for NR2D.Fórmula:C26H26ClNO5Pureza:99.50%Forma y color:SolidPeso molecular:467.94Dalzanemdor
CAS:Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitiveFórmula:C27H43F3O2Pureza:100% - 98.20%Forma y color:SolidPeso molecular:456.621-Aminocyclobutanecarboxylic acid
CAS:1-Aminocyclobutanecarboxylic acid (ACBC) is a NMDA receptor partial agonist. 1-Aminocyclobutanecarboxylic acid act at the glycine site, NR1[1].Fórmula:C5H9NO2Pureza:99.94%Forma y color:White To Tan Powder Crystals Crystalline Powder And/Or With ChunksPeso molecular:115.13Aptiganel hydrochloride
CAS:Aptiganel hydrochloride(Cerestat) is the salt form of Aptiganel.Aptiganel is a non-competitive NMDA antagonist with neuroprotective effects used in the treatment of stroke and focal cerebral ischemia.Fórmula:C20H22ClN3Pureza:99.89%Forma y color:SolidPeso molecular:339.86Ref: TM-T38068
1mg38,00€5mg80,00€10mg126,00€25mg267,00€50mg462,00€100mg700,00€200mg995,00€1mL*10mM (DMSO)88,00€Cycloleucine
CAS:Cycloleucine is an antagonist of NMDA receptor associated glycine receptor with a Ki of 600 μM.Fórmula:C6H11NO2Pureza:98.13%Forma y color:SolidPeso molecular:129.16Flupirtine maleate
CAS:Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.Fórmula:C15H17FN4O2·C4H4O4Pureza:99.50% - 99.9%Forma y color:Off-White Crystalline PowderPeso molecular:420.39Flutriafol
CAS:Flutriafol is a pesticide, demethylation inhibitor, and NMDA receptor agonistFórmula:C16H13F2N3OPureza:98.75%Forma y color:SolidPeso molecular:301.29DNQX disodium salt
CAS:DNQX disodium salt is a water-soluble form of selective antagonist of non-NMDA receptorFórmula:C8H2N4Na2O6Pureza:98.93%Forma y color:SolidPeso molecular:296.1Ref: TM-T8459
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)170,00€CGP 78608 hydrochloride
CAS:CGP 78608 hydrochloride: NMDA receptor antagonist (IC50=6 nM), anticonvulsant, enhances GluN1/GluN3A currents (EC50=26.3 nM).Fórmula:C11H14BrClN3O5PPureza:98.96% - 99.68%Forma y color:SolidPeso molecular:414.58Procyclidine hydrochloride
CAS:Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.Fórmula:C19H30ClNOPureza:99.95%Forma y color:Crystals From Petroleum Ether White PowderPeso molecular:323.9L-701324
CAS:L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant.Fórmula:C21H14ClNO3Pureza:100% - 98.63%Forma y color:SolidPeso molecular:363.79Ro 25-6981 Maleate
CAS:Ro 25-6981 Maleate is an NMDA receptor antagonist used in the study of neurological disorders such as Parkinson's and epilepsy.Fórmula:C26H33NO6Pureza:99.42%Forma y color:SolidPeso molecular:455.54Lanicemine dihydrochloride
CAS:Lanicemine dihydrochloride (AZD-6765 dihydrochloride) is an NMDA channel blocker with antidepressant activity and can be used to study neurological diseases.Fórmula:C13H16Cl2N2Pureza:99.43%Forma y color:SolidPeso molecular:271.19Ref: TM-T60471
2mg35,00€5mg52,00€10mg93,00€25mg170,00€50mg283,00€100mg432,00€500mg938,00€1mL*10mM (DMSO)47,00€TCS 46b
CAS:TCS 46b is a NR1A/NR2B NMDA receptor antagonist with oral activity.Fórmula:C22H23N3OPureza:99% - 99.81%Forma y color:SolidPeso molecular:345.44GNE-8324
CAS:GNE-8324 is a GluN2A selective positive allosteric modulator that enhances NMDAR-mediated synaptic responses in inhibitory, but not excitatory, neurons.Fórmula:C18H18FN3OSPureza:98.68% - 99.34%Forma y color:SolidPeso molecular:343.42Ref: TM-T31981
1mg150,00€5mg359,00€10mg532,00€25mg848,00€50mg1.121,00€100mg1.539,00€200mg2.072,00€1mL*10mM (DMSO)368,00€Rapastinel Trifluoroacetate
CAS:Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) is an NMDA receptor modulator with glycine-site partial agonist properties.Fórmula:C20H32F3N5O8Pureza:99.01% - 99.77%Forma y color:SolidPeso molecular:527.49Ref: TM-T5819
1mg39,00€5mg101,00€10mg170,00€25mg305,00€50mg419,00€100mg562,00€200mg743,00€1mL*10mM (DMSO)116,00€Traxoprodil
CAS:Traxoprodil (CP101606) is a selective NMDA antagonist and protects hippocampal neurons (IC50: 10 nM).Fórmula:C20H25NO3Pureza:99.89%Forma y color:SolidPeso molecular:327.42
