Src
Los inhibidores de Src son compuestos que se dirigen a las quinasas de la familia Src, que están involucradas en diversos procesos celulares, como el crecimiento, la diferenciación y la angiogénesis. Las quinasas Src desempeñan un papel crucial en las vías de señalización que promueven la formación de nuevos vasos sanguíneos en los tumores. Inhibir Src puede interrumpir estas vías, reduciendo así la angiogénesis y el crecimiento tumoral. Los inhibidores de Src se utilizan ampliamente en la investigación del cáncer y en el desarrollo terapéutico. En CymitQuimica, ofrecemos una selección completa de inhibidores de Src de alta calidad para apoyar su investigación en oncología, señalización celular y angiogénesis.
Productos de "Src"
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PP 1
CAS:Fórmula:C16H19N5Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:281.36Dasatinib
CAS:Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Fórmula:C22H26ClN7O2SPureza:99.59% - 99.86%Forma y color:Pale-Yellow SolidPeso molecular:488.01TL02-59
CAS:TL02-59: Fgr inhibitor (IC50=0.03nM), also targets Lyn (0.1nM), Hck (160nM), halts acute myelogenous leukemia growth.Fórmula:C32H34F3N5O4Pureza:95.63%Forma y color:SolidPeso molecular:609.64Ref: TM-T13186
1mg71,00€5mg135,00€10mg212,00€25mg359,00€50mg512,00€100mg695,00€200mg937,00€1mL*10mM (DMSO)170,00€Bosutinib
CAS:Fórmula:C26H29Cl2N5O3Pureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:530.45Dasatinib
CAS:Fórmula:C22H26ClN7O2SPureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:488.01PD173955
CAS:PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR andFórmula:C21H16Cl2N4OSPureza:98.52% - 99.28%Forma y color:SolidPeso molecular:443.35RK-24466
CAS:RK-24466 (KIN 001-51) is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.Fórmula:C23H22N4OPureza:98.07%Forma y color:SolidPeso molecular:370.45Ref: TM-T16760
1mg66,00€5mg144,00€10mg227,00€25mg393,00€50mg588,00€100mg905,00€1mL*10mM (DMSO)159,00€Tirbanibulin Mesylate
CAS:Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Fórmula:C27H33N3O6SPureza:99.42%Forma y color:SolidPeso molecular:527.63Ref: TM-T15675
2mg38,00€5mg56,00€10mg70,00€25mg126,00€50mg243,00€100mg416,00€200mg562,00€1mL*10mM (DMSO)65,00€Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Fórmula:C28H30N6OSPureza:100% - 99.55%Forma y color:SolidPeso molecular:498.64Ponatinib
CAS:Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFórmula:C29H27F3N6OPureza:98% - 99.60%Forma y color:SolidPeso molecular:532.56Tirbanibulin
CAS:Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Fórmula:C26H29N3O3Pureza:99.43% - 99.67%Forma y color:SolidPeso molecular:431.53Ref: TM-T6345
1mg35,00€5mg66,00€10mg81,00€25mg159,00€50mg280,00€100mg470,00€500mg1.035,00€1mL*10mM (DMSO)70,00€Pelitinib
CAS:Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).Fórmula:C24H23ClFN5O2Pureza:98.37% - 99.86%Forma y color:Off-White SolidPeso molecular:467.92Hck-IN-1
CAS:Hck-IN-1 selectively inhibits Nef:Hck, IC50: 2.8 μM; >20 μM for Hck alone. Potent HIV-1 Nef antagonist, IC50: 100-300 nM for HIV-1 replication.Fórmula:C16H11ClN6O3SPureza:99.07%Forma y color:SolidPeso molecular:402.81Ref: TM-T11538
1mg97,00€5mg216,00€10mg344,00€25mg567,00€50mg825,00€100mg1.121,00€200mg1.510,00€1mL*10mM (DMSO)240,00€squarunkinA
CAS:squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-Fórmula:C25H32F3N5O4Pureza:99.29%Forma y color:SolidPeso molecular:523.55Anti-Src Antibody (1E789)
Anti-Src Antibody (1E789) is an antibody targeting Src. Anti-Src Antibody (1E789) can be used in ELISA, WB, IF, FCM.Forma y color:Odour LiquidAP23846
CAS:AP23846 is an Src family kinase inhibitor that reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines.Fórmula:C24H34N5OPPureza:100%Forma y color:SolidPeso molecular:439.53eCF506
CAS:eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)Fórmula:C26H38N8O3Pureza:97.85% - 98.16%Forma y color:SolidPeso molecular:510.63β-Hydroxyisovalerylshikonin
CAS:Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumorFórmula:C21H24O7Pureza:98.16%Forma y color:SolidPeso molecular:388.41CGP062464
CAS:CGP062464 is an inhibitor of the tyrosine kinase c-Src, with an IC50 of less than 50 nM. It is utilized in research related to osteoporosis and tumor-induced hypercalcemia.Fórmula:C18H14N4Forma y color:SolidPeso molecular:286.331Spebrutinib
CAS:Spebrutinib (LMK-435) is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplasticFórmula:C22H22FN5O3Pureza:100% - 97.02%Forma y color:SolidPeso molecular:423.44
