Src
Los inhibidores de Src son compuestos que se dirigen a las quinasas de la familia Src, que están involucradas en diversos procesos celulares, como el crecimiento, la diferenciación y la angiogénesis. Las quinasas Src desempeñan un papel crucial en las vías de señalización que promueven la formación de nuevos vasos sanguíneos en los tumores. Inhibir Src puede interrumpir estas vías, reduciendo así la angiogénesis y el crecimiento tumoral. Los inhibidores de Src se utilizan ampliamente en la investigación del cáncer y en el desarrollo terapéutico. En CymitQuimica, ofrecemos una selección completa de inhibidores de Src de alta calidad para apoyar su investigación en oncología, señalización celular y angiogénesis.
Productos de "Src"
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Hck-IN-2
Hck-IN-2 (Compound 8e) acts as an HCK inhibitor with demonstrated cytotoxic effects on tumor cells. It exhibits an IC50 of 19.58 μM for MDA-MB231 cells and 1.42 μM for MCF-7 cells. Additionally, Hck-IN-2 possesses antitumor activity.Fórmula:C36H35FN6O10Forma y color:SolidPeso molecular:730.696KB SRC 4
CAS:KB SRC 4 is a selective and potent c-Src inhibitor with antitumour activity that inhibits the growth of cancer cells.CAS 번호13460-73-83-4Fórmula:C32H23ClN8Pureza:99.66% - 99.66%Forma y color:SolidPeso molecular:555.03TG 100572 Hydrochloride
CAS:TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.Fórmula:C26H27Cl2N5O2Pureza:98%Forma y color:SolidPeso molecular:512.43Saracatinib
CAS:Fórmula:C27H32ClN5O5Pureza:>95.0%(HPLC)(qNMR)Forma y color:White to Light yellow powder to crystalPeso molecular:542.03Periplocin
CAS:Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.Fórmula:C36H56O13Pureza:99.37% - 99.66%Forma y color:SolidPeso molecular:696.82Ref: TM-T5S1982
1mg35,00€5mg77,00€10mg106,00€25mg170,00€50mg253,00€100mg375,00€500mg892,00€1mL*10mM (DMSO)107,00€MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Fórmula:C9H7NO4Pureza:98.53%Forma y color:Yellow PowderPeso molecular:193.16XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Fórmula:C22H31N9OPureza:99.07%Forma y color:SolidPeso molecular:437.54Ref: TM-T17267
1mg56,00€2mg78,00€5mg99,00€10mg149,00€25mg258,00€50mg393,00€100mg582,00€1mL*10mM (DMSO)110,00€Saracatinib
CAS:Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.Fórmula:C27H32ClN5O5Pureza:98% - 99.63%Forma y color:SolidPeso molecular:542.03Pyridostatin TFA
CAS:Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-Fórmula:C37H35F9N8O11Pureza:97.09% - 99.84%Forma y color:SolidPeso molecular:938.71ENMD-2076
CAS:ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Fórmula:C21H25N7Pureza:97.63% - ≥95%Forma y color:SolidPeso molecular:375.47Ref: TM-T2358
1mg51,00€2mg72,00€5mg105,00€10mg159,00€25mg279,00€50mg462,00€100mg648,00€1mL*10mM (DMSO)116,00€PD-089828
CAS:PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).Fórmula:C18H18Cl2N6OPureza:96.78%Forma y color:SolidPeso molecular:405.28Src Inhibitor 3
CAS:Src Inhibitor 3 blocks c-Src kinase (IC50 <3 nM CSK HTRF, <4 nM Caliper), boosting T cell growth from receptor signals.Fórmula:C34H32ClFN8O4Pureza:98.74%Forma y color:SolidPeso molecular:671.12Ref: TM-T13000
1mg92,00€5mg187,00€10mg320,00€25mg507,00€50mg702,00€100mgA consultar1mL*10mM (DMSO)279,00€PP121
CAS:PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Fórmula:C17H17N7Pureza:99.19% - 99.67%Forma y color:SolidPeso molecular:319.36Tirbanibulin dihydrochloride
CAS:Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Fórmula:C26H31Cl2N3O3Pureza:98%Forma y color:SolidPeso molecular:504.45Masitinib mesylate
CAS:Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;Fórmula:C29H34N6O4S2Pureza:100% - 97.67%Forma y color:SolidPeso molecular:594.75Ref: TM-T8544
5mg35,00€10mg51,00€25mg77,00€50mg95,00€100mg144,00€200mg225,00€500mg373,00€1mL*10mM (DMSO)49,00€PI3K-IN-1
CAS:PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.Fórmula:C31H29N5O6SPureza:97.03% - 98%Forma y color:SolidPeso molecular:599.667-Hydroxy-4H-chromen-4-one
CAS:7-Hydroxy-4H-chromen-4-one (7-hydroxy-4-benzopyrone) is a Src kinase inhibitor (IC50 of <300 μM).Fórmula:C9H6O3Pureza:97.65%Forma y color:SolidPeso molecular:162.14AD80
CAS:AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.Fórmula:C22H19F4N7OPureza:100% - 99.49%Forma y color:SolidPeso molecular:473.43Ref: TM-T4301
1mg47,00€5mg92,00€10mg145,00€25mg283,00€50mg464,00€100mg680,00€500mg1.406,00€1mL*10mM (DMSO)96,00€PP1
CAS:PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.Fórmula:C16H19N5Pureza:99% - 99.97%Forma y color:Off-White To Grey SolidPeso molecular:281.36Ref: TM-T6196
1mg40,00€2mg52,00€5mg88,00€10mg118,00€25mg202,00€50mg283,00€100mg444,00€500mg998,00€1mL*10mM (DMSO)94,00€1-Naphthyl PP1
CAS:Fórmula:C19H19N5Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:317.40
