Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Productos de "Señalización citoesquelética"
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PKCθ pseudosubstrate peptide inhibitor,myristoylated
Myristoylated PKCθ pseudosubstrate peptide inhibitor is a synthetic peptide utilized to investigate the mechanism of action of protein kinase C theta (PKCθ) [1Fórmula:C105H184N36O21SPureza:98%Forma y color:SolidPeso molecular:2318.88Miransertib
CAS:Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor.Fórmula:C27H24N6Pureza:98.83% - ≥95%Forma y color:SolidPeso molecular:432.52Ref: TM-T3467
1mg52,00€5mg97,00€10mg169,00€25mg344,00€50mg567,00€100mg908,00€500mg1.795,00€1mL*10mM (DMSO)114,00€Defactinib hydrochloride
CAS:Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK.Fórmula:C20H22ClF3N8O3SPureza:98.06% - 98.78%Forma y color:SolidPeso molecular:546.95Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Fórmula:C35H30N4O4Pureza:100% - 99.47%Forma y color:SolidPeso molecular:570.64Ref: TM-T3211
1mg51,00€5mg88,00€10mg126,00€25mg216,00€50mg328,00€100mg487,00€500mg1.093,00€1mL*10mM (DMSO)96,00€LY3372689
CAS:LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer's disease.Fórmula:C16H22FN5O3SPureza:99.27% - 99.45%Forma y color:SolidPeso molecular:383.44Ref: TM-T61661
1mg99,00€5mg235,00€10mg354,00€25mg635,00€50mg935,00€100mg1.415,00€1mL*10mM (DMSO)259,00€Multi-kinase inhibitor 1
CAS:Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Fórmula:C20H17F3N4O3Pureza:99.34%Forma y color:SolidPeso molecular:418.37FRAX597
CAS:FRAX597 is an effective, ATP-competitive inhibitor of group I PAKs, and for PAK1(IC50=8 nM), PAK2(IC50=13 nM), and PAK3 (IC50=19 nM).Fórmula:C29H28ClN7OSPureza:97.34% - 99.85%Forma y color:SolidPeso molecular:558.1Ansamitocin P 3'
CAS:Ansamitocin P 3' (Maytansinol butyrate) is an antibody-drug conjugate cytotoxin with antitumor activity.Fórmula:C32H43ClN2O9Pureza:98.16% - 99.16%Forma y color:SolidPeso molecular:635.14Ref: TM-T1910
2mg34,00€5mg50,00€10mg84,00€25mg145,00€50mg229,00€100mg340,00€200mg472,00€1mL*10mM (DMSO)70,00€Ifebemtinib
CAS:Ifebemtinib (BI-853520) is an adhesion plaque kinase inhibitor with anti-tumour activity for the study of breast cancer.Fórmula:C28H28F4N6O4Pureza:98.07% - 99.82%Forma y color:SolidPeso molecular:588.55Ionomycin calcium
CAS:Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.Fórmula:C41H70CaO9Pureza:98% - 98.11%Forma y color:SolidPeso molecular:747.07NAMI-A
CAS:NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.Fórmula:C8H15Cl4N4ORuSPureza:98%Forma y color:SolidPeso molecular:458.18Ipfencarbazone
CAS:Ipfencarbazone herbicide agent, is a substance being developed for the control of weeds such as watergrass in rice.Fórmula:C18H14Cl2F2N4O2Forma y color:SolidPeso molecular:427.23Dynapyrazole A
CAS:Dynapyrazole A inhibits dynein 1 and 2 (IC50s: 2.3, 2.6 μM) and Hedgehog signaling (IC50: 1.9 μM).Fórmula:C20H12ClIN4OPureza:98.01%Forma y color:SolidPeso molecular:486.69RWJ 50271
CAS:RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.Fórmula:C18H17F3N4O2SPureza:99.09%Forma y color:SolidPeso molecular:410.41Ref: TM-T12783
1mg127,00€5mg311,00€10mg472,00€25mg747,00€50mg1.017,00€100mg1.311,00€200mg1.786,00€1mL*10mM (DMSO)344,00€AMP-945
CAS:AMP-945 is a proprietary focal adhesion kinase (FAK) inhibitor.Fórmula:C28H32F3N5O2Pureza:99.60%Forma y color:SolidPeso molecular:527.58Ref: TM-T9576
1mg97,00€5mg188,00€10mg311,00€25mg533,00€50mg755,00€100mg1.035,00€1mL*10mM (DMSO)254,00€Etrolizumab
CAS:MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.Pureza:95% - 95%Forma y color:LiquidAdhesamine diTFA
CAS:Adhesamine diTFA, a dumbbell-shaped molecule, activates the MAPK/FAK pathway. It promotes adhesion and growth in mammalian cells and accelerates differentiation and enhances the survival rate of primary cultured mouse hippocampal neurons.Fórmula:C28H32Cl2F6N8O6S2Forma y color:SolidPeso molecular:825.63BX-2819
CAS:BX-2819 is an Hsp90 inhibitor that exhibits potent antiproliferative activity with an IC50 of 41 nM .Fórmula:C21H24N4O4SPureza:98%Forma y color:SolidPeso molecular:428.51αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).Fórmula:C28H35F3N6O8SPureza:98%Forma y color:SolidPeso molecular:672.67Hydroxy-Dynasore
CAS:Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM,Fórmula:C18H14N2O5Pureza:100% - 97.60%Forma y color:SolidPeso molecular:338.31Ref: TM-T6822
5mg50,00€10mg84,00€25mg137,00€50mg221,00€100mg329,00€200mg490,00€500mg783,00€1mL*10mM (DMSO)55,00€αvβ6-IN-1
αvβ6-IN-1 (compound 28) is an effective orally active inhibitor of αvβ6 integrin (αvβ6integrin), with a pIC50 value of 8.1. This compound shows potential for research in idiopathic pulmonary fibrosis.Fórmula:C25H32F2N4O3Forma y color:SolidPeso molecular:474.5416-38-Thymosin β4 (cattle) (TFA)
Thymosin β4 (cattle) TFA is a high-affinity activator of MLCK that operates independently of Ca2+ [1].Fórmula:C120H205F3N32O43Pureza:98%Forma y color:SolidPeso molecular:2841.1K858 (Racemic)
CAS:K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.Fórmula:C13H15N3O2SPureza:100%Forma y color:SolidPeso molecular:277.34AZ13705339
CAS:AZ13705339 is an effective inhibitor of PAK1 with an IC50 of 0.33 nM and a Kd of 0.28 nM.Fórmula:C33H36FN7O3SPureza:98.57%Forma y color:SolidPeso molecular:629.75FAK-IN-7
CAS:FAK-IN-7 has potential antiproliferative activity and is a FAK inhibitor.Fórmula:C16H13N3OSPureza:98.2%Forma y color:SolidPeso molecular:295.36AJH-836
CAS:AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation ofFórmula:C22H38O5Pureza:98%Forma y color:SolidPeso molecular:382.5310-Deacetyltaxol
CAS:10-Deacetyltaxol (10-DAT) is extracted from Taxus brevifolia barks.Fórmula:C45H49NO13Pureza:94.63% - 99.93%Forma y color:SolidPeso molecular:811.87Tadocizumab
CAS:Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.Forma y color:LiquidKNK437
CAS:KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40).Fórmula:C13H11NO4Pureza:98.90%Forma y color:SolidPeso molecular:245.23PKC-IN-1
CAS:PKC-IN-1 is an ATP-competitive and reversible conventional PKC enzymes inhibitor (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with IC50s of 2.3, 8.1, 7.6,Fórmula:C25H37FN8O2Pureza:98% - 98.79%Forma y color:SolidPeso molecular:500.61Gamitrinib TPP
CAS:Gamitrinib TPP targets mitochondrial HSP90, inhibiting cancer, and blocks mitochondrial matrix.Fórmula:C52H65N3O8PPureza:98%Forma y color:SolidPeso molecular:891.078API-1
CAS:API-1 (NSC-177223) is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .Fórmula:C13H15N5O6Pureza:99.07%Forma y color:SolidPeso molecular:337.29Ref: TM-T8969
1mg59,00€5mg125,00€10mg207,00€25mg376,00€50mg562,00€100mg787,00€200mg1.035,00€1mL*10mM (DMSO)133,00€AKT-IN-1
CAS:AKT-IN-1 (AZD-26) is an allosteric AKT inhibitor (IC50: 1.04 μM).Fórmula:C22H21N3OPureza:98.63%Forma y color:SolidPeso molecular:343.42Ref: TM-T4489
1mg113,00€2mg158,00€5mg235,00€10mg400,00€25mg652,00€50mg909,00€100mg1.225,00€1mL*10mM (DMSO)188,00€HSP70/SIRT2-IN-2
CAS:HSP70/SIRT2-IN-2 (Compounds 1a), a dual inhibitor of SIRT2 and HSP70, exhibits an IC50 of 45.1±5.0 μM against SIRT2 and demonstrates antitumor activity [1].Fórmula:C17H13N3S3Pureza:98%Forma y color:SolidPeso molecular:355.5LXH254
CAS:LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.Fórmula:C25H25F3N4O4Pureza:98.3% - 99.92%Forma y color:SolidPeso molecular:502.49Ref: TM-T11898
1mg52,00€5mg122,00€10mg185,00€25mg363,00€50mg567,00€100mg690,00€200mg948,00€500mg1.444,00€1mL*10mM (DMSO)135,00€Debio 0932
CAS:Debio 0932 (CUDC-305) is a Hsp9 inhibitor, apoptosis, and has the advantage of being orally available and cross the BBB for cancers NSCLC and neuroblastoma.Fórmula:C22H30N6O2SPureza:98.98%Forma y color:SolidPeso molecular:442.58AT9283
CAS:AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).Fórmula:C19H23N7O2Pureza:99.83% - 99.98%Forma y color:SolidPeso molecular:381.43Ref: TM-T3068
1mg47,00€2mg60,00€5mg95,00€10mg170,00€25mg299,00€50mg499,00€100mg723,00€1mL*10mM (DMSO)97,00€Bisindolylmaleimide III
CAS:Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6Fórmula:C23H20N4O2Pureza:98.6%Forma y color:SolidPeso molecular:384.43Pifithrin-μ
CAS:Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.Fórmula:C8H7NO2SPureza:99.33% - 99.79%Forma y color:SolidPeso molecular:181.21KP-23172
CAS:KP-23172 is a inhibitor of PI3-K/Akt pathway.Fórmula:C10H4N6OPureza:98%Forma y color:SolidPeso molecular:224.18ML346
CAS:ML346 is a novel activator of Hsp70.Fórmula:C14H12N2O4Pureza:99.25% - 99.29%Forma y color:SolidPeso molecular:272.26Ref: TM-T3594
1mg40,00€2mg52,00€5mg85,00€10mg115,00€25mg172,00€50mg274,00€100mg427,00€500mg938,00€1mL*10mM (DMSO)85,00€Degrasyn
CAS:Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.Fórmula:C19H18BrN3OPureza:98.32% - 99.98%Forma y color:SolidPeso molecular:384.27Ref: TM-T6300
2mg44,00€5mg64,00€10mg97,00€25mg198,00€50mg340,00€100mg532,00€200mg747,00€1mL*10mM (DMSO)69,00€Phorbol 12,13-dibutyrate
CAS:Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.Fórmula:C28H40O8Pureza:100% - 99.32%Forma y color:SolidPeso molecular:504.61Ref: TM-T16526
1mg62,00€5mg169,00€10mg283,00€25mg557,00€50mg795,00€100mg1.074,00€1mL*10mM (DMSO)180,00€Akt3 degrader 1
CAS:Akt3 degrader 1 counters Osimertinib resistance in NSCLC, inhibits cell growth, and reduces mouse tumors.Fórmula:C53H72N8O4Pureza:98.18% - 99.14%Forma y color:SolidPeso molecular:885.19VTX-27
CAS:VTX-27 is a selective inhibitor of protein kinase C θ (PKC θ) (Kis: 0.08 nM and 16 nM for PKC θ and PKC δ).Fórmula:C20H24ClFN6OPureza:99.49%Forma y color:SolidPeso molecular:418.9Ref: TM-T13314
1mg93,00€2mg125,00€5mg244,00€10mg364,00€25mg562,00€50mg780,00€100mg1.035,00€1mL*10mM (DMSO)225,00€Ruboxistaurin hydrochloride
CAS:Ruboxistaurin HCl (LY 333531) selectively inhibits PKCβI/II with IC50 of 4.7/5.9 nM; much less effective on other PKC types and ATP-kinases.Fórmula:C28H28N4O3·HClPureza:98.44% - 99.22%Forma y color:SolidPeso molecular:505.01Ref: TM-T3689
1mg71,00€2mg93,00€5mg157,00€10mg256,00€25mg513,00€50mg740,00€100mg1.035,00€500mg2.072,00€1mL*10mM (DMSO)202,00€Imatinib
CAS:Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFórmula:C29H31N7OPureza:100% - 99.94%Forma y color:Off White PowderPeso molecular:493.6Tetradecyltrimethylammonium bromide
CAS:Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.Fórmula:C17H38BrNPureza:100%Forma y color:SolidPeso molecular:336.39K-252b
CAS:K-252b, an indolocarbazole derived from the actinomycete Nocardiopsis, functions as a protein kinase C (PKC) inhibitor.Fórmula:C26H19N3O5Pureza:98%Forma y color:Ready-To-Use SolutionPeso molecular:453.45Larazotide acetate
CAS:Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.Fórmula:C34H59N9O12Pureza:95.53%Forma y color:SolidPeso molecular:785.89para-Nitroblebbistatin
CAS:para-Nitroblebbistatin is a non-cytotoxic, non-fluorescent, photostable, and specific inhibitor of myosin II.Cost-effective and quality-assured.Fórmula:C18H15N3O4Pureza:100% - 99.92%Forma y color:SolidPeso molecular:337.33Ref: TM-T12360
1mg87,00€5mg212,00€10mg316,00€25mg512,00€50mg695,00€100mg940,00€200mg1.264,00€1mL*10mM (DMSO)215,00€Chromeceptin
CAS:Chromeceptin is an inhibitor of the IGF signaling pathway, decreases the numbers of tumorsphere, and inhibits the AKT/mTOR pathway.Fórmula:C19H16F3N3OPureza:99.72%Forma y color:SoildPeso molecular:359.35Ref: TM-T60055
5mg50,00€10mg74,00€25mg140,00€50mg197,00€100mg306,00€200mg442,00€1mL*10mM (DMSO)51,00€PU-H71
CAS:PU-H71 is an effective selective HSP90 inhibitor with an IC50 of 51 nM.Fórmula:C18H21IN6O2SPureza:98.31%Forma y color:SolidPeso molecular:512.37Delcasertib
CAS:Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).Fórmula:C120H199N45O34S2Pureza:99.96%Forma y color:SolidPeso molecular:2880.28Ref: TM-T11740
1mg202,00€5mg512,00€10mg740,00€25mg1.121,00€50mg1.539,00€100mg2.072,00€1mL*10mM (DMSO)1.691,00€1-Oleoyl-2-acetyl-sn-glycerol
CAS:1-Oleoyl-2-acetyl-sn-glycerol (1-oleoyl-2-acetyl-glycerol) is a PKC activator that induces superoxide production.Fórmula:C23H42O5Forma y color:SolidPeso molecular:398.58Nilotinib hydrochloride
CAS:Nilotinib HCl (AMN-107 HCl), an oral Bcr-Abl inhibitor, targets neuroinflammation, cognitive issues, and chronic myelogenous leukemia.Fórmula:C28H23ClF3N7OPureza:100%Forma y color:SolidPeso molecular:565.98Hispidin
CAS:Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective propertiesFórmula:C13H10O5Pureza:98.27%Forma y color:White Crystalline PowderPeso molecular:246.22Ref: TM-T7792
1mg88,00€5mg187,00€10mg298,00€25mg533,00€50mg747,00€100mg1.017,00€1mL*10mM (DMSO)207,00€SB-743921 hydrochloride
CAS:SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).Fórmula:C31H34Cl2N2O3Pureza:95.58% - 99.70%Forma y color:SolidPeso molecular:553.52Ref: TM-T2255
1mg42,00€5mg106,00€10mg163,00€25mg278,00€50mg429,00€100mg657,00€500mg1.501,00€1mL*10mM (DMSO)130,00€PPY A
CAS:PPY A is a potent inhibitor of T315l mutant and wild-type Abl kinase and inhibits the growth of Bcr-Abl T315l mutant or wild-type Bcr-Abl gene-transformed cellsFórmula:C22H20N4O2Pureza:98.77%Forma y color:SolidPeso molecular:372.42ILK-IN-2
CAS:ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.Fórmula:C30H30F3N5OPureza:99.30%Forma y color:SolidPeso molecular:533.59Ref: TM-T5488
1mg48,00€5mg97,00€10mg128,00€25mg162,00€50mg192,00€100mg281,00€200mg408,00€1mL*10mM (DMSO)137,00€Rosabulin
CAS:v Rosabulin (STA 5312) is an orally active microtubule inhibitor with potency.Fórmula:C22H16N4O2SPureza:98.06%Forma y color:SolidPeso molecular:400.45Ref: TM-T16788
1mg97,00€5mg243,00€10mg364,00€25mg658,00€50mg938,00€100mg1.415,00€1mL*10mM (DMSO)265,00€Arg-Gly-Asp-Ser acetate
Arg-Gly-Asp-Ser acetate targets integrin, binding pro-caspase-8, -9, -3, but not -1; inhibits receptor function.Fórmula:C17H31N7O10Pureza:98.14%Forma y color:SolidPeso molecular:493.47Hsp90-IN-34
CAS:Hsp90-IN-34 (compound HAM-1) is a chemical inhibitor that targets the Aha1-Hsp90 chaperone complex with high affinity (KDapp=23.5 µM). It modulates the ATPase activity of Hsp90 by affecting the interaction between Hsp90 and Aha1.Fórmula:C22H14F2N6OForma y color:SolidPeso molecular:416.38Mivobulin
CAS:Mivobulin is an inhibitor of tubulin .Fórmula:C17H19N5O2Pureza:98%Forma y color:SolidPeso molecular:325.37FPA-124
CAS:FPA-124 is a cell-permeable copper complex that acts as a selective Akt (protein kinase B) inhibitor to induce apoptosis in a variety of cancer cell lines.Fórmula:C11H9Cl2CuN3O2SPureza:95.04%Forma y color:SolidPeso molecular:381.73ZLY06
CAS:ZLY06 is a dual agonist of peroxisome proliferator-activated receptors (PPAR) δ and γ with oral activity (PPAR δ: EC50=341 nM; PPARγ: EC50=237 nM). It mediates the upregulation of CD36 and induces hepatic lipid accumulation by inhibiting the phosphorylation of AKT1. Moreover, ZLY06 significantly improves glucose and lipid metabolism without increasing body weight, primarily by enhancing the β-oxidation of fatty acids and reducing hepatic lipid synthesis, thereby alleviating fatty liver disease.Fórmula:C25H26O6Forma y color:SolidPeso molecular:422.47ATN-161 trifluoroacetate salt
CAS:ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Fórmula:C25H36F3N9O10SPureza:98% - 99.98%Forma y color:SolidPeso molecular:711.67PND-1186
CAS:PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Fórmula:C25H26F3N5O3Pureza:99.14% - 99.75%Forma y color:SolidPeso molecular:501.5Catumaxomab
CAS:Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.Pureza:95%Forma y color:LiquidCK-869
CAS:CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor(IC50 of 7 μM),and is useful tools for the investigation of the Arp2/3 complex.Fórmula:C17H16BrNO3SPureza:99.85%Forma y color:SolidPeso molecular:394.28Zelavespib hydrochloride
Zelavespib (PU-H71) hydrochloride is a potent inhibitor of Hsp90, exhibiting an IC50 value of 51 nM in MDA-MB-468 cells.Pureza:98%Forma y color:Odour SolidSC79
CAS:SC79 is an AKT agonist with specificity and blood-brain barrier permeability.Fórmula:C17H17ClN2O5Pureza:98% - 99.93%Forma y color:SolidPeso molecular:364.78β-glycosidase-IN-1
CAS:β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.Fórmula:C13H23NO5Pureza:98%Forma y color:SolidPeso molecular:273.33A-3 hydrochloride
CAS:A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.Fórmula:C12H14Cl2N2O2SPureza:99.32%Forma y color:SolidPeso molecular:321.22Ref: TM-T14069
1mg35,00€5mg66,00€10mg96,00€25mg170,00€50mg274,00€100mg439,00€500mg938,00€1mL*10mM (DMSO)90,00€(8R)-8-Hydroxyepoxyboetirane A
(8R)-8-Hydroxyepoxyboetirane A is a neuroactivating compound that interacts with PKCδ-C1B. This compound binds into the PKC enzyme pocket through hydrogen bonds with glycine-253, leucine-251, and threonine-242. It induces the release of NRG1 and promotes the differentiation of neural stem cells into neurons. (8R)-8-Hydroxyepoxyboetirane A holds potential for research into nervous system disorders.Forma y color:Odour SolidTASP0415914
CAS:TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). TFórmula:C13H17N5O3SPureza:98.14%Forma y color:SolidPeso molecular:323.37Ref: TM-T7879
1mg55,00€5mg117,00€10mg187,00€25mg315,00€50mg449,00€100mg620,00€200mg835,00€1mL*10mM (DMSO)134,00€Orbofiban TFA
CAS:Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFórmula:C19H24F3N5O6Pureza:97.45% - 98.43%Forma y color:SolidPeso molecular:475.42HSP27 inhibitor J2
CAS:HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function ofFórmula:C13H12O4SPureza:99.51%Forma y color:SolidPeso molecular:264.3Ref: TM-T7265
1mg130,00€2mg185,00€5mg311,00€10mg472,00€25mg753,00€50mg1.064,00€100mg1.415,00€1mL*10mM (DMSO)455,00€Firategrast
CAS:Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervousFórmula:C27H27F2NO6Pureza:99.16%Forma y color:SolidPeso molecular:499.5Ref: TM-TQ0291
1mg47,00€5mg87,00€10mg140,00€25mg283,00€50mg464,00€100mg747,00€200mg1.017,00€1mL*10mM (DMSO)97,00€Vevorisertib trihydrochloride
CAS:Vevorisertib trihydrochloride (ARQ 751 trihydrochloride) is ainhibitor of pan-AKT and AKT1-E17K mutations, inhibiting AKT1, AKT2 and AKT3.Fórmula:C35H41Cl3N8OPureza:98.28%Forma y color:SolidPeso molecular:696.12Ref: TM-T38846
1mg70,00€5mg149,00€10mg230,00€25mg393,00€50mg552,00€100mg740,00€200mg1.130,00€1mL*10mM (DMSO)212,00€Teprenone
CAS:Teprenone (Geranylgeranylacetone) is a anti-ulcer drug, and works as an inducer of heat shock proteins (HSPs).Fórmula:C23H38OPureza:99.76% - 99.96%Forma y color:SolidPeso molecular:330.55FAK-IN-14
CAS:FAK-IN-14 is a FAK inhibitor that induces apoptosis and cell cycle arrest. FAK-IN-14 has a more significant inhibitory effect on FAK, FGFR1 and Pyk2.Fórmula:C21H24BrN7OSPureza:99.7%Forma y color:SoildPeso molecular:502.43BNC105
CAS:BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.Fórmula:C20H20O7Pureza:96.57%Forma y color:SolidPeso molecular:372.37Ref: TM-T14694
1mg84,00€5mg160,00€10mg226,00€25mg371,00€50mg520,00€100mg702,00€200mg944,00€1mL*10mM (DMSO)170,00€Teclistamab
CAS:Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.Pureza:95%Forma y color:LiquidPentachloropseudilin
CAS:Pentachloropseudilin inhibits Myosin-1 and speeds up TGF-β receptor turnover, suppressing TGF-β activity.Fórmula:C10H4Cl5NOPureza:98.14%Forma y color:SolidPeso molecular:331.41PF-562271
CAS:PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).Fórmula:C21H20F3N7O3SPureza:100% - 97.65%Forma y color:SolidPeso molecular:507.49Ref: TM-T2465
1mg59,00€5mg127,00€10mg159,00€25mg240,00€50mg378,00€100mg567,00€200mg793,00€1mL*10mM (DMSO)140,00€Akt1 and Akt2-IN-1
CAS:Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50=3.5 nM) and Akt2 (IC50=42 nM). It has potent and balanced activity.Fórmula:C33H29N7OForma y color:SolidPeso molecular:539.63cSRC/BCR-ABL-IN-1
cSRC/BCR-ABL-IN-1 (compound 21b) is a potent inhibitor of Bcr-Abl and C-Src, with IC50 values of 56.2 nM and 101 nM, respectively. It exhibits cytotoxicity.Fórmula:C29H31Cl2N5O4Peso molecular:584.494ε-V1-2, Cys-conjugated
Epsilon-V1-2, a Cys-conjugated, is a biologically active peptide known as the εPKC-specific inhibitor.Fórmula:C40H70N10O14SPureza:98%Forma y color:SolidPeso molecular:947.11Miltefosine
CAS:Miltefosine (HePC), effective oral drug for both visceral and cutaneous leishmaniasis, in clinical trials worldwide.Fórmula:C21H46NO4PPureza:98% - 99.87%Forma y color:White To Off-White PowderPeso molecular:407.57SMTIN-T140
CAS:SMTIN-T140: strong TRAP1 inhibitor, IC50=1.646μM, anticancer; disrupts mitochondria, boosts ROS, activates AMPK, shrinks PC3 tumors, no in vivo toxicity.Fórmula:C36H34BrClFN5OPPureza:98%Forma y color:SolidPeso molecular:718.02HA-100
CAS:HA-100 is an inhibitor of protein kinaseFórmula:C13H15N3O2SPureza:99.44%Forma y color:Pale Yellow Crystalline SolidPeso molecular:277.3420-HETE
CAS:20-HETE is a CYP450 product, vasoconstrictor, modulates K+ channels, affects NADPH, ROS, NF-κB, NO synthase, and cell apoptosis/proliferation.Fórmula:C20H32O3Pureza:99.79%Forma y color:SolidPeso molecular:320.47Ref: TM-T14021
1mg (312.04μM*10mL in Ethanol)1.139,00€5mg (312.04μM*50mL in Ethanol)2.327,00€100μg (312.04μM*1mL in Ethanol)474,00€PKCiota-IN-2
CAS:PKCiota-IN-2 selectively inhibits PKC-ι (IC50=2.8nM) and also blocks PKC-α, ε (IC50s=71nM, 350nM).Fórmula:C24H21N5OPureza:99.74%Forma y color:SolidPeso molecular:395.46Ref: TM-T9863
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€1mL*10mM (DMSO)279,00€(E)-Akt inhibitor-IV
CAS:(E)-Akt inhibitor-IV ((E)-AKTIV) ((E)-AKTIV) is an inhibitor of PI3K-Akt.Fórmula:C31H29IN4SPureza:99.01% - 99.74%Forma y color:SolidPeso molecular:616.56Ref: TM-T9393
1mg55,00€5mg116,00€10mg180,00€25mg338,00€50mg469,00€100mg655,00€200mg924,00€1mL*10mM (DMSO)157,00€Eupalinolide A
CAS:Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines.Fórmula:C24H30O9Pureza:98.18% - 99.22%Forma y color:SolidPeso molecular:462.49Taurochenodeoxycholic acid sodium
CAS:Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).Fórmula:C26H44NNaO6SPureza:98.23% - 99.45%Forma y color:White To Off-White PowderPeso molecular:521.68Arimoclomol maleate
CAS:Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.Fórmula:C18H24ClN3O7Pureza:99.9% - 99.98%Forma y color:SolidPeso molecular:429.85Ombrabulin hydrochloride
CAS:Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells andFórmula:C21H27ClN2O6Pureza:98%Forma y color:SolidPeso molecular:438.9Roslin 2 bromide
CAS:Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that disrupts the binding of FAK and p5.Fórmula:C13H19BrN4Pureza:97.07%Forma y color:SolidPeso molecular:311.22
