Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Productos de "Señalización citoesquelética"
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FRAX486
CAS:FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.Fórmula:C25H23Cl2FN6OPureza:98.81%Forma y color:SolidPeso molecular:513.39AKT-IN-26
CAS:AKT-IN-26 (Compound 453) is an AKT inhibitor that binds to the Pleckstrin Homology (PH) domain of AKT. It is useful for research related to cell proliferation and cancer involving the AKT pathway.Fórmula:C21H17N5O4SForma y color:SolidPeso molecular:435.456JG-231
CAS:JG-231, a JG-98 analog, shows anticancer properties by blocking Hsp70-BAG3 interaction and hindering TNBC in MDA-MB-231 models.Fórmula:C22H18BrCl2N3OS4Pureza:99.21%Forma y color:SolidPeso molecular:619.47TN-16
CAS:TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 μM)Fórmula:C19H18N2O2Pureza:99.54%Forma y color:SolidPeso molecular:306.36LXW7
CAS:LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (Fórmula:C29H48N12O12S2Pureza:100%Forma y color:SolidPeso molecular:820.89Batatasin III
CAS:Batatasin III inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition and FAK-AKT signals and possesses anti-cancerFórmula:C15H16O3Pureza:99.16%Forma y color:SolidPeso molecular:244.29HM03
CAS:HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.Fórmula:C26H27ClN4O2Pureza:97.15%Forma y color:SolidPeso molecular:462.97AT7867
CAS:AT7867 inhibits Akt1/2/3 & p70S6K/PKA (IC50: 32/17/47 nM & 85/20 nM), minimal effect beyond AGC kinases.Fórmula:C20H20ClN3Pureza:99.63%Forma y color:SolidPeso molecular:337.85Ref: TM-T6304
2mg44,00€5mg65,00€10mg86,00€25mg135,00€50mg210,00€100mg313,00€200mg452,00€1mL*10mM (DMSO)65,00€2-Methylbutyrylcarnitine chloride
2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating the activation of cytosolic phospholipase A2 (cPLA2) and enhancing platelet hyperresponsiveness. This compound further augments platelet hyperreactivity and promotes thrombus formation in mice. It is also characterized as a branched-chain acylcarnitine.Fórmula:C12H24ClNO4Forma y color:SolidPeso molecular:281.78Arginine-glycine-aspartic acid
CAS:RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.Fórmula:C12H22N6O6Pureza:99.11%Forma y color:SolidPeso molecular:346.34Valategrast hydrochloride
CAS:Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.Fórmula:C30H33Cl4N3O4Pureza:98%Forma y color:SolidPeso molecular:641.41Irigenin
CAS:Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the ExtraFórmula:C18H16O8Pureza:99.50% - 99.85%Forma y color:SolidPeso molecular:360.31Afuresertib hydrochloride
CAS:Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)Fórmula:C18H18Cl3FN4OSPureza:99.96%Forma y color:SolidPeso molecular:463.8Ref: TM-T7885
2mg52,00€5mg74,00€10mg95,00€25mg163,00€50mg253,00€100mg437,00€200mg568,00€1mL*10mM (DMSO)86,00€Bersanlimab
CAS:Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.Pureza:> 95% - > 95%Forma y color:LiquidPeso molecular:144.22 kDaDolastatin 10
CAS:Dolastatin 10 (DLS 10) is a powerful peptide with antimitotic properties, effectively inhibiting tubulin polymerization.Fórmula:C42H68N6O6SPureza:99.55%Forma y color:SolidPeso molecular:785.09Shepherdin 79-87 acetate
Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.Fórmula:C43H68N12O14SPureza:98.08%Forma y color:SolidPeso molecular:1009.14G-5555
CAS:G-5555 is a potent inhibitor of p21-activated kinase 1 (PAK1) (Kis: 3.7 nM and 11 nM for PAK1 and PAK2, respectively).Fórmula:C25H25ClN6O3Pureza:99.76% - 99.87%Forma y color:SolidPeso molecular:492.96Flumatinib
CAS:Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.Fórmula:C29H29F3N8OPureza:99.52% - 99.95%Forma y color:SolidPeso molecular:562.59Ref: TM-T4320
1mg35,00€5mg66,00€10mg87,00€25mg127,00€50mg163,00€100mg273,00€200mg409,00€500mg677,00€1mL*10mM (DMSO)87,00€Betamethasone 17-benzoate
CAS:Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).Fórmula:C29H33FO6Pureza:98%Forma y color:SolidPeso molecular:496.57EC 144
CAS:EC 144, a second-generation selective inhibitor of Hsp90 , inhibits tumor growth for Hsp90α and degradation of Her-2 in MCF-7 cells.Fórmula:C21H24ClN5O2Forma y color:SolidPeso molecular:413.9BRD9876
CAS:BRD9876 is a selective inhibitor of MM1S growth.Fórmula:C16H14N2Pureza:97.81%Forma y color:SolidPeso molecular:234.3FAK-IN-15
FAK-IN-15 is a highly potent focal adhesion kinase (FAK) inhibitor with antitumor activity.Fórmula:C21H24ClN7OSPureza:99.08%Forma y color:SolidPeso molecular:457.98Palmitic acid
CAS:Palmitic acid (Cetylic acid) is a natural product, a common saturated fatty acid found in animals, plants and microorganisms.Fórmula:C16H32O2Pureza:99.17% - 99.67%Forma y color:White Crystalline Scales SolidPeso molecular:256.42Cyclo(RADfK)
CAS:Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.Fórmula:C28H43N9O7Pureza:100%Forma y color:SolidPeso molecular:617.7Auristatin F
CAS:Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.Fórmula:C40H67N5O8Pureza:98.41% - 99.25%Forma y color:SolidPeso molecular:745.99AM-5308
CAS:AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.Fórmula:C26H35N5O5SPureza:98.06% - 99.58%Forma y color:SolidPeso molecular:529.65MMAF
CAS:MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.Fórmula:C39H65N5O8Pureza:97.00%Forma y color:SolidPeso molecular:731.96GRGDSPK
CAS:GRGDSPK (EMD 56574) is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.Fórmula:C28H49N11O11Pureza:98%Forma y color:SolidPeso molecular:715.76Amiprofos methyl
CAS:Amiprofos methyl (BAY-NTN 6867) is an organophosphorus herbicide that specifically and competitively inhibits microtubule polymerization in plant cells.Fórmula:C11H17N2O4PSPureza:99.66%Forma y color:SolidPeso molecular:304.3Elarofiban
CAS:Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.Fórmula:C22H32N4O4Pureza:99.94%Forma y color:SolidPeso molecular:416.51cemadotin free base
CAS:Cemadotin free base(LU103793 free base) is a novel anti-limiting peptide , an analog of Dolastatin 15, a naturally occurring cytotoxic peptide that blocksFórmula:C35H56N6O5Pureza:99% - 99.69%Forma y color:SolidPeso molecular:640.86JH-VIII-157-02
CAS:JH-VIII-157-02 inhibits ALK, specifically EML4-ALK variants, with IC50s of 2 nM.Fórmula:C28H27N5O2Pureza:98.02%Forma y color:SolidPeso molecular:465.55Ref: TM-T15612
1mg116,00€5mg240,00€10mg358,00€25mg558,00€50mg753,00€100mg1.035,00€1mL*10mM (DMSO)246,00€N-Desmethyltamoxifen hydrochloride
CAS:N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.Fórmula:C25H28ClNOPureza:99.15%Forma y color:SolidPeso molecular:393.95Ref: TM-T12148
2mg35,00€5mg52,00€10mg78,00€25mg139,00€50mg202,00€100mg305,00€200mg426,00€1mL*10mM (DMSO)52,00€Dasatinib monohydrate
CAS:Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Fórmula:C22H28ClN7O3SPureza:100% - 99.68%Forma y color:SolidPeso molecular:506.03Bisindolylmaleimide I
CAS:Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.Fórmula:C25H24N4O2Pureza:98.19% - 99.08%Forma y color:Orange SolidPeso molecular:412.48C086
CAS:C086 is a novel and potent Hsp90 inhibitor that suppresses cell cycle progression, induces apoptosis, and exhibits anti-metastatic properties by modulating various mechanisms in different cell types.Fórmula:C29H28O8Forma y color:SolidPeso molecular:504.53Mertansine
CAS:Mertansine is a tubulin inhibitor and an antibody-conjugable maytansinoid alkaloid. The IC50 of Mertansine against HCT-15 and A431 cells is 0.750 and 0.04nM.Cost-effective and quality-assured.Fórmula:C35H48ClN3O10SPureza:100% - 99.76%Forma y color:SolidPeso molecular:738.29SB273005
CAS:SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.Fórmula:C22H24F3N3O4Pureza:99.58%Forma y color:SolidPeso molecular:451.44Dynasore
CAS:Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.Fórmula:C18H14N2O4Pureza:95.85% - 99.22%Forma y color:SolidPeso molecular:322.31Ref: TM-T1848
5mg49,00€10mg79,00€25mg140,00€50mg259,00€100mg374,00€200mg560,00€500mg883,00€1mL*10mM (DMSO)87,00€c-ABL-IN-5
C-ABL-IN-5, a selective c-Abl inhibitor, exhibits neuroprotective properties and has favorable characteristics including blood-brain barrier permeability,Fórmula:C19H17F2N3OPureza:98%Forma y color:SolidPeso molecular:341.35KIF18A-IN-14
CAS:KIF18A-IN-14 (Compound Example 81) is an inhibitor of KIF18A that exists in two forms, EX81-A and its enantiomer EX81-B. EX81-A and EX81-B inhibit the viability of OVCAR-3 cells with IC50 values of 0-0.01 μM and 0.01-0.1 μM, respectively. KIF18A-IN-14 can be utilized in tumor research, including studies on colon cancer, breast cancer, and lung cancer.Fórmula:C26H32F3N5O6SForma y color:SolidPeso molecular:599.62REDV TFA
REDV TFA, the minimal active sequence of the CS5 site in the alternatively spliced type III connecting segment (IIICS) of fibronectin, mediates adhesion to theFórmula:C20H35N7O9·xC2HF3O2Pureza:98%Forma y color:SolidPeso molecular:517.53 (free acid)Lyn-IN-1
CAS:Lyn-IN-1 (Bafetinib analog) is a selective and potent dual inhibitor of Bcr-Abl and LynFórmula:C30H31F3N8OPureza:97% - 99.33%Forma y color:SolidPeso molecular:576.62Ref: TM-T11916
1mg47,00€2mg56,00€5mg84,00€10mg124,00€25mg250,00€50mg393,00€100mg560,00€200mg815,00€1mL*10mM (DMSO)97,00€PVZB1194
CAS:PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis throughFórmula:C13H9F4NO2SPureza:98%Forma y color:SolidPeso molecular:319.28Defactinib analogue-1
CAS:Defactinib analogue-1 (Compound 7) serves as a ligand for the target protein FAK, and is utilized in the synthesis of PROTAC FAK degrader 1.Fórmula:C20H20F3N5O3SForma y color:SolidPeso molecular:467.47Tubulysin D
CAS:Tubulysin D is a tetrapeptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and displays potent antitumor activity.Fórmula:C43H65N5O9SPureza:98%Forma y color:SolidPeso molecular:828.07Triciribine
CAS:Triciribine (NSC-154020) is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2.Fórmula:C13H16N6O4Pureza:99.01% - 99.87%Forma y color:SolidPeso molecular:320.3Ref: TM-T6065
1mg43,00€2mg57,00€5mg93,00€10mg135,00€25mg236,00€50mg394,00€100mg588,00€1mL*10mM (DMSO)93,00€S516
CAS:S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.Fórmula:C21H19N5O4SPureza:98%Forma y color:SolidPeso molecular:437.47Nic-15
CAS:Nic-15 (compound 4n) serves as an anti-constrictive agent targeting the low vascular characteristics of pancreatic tumors. These characteristics enable cancer cells to adapt to the nutrient-deficient tumor microenvironment and develop resistance to treatment. Nic-15 modulates the PI3K/Akt/mTOR pathway and alleviates ER stress induced by Gemcitabine. It significantly inhibits migration and colony formation in MIA PaCa-2 and PANC-1 pancreatic cancer cells. When used in combination with Gemcitabine, Nic-15 effectively addresses resistance issues in pancreatic tumors. In xenograft models in vivo, Nic-15 notably enhances the efficacy of Gemcitabine.Fórmula:C25H26F2O3Forma y color:SolidPeso molecular:412.47Dasatinib N-oxide
CAS:Dasatinib N-oxide is a key metabolite and potential impurity of the kinase inhibitor dasatinib.Fórmula:C22H26ClN7O3SPureza:98.54% - 99.85%Forma y color:SolidPeso molecular:504Tubulin inhibitor 6
CAS:Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.Fórmula:C20H14ClNO2SPureza:99.05%Forma y color:SolidPeso molecular:367.85Ref: TM-T13224
5mg50,00€10mg80,00€25mg117,00€50mg170,00€100mg259,00€200mg369,00€1mL*10mM (DMSO)51,00€PKC-θ inhibitor 1
CAS:PKC-theta inhibitor 1 is an inhibitor of PKCθ (Ki of 6 nM)Fórmula:C17H15F3N4OPureza:98%Forma y color:SolidPeso molecular:348.32FGFRs-IN-1
FGFRs-IN-1 (Compound A16) is an orally active inhibitor targeting FGFR1/2/3/4, with IC50 values of 2.3, 7, 11, and 163 nM respectively. It also inhibits VEGFR1/2/3, Abl, and Flt3, with IC50 values of 61, 176, 112, 26, and 353 nM. The compound shows weak inhibition of CYP enzymes. FGFRs-IN-1 reduces the expression of α-SMA and collagen I, and it inhibits epithelial-mesenchymal transition (EMT) in A549 cells stimulated by TGF-β1. Additionally, FGFRs-IN-1 demonstrates anti-inflammatory activity in mouse models of lung fibrosis induced by Bleomycin and liver fibrosis induced by CCl4.Fórmula:C28H26Cl2N4O3Forma y color:SolidPeso molecular:537.44HSP90-IN-27
CAS:HSP90-IN-27, also known as compound 19, is an inhibitor of HSP90 [1].Fórmula:C18H21N3O2SPureza:98%Forma y color:SolidPeso molecular:343.44PF-431396
CAS:PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).Fórmula:C22H21F3N6O3SPureza:98.83% - 99.82%Forma y color:SolidPeso molecular:506.5Dynole 34-2
CAS:Dynole 34-2 is a non-competitive inhibitor of dynamin1 and dynamin2 GTPases that inhibits receptor-mediated endocytosis and synaptic vesicle endocytosis.Fórmula:C25H36N4OPureza:99.61%Forma y color:SolidPeso molecular:408.58Tonabersat
CAS:Tonabersat (SB-220453) is a novel and orally available gap-junction modulator and CSD (Cortical spreading depression) inhibitor that,migraine and epilepsy.Fórmula:C20H19ClFNO4Pureza:99.49%Forma y color:SolidPeso molecular:391.82Uprosertib
CAS:Uprosertib (GSK2141795) is a potent, selective Akt broad-spectrum inhibitor for Akt1/Akt2/Akt3.Cost-effective and quality-assured.Fórmula:C18H16Cl2F2N4O2Pureza:95.62% - 99.54%Forma y color:SolidPeso molecular:429.25Ref: TM-T6849
1mg47,00€2mg59,00€5mg85,00€10mg124,00€25mg202,00€50mg324,00€100mg535,00€200mg752,00€1mL*10mM (DMSO)108,00€Xentuzumab
CAS:Xentuzumab (BI836845) is a recombinant monoclonal antibody to humanised IGF ligand that inhibits AKT activation and can be used to study solid tumours.Pureza:95% - > 95%Forma y color:LiquidPeso molecular:143.7 kDaEV206
CAS:EV206 is an effective inhibitor of Hsp70, exhibiting antiproliferative properties. This compound induces cell apoptosis (apoptosis) and enhances the protein expression of cleaved PARP and caspase-3. Additionally, EV206 demonstrates antitumor activity.Fórmula:C21H19N3OForma y color:SolidPeso molecular:329.40ILK-IN-3
CAS:ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.Fórmula:C10H12N6OPureza:99.69%Forma y color:SolidPeso molecular:232.24(±)-1,2-Diolein
CAS:(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.Fórmula:C39H72O5Forma y color:SolidPeso molecular:620.99Alvespimycin
CAS:Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.Fórmula:C32H48N4O8Pureza:100%Forma y color:SolidPeso molecular:616.75IIQLPEIVVV TFA
IIQLPEIVVV TFA serves as a specific inhibitor targeting the Drp1-Mff interaction. This compound discriminates between physiological and pathological fission, hindering physiological fission which leads to mitochondrial dysfunction. IIQLPEIVVV TFA is also utilized in research related to Huntington's disease.Fórmula:C54H95N11O14·xC2HF3O2Forma y color:SolidPeso molecular:1122.40 (free base)Tyrosine kinase-IN-9
CAS:Tyrosine kinase-IN-9 (Compound B) is an inhibitor of c-Abl. It is useful for studying neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.Fórmula:C20H14ClN3O3Forma y color:SolidPeso molecular:379.796PF-03814735
CAS:PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.Fórmula:C23H25F3N6O2Pureza:98%Forma y color:SolidPeso molecular:474.48Tirofiban
CAS:Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.Fórmula:C22H36N2O5SPureza:99.87%Forma y color:SolidPeso molecular:440.63-Hydroxyxanthone
CAS:3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical veinFórmula:C13H8O3Pureza:98%Forma y color:SolidPeso molecular:212.2NPX800
CAS:NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in studies about the treatment of cancer.Fórmula:C32H32FN5O4Pureza:99.26%Forma y color:SolidPeso molecular:569.63Ref: TM-T9804
1mg96,00€5mg240,00€10mg375,00€25mg627,00€50mg893,00€100mg1.216,00€1mL*10mM (DMSO)300,00€AKT-IN-6
CAS:AKT-IN-6 (INCB-047775) inhibits Akt, a key signaling protein linked to type 2 diabetes and cancer.Fórmula:C22H20FN5OPureza:98.83%Forma y color:SolidPeso molecular:389.43Ref: TM-T36310
1mg35,00€5mg74,00€10mg111,00€25mg216,00€50mg354,00€100mg567,00€200mg805,00€1mL*10mM (DMSO)84,00€Radicicol
CAS:Radicicol is an antifungal antibiotic, a inhibitor of Hsp90 & FTO, Anti-malarial , inhibits iNOS gene expression by blocking the p38 kinase and NF-κB/Rel.Fórmula:C18H17ClO6Pureza:98%Forma y color:White/Yellow PowderPeso molecular:364.78Phorbol 12-myristate 13-acetate
CAS:Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.Fórmula:C36H56O8Pureza:100% - 99.5%Forma y color:White To Off-White SolidPeso molecular:616.83Eg5 Inhibitor V, trans-24
CAS:Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.Fórmula:C26H21N3O3Pureza:97.45%Forma y color:SolidPeso molecular:423.46Ref: TM-T11155
1mg92,00€5mg205,00€10mg305,00€25mg495,00€50mg677,00€100mg905,00€200mg1.216,00€1mL*10mM (DMSO)227,00€A-286982
CAS:A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.Fórmula:C24H27N3O4SPureza:97.81%Forma y color:SolidPeso molecular:453.55Ref: TM-T21781
1mg35,00€2mg50,00€5mg74,00€10mg107,00€25mg210,00€50mg350,00€100mg522,00€1mL*10mM (DMSO)81,00€BX517
CAS:BX517 (PDK1 inhibitor 2) is a potent and selective inhibitor of PDK1.Fórmula:C15H14N4O2Pureza:99.07%Forma y color:SolidPeso molecular:282.3DTHIB
CAS:DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.Fórmula:C13H9ClFN3O3Pureza:98.86% - 99.29%Forma y color:SolidPeso molecular:309.68Ref: TM-T8858
1mg35,00€5mg70,00€10mg104,00€25mg210,00€50mg338,00€100mg540,00€500mg1.130,00€1mL*10mM (DMSO)78,00€AN-019
CAS:AN-019 (NRC-019) is a Bcr-Abl kinase inhibitor with antitumor activity for the study of chronic myelogenous leukemia (CML) and breast cancer.Fórmula:C25H17F6N5OPureza:98.01%Forma y color:SolidPeso molecular:517.43ZIP acetate(863987-12-6 free base)
ZIP acetate inhibits PKMζ (protein kinase Mζ), affecting LTP maintenance and spatial memory, with an IC50 of 1-2.5 μM.Fórmula:C92H158N30O19Pureza:94.68%Forma y color:SolidPeso molecular:1988.43Tilavonemab
CAS:Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.Pureza:95% - 95%Forma y color:LiquidSuprafenacine
CAS:Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that inducesFórmula:C16H18N4OPureza:99.72%Forma y color:SolidPeso molecular:282.34GRGDSP acetate(91037-75-1 free base)
GRGDSP acetate(91037-75-1 free base) is a synthetic linear RGD peptide and is an integrin inhibitor.Fórmula:C24H41N9O12Pureza:99.77%Forma y color:SolidPeso molecular:647.64Auristatin E
CAS:Auristatin E, MMAE analog, blocks tubulin polymerisation, has cytotoxic and potent antitumor effects, used in ADCs.Fórmula:C40H69N5O7Pureza:98.81%Forma y color:SolidPeso molecular:732.01SB-216
CAS:SB-216, a potent anti-cancer compound, inhibits tubulin polymerization and curbs growth in various cancer cells.Fórmula:C17H18N4O2Pureza:100%Forma y color:SolidPeso molecular:310.35Ref: TM-T60757
1mg54,00€5mg116,00€10mg188,00€25mg331,00€50mg475,00€100mg655,00€1mL*10mM (DMSO)133,00€Dynamin inhibitory peptide, myristoylated acetate
Myristoylated acetate peptide inhibits DynaMin, blocking amphiphysin binding; myristoylated TFA variant hinders endocytosis.Fórmula:C63H111N19O16Pureza:99.42%Forma y color:SolidPeso molecular:1390.67SC-10
CAS:SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.Fórmula:C17H22ClNO2SPureza:99.24% - 99.58%Forma y color:SolidPeso molecular:339.88GRP78-IN-3
CAS:GRP78-IN-3: Potent Hsp70 blocker, selective Grp78 (HSPA5) inhib., IC50 0.59 μM, 7x more vs HspA9, 20x vs HspA2.Fórmula:C17H18N4O2SPureza:99.11%Forma y color:SoildPeso molecular:342.42ALK inhibitor 1
CAS:ALK inhibitor 1 is a selective ALK kinase inhibitor.Fórmula:C23H28BrN7O3SPureza:98.27%Forma y color:SolidPeso molecular:562.48Ref: TM-T10285
1mg52,00€5mg116,00€10mg170,00€25mg340,00€50mg472,00€100mg645,00€1mL*10mM (DMSO)143,00€KIF18A-IN-3
CAS:KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.Fórmula:C28H38N4O5S2Pureza:98.45%Forma y color:SolidPeso molecular:574.76Combretastatin A-1
CAS:Combretastatin A-1 is a microtubule inhibitor with anti-tumour and can be used to study liver cancer.Fórmula:C18H20O6Pureza:97.49% - 97.49%Forma y color:SolidPeso molecular:332.35Lifitegrast
CAS:Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.Fórmula:C29H24Cl2N2O7SPureza:99.39% - 99.66%Forma y color:SolidPeso molecular:615.48CGP 53353
CAS:CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.Fórmula:C20H13F2N3O2Pureza:98.11%Forma y color:SolidPeso molecular:365.33PKC-θ inhibitor
CAS:PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.Fórmula:C20H25F3N6O3Pureza:98%Forma y color:SolidPeso molecular:454.45Ref: TM-T5423
1mg106,00€5mg250,00€10mg329,00€25mg467,00€50mg612,00€100mg944,00€200mg1.264,00€1mL*10mM (DMSO)274,00€Borussertib
CAS:Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt(IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt)Fórmula:C36H32N6O3Pureza:99.00%Forma y color:SolidPeso molecular:596.68Ref: TM-T8427
1mg133,00€5mg274,00€10mg432,00€25mg715,00€50mg1.008,00€100mg1.359,00€1mL*10mM (DMSO)360,00€FAK-IN-11
FAK-IN-11 (Compound 4l), a FAK inhibitor, specifically targets the ATP binding pocket of FAK to prevent its phosphorylation.Fórmula:C25H41NO3Pureza:98%Forma y color:SolidPeso molecular:403.6Tirbanibulin Mesylate
CAS:Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Fórmula:C27H33N3O6SPureza:99.42%Forma y color:SolidPeso molecular:527.63Ref: TM-T15675
2mg38,00€5mg56,00€10mg70,00€25mg126,00€50mg243,00€100mg416,00€200mg562,00€1mL*10mM (DMSO)65,00€IPI-493
CAS:IPI-493 is a bioactive chemical.Fórmula:C28H39N3O8Pureza:100%Forma y color:SolidPeso molecular:545.62WAY-118959-A
CAS:WAY-118959-A is a potential microtubule acetylation inhibitor.Fórmula:C16H14N4OS2Pureza:99.86%Forma y color:SolidPeso molecular:342.44Ref: TM-T60065
1mg115,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€200mg1.454,00€1mL*10mM (DMSO)261,00€Sangivamycin
CAS:Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.Fórmula:C12H15N5O5Pureza:98.11%Forma y color:SolidPeso molecular:309.28Ref: TM-T9605
1mg126,00€5mg274,00€10mg416,00€25mg677,00€50mg944,00€100mg1.264,00€1mL*10mM (DMSO)360,00€AKT-IN-2
CAS:AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).Fórmula:C25H34F3N7OPureza:98%Forma y color:SolidPeso molecular:505.583CAI
CAS:3CAI inhibits AKT1/2, reduces mTOR/GSK3β, and triggers apoptosis in colon cancer cells.Fórmula:C10H8ClNOPureza:98.13%Forma y color:SolidPeso molecular:193.63Ref: TM-T14034
5mg55,00€10mg77,00€25mg125,00€50mg220,00€100mg330,00€200mg485,00€500mg787,00€1mL*10mM (DMSO)64,00€
