Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Productos de "Señalización citoesquelética"
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NVS-PAK1-1
CAS:NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).Fórmula:C23H25ClF3N5OPureza:99.35%Forma y color:SolidPeso molecular:479.93Volociximab
CAS:Volociximab (M200) is an IgG4 monoclonal antibody targeting the α5β1 integrin , with antiangiogenic, antitumor and anticancer activity, inhibits the growth of rabbit VX2 tumors and is used to study solid tumors.Pureza:95%Forma y color:Liquid2119738-71-3
CAS:Compound 2119738-71-3 interacts with the FAK receptor.Fórmula:C25H29ClFN7O2Pureza:98%Forma y color:SolidPeso molecular:513.99AD57
CAS:AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.Fórmula:C22H20F3N7OPureza:98.23%Forma y color:SoildPeso molecular:455.44Ref: TM-T22552L
1mg34,00€2mg52,00€5mg116,00€10mg212,00€25mg359,00€50mg512,00€100mg695,00€200mg939,00€1mL*10mM (DMSO)134,00€Fasudil
CAS:Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Fórmula:C14H17N3O2SPureza:99.79% - 99.84%Forma y color:SolidPeso molecular:291.37PKCη pseudosubstrate inhibitor,myristoylated
CAS:Myristoylated PKCη pseudosubstrate inhibitor is a cell-permeable compound utilized to investigate the mechanism of action of PKCη [1].Fórmula:C101H185N41O23SPureza:98%Forma y color:SolidPeso molecular:2373.88Dynamin IN-2
CAS:Dynamin IN-2 (compound 43) is a Wiskostatin analogue.Fórmula:C22H21ClN2OPureza:98.81% - 98.83%Forma y color:SoildPeso molecular:364.87Ref: TM-T64369
1mg140,00€5mg331,00€10mg439,00€25mg667,00€50mg894,00€100mg1.198,00€200mg1.596,00€1mL*10mM (DMSO)341,00€Ifebemtinib hydrochloride
Ifebemtinib (BI-853520) hydrochloride is a potent FAK (focal adhesion kinase) inhibitor with oral bioavailability, exhibiting an IC50 of 1 nM for recombinant FAK. Ifebemtinib hydrochloride demonstrates antiproliferative activity against cancer cells.Fórmula:C28H29ClF4N6O4Forma y color:SolidPeso molecular:625.01Ponatinib
CAS:Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFórmula:C29H27F3N6OPureza:98% - 99.60%Forma y color:SolidPeso molecular:532.56Compound 1T-0219 (SC)
CAS:Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620Fórmula:C20H19N3O7Pureza:90%Forma y color:SolidPeso molecular:413.38PF-AKT400
CAS:PF-AKT400 (AKT protein kinase inhibitor) is a broadly selective and ATP-competitive inhibitor of Akt.Fórmula:C20H22F2N6OPureza:98.21%Forma y color:SolidPeso molecular:400.43Ref: TM-T5508
1mg95,00€5mg227,00€10mg325,00€25mg550,00€50mg787,00€100mg1.093,00€1mL*10mM (DMSO)250,00€BIO-1211
CAS:BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).Fórmula:C36H48N6O9Pureza:99.33%Forma y color:SolidPeso molecular:708.8D-ERYTHRO-SPHINGOSINE
CAS:D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activatorFórmula:C18H37NO2Pureza:98% - ≥98%Forma y color:SolidPeso molecular:299.49Arimoclomol
CAS:Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (Fórmula:C14H20ClN3O3Pureza:99.81%Forma y color:SolidPeso molecular:313.78Ref: TM-T13553
1mg115,00€5mg249,00€10mg369,00€25mg562,00€50mg787,00€100mg1.054,00€200mg1.406,00€1mL*10mM (DMSO)249,00€Taurolithocholic acid sodium salt
CAS:Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, butFórmula:C26H44NNaO5SPureza:99.79% - 99.93%Forma y color:SolidPeso molecular:505.69Indatuximab
Indatuximab is a chimeric antibody targeting CD13, used in the synthesis of ADC compound Indatuximab ravtansine.Forma y color:LiquidPeso molecular:145.5 kDaBalamapimod
CAS:Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.Fórmula:C30H32ClN7OSPureza:98%Forma y color:SolidPeso molecular:574.14AG1024
CAS:AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).Fórmula:C14H13BrN2OPureza:98% - 99.37%Forma y color:SolidPeso molecular:305.17Tirbanibulin
CAS:Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Fórmula:C26H29N3O3Pureza:99.43% - 99.67%Forma y color:SolidPeso molecular:431.53Ref: TM-T6345
1mg35,00€5mg66,00€10mg81,00€25mg159,00€50mg280,00€100mg470,00€500mg1.035,00€1mL*10mM (DMSO)70,00€BMS-688521
CAS:BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.Fórmula:C26H19Cl2N5O4Pureza:98.87%Forma y color:SolidPeso molecular:536.37Ref: TM-T14676
1mg183,00€5mg464,00€10mg655,00€25mg1.169,00€50mg1.539,00€100mg1.882,00€1mL*10mM (DMSO)547,00€AT-533
CAS:AT-533 inhibits Hsp90, HSV, hinders HIF-1α/VEGF/VEGFR-2, Erk1/2, FAK, Akt/mTOR/p70S6K, and blocks tumor growth, angiogenesis, and HUVEC activities.Fórmula:C23H30N4O3Pureza:99.54%Forma y color:SoildPeso molecular:410.51Ref: TM-T67836
1mg51,00€5mg111,00€10mg170,00€25mg313,00€50mg467,00€100mg672,00€200mg905,00€1mL*10mM (DMSO)117,00€Azelaoyl PAF
CAS:Azelaoyl PAF is a potent PPARγ agonist that competitively binds thiazolidinediones.promotes the uptake of oxLDL by macrophages by upregulating CD36 expression.Fórmula:C33H66NO9PForma y color:SolidPeso molecular:651.85BAY1217389
CAS:BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).Fórmula:C27H24F5N5O3Pureza:95.71% - 98.78%Forma y color:SolidPeso molecular:561.5CIB-L43
CAS:CIB-L43 is an orally active TRBP inhibitor (KD = 4.78 nM) that disrupts the TRBP-dicer interaction (IC50 = 2.34 μM). It suppresses the biosynthesis of oncogenic miR-21, elevates PTEN and Smad7 expression, and inhibits AKT and TGF-β signaling, thereby reducing the proliferation and migration of HCC cells.Fórmula:C15H16N2O3SForma y color:SolidPeso molecular:304.364BCR-ABL-IN-8
CAS:BCR-ABL-IN-8 (compound 26f) is a BCR-ABL inhibitor featuring a trimethoxy group [1].Fórmula:C30H33N7O5Pureza:98%Forma y color:SolidPeso molecular:571.63Abciximab
CAS:Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Pureza:SDS-PAGE:95.2%;SEC-HPLC:95.9%Forma y color:LiquidPeso molecular:95.18 kDaVerbascoside
CAS:Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.Fórmula:C29H36O15Pureza:97.46% - 99.55%Forma y color:SolidPeso molecular:624.59ML-B01
ML-B01 is an orally active inhibitor targeting Akt and PKA, with IC50 values of 2 nM and 136 nM, respectively. It demonstrates good blood-brain barrier (BBB) permeability in mice.Fórmula:C24H31Cl2N5OForma y color:SolidPeso molecular:476.44MSN-125
CAS:MSN-125 inhibits Bax/Bak apoptosis, protects neurons, prevents MOMP with IC50 of 4μM.Fórmula:C36H38BrN3O6Pureza:98%Forma y color:SolidPeso molecular:688.61Dihydrocytochalasin B
CAS:Dihydrocytochalasin B (H2CB) is a cell division inhibitor that inhibits cytokinesis and alters cell morphology.Fórmula:C29H39NO5Pureza:98%Forma y color:SolidPeso molecular:481.62Ipatasertib
CAS:Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that can lead to p53-independent PUMA activation.Cost-effective and quality-assured.Fórmula:C24H32ClN5O2Pureza:98.28% - 99.21%Forma y color:SolidPeso molecular:458αVβ8-IN-1
CAS:αVβ8-IN-1 is an inhibitor of the αVβ8 integrin. It exhibits growth-suppressive activity against tumors such as EMT6, CT26, KPC, and TKCC-10. αVβ8-IN-1 is suitable for research related to idiopathic pulmonary fibrosis (IPF), nonspecific interstitial pneumonia (NSIP), and various cancers.Fórmula:C25H32ClN5O4Forma y color:SolidPeso molecular:502.01FRAX486 HCL(1232030-35-1 free base)
FRAX486 HCL is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.Fórmula:C25H24Cl3FN6OPureza:98.85% - 99.82%Forma y color:SolidPeso molecular:549.86Anti-EMMPRIN/CD147 Antibody
Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.Forma y color:Odour LiquidPF-04929113 Mesylate
CAS:PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37Fórmula:C26H34F3N5O7SPureza:99% - 99.46%Forma y color:SolidPeso molecular:617.63Ref: TM-T4342
1mg78,00€2mg100,00€5mg159,00€10mg288,00€25mg419,00€50mg615,00€100mg878,00€500mg1.776,00€1mL*10mM (DMSO)233,00€TCS 21311
CAS:TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.Fórmula:C27H25F3N4O4Pureza:≥98%Forma y color:SolidPeso molecular:526.51Bimosiamose
CAS:Bimosiamose has anti-inflammatory effects[1].Fórmula:C46H54O16Pureza:98%Forma y color:SolidPeso molecular:862.91αvβ1 integrin-IN-1
CAS:αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.Fórmula:C26H34N6O6SPureza:100% - 99.74%Forma y color:SolidPeso molecular:558.65Ref: TM-T13473
1mg115,00€5mg274,00€10mg432,00€25mg697,00€50mg938,00€100mg1.293,00€200mg1.738,00€1mL*10mM (DMSO)349,00€Cilengitide TFA
CAS:Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.Fórmula:C29H41F3N8O9Forma y color:SolidPeso molecular:702.68DB07107
CAS:DB07107 is a potent inhibitor of drug resistant T315I mutant Bcr-Abl tyrosine kinase and a potent Akt1 inhibitor (IC50: 360 nM).Fórmula:C23H22N4OPureza:98%Forma y color:SolidPeso molecular:370.45Estramustine
CAS:Estramustine (LEO-275), a nitrogen mustard-estradiol compound, treats prostate cancer and protects against radiation.Fórmula:C23H31Cl2NO3Pureza:98.09%Forma y color:SolidPeso molecular:440.4Ref: TM-T20681
5mg47,00€10mg70,00€25mg126,00€50mg202,00€100mg329,00€200mg487,00€1mL*10mM (DMSO)50,00€Lifitegrast sodium
CAS:Lifitegrast sodium (SAR-1118-023 sodium) is an integrin antagonist that reduces ocular surface inflammation and can be used to study dry eye.Fórmula:C29H23Cl2N2NaO7SPureza:99.33%Forma y color:SolidPeso molecular:637.46Ro 31-8220 Mesylate
CAS:Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.Fórmula:C25H23N5O2S·CH4O3SPureza:98.79% - 99.02%Forma y color:SolidPeso molecular:553.65Ref: TM-T6643
1mg52,00€2mg67,00€5mg97,00€10mg159,00€25mg244,00€50mg338,00€100mg500,00€1mL*10mM (DMSO)140,00€Blinatumomab
CAS:Blinatumomab (AMG-10,MT-103) is a CD19/CD3 bispecific B-cell and T-cell binding antibody that in acute lymphoblastic leukemia and non-Hodgkin's lymphoma.Forma y color:LiquidPironetin
CAS:Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.Fórmula:C19H32O4Pureza:98%Forma y color:SolidPeso molecular:324.45ALK inhibitor 2
CAS:ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.Fórmula:C23H28ClN7O3SPureza:99% - 99.77%Forma y color:SolidPeso molecular:518.03HS-27
CAS:HS-27 is a fluorescently-tethered inhibitor of Hsp90 with SNX-5422 tethered via a PEG linker to a fluorescein isothiocyanate or FITC.Fórmula:C52H60N6O12SPureza:97.09%Forma y color:SolidPeso molecular:993.13Ref: TM-T18018
1mg90,00€5mg215,00€10mg344,00€25mg612,00€50mg848,00€100mg1.159,00€1mL*10mM (DMSO)378,00€Chelerythrine chloride
CAS:Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect toFórmula:C21H18ClNO4Pureza:95% - 99.19%Forma y color:Yellow To Orange SolidPeso molecular:383.83Bosutinib hydrate
CAS:Bosutinib hydrate (SKI-606 hydrate) is a kinase inhibitor of BCR-ABL and Src tyrosine kinases for the study of leukemia.Fórmula:C26H31Cl2N5O4Pureza:99.87%Forma y color:SolidPeso molecular:548.46Synstatin (92-119)
CAS:Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 andFórmula:C133H207N35O46Pureza:98%Forma y color:SolidPeso molecular:3032.27GLPG0187
CAS:GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).Fórmula:C29H37N7O5SPureza:100% - 99.70%Forma y color:SolidPeso molecular:595.71PAK4-IN-3
PAK4-IN-3 (compound 27e) is a PAK4 inhibitor exhibiting an IC50 of 10 nM and demonstrates antiproliferative effects on A549 cells with an IC50 of 0.61μM.Pureza:98%Forma y color:Odour SolidAurothiomalate sodium
CAS:Sodium aurothiomalate (Miochrysin) inhibits PKC-ι, TrxR; used as an anti-rheumatic and has anti-tumor properties.Fórmula:C4H3AuNa2O4SPureza:99.66%Forma y color:SoildPeso molecular:390.07Capivasertib
CAS:Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity.Fórmula:C21H25ClN6O2Pureza:97.59% - 99.6%Forma y color:SolidPeso molecular:428.92Ref: TM-T1920
1mg40,00€2mg52,00€5mg70,00€10mg99,00€25mg168,00€50mg246,00€100mg378,00€200mg610,00€1mL*10mM (DMSO)89,00€Onalespib
CAS:Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.Fórmula:C24H31N3O3Pureza:98.05% - 99.82%Forma y color:SolidPeso molecular:409.52Norathyriol
CAS:Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.Fórmula:C13H8O6Pureza:98.90% - 98.93%Forma y color:SolidPeso molecular:260.2Ref: TM-TN1990
1mg149,00€5mg354,00€10mg528,00€25mg852,00€50mg1.159,00€100mg1.568,00€1mL*10mM (DMSO)522,00€α7β1 integrin modulator-1
CAS:α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1].Fórmula:C23H29N3O6SPureza:98%Forma y color:SolidPeso molecular:475.56AS2521780
CAS:AS2521780 is an inhibitor of PKCθ (IC50: 0.48 nM).Fórmula:C30H41N7OSPureza:98%Forma y color:SolidPeso molecular:547.76Dasatinib hydrochloride
CAS:Dasatinib hydrochloride is an oral Src/Bcr-Abl inhibitor with potent antitumor effects, Ki values of 16 pM (Src) and 30 pM (Bcr-Abl).Fórmula:C22H27Cl2N7O2SPureza:99.88% - 99.98%Forma y color:SolidPeso molecular:524.47Pep2m, myristoylated acetate
Pep2m, a myristoylated acetate, inhibits GluA2-NSF interaction, reducing AMPA receptor function and expression in neurons.Fórmula:C65H122N18O16SPureza:99.62%Forma y color:SolidPeso molecular:1443.96PKC 20-28,myristoylated
Myristoylated protein kinase C inhibitor 20-28 (PKC 20-28,myristoylated) is a cell-permeable inhibitor of protein kinase C, utilized in cancer research [1].Fórmula:C60H106N18O11Pureza:98%Forma y color:SolidPeso molecular:1255.6CMPD101
CAS:CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).Fórmula:C24H21F3N6OPureza:98.34% - 99.01%Forma y color:SolidPeso molecular:466.46TPPB
CAS:TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).Fórmula:C27H30F3N3O3Pureza:98.00%Forma y color:SolidPeso molecular:501.54DCP-LA
CAS:DCP-LA (FR236924), linoleic acid derivatives, selective and direct activation of PKCε.Fórmula:C20H36O2Pureza:98%Forma y color:SolidPeso molecular:308.5Abrilumab
CAS:Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.Forma y color:LiquidEgaptivon pegol
CAS:Egaptivon pegol (ARC1779) is an aptamer that inhibits the interaction of von Willebrand Factor (VWF) with platelet GPIb receptors, exhibiting anti-thromboticPureza:98%Forma y color:LiquidKinesore
CAS:Kinesore is a cell-permeable modulator that binds to the microtubule motor protein kinesin-1, thereby inhibiting the interaction between KLC2 and SKIP.Fórmula:C20H16Br2N4O4Pureza:97.24%Forma y color:SolidPeso molecular:536.17Ref: TM-T15663
2mg43,00€5mg66,00€10mg94,00€25mg159,00€50mg230,00€100mg346,00€200mg520,00€1mL*10mM (DMSO)74,00€Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)
Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin.Fórmula:C19H34N8O11Pureza:99.81%Forma y color:SolidPeso molecular:550.52(R)-Fangchinoline
CAS:(R)-Fangchinoline ((+)-Thalrugosine) is extracted from Stephania tetrandra S. Moore.Fórmula:C37H40N2O6Pureza:98% - 99.72%Forma y color:SolidPeso molecular:608.72Protein Kinase C (19-31)
CAS:Protein Kinase C (19-31), a PKC inhibitor derived from PKCa, has a serine at position 25 and tests PKC activity.Fórmula:C67H118N26O16Pureza:98%Forma y color:Lyophilized PowderPeso molecular:1543.82Mps1-IN-3
CAS:Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Fórmula:C26H31N7O4SPureza:99.25%Forma y color:SolidPeso molecular:537.63Ref: TM-T16130
2mg42,00€5mg64,00€10mg92,00€25mg170,00€50mg311,00€100mg449,00€200mg630,00€1mL*10mM (DMSO)74,00€Antitumor agent-86
CAS:Antitumor agent-86 targets MCF-7 cells with 2.62 µM IC50, induces apoptosis, and disrupts RAS/PI3K/Akt/JNK pathways.Fórmula:C29H31N5O2SPureza:98%Forma y color:SolidPeso molecular:513.65[Ala107]-MBP (104-118) acetate
[Ala107]-MBP (104-118) acetate ([Ala107]-MBP ) is synthetic peptide analog of bovine myelin basic protein (MBP).Fórmula:C59H108N20O21Pureza:99.23%Forma y color:SolidPeso molecular:1553.72Myosin V-IN-1
CAS:Myosin V-IN-1: potent, selective Myosin V inhibitor, Ki of 6 μM; hinders actin-activated ATPase by blocking ADP release.Fórmula:C29H26N6O3SPureza:97.31% - 97.31%Forma y color:SolidPeso molecular:538.62Ref: TM-T72060
1mg314,00€5mg663,00€10mg944,00€25mg1.396,00€50mg1.890,00€100mg2.547,00€1mL*10mM (DMSO)677,00€DPH
CAS:DPH is a potent cell permeable activator of c-Abl. It shows potent enzymatic and cellular activity in stimulating c-Abl activation.Fórmula:C18H13FN4O2Pureza:99.72%Forma y color:SolidPeso molecular:336.32BOS-172722
CAS:BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).Fórmula:C24H30N8OPureza:99.37%Forma y color:SolidPeso molecular:446.55AKT Kinase Inhibitor
CAS:AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity that selectively inhibits cell proliferation in a dose-dependent manner.Cost-effective and quality-assured.Fórmula:C16H19N7O3Pureza:98.53% - 99.86%Forma y color:SolidPeso molecular:357.37Ref: TM-T10276
1mg136,00€5mg329,00€10mg567,00€25mg887,00€50mg1.188,00€100mg1.605,00€1mL*10mM (DMSO)360,00€CCB02
CAS:CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity.Fórmula:C14H9N3OPureza:99.51%Forma y color:SolidPeso molecular:235.24Ref: TM-T10704
1mg115,00€5mg274,00€10mg432,00€25mg845,00€50mg1.293,00€100mg1.768,00€1mL*10mM (DMSO)303,00€p5 Ligand for Dnak and DnaJ acetate
p5 Ligand for Dnak and DnaJ acetate is a nonapeptide. It is a high-affinity ligand for DnaK (E. coli Hsp70) and DnaJ (E. coli Hsp40).Fórmula:C46H85N15O13SPureza:96.33%Forma y color:SolidPeso molecular:1088.32DOTA-cyclo(RGDfK)
CAS:DOTA-cyclo(RGDfK) is a and DOTA-like chelator peptide,the αvβ3 integrin receptor ,radionuclide coupled compounds RDCs cancer diagnostics and therapy.Fórmula:C43H67N13O14Forma y color:SoildPeso molecular:990.07Psychosine
CAS:Psychosine (Galactosylsphingosine) is a PKC inhibitor, and is highly cytotoxic, inducing cell death in a variety of cells.Fórmula:C24H47NO7Pureza:98%Forma y color:White PowderPeso molecular:461.63BI-1950
CAS:BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.Fórmula:C32H26Cl2FN7O3Pureza:98%Forma y color:SolidPeso molecular:646.5KU-177
CAS:KU-177 is an Aha1 inhibitor that disrupts the interaction between Hsp90 and Aha1, eliminating cell proliferation and PI resistance induced by elevated AHSA1.Fórmula:C27H23NO8Pureza:97.34% - 98.54%Forma y color:SolidPeso molecular:489.47KIF18A-IN-16
CAS:KIF18A-IN-16 (Compound 15) is a polycyclic KIF18A inhibitor. It is applicable in research related to tumors, including colon cancer, breast cancer, and lung cancer.Fórmula:C30H37N5O4SForma y color:SolidPeso molecular:563.71N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide
CAS:N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nMFórmula:C24H18ClN3OPureza:98.65%Forma y color:SoildPeso molecular:399.87Ref: TM-T60041
1mg115,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€200mg1.454,00€1mL*10mM (DMSO)279,00€GNF-7
CAS:GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.Fórmula:C28H24F3N7O2Pureza:97.05% - 99.47%Forma y color:SolidPeso molecular:547.53(-)-Indolactam V
CAS:(-)-Indolactam V: PKC activator, antitumor, Ki 3.36 nM/1.03 μM for η/γ-CRD2, Kd 5.5-213 nM for C1 domains.Fórmula:C17H23N3O2Pureza:98%Forma y color:SolidPeso molecular:301.38ZINC194100678
CAS:ZINC194100678 is an effective PAK1 inhibitor with IC50 of 8.37μM.Fórmula:C10H13N5OPureza:98.3%Forma y color:SolidPeso molecular:219.24Tau-aggregation and neuroinflammation-IN-1
CAS:Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.Fórmula:C25H20N2O7Pureza:100%Forma y color:SolidPeso molecular:460.44VER49009
CAS:VER49009 (CCT0129397) is an effective HSP90 inhibitor(IC50 =25 nM, Kd=78 nM).Fórmula:C19H18ClN3O4Pureza:100% - 99.17%Forma y color:SolidPeso molecular:387.82Ref: TM-T2268
1mg60,00€2mg85,00€5mg111,00€10mg167,00€25mg283,00€50mg472,00€100mg643,00€1mL*10mM (DMSO)96,00€HSDVHK-NH2 acetate
P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).Fórmula:C32H52N12O11Pureza:99.50%Forma y color:SolidPeso molecular:780.39Gantofiban
CAS:Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.Fórmula:C21H29N5O6Pureza:99.21%Forma y color:SolidPeso molecular:447.48FAK inhibitor 7
CAS:FAK inhibitor7, a potent FAK inhibitor, demonstrates an IC50 of 3.58 nM. This compound effectively inhibits downstream signaling cascades of FAK (such as Src and AKT), which leads to cell cycle arrest at the G0/G1 phase and induces cytotoxic autophagy in ovarian cancer cells. Additionally, FAK inhibitor7 has been shown to suppress tumor metastasis and growth in ovarian cancer mouse models.Fórmula:C32H37N7O3Forma y color:SolidPeso molecular:567.68ALK-IN-29
ALK-IN-29 (compound 4c) exhibits inhibitory effects on tyrosine protein kinases such as ALK, CDK2/CyclinE1, and FAK, with the strongest inhibition observed against ALK kinase, displaying a 40.63% inhibition rate at a concentration of 10 μM. ALK-IN-29 is applicable in cancer research.Fórmula:C29H32FN3OForma y color:SolidPeso molecular:457.58MPT0B014
CAS:MPT0B014 is a potent tubulin polymerization inhibitor. MPT0B014 can induce cancer cell apoptosis.Fórmula:C19H17NO4Pureza:99.56%Forma y color:SolidPeso molecular:323.34PF-04691502
CAS:PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.Fórmula:C22H27N5O4Pureza:96.27% - ≥95%Forma y color:SolidPeso molecular:425.48KU-32
CAS:KU-32 is a novel and novobiocin-based Hsp90 inhibitor. It can protect against neuronal cell death.Fórmula:C20H25NO8Pureza:98%Forma y color:SolidPeso molecular:407.41iRGD peptide
CAS:iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.Fórmula:C35H57N13O14S2Pureza:98.77%Forma y color:SolidPeso molecular:948.04S-methyl DM1
CAS:S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.Fórmula:C36H50ClN3O10SPureza:98%Forma y color:SolidPeso molecular:752.31HSP90-IN-22
CAS:HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor exhibiting antiproliferative activity, with IC50 values of 3.65 μM in MCF7 breast cancer cells and 2.71 μM inFórmula:C25H30N4O3Pureza:98%Forma y color:SolidPeso molecular:434.53
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