Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Productos de "Señalización citoesquelética"
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Cenisertib
CAS:Cenisertib is A potent ATP-competitive multi-kinase inhibitor, showing inhibitory effects on the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5, FLT3, as wellFórmula:C24H30FN7OForma y color:SolidPeso molecular:451.54XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Fórmula:C22H31N9OPureza:99.07%Forma y color:SolidPeso molecular:437.54Ref: TM-T17267
1mg56,00€2mg78,00€5mg99,00€10mg149,00€25mg258,00€50mg393,00€100mg582,00€1mL*10mM (DMSO)110,00€Bisindolylmaleimide VIII acetate
CAS:Bisindolylmaleimide VIII acetate is a selective PKC inhibitor with an IC50 of 158 nM in rat brain and varying IC50s for different PKC isoforms.Fórmula:C26H26N4O4Pureza:99.27%Forma y color:SolidPeso molecular:458.51PKC-ε translocation inhibitor peptide
PKC-ε Translocation Inhibitor Peptide is a selective modulator that controls the FcγR-mediated internalization rate of opsonized beads without affecting FcαRPureza:98%Forma y color:Odour SolidArg-Gly-Asp TFA (99896-85-2(free base))
Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.Fórmula:C14H23F3N6O8Pureza:99.2% - ≥98%Forma y color:SolidPeso molecular:460.36STX-100
PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.Pureza:95% - 95%Forma y color:Odour LiquidEMD534085
CAS:EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).Fórmula:C25H31F3N4O2Pureza:98%Forma y color:SolidPeso molecular:476.53Nilotinib monohydrochloride monohydrate
CAS:Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation tyrosineFórmula:C28H22F3N7O·HCl·H2OPureza:99.93%Forma y color:SolidPeso molecular:583.99Anti-Mouse IL-1a Antibody (ALF-161)
Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.Pureza:98%Forma y color:Odour SolidDanicamtiv
CAS:Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.Fórmula:C16H20F3N5O4SPureza:99.38%Forma y color:SolidPeso molecular:435.42Ref: TM-T15050
1mg136,00€5mg274,00€10mg454,00€25mg750,00€50mg1.026,00€100mg1.406,00€1mL*10mM (DMSO)303,00€LY 379196
LY 379196, a potent PKC-β inhibitor (IC 50: 50 nM for PKC βI and 30 nM for PKC βII), effectively suppresses the proliferation of bovine retinal microvascular endothelial cells (BREC) induced by VEGF, IGF-1, and bFGF. This compound serves as an antiproliferative agent for proliferative retinopathy.Fórmula:C30H34N4O5SForma y color:SolidPeso molecular:562.68XL888
CAS:XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.Fórmula:C29H37N5O3Pureza:98.1%Forma y color:SolidPeso molecular:503.64Loureirin A
CAS:Loureirin A inhibits platelet aggregation and PI3K/Akt signaling, promotes hair follicle repair, and has anti-fibrotic and anti-angiogenic properties.Fórmula:C17H18O4Pureza:99.83% - 99.84%Forma y color:SolidPeso molecular:286.32Ref: TM-T5S0896
1mg74,00€5mg133,00€10mg188,00€25mg329,00€50mg490,00€100mg697,00€200mg938,00€1mL*10mM (DMSO)207,00€Mitoxantrone
CAS:Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.Fórmula:C22H28N4O6Pureza:97.97% - 98.74%Forma y color:Blue PowderPeso molecular:444.48CID-663143
CAS:CID-663143 inhibits cancer cell growth and shows microtubule-binding activity.Fórmula:C19H18N4O2SPureza:99.56% - 99.68%Forma y color:SolidPeso molecular:366.44Ref: TM-T23889
1mg77,00€5mg158,00€10mg225,00€25mg338,00€50mg475,00€100mg638,00€200mg845,00€1mL*10mM (DMSO)164,00€Soblidotin
CAS:Soblidotin (TZT-1027) (Auristatin PE) is an inhibitor of tubulin polymerization. It is also a novel synthetic Dolastatin 10 derivative.Fórmula:C39H67N5O6Pureza:97.48%Forma y color:SolidPeso molecular:701.98DCPLA-ME
CAS:DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerativeFórmula:C21H38O2Pureza:98.16%Forma y color:SolidPeso molecular:322.53Ref: TM-T10980
1mg65,00€5mg133,00€10mg180,00€25mg369,00€50mg605,00€100mg815,00€200mg1.111,00€1mL*10mM (DMSO)145,00€MT189
CAS:MT189 (Antiproliferative agent-14) inhibits tubulin polymerization (IC50 3.41 μM), arrests G2/M cell cycle, and is highly antiproliferative.Fórmula:C21H18FN3O2Pureza:98.67%Forma y color:SoildPeso molecular:363.38G-5555 hydrochloride (1648863-90-4 free base)
G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM.Fórmula:C25H26Cl2N6O3Pureza:98%Forma y color:SolidPeso molecular:529.42TAS0612
CAS:TAS0612, a novel oral inhibitor of RSK, AKT, and S6K, exhibits broad-spectrum antitumor activity by impeding cell growth [1].Fórmula:C27H34F3N9O2Pureza:98%Forma y color:SolidPeso molecular:573.61Recilisib
CAS:Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.Fórmula:C16H13ClO4SPureza:98.85% - 98.96%Forma y color:SolidPeso molecular:336.79Ref: TM-T13862
1mg46,00€2mg59,00€5mg87,00€10mg119,00€25mg187,00€50mg354,00€100mg528,00€500mg1.159,00€1mL*10mM (DMSO)105,00€LP-261
CAS:LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.Fórmula:C22H19N3O4SPureza:99.76%Forma y color:SolidPeso molecular:421.47Ref: TM-T9595
1mg38,00€2mg49,00€5mg79,00€10mg119,00€25mg187,00€50mg354,00€100mg528,00€1mL*10mM (DMSO)87,00€Sabizabulin
CAS:Sabizabulin (ABI-231) is a potent, orally bioavailable α- and β-tubulin inhibitor.Cost-effective and quality-assured.Fórmula:C21H19N3O4Pureza:98.04% - 99.76%Forma y color:SolidPeso molecular:377.39Ref: TM-T17228
1mg145,00€2mg207,00€5mg354,00€10mg547,00€25mg880,00€50mg1.198,00€100mg1.596,00€500mg3.220,00€KOdiA-PC
CAS:KOdiA-PC is a truncated oxidized phospholipid and a CD36-targeting ligand found on oxLDL. It inhibits activation of TLR4 signaling components.Fórmula:C32H58NO11PForma y color:SolidPeso molecular:663.78PKC β pseudosubstrate acetate
PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.Pureza:95.01%Forma y color:SoildMps1-IN-2
CAS:Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.Fórmula:C26H36N6O3Pureza:96.24% - 99.75%Forma y color:SolidPeso molecular:480.6Sotrastaurin
CAS:Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).Fórmula:C25H22N6O2Pureza:98% - 99.70%Forma y color:SolidPeso molecular:438.48Ref: TM-T6278
1mg49,00€5mg96,00€10mg166,00€25mg313,00€50mg553,00€100mg790,00€500mg1.578,00€1mL*10mM (DMSO)115,00€K-80003
CAS:K-80003(TX-803) is a potent retinol-like X-receptor-alpha regulator that inhibits TRxrα-dependent Akt activation and tumor cell growth.Fórmula:C22H21FO2Pureza:99.76%Forma y color:SolidPeso molecular:336.4Ref: TM-T11734
1mg49,00€5mg104,00€10mg166,00€25mg283,00€50mg430,00€100mg633,00€500mg1.349,00€1mL*10mM (DMSO)115,00€Bexotegrast
CAS:Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).Fórmula:C27H36N6O3Pureza:99.53%Forma y color:SolidPeso molecular:492.61Rotigaptide TFA(355151-12-1 free base)
Rotigaptide TFA is a Cx43 modulator & AAP that maintains gap junctions & cell communication under stress.Fórmula:C30H40F3N7O11Pureza:99.21%Forma y color:SolidPeso molecular:731.67PROTAC Hsp90α degrader 1
Compound X10g (PROTAC Hsp90α degrader 1) is a selective agent targeting Hsp90α for degradation and is utilized in breast cancer research.Fórmula:C43H50N6O7Pureza:98%Forma y color:SolidPeso molecular:762.89PF-562271 besylate
CAS:PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.Fórmula:C21H20F3N7O3S·C6H6O3SPureza:97.65% - 99.01%Forma y color:SolidPeso molecular:665.66Ref: TM-T6177
1mg38,00€5mg79,00€10mg88,00€25mg145,00€50mg210,00€100mg313,00€200mg452,00€1mL*10mM (DMSO)95,00€Efalizumab
CAS:Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.Pureza:SDS-PAGE:95% SEC-HPLC:98.77%Forma y color:LiquidPeso molecular:146.14 kDaAntiangiogenic agent 4
Compound 3b, an antiangiogenic agent, inhibits Akt phosphorylation in both HFF and HUVEC cells and is utilized in cancer research [1].Fórmula:C21H24N4O3Pureza:98%Forma y color:SolidPeso molecular:380.44NAP1051
CAS:NAP1051, a biomimetic analog of Lipoxin A4, serves an anti-tumor role by targeting the inflammatory tumor microenvironment. It inhibits the chemotaxis of neutrophils to fMLP and stimulates macrophage efferocytosis by activating AKT. NAP1051 is utilized in research on colorectal cancer.Fórmula:C23H34O5Forma y color:SolidPeso molecular:390.51YM-53601
CAS:YM-53601 is an SQS inhibitor that inhibits adipogenic biosynthesis and lipid secretion in rodents.YM-53601 is a cholesterol-lowering agent that inhibits FDFT1.Fórmula:C21H22ClFN2OPureza:99.65%Forma y color:SolidPeso molecular:372.86FAK-IN-10
CAS:FAK-IN-10 is an inhibitor of FAK (IC50:76.3 μM).FAK-IN-10 z MCF-7 and A431 cell lines showed antitumor activity with IC50 of 4.23 and 0.78 μM, respectively.Fórmula:C15H10BrN3O2SPureza:99.78%Forma y color:SoildPeso molecular:376.23FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro
CAS:FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro, also known as FITC-linked GRGDSP, is a fluorescent peptide with integrin inhibitory properties.Fórmula:C49H59N11O16SPureza:98%Forma y color:SolidPeso molecular:1090.12Vodobatinib
CAS:Vodobatinib (K-0706) is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.Fórmula:C27H20ClN3O2Pureza:99.06% - 99.55%Forma y color:SolidPeso molecular:453.92Ref: TM-T8882
1mg37,00€5mg79,00€10mg116,00€25mg212,00€50mg340,00€100mg528,00€500mg1.275,00€1mL*10mM (DMSO)87,00€Obtustatin triacetate
Obtustatin triacetate, a 41-residue non-RGD disintegrin isolated from the venom of Vipera lebetina obtusa, serves as a potent and selective inhibitor of theFórmula:C184H284N52O57S8·3C2H4O2Pureza:99.51%Forma y color:SolidPeso molecular:4573.21KW-2478
CAS:KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM.Fórmula:C30H42N2O9Pureza:98.68% - 99.52%Forma y color:SolidPeso molecular:574.66Ref: TM-T6558
1mg56,00€2mg81,00€5mg119,00€10mg187,00€25mg316,00€50mg472,00€100mg662,00€1mL*10mM (DMSO)205,00€Mavacamten
CAS:Mavacamten (MYK-461) is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)Fórmula:C15H19N3O2Pureza:99.53% - 99.98%Forma y color:SolidPeso molecular:273.33[Ala113]-MBP (104-118) acetate
[Ala113]MBP(104-118) acetate is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 28-62 μM.Fórmula:C69H108N20O21Pureza:97.72%Forma y color:SolidPeso molecular:1553.74Gypsogenin
CAS:Gypsogenin (639-14-5) is a naturally occurring biochemical that shows anti-ABL1 kinase and anti-chronic Myelogenous Leukemia activities.Fórmula:C30H46O4Pureza:99.73%Forma y color:SolidPeso molecular:470.68Ref: TM-T25476
1mg134,00€5mg315,00€10mg469,00€25mg748,00€50mg1.064,00€100mg1.415,00€1mL*10mM (DMSO)349,00€Tubulin inhibitor 7
CAS:Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (Fórmula:C21H14N2O4Pureza:98%Forma y color:SolidPeso molecular:358.35ICAM-1-IN-1
CAS:ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.Fórmula:C15H11BrN2O2SPureza:99.34%Forma y color:SolidPeso molecular:363.23Ref: TM-T13147
1mg185,00€5mg393,00€10mg587,00€25mg935,00€50mg1.264,00€100mg1.700,00€500mg3.410,00€1mL*10mM (DMSO)432,00€Benproperine phosphate
CAS:Benproperine phosphate (Pirexyl phosphate) is a cough suppressant.Fórmula:C21H30NO5PPureza:99.84%Forma y color:PowderPeso molecular:407.44Bimosiamose disodium
CAS:Bimosiamose disodium (TBC-1269Z), a pan-selectin inhibitor, has IC50s: E-selectin 88 μM, P-selectin 20 μM, L-selectin 86 μM; anti-inflammatory.Fórmula:C46H52Na2O16Pureza:98%Forma y color:SolidPeso molecular:906.88IPA-3
CAS:IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6).Fórmula:C20H14O2S2Pureza:96.7%Forma y color:SolidPeso molecular:350.45Peptide5 TFA
Peptide5 TFA, a connexin 43 mimetic peptide, mitigates swelling, astrogliosis, and neuronal cell death in animal models of spinal cord injury.Fórmula:C62H99F3N16O22SPureza:98%Forma y color:SolidPeso molecular:1509.6α2β1 Integrin Ligand Peptide acetate
α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor.Fórmula:C16H26N4O11Pureza:98.46%Forma y color:SolidPeso molecular:450.4Larixol
CAS:Larixol acts as both an fMLP inhibitor and a modulator of various signaling pathways by inhibiting Src kinase, ERK1/2, p38, and AKT phosphorylation critical forFórmula:C20H34O2Pureza:98%Forma y color:SolidPeso molecular:306.48BGG463
CAS:BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with an IC50 of 0.25 μM, 0.09 μM and 0.590 μM, respectively.Fórmula:C30H29F3N6O3Pureza:100% - 95.05%Forma y color:SolidPeso molecular:578.58Ref: TM-T4618
1mg62,00€2mg87,00€5mg119,00€10mg188,00€25mg350,00€50mg505,00€100mg730,00€1mL*10mM (DMSO)154,00€Protein Kinase C (19-31) (TFA)(121545-65-1,free)
Protein Kinase C (19-31) TFA is a serine-modified PKCa-derived inhibitor for testing PKC activity.Fórmula:C69H119F3N26O18Pureza:98%Forma y color:SolidPeso molecular:1657.842',4'-DIHYDROXYCHALCONE
CAS:2',4'-DIHYDROXYCHALCONE (2',4'-DHC) as a compound with Hsp90 inhibitory and antifungal effectsFórmula:C15H12O3Pureza:98.95%Forma y color:SolidPeso molecular:240.25Ref: TM-T8829
2mg42,00€5mg62,00€10mg87,00€25mg154,00€50mg235,00€100mg354,00€200mg520,00€1mL*10mM (DMSO)65,00€Triclabendazole
CAS:Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease.Fórmula:C14H9Cl3N2OSPureza:99.11%Forma y color:White To Brown Crystalline PowderPeso molecular:359.66Tubulin inhibitor 24
CAS:Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.Fórmula:C22H21N3O3Pureza:99.89%Forma y color:SolidPeso molecular:375.42Rocaglamide
CAS:Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.Fórmula:C29H31NO7Pureza:95.32% - 98.46%Forma y color:SolidPeso molecular:505.56mP6
CAS:mP6 (Myr-FEEERA-OH), a myristoylated peptide, selectively inhibits Gα 13's interaction with integrin β 3 while preserving talin-dependent integrin function.Fórmula:C47H75N9O14Pureza:98%Forma y color:SolidPeso molecular:990.15HG-7-86-01
CAS:HG-7-86-01 is a selective type II tyrosine kinase inhibitor with antiproliferative activity against mutant T315I- Bcr-Abl for chronic myeloid leukemia (CML).Fórmula:C28H21F3N6O2SPureza:99.07%Forma y color:SolidPeso molecular:562.57Bisindolylmaleimide V
CAS:Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor.Fórmula:C21H15N3O2Pureza:90%Forma y color:Red SolidPeso molecular:341.36Verubulin
CAS:Verubulin (MPC 6827) is a microtubule blocking agent with cytotoxic and potentially anticancer activity that disrupts newly formed blood vessels in xenografts.Fórmula:C17H17N3OPureza:99.98%Forma y color:SolidPeso molecular:279.34UMK57
CAS:UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,Fórmula:C17H17N3SPureza:99.81%Forma y color:SolidPeso molecular:295.4Thiabendazole
CAS:Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property.Fórmula:C10H7N3SPureza:99.14%Forma y color:Light Yellow PowderPeso molecular:201.25PKCβII Peptide Inhibitor I
CAS:PKCβII Peptide Inhibitor I, a specific PKCβII inhibitor, exhibits cardioprotective properties in a rat cardiac ischemia/reperfusion injury model and mitigatesFórmula:C61H94N12O19Pureza:98%Forma y color:SolidPeso molecular:1299.47EL-102
CAS:EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer.Fórmula:C19H16N2O3S2Pureza:99.34%Forma y color:SolidPeso molecular:384.47Ref: TM-T15205
1mg87,00€5mg216,00€10mg349,00€25mg545,00€50mg740,00€100mg1.103,00€1mL*10mM (DMSO)183,00€AG957
CAS:Tyrphostin AG957, a tyrosine kinase inhibitor with anti-BCR/ABL tyrosine kinase activity restores beta1 integrin-mediated adhesion and inhibitory signaling inFórmula:C15H15NO4Pureza:98.82%Forma y color:SolidPeso molecular:273.28Ref: TM-T21785
1mg89,00€5mg212,00€10mg315,00€25mg527,00€50mg750,00€100mg1.017,00€1mL*10mM (DMSO)265,00€Adaphostin
CAS:Adaphostin (NSC-680410) is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.Fórmula:C24H27NO4Pureza:97.31%Forma y color:SolidPeso molecular:393.48Vaccarin
CAS:Vaccarin, a key flavonoid glycoside in Vaccariae semen, undergoes methylation, hydroxylation, glycosylation, and deglycosylation.Fórmula:C32H38O19Pureza:99.16% - 99.97%Forma y color:SolidPeso molecular:726.63GSK-923295
CAS:GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).Fórmula:C32H38ClN5O4Pureza:96.22% - 98.02%Forma y color:SolidPeso molecular:592.13Ref: TM-T2039
1mg49,00€2mg70,00€5mg97,00€10mg168,00€25mg331,00€50mg510,00€100mg737,00€1mL*10mM (DMSO)136,00€Mitoxantrone dihydrochloride
CAS:Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.Fórmula:C22H30Cl2N4O6Pureza:100% - 99.85%Forma y color:Blue-Black Solid From Water Ethanol SolidPeso molecular:517.4Feretoside
CAS:Feretoside is a natural product extracted from the barks of E. ulmoides. Feretoside shows inducible activity on the heat shock factor 1 (HSF1).Fórmula:C17H24O11Pureza:99.15%Forma y color:SolidPeso molecular:404.37Ref: TM-TQ0280
1mg85,00€5mg180,00€10mg274,00€25mg465,00€50mg663,00€100mg919,00€500mg1.833,00€1mL*10mM (DMSO)298,00€Ombrabulin
CAS:Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells.Fórmula:C21H26N2O6Pureza:98%Forma y color:SolidPeso molecular:402.44GW406108X
CAS:GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.Fórmula:C20H11Cl2NO4Pureza:98%Forma y color:SolidPeso molecular:400.2117-AEP-GA
CAS:17-AEP-GA is an HSP90 antagonist and a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion.Fórmula:C34H50N4O8Pureza:97.77% - 99.56%Forma y color:SolidPeso molecular:642.78Tirofiban hydrochloride monohydrate
CAS:Tirofiban(MK383) hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.Fórmula:C22H39ClN2O6SPureza:95.83% - 99.94%Forma y color:White SolidPeso molecular:495.07Desmethylglycitein
CAS:Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which hasFórmula:C15H10O5Pureza:97.93%Forma y color:SolidPeso molecular:270.24Ref: TM-TN1299
1mg178,00€5mg540,00€10mg715,00€25mg1.103,00€50mg1.491,00€100mg2.005,00€500mg4.010,00€1mL*10mM (DMSO)442,00€PF-2771
CAS:PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.Fórmula:C29H36ClN5O4Pureza:98%Forma y color:SolidPeso molecular:554.08PKCβ inhibitor 1
CAS:PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2,Fórmula:C24H21N5O2Pureza:99.33%Forma y color:SolidPeso molecular:411.46Ref: TM-T8376
1mg154,00€5mg424,00€10mg605,00€25mg920,00€50mg1.216,00€100mg1.673,00€200mg2.252,00€500µg93,00€1mL*10mM (DMSO)401,00€Ingenol
CAS:Ingenol mebutate treats actinic keratosis, has anticancer properties, and may reactivate latent HIV.Fórmula:C20H28O5Pureza:99.78% - 99.87%Forma y color:SolidPeso molecular:348.43Ref: TM-T5S2017
1mg52,00€5mg95,00€10mg127,00€25mg246,00€50mg467,00€100mg640,00€500mg1.359,00€1mL*10mM (DMSO)96,00€PF04929113
CAS:PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.Fórmula:C25H30F3N5O4Pureza:99.06%Forma y color:SolidPeso molecular:521.53Ref: TM-T6341
1mg39,00€2mg49,00€5mg84,00€10mg119,00€25mg187,00€50mg354,00€100mg527,00€1mL*10mM (DMSO)96,00€OXA-11
CAS:OXA-11 (FAK-IN-16) is a FAK inhibitor with anti-tumor activity, useful for cancer research.Fórmula:C37H49F3N7O5PPureza:98.70% - 99.20%Forma y color:SolidPeso molecular:759.8cSRC/BCR-ABL1-IN-1
cSRC/BCR-ABL1-IN-1 (compound 16a) is a dual-target inhibitor of the cSRC/BCR-ABL1 kinases.Fórmula:C24H27ClN6O4Forma y color:SolidPeso molecular:498.96HSP90-IN-19
CAS:HSP90-IN-19: potent Hsp90 inhibitor, IC50 = 0.27 μM, used in research on viral diseases, neurodegeneration, inflammation.Fórmula:C29H38O7Pureza:98%Forma y color:SolidPeso molecular:498.61ATM-3507
CAS:ATM-3507 is an inhibitor of tropomyosin. In human melanoma cell lines, the IC50s are from 3.83-6.84 μM.Fórmula:C37H46FN5O2Pureza:96.36% - 99.10%Forma y color:SolidPeso molecular:611.79Asciminib
CAS:Asciminib (ABL001) (ABL001) is a potent and selective Bcr-Abl inhibitor (Kd: 0.5-0.8nM).Fórmula:C20H18ClF2N5O3Pureza:97.93% - 99.45%Forma y color:SolidPeso molecular:449.84Ref: TM-T5177
1mg63,00€2mg92,00€5mg127,00€10mg187,00€25mg305,00€50mg427,00€100mg630,00€500mg1.320,00€1mL*10mM (DMSO)139,00€Natalizumab
CAS:Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.Pureza:98.00%Forma y color:LiquidPeso molecular:N/AHSP90-IN-32
CAS:HSP90-IN-32, a carboxy-terminus inhibitor of Hsp90C, exhibits antiproliferative activity in various cell lines including SKMel173, SKMel103, SKMel19, and A375, with IC50 values of 1.01 μM, 0.782 μM, 0.607 μM, and 1.413 μM, respectively. This compound holds potential for research in anticancer agents.Fórmula:C33H40N2O4Forma y color:SolidPeso molecular:528.68CW-069
CAS:CW-069 (IC50=75 μM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.Fórmula:C23H21IN2O3Pureza:97.52% - 98.59%Forma y color:SolidPeso molecular:500.33Ref: TM-T6209
1mg43,00€5mg90,00€10mg125,00€25mg216,00€50mg306,00€100mg432,00€500mg938,00€1mL*10mM (DMSO)89,00€DM4
CAS:DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.Fórmula:C38H54ClN3O10SPureza:98.15%Forma y color:SolidPeso molecular:780.37NQTrp
CAS:NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.Fórmula:C21H16N2O4Pureza:98%Forma y color:SolidPeso molecular:360.36N-Phenylbenzylamine
CAS:A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerizationFórmula:C13H13NPureza:99.93%Forma y color:Colorless To Pale Yellow Crystalline PowderPeso molecular:183.25Curvulin
CAS:Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.Fórmula:C12H14O5Pureza:98.97%Forma y color:SolidPeso molecular:238.24Ref: TM-T36850
1mg145,00€5mg319,00€10mg472,00€25mg753,00€50mg1.074,00€100mg1.444,00€1mL*10mM (DMSO)284,00€Hu7691 free base
CAS:Hu7691 free base is an Akt inhibitor that inhibits Akt1, Akt2 and Akt3 and induces differentiation of neuroblastoma cells.Fórmula:C22H21F3N4OPureza:98.89%Forma y color:SolidPeso molecular:414.423H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.Fórmula:C23H38N10O10Pureza:100%Forma y color:SolidPeso molecular:614.61Phenamacril
CAS:Phenamacril (JS39919) is acyanoacrylate fungicide, has powerful inhibition against Fusarium species, especially to Fusarium graminearum.Fórmula:C12H12N2O2Pureza:99.37%Forma y color:SolidPeso molecular:216.24Ref: TM-T24214
1mg145,00€5mg319,00€10mg472,00€25mg753,00€50mg1.074,00€100mg1.444,00€500mg2.822,00€1mL*10mM (DMSO)274,00€α-Linolenic acid
CAS:α-Linolenic Acid (ALA) is an essential fatty acid. α-Linolenic acid improves memory, inhibits thrombosis, and lowers blood lipids. Cost-effective and quality-assured.Fórmula:C18H30O2Pureza:98.19% - 99.81%Forma y color:Physical Description Clear Colorless Liquid (Ntp 1992)Peso molecular:278.43Cyclo(RGDfC) TFA
Zelminemab (AMG-301) is a humanized monoclonal antibody targeting ADCYAP1R1 for use in neurological disorders.Fórmula:C26H35F3N8O9SPureza:98.59%Forma y color:SolidPeso molecular:692.67ɛPKC(85-92),Myristoylated
CAS:PKC(85-92),Myristoylated is a myristic acid-conjugated, cell-permeable peptide activator of PKC that has been shown to increase nitric oxide (NO) release inFórmula:C53H80N10O15Pureza:98%Forma y color:SolidPeso molecular:1097.26cRGDfK-thioacetyl ester
CAS:cRGDfK-thioacetyl ester, a bioactive polypeptide, exhibits selective affinity for integrins and can modify near-infrared (NIR) fluorescent probes for targetedFórmula:C31H45N9O9SPureza:98%Forma y color:SolidPeso molecular:719.81
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