Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Productos de "Señalización citoesquelética"
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Aβ-IN-1 TFA
Aβ-IN-1 TFA inhibits and reverses different types of protein aggregation.Fórmula:C37H50F3NO2Pureza:100%Forma y color:SoildPeso molecular:597.79SNX2112
CAS:SNX2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM.Fórmula:C23H27F3N4O3Pureza:98.9% - 99.46%Forma y color:SolidPeso molecular:464.48Ref: TM-T6305
1mg40,00€5mg85,00€10mg127,00€25mg220,00€50mg334,00€100mg477,00€200mg662,00€1mL*10mM (DMSO)87,00€CCT251236
CAS:CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen.Fórmula:C32H32N4O5Pureza:98.82% - 99.89%Forma y color:SolidPeso molecular:552.62Ref: TM-T14905
1mg39,00€5mg116,00€10mg221,00€25mg457,00€50mg733,00€100mg1.111,00€200mg1.501,00€1mL*10mM (DMSO)144,00€Protein kinase inhibitor H-7 dihydrochloride
CAS:Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.Fórmula:C14H19Cl2N3O2SPureza:99.54%Forma y color:White Crystalline SolidPeso molecular:364.29Entasobulin
CAS:Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.Fórmula:C26H18ClN3O2Pureza:98.40%Forma y color:SolidPeso molecular:439.89Bisindolylmaleimide IV
CAS:Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)Fórmula:C20H13N3O2Pureza:98.83%Forma y color:Dark Red SolidPeso molecular:327.34Cyclo(-RGDfK)
CAS:Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.Fórmula:C27H41N9O7Pureza:100% - 99.83%Forma y color:SolidPeso molecular:603.67Arg-Gly-Asp-Ser
CAS:Arg-Gly-Asp-Ser (RGDS peptide) is a conserved tetrapeptide sequence found in fibronectin, and the von Willebrand factor.Fórmula:C15H27N7O8Pureza:98.29%Forma y color:SolidPeso molecular:433.421,2-Dimyristoyl-sn-glycerol
CAS:1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is able to increase AChE activity by 35-40% at concentrations of 25 micrograms/ml in the parasite S. mansoni..Fórmula:C31H60O5Pureza:99.49%Forma y color:White Powder With LumpsPeso molecular:512.81PD180970
CAS:PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit.Fórmula:C21H15Cl2FN4OPureza:98.47%Forma y color:SolidPeso molecular:429.27Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)
CAS:Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide and a synthetic α5β1 integrin ligand.Fórmula:C22H35N9O9Pureza:98%Forma y color:SolidPeso molecular:569.57PF-06651481-00
CAS:PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.Fórmula:C26H29Cl2N5O3Pureza:97.57%Forma y color:SolidPeso molecular:530.45SR31527
CAS:SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.Fórmula:C15H14ClN3OSPureza:98%Forma y color:SolidPeso molecular:319.81PLN-1474
CAS:PLN-1474 is a potent αVβ1 inhibitor with IC50 < 50 nM.Fórmula:C24H37N3O4Pureza:99.25%Forma y color:SoildPeso molecular:431.57Ref: TM-T60101
1mg52,00€5mg111,00€10mg180,00€25mg305,00€50mg439,00€100mg612,00€1mL*10mM (DMSO)124,00€Cercosporin
CAS:Cercosporin, produced by the plant pathogen Cercospora kikuchii and the elsinochromes, is a potent photosensitizer with a short activation wavelength. Cercosporin contains perylene quinone structural features essential for PKC activity (IC50: 0.6-1.3 μM).Fórmula:C29H26O10Pureza:98%Forma y color:SolidPeso molecular:534.51N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Fórmula:C28H29N7OPureza:98.60%Forma y color:Off-White To Pale-Yellow SolidPeso molecular:479.58Ref: TM-T11641
1mg92,00€5mg170,00€10mg319,00€25mg540,00€50mg777,00€100mg1.074,00€1mL*10mM (DMSO)178,00€Geldanamycin
CAS:Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.Fórmula:C29H40N2O9Pureza:98.83% - 99.27%Forma y color:Yellow To Orange PowderPeso molecular:560.64MAP4343
CAS:Map4343, a 3-methyl ether pregnenolone derivative, binds MAP2, boosts tubulin polymerization, spurs neurite growth, and guards neurons.Fórmula:C22H34O2Pureza:99.32%Forma y color:SolidPeso molecular:330.5E7820
CAS:E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).Fórmula:C17H12N4O2SPureza:98.31% - 99.11%Forma y color:SolidPeso molecular:336.37Ref: TM-T4435
1mg35,00€2mg52,00€5mg69,00€10mg88,00€25mg144,00€50mg210,00€100mg339,00€200mg502,00€1mL*10mM (DMSO)85,00€Iso-H7 dihydrochloride
CAS:Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.Fórmula:C14H19Cl2N3O2SPureza:99.64%Forma y color:White Crystalline SolidPeso molecular:364.29Ref: TM-T7501
2mg40,00€5mg52,00€10mg90,00€25mg138,00€50mg197,00€100mg293,00€200mg408,00€1mL*10mM (DMSO)66,00€FAK-IN-21
CAS:FAK-IN-21 (compound 9) is a FAK inhibitor with an IC50 value of 37.52 nM. It inhibits cell growth and the phosphorylation of FAK, making it useful for research into diffuse gastric cancer.Fórmula:C22H22F2N8O3SForma y color:SolidPeso molecular:516.52KIF18A-IN-2
CAS:KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.Fórmula:C25H34N4O5S2Pureza:99.05%Forma y color:SolidPeso molecular:534.69Ref: TM-T60026
1mg74,00€5mg172,00€10mg245,00€25mg383,00€50mg507,00€100mg672,00€200mg910,00€1mL*10mM (DMSO)202,00€HSP70-IN-1
CAS:HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM).Fórmula:C24H28N6O2SPureza:100%Forma y color:SolidPeso molecular:464.58Ref: TM-T3487
1mg96,00€5mg227,00€10mg354,00€25mg620,00€50mg847,00€100mg1.169,00€1mL*10mM (DMSO)230,00€ABT-751
CAS:ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.Fórmula:C18H17N3O4SPureza:98.84% - 99.50%Forma y color:SolidPeso molecular:371.41AKE-72
CAS:AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing natural BCR-ABL or its T315I mutant.Fórmula:C30H29F3N6OPureza:98.3%Forma y color:SoildPeso molecular:546.59Radotinib
CAS:Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notablyFórmula:C27H21F3N8OPureza:99.13% - 99.97%Forma y color:SolidPeso molecular:530.5Col003
CAS:Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM).Fórmula:C14H11NO4Pureza:98.67% - 99.03%Forma y color:SolidPeso molecular:257.24Ref: TM-T10860
2mg47,00€5mg70,00€10mg107,00€25mg216,00€50mg350,00€100mg542,00€200mg778,00€500mg1.169,00€1mL*10mM (DMSO)70,00€CGP60474
CAS:CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.Fórmula:C18H18ClN5OPureza:99.81%Forma y color:SolidPeso molecular:355.82Ref: TM-T14943
1mg35,00€2mg48,00€5mg74,00€10mg97,00€25mg187,00€50mg331,00€100mg547,00€1mL*10mM (DMSO)82,00€D-64131
CAS:D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.Fórmula:C16H13NO2Pureza:99.48% - 99.67%Forma y color:SolidPeso molecular:251.28PKCε (85-92)
CAS:PKCε (85-92) is a biologically active peptide that functions as a specific activator of ε-PKC and induces MARCKS phosphorylation in wild-type cells, but doesFórmula:C39H54N10O14Pureza:98%Forma y color:SolidPeso molecular:886.9Schaftoside
CAS:Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.Fórmula:C26H28O14Pureza:100% - 99.32%Forma y color:SolidPeso molecular:564.49Ref: TM-T3898
1mg42,00€5mg85,00€10mg111,00€25mg210,00€50mg311,00€100mg467,00€200mg653,00€1mL*10mM (DMSO)95,00€FAK-IN-12
FAK-IN-12 (Compound 12S) is a selective FAK inhibitor with an IC50 of 47 nM.Pureza:98%Forma y color:Odour SolidTR-14035
CAS:TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).Fórmula:C24H21Cl2NO5Pureza:98.98%Forma y color:SolidPeso molecular:474.33Ref: TM-T5310
1mg52,00€5mg105,00€10mg170,00€25mg298,00€50mg430,00€100mg605,00€200mg815,00€1mL*10mM (DMSO)111,00€Go 6983
CAS:Go 6983 is a pan-PKC inhibitor targeting PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, exhibiting IC50 values of 7 nM, 7 nM, 6 nM, 10 nM, and 60 nM, respectively.Fórmula:C26H26N4O3Pureza:98.41% - 99.04%Forma y color:SolidPeso molecular:442.51Ref: TM-T6313
1mg43,00€2mg55,00€5mg84,00€10mg126,00€25mg245,00€50mg388,00€100mg563,00€1mL*10mM (DMSO)88,00€KHS 101
CAS:KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.Fórmula:C18H21N5SPureza:98.00%Forma y color:SolidPeso molecular:339.46AKT-IN-18
AKT-IN-18, an Akt inhibitor, demonstrates an IC50 value of 69.45 μM in A549 cells, effectively impeding Akt activity.Fórmula:C19H14ClN5O2SPureza:98%Forma y color:SolidPeso molecular:411.864-Isopropoxybenzoic acid
CAS:4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.Fórmula:C10H12O3Pureza:98.58%Forma y color:White To Off-White PowderPeso molecular:180.2
