Heterociclos con nitrógeno (N)

3,5-Dimethyl-2-hydroxymethyl-4-nitropyridine is a proton pump inhibitor that inhibits the H+,K+-ATPase enzyme of gastric parietal cells, which is responsible for acid secretion. This inhibition may be due to its ability to bind to the magnesium ion in this enzyme’s active site. 3,5-Dimethyl-2-hydroxymethyl-4-nitropyridine has been shown to inhibit the activity of the proton pump by binding to its anion binding site with high affinity and specificity. 3,5-Dimethyl-2-hydroxymethyl-4-nitropyridine also inhibits esomeprazole magnesium (EEM), a drug used in treatment of gastroesophageal reflux disease (GERD). It does so by competing with EEM for binding at the proton pump's anion binding site.

Please enquire for more information about 4-Chloro-5-iodo-2-methyl-7H-pyrrolo[2,3-d]pyrimidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Ethylindole-2-carboxylic acid is an organic compound that is a decarboxylation product of indole. It can be obtained by catalytic dehydrogenation of ethyl ester or 5-ethylindole-2-carboxylic acid. It has been shown to inhibit the growth of bacteria and fungi, as well as to have anti-inflammatory properties.

4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol is a chemical compound that inhibits the growth of microorganisms. It is used as a cross-linking agent, osmosis inhibitor, and encapsulation aid in pharmaceutical preparations. It is also an inhibitor for chemical pesticides and has been studied as a possible treatment for depression. 4-[4-Chloro-3-(trifluoromethyl)phenyl]-4-piperidinol binds to metal hydroxides by hydrogen bonding, which blocks the ability of bacteria to utilize water vapor. This leads to cell death by dehydration. Model studies have shown that it can be a useful treatment for depression because it blocks the reuptake of serotonin into the presynaptic terminal of neurons, increasing its levels in the brain.

Please enquire for more information about 3-Chloro-4-hydroxypyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases. References Li, X., et al.: PCT Int. Appl., WO 2014183520 A1 20141120 (2014)

6-Methylpyrazin-2-ol is an acrylonitrile amide. It has been shown to be a potent fungicide, with a high degree of activity against a range of plant diseases. 6-Methylpyrazin-2-ol also displays a fluorescent characteristic, which can be detected by spectroscopic methods such as chromatography or fluorescence. This compound has been shown to have strong oral toxicity in rats and mice. 6-Methylpyrazin-2-ol is readily soluble in water and can be used for the prevention of corrosion on metals and paints, as well as for the preparation of dyes and pharmaceuticals.