Heterociclos con nitrógeno (N)

Applications 4-[4-[(5R)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone Hydrochloride is an intermediate in the synthesis of ent-Rivaroxaban (R538005), the R-isomer of Rivaroxaban (R538000), which is a novel antithrombotic agent. References Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),

Applications 4-Aminopiperidine-3,3,4,5,5-d5 (CAS# 1219803-60-7) is a useful isotopically labeled research compound.

Please enquire for more information about 3-Amino-6-isopropyl-2-methylthieno[2,3-d]pyrimidin-4(3H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Ethylpyridine is a type of compound that has been found in bacteria. It has been shown to be a mitochondrial membrane potential inhibitor and matrix molecules inducer. 3-Ethylpyridine also inhibits the mitochondrial pathway of 2-ethylpyridine, which is a major metabolite of nicotine in mammals. This inhibition leads to lung cancer. 3-Ethylpyridine can be used as an alternative to chemotherapeutic agents for lung cancer treatment.

2-Phenylimidazole is used to prepare complex compounds with ruthenium(III) and also as an intermediate for agrochemical, pharmaceutical and specialty products. It also finds its application as a curing agent for epoxy resins and polyurethane. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Please enquire for more information about 8'-Chloro-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline] including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3',4'-Dihydro-2'H-spiro[cyclopentane-1,1'-pyrrolo[1,2-a]pyrazine] including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (3S)-4-Boc-1-carboxymethyl-3-methyl-piperazin-2-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

4,6-Dichloro-1H-pyrazolo[4,3-c]pyridine is a reagent that has been used as a building block for the synthesis of other compounds. It is also used in the preparation of a variety of organic compounds. 4,6-Dichloro-1H-pyrazolo[4,3-c]pyridine is soluble in organic solvents such as chloroform and ethanol, and can be stored at room temperature. This compound reacts with acids to produce an acid chloride that are useful for the formation of amides and esters. This product has been shown to have a high quality and is suitable for use in research or development.

Please enquire for more information about 1-(Tetrahydro-2H-pyran-4-yl)piperidine-3-carboxylic acid hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Ethyl 5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 2,5-Di-4-pyridinylpyrazine is a compound used in the preparation of isonicotonic acid derivatives used in the chemotherapy of tuberculosis. References Cymerman-Craig, J., et al.: J Chem Soc., 4315-20 (1955);

Please enquire for more information about 2,3-Difluoropyridine-5-boronic acid pinacol ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-Chloropyridine-2-carbonylchloride is a potent antitumor agent that belongs to the class of quinoline derivatives. It has been shown to inhibit protein synthesis and cancer cell growth in vitro and in vivo. The antitumor activity of 4-Chloropyridine-2-carbonylchloride may be due to its ability to inhibit the activation of growth factors such as epidermal growth factor (EGF). 4-Chloropyridine-2-carbonylchloride also inhibits DNA synthesis by inhibiting the activity of DNA polymerase alpha. This compound binds to surface methodology on cells, which may explain its potent antitumor activity.

Please enquire for more information about (2,3-Difluoropyridin-4-yl)boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

2,6-Dibromopyridine (2,6-DBP) is a chemical compound that has been used in the synthesis of other organic compounds. It is an aromatic heterocycle with nitrogen atoms at the 2 and 6 positions. 2,6-DBP is a monosubstituted pyridine derivative that undergoes a palladium-catalyzed coupling reaction with an aryl halide to form pyrazoles. This process can be done unsymmetrically by protonating the 2 position of the dibromopyridine molecule. The presence of serine protease has been shown to promote this reaction by increasing the surface area of the substrate.

Please enquire for more information about 7-(3,4-Dimethoxyphenyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4,5-Dihydro-1H-imidazol-2-amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Hydrazinyl-4-(Trifluoromethyl)-5-Pyrimidinecarboxylic Acid Methyl Ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

1,4-Dinitrosopiperazine is a chemical compound that has been used as an anthelmintic drug and for the treatment of cancer. It is a structural analog of piperazine, but with two nitro groups on each amine group. 1,4-Dinitrosopiperazine can be synthesized from 2,6-diamino-3-nitropyridine and formaldehyde in the presence of sodium nitrite and potassium hydroxide. The reaction mechanism is similar to that of piperazine but with a different product. 1,4-Dinitrosopiperazine can be found in urine samples and reacts with sulfhydryl groups at cysteine residues to form stable adducts. In vitro studies have shown that these adducts inhibit acetylcholinesterase activity and may be responsible for its anticancer properties. 1,4-Dinitrosopiperazine inhibits the growth of squamous carcin

Please enquire for more information about 4-Chloro-5-nitro-2-hydroxypyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications N-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-3-carboxamide hydrochloride (cas# 1219957-27-3) is a useful research chemical.

Please enquire for more information about 2-Chloro-N'-hydroxypyridine-4-carboximidamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-(3-Hydroxyphenyl)-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Methyl-4-piperidone is a magnetic compound that can be used as an acid catalyst in the synthesis of pharmaceuticals. It is obtained by the reaction of propionic anhydride with aldehyde. This compound is synthesized through the use of various techniques and has been shown to have analgesic properties. 3-Methyl-4-piperidone can be reused and its conformation can be determined through techniques such as proton NMR spectroscopy, which can help in prioritizing this compound for further study.

2-Acetyl-6-methoxypyridine is a reactive intermediate that is used in the synthesis of morpholine and piperidine. This compound has been shown to have anti-cancer properties, with cytotoxic effects on HCT116 cells. It has also been shown to be an organometallic compound that can interact with nucleophilic groups. 2-Acetyl-6-methoxypyridine may also be used as an antibacterial agent, although there are no studies that have investigated its cellular interactions.

Please enquire for more information about Methyl 2-(4-fluorophenyl)imidazo[1,2-a]pyridine-6-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Methyl-5-nitroimidazole-1-propanol (2MI) is a matrix effect correction reagent that can be used to reconstitute the original concentrations of drugs in plasma and urine samples. It is also used for sample preparation, validation and quality control. 2MI has been shown to bind with cervical cancer cells, which may be due to its ability to bind with drug receptors on the surface of these cells. A liquid chromatography-mass spectrometry (LC-MS/MS) method was developed to measure 2MI in plasma and urine samples. The method was validated using test samples and showed good agreement with the target concentration.

Please enquire for more information about 1-[(1-Methyl-1H-pyrazol-4-yl)methyl]piperazine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-Bromo-2-hydrazinyl-3-nitropyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (3R,4S)-rel-3-methyl-N-phenyl-1-benzyl-4-piperidinamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Thiazolo[4,5-d]pyrimidine-5,7-diol is a synthetic compound that is used as an anti-fungal agent. It inhibits the synthesis of RNA in fungi by deaminating their ribosomal RNA. The effect of this drug on fungi is irreversible and it does not require direct contact with the cells. Thiazolo[4,5-d]pyrimidine-5,7-diol has been shown to be effective against colocynthis and Traceless (a fungus that causes ringworm). It also has anti-inflammatory effects, which may be due to its inhibition of prostaglandin synthesis.

2-Methyl-3-(methylthio)pyrazine is a surface methodology that can be used to detect sulfide in high concentrations. It is metastable and can be detected by solid phase microextraction. This compound has been shown to react with alkylpyrazines and aldehydes to produce quinoxalines, which are used as model systems for the study of molecular ions. 2-Methyl-3-(methylthio)pyrazine is also used in headspace analysis, which involves the use of microextraction techniques to identify reaction products such as furfuryl acetate.

Please enquire for more information about (4-Pyridin-4-yl-1H-pyrazol-1-yl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Chloro-5-nitropyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-Acetoxymethylpyridine is a synthetic compound that belongs to the anion group. It has been used as a stationary phase in gas chromatography and as an eluent in liquid chromatography. 4-Acetoxymethylpyridine is also commonly used as a reagent to convert alcohols into their corresponding pyridinium salts. This compound undergoes nucleophilic attack by hydroxide ions, which leads to bond cleavage and the formation of the n-oxide. 4-Acetoxymethylpyridine is soluble in polar solvents such as ethanol, but insoluble in nonpolar solvents such as hexane. Spectroscopic data indicates that this compound contains an oxygen atom with two hydrogen atoms bonded to it, along with four carbon atoms and two nitrogen atoms.

Please enquire for more information about 1-[(4-Fluorobenzyl)sulfonyl]piperidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-[4-(2-{(2R)-2-Cyclopentyl-5-[(5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-4-hydroxy-6-oxo-3,6-dihydro-2H-pyran-2-yl}e thyl)-2 -fluorophenyl]-2 methylpropane nitrile (GSK1265744) is a replication inhibitor that targets the HIV virus and inhibits its ability to replicate. GSK1265744 is a prodrug that is activated by protease and is phosphorylated intracellularly by NS3 protease. It has been shown to be effective against drug resistant mutants of HIV and has a high level of resistance in human serum and plasma. GSK1265744 also has pharmacokinetic properties that are similar to other HIV

Please enquire for more information about 2-Hydroxy-3-iodo-5-methylpyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6,6''-Dibromo-2,2':6',2''-terpyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-[2-(Methyl-2-pyridinyl)amino]ethoxylnitrobenzene including the price, delivery time and more detailed product information at the technical inquiry form on this page

2,3-Diamino-6-chloropyridine is a chemical compound that is an ethylated derivative of 2,3-diamino-6-chloropyridine. It has been shown to be hydrolyzed by esters and in acidic environments, although it can also be esterified with ethanolates or malonates. 2,3-Diamino-6-chloropyridine is a mixture of compounds with different structures that are cyclized in different ways. The most common form of this compound is its morpholine derivative, which is formed when the amine group on the nitrogen atom reacts with a carbonyl group (C=O) on another molecule. This reaction results in the formation of an amide bond between the two molecules. 2,3-Diamino-6-chloropyridine can also react with an alcohol to form an ester bond. This reaction produces a 2,3 diaminometh

Please enquire for more information about 4-(4-Methoxyphenyl)-4,5,6,7-tetrahydrothieno[3.2-c]pyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Pyrazine-2-carboxylic acid is a potent inhibitor of bacterial x-lactamase. It was found that the inhibition of x-lactamase by pyrazine-2-carboxylic acid could be attributed to hydrogen bonding interactions with the active site of the enzyme and a high rate constant for the reaction. The antibacterial efficacy of pyrazine-2-carboxylic acid against wild type Streptococcus pneumoniae and methicillin resistant Staphylococcus aureus (MRSA) was tested and found to be comparable to that of benzylpenicillin. Pyrazine-2-carboxylic acid also has biological properties, such as an inhibitory effect on protein synthesis in bacteria, which may be due to its ability to bind to ribosomes.